Tumor accumulation, degradation and pharmacokinetics of elastin-like polypeptides in nude mice

Journal of Controlled Release

Volumn 116, Issue 2 SPEC. ISS., 2006, Pages 170-178

  Liu, Wenge ^a   Dreher, Matthew R ^a   Furgeson, Darin Y ^a   Peixoto, Katia V ^b   Yuan, Hong ^b   Zalutsky, Michael R ^b   Chilkoti, Ashutosh ^a  

^a Duke University   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Carbon 14; Degradation; Drug delivery; Elastin like polypeptide; Macromolecular drug carriers; Pharmacokinetics; Tumor localization

Indexed keywords

BIODEGRADATION; BIODIVERSITY; BIOSYNTHESIS; CARBON; CONTROLLED DRUG DELIVERY; ESCHERICHIA COLI; PHARMACOKINETICS; TUMORS;

CARBON-14; ELASTIN LIKE POLYPEPTIDE; MACROMOLECULAR DRUG CARRIERS; TUMOR LOCALIZATION;

POLYPEPTIDES;

ELASTIN; ELASTIN 1; ELASTIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; BIODEGRADATION; BIOSYNTHESIS; CONTROLLED STUDY; DISEASE MODEL; DRUG HALF LIFE; ESCHERICHIA COLI; FEMALE; IN VITRO STUDY; ISOTOPE LABELING; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SERUM; TUMOR; TUMOR LOCALIZATION;

EID: 33845223376     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.06.026     Document Type: Article

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