-
1
-
-
0017887062
-
Modification of E. coli L-asparaginase with polyethylene glycol: Disappearance of binding ability to anti-asparaginase serum
-
Ashihara, Y., Kono, T., Yamazaki, S., and Inada, Y. (1978) Modification of E. coli L-asparaginase with polyethylene glycol: Disappearance of binding ability to anti-asparaginase serum. Biochem. Biophys. Res. Commun. 83, 385-391.
-
(1978)
Biochem. Biophys. Res. Commun.
, vol.83
, pp. 385-391
-
-
Ashihara, Y.1
Kono, T.2
Yamazaki, S.3
Inada, Y.4
-
2
-
-
0025089844
-
Clearance of charged and uncharged dextran from normal and injured lungs
-
Barrowcliffe, M. P., Zanelli, G. D., Ellison, D., and Jones, J. G. (1990) Clearance of charged and uncharged dextran from normal and injured lungs. J. Appl. Physiol. 68, 341-347.
-
(1990)
J. Appl. Physiol.
, vol.68
, pp. 341-347
-
-
Barrowcliffe, M.P.1
Zanelli, G.D.2
Ellison, D.3
Jones, J.G.4
-
4
-
-
0020085780
-
Immunological effects of native and polyethylene glycol-modified asparaginases from Vibrio succinogenes and Escherichia coli in normal and tumor-bearing mice
-
Bendich, A., Abuchowski, A., and Davis, F. F. (1982) Immunological effects of native and polyethylene glycol-modified asparaginases from Vibrio succinogenes and Escherichia coli in normal and tumor-bearing mice. Clin. Exp. Immunol. 48, 273-278.
-
(1982)
Clin. Exp. Immunol.
, vol.48
, pp. 273-278
-
-
Bendich, A.1
Abuchowski, A.2
Davis, F.F.3
-
5
-
-
0023788067
-
Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules
-
Dvorak, H. F., Nagy, J. A., Dvorak, J. T., and Dvorak, A. M. (1988) Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules. Am. J. Pathol. 133, 95-109.
-
(1988)
Am. J. Pathol.
, vol.133
, pp. 95-109
-
-
Dvorak, H.F.1
Nagy, J.A.2
Dvorak, J.T.3
Dvorak, A.M.4
-
6
-
-
0842279809
-
Liposome formations with prolonged circulation time in blood and enhanced uptake by tumors
-
Gabizin, A., and Papahadjopoulos, D. (1988) Liposome formations with prolonged circulation time in blood and enhanced uptake by tumors. Proc. Natl. Acad. Sci. USA 85, 6949-6953.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 6949-6953
-
-
Gabizin, A.1
Papahadjopoulos, D.2
-
8
-
-
0025072412
-
Biliary excretion of mitomycin C dextran conjugates in relation to physicochemical characteristics of carrier dextran
-
Hashida, M., Atsumi, R., Nishida, K., Nakane, S., Takakura, Y., and Sezaki, H. (1990) Biliary excretion of mitomycin C dextran conjugates in relation to physicochemical characteristics of carrier dextran. J. Pharmacobiodyn. 13, 441-447.
-
(1990)
J. Pharmacobiodyn.
, vol.13
, pp. 441-447
-
-
Hashida, M.1
Atsumi, R.2
Nishida, K.3
Nakane, S.4
Takakura, Y.5
Sezaki, H.6
-
9
-
-
0023146216
-
Treatment of adenosine deaminase deficiency with polyethylene glycol-modified adenosine deaminase
-
Hershfield, M. S., Buckley, R. H., Greenburg, M. L., Melton, A. L., Schiff, R., Hatem, C., Kurtzberg, J., Marken, M. L., Kobayashi, R. H., Kobayashi, A. L., and Abuchowski, A. N. (1987) Treatment of adenosine deaminase deficiency with polyethylene glycol-modified adenosine deaminase. N. Engl. J. Med. 316, 589-596.
-
(1987)
N. Engl. J. Med.
, vol.316
, pp. 589-596
-
-
Hershfield, M.S.1
Buckley, R.H.2
Greenburg, M.L.3
Melton, A.L.4
Schiff, R.5
Hatem, C.6
Kurtzberg, J.7
Marken, M.L.8
Kobayashi, R.H.9
Kobayashi, A.L.10
Abuchowski, A.N.11
-
10
-
-
0022653255
-
Differential macromolecular leakage from the vasculature of tumors
-
Heuser, L. S., and Miller, F. N. (1986) Differential macromolecular leakage from the vasculature of tumors. Cancer 57, 461-164.
-
(1986)
Cancer
, vol.57
, pp. 461-1164
-
-
Heuser, L.S.1
Miller, F.N.2
-
11
-
-
0023219734
-
Transport of molecules in the tumor interstitium: A review
-
Jain, R. H. (1987) Transport of molecules in the tumor interstitium: A review. Cancer Res. 47, 3039-3051.
-
(1987)
Cancer Res.
, vol.47
, pp. 3039-3051
-
-
Jain, R.H.1
-
12
-
-
0023881071
-
Delivery of glutathione, as a dextran conjugate, into the liver
-
Kaneo, Y., Tanaka, T., Fujihara, Y., Mori, H., and Iguchi, S. (1988) Delivery of glutathione, as a dextran conjugate, into the liver. Int. J. Pharm. 44, 265-267.
-
(1988)
Int. J. Pharm.
, vol.44
, pp. 265-267
-
-
Kaneo, Y.1
Tanaka, T.2
Fujihara, Y.3
Mori, H.4
Iguchi, S.5
-
13
-
-
0026567096
-
Role of liposome size and RES blockage in controlling biodistribution and tumor uptake of GM1-containing liposomes
-
Liu, D., Mori, A., and Huang, L. (1992) Role of liposome size and RES blockage in controlling biodistribution and tumor uptake of GM1-containing liposomes. Biochim. Biophys. Acta 1104, 95-101.
-
(1992)
Biochim. Biophys. Acta
, vol.1104
, pp. 95-101
-
-
Liu, D.1
Mori, A.2
Huang, L.3
-
14
-
-
0024839642
-
Tumoritropic and lymphotropic principles of macromolecular drugs
-
Maeda, H., and Matsumura, Y. (1989) Tumoritropic and lymphotropic principles of macromolecular drugs. Crit. Rev. Ther. Drug. Carrier Syst. 6, 193-210.
-
(1989)
Crit. Rev. Ther. Drug. Carrier Syst.
, vol.6
, pp. 193-210
-
-
Maeda, H.1
Matsumura, Y.2
-
15
-
-
0023138769
-
Covalent linkage of carboxypeptidase G2 to soluble dextran - 11: In vivo distribution and fate of conjugate
-
Melton, R. G., Wiblin, C. N., Foster, R. L., and Sherwood, R. F. (1987) Covalent linkage of carboxypeptidase G2 to soluble dextran - 11: In vivo distribution and fate of conjugate. Biochem. Pharmacol. 36, 105-112.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 105-112
-
-
Melton, R.G.1
Wiblin, C.N.2
Foster, R.L.3
Sherwood, R.F.4
-
16
-
-
0000268659
-
Syntheses and characterization of polymeric derivatives of the antitumor agent
-
Przybyski, M., Fell, E., and Ringsdorf, H. (1978) Syntheses and characterization of polymeric derivatives of the antitumor agent. Makromol. Chem. 179, 1733-1791.
-
(1978)
Makromol. Chem.
, vol.179
, pp. 1733-1791
-
-
Przybyski, M.1
Fell, E.2
Ringsdorf, H.3
-
17
-
-
0026694788
-
Passive tumor targeting of soluble macromolecules and drug conjugates
-
Seymour, L. W. (1992) Passive tumor targeting of soluble macromolecules and drug conjugates. Ther. Drug. Carrier Syst. 9, 135-187.
-
(1992)
Ther. Drug. Carrier Syst.
, vol.9
, pp. 135-187
-
-
Seymour, L.W.1
-
18
-
-
0025200957
-
Pharmacokinetic analysis of immunotoxin uptake in solid tumors: Role of plasma kinetics, capillary permeability, and binding
-
Sung, C., Youle, R. J., and Dedrick, R. L. (1990) Pharmacokinetic analysis of immunotoxin uptake in solid tumors: Role of plasma kinetics, capillary permeability, and binding. Cancer Res. 50, 7382-7392.
-
(1990)
Cancer Res.
, vol.50
, pp. 7382-7392
-
-
Sung, C.1
Youle, R.J.2
Dedrick, R.L.3
-
19
-
-
0025148495
-
Disposition characteristics of macromolecules in tumor-bearing mice
-
Takakura, Y., Atumi, R., Hashida, M., and Sezaki, H. (1990) Disposition characteristics of macromolecules in tumor-bearing mice. Pharm. Res. 7, 339-346.
-
(1990)
Pharm. Res.
, vol.7
, pp. 339-346
-
-
Takakura, Y.1
Atumi, R.2
Hashida, M.3
Sezaki, H.4
-
20
-
-
0002079949
-
Disposition and tumor localization of mitomycin C-dextran conjugates in mice
-
Takakura, Y., Takagi, A., Hashida, M., and Sezaki, H. (1987) Disposition and tumor localization of mitomycin C-dextran conjugates in mice. Pharm. Res. 4, 223-230.
-
(1987)
Pharm. Res.
, vol.4
, pp. 223-230
-
-
Takakura, Y.1
Takagi, A.2
Hashida, M.3
Sezaki, H.4
-
21
-
-
0029000870
-
Effect of the size and fluidity of liposomes on their accumulation in tumors: A presumption of their interaction with tumors
-
Uchiyama, K., Nagayasu, A., Yamagiwa, Y., Nishida, T., Harashima, H., and Kiwada, H. (1995) Effect of the size and fluidity of liposomes on their accumulation in tumors: A presumption of their interaction with tumors. Int. J. Pharm. 121, 195-203.
-
(1995)
Int. J. Pharm.
, vol.121
, pp. 195-203
-
-
Uchiyama, K.1
Nagayasu, A.2
Yamagiwa, Y.3
Nishida, T.4
Harashima, H.5
Kiwada, H.6
-
22
-
-
0028970433
-
Body distribution of dextran derivatives with electric charges after intravenous administration
-
Yamaoka, T., Kuroda, M., Tabata, Y., and Ikada, Y. (1995) Body distribution of dextran derivatives with electric charges after intravenous administration. Int. J. Pharm. 113, 149-157.
-
(1995)
Int. J. Pharm.
, vol.113
, pp. 149-157
-
-
Yamaoka, T.1
Kuroda, M.2
Tabata, Y.3
Ikada, Y.4
-
23
-
-
0002458180
-
Body distribution profile of polysaccharides after intravenous administration
-
Yamaoka, T., Tabata, Y., and Ikada, Y. (1993) Body distribution profile of polysaccharides after intravenous administration. Drug Deliv. 1, 75-82.
-
(1993)
Drug Deliv.
, vol.1
, pp. 75-82
-
-
Yamaoka, T.1
Tabata, Y.2
Ikada, Y.3
-
24
-
-
0028337034
-
Distribution and tissue uptake of polyethylene glycol with different molecular weights after intravenous administration to mice
-
Yamaoka, T., Tabata, Y., and Ikada, Y. (1994) Distribution and tissue uptake of polyethylene glycol with different molecular weights after intravenous administration to mice. J. Pharm. Sci. 83, 601-606.
-
(1994)
J. Pharm. Sci.
, vol.83
, pp. 601-606
-
-
Yamaoka, T.1
Tabata, Y.2
Ikada, Y.3
-
25
-
-
0029015672
-
Comparison of body distribution of poly(vinyl alchol) with other water-soluble polymers after intravenous administration
-
Yamaoka, T., Tabata, Y., and Ikada, Y. (1995) Comparison of body distribution of poly(vinyl alchol) with other water-soluble polymers after intravenous administration. J. Pharm. Pharmacol. 47, 470-486.
-
(1995)
J. Pharm. Pharmacol.
, vol.47
, pp. 470-486
-
-
Yamaoka, T.1
Tabata, Y.2
Ikada, Y.3
-
26
-
-
0022908309
-
Characterization of polyethylene glycol-modified L-asparaginase from Escherichia coli and its application to therapy of leukemia
-
Yoshimoto, T., Nishimura, H., Saito, Y., Sakurai, K., Kamisaki, Y., Wada, H., Sako, M., Tsujino, G., and Inada, Y. (1986) Characterization of polyethylene glycol-modified L-asparaginase from Escherichia coli and its application to therapy of leukemia. Jpn. J. Cancer Res. (Gann ) 77, 1264-1270.
-
(1986)
Jpn. J. Cancer Res. (Gann )
, vol.77
, pp. 1264-1270
-
-
Yoshimoto, T.1
Nishimura, H.2
Saito, Y.3
Sakurai, K.4
Kamisaki, Y.5
Wada, H.6
Sako, M.7
Tsujino, G.8
Inada, Y.9
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