Postoperative recurrence of Crohn's disease: The enemy is within the fecal stream

Gastroenterology

Volumn 114, Issue 2, 1998, Pages 398-400

  Sartor, R B ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; METRONIDAZOLE;

ANTIGEN PRESENTING CELL; BACTEROIDES FRAGILIS; CELL DENSITY; CROHN DISEASE; EDITORIAL; HISTOPATHOLOGY; HLA SYSTEM; ILEOSTOMY; PATHOGENESIS; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RECURRENT DISEASE; SYMPTOMATOLOGY;

EID: 0031939085     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(98)70492-5     Document Type: Editorial

References (24)

1. P Rutgeerts K Geboes G Vantrappen R Kerremans JL Coenegrachts G Coremans Natural history of recurrent Crohn's disease at the ileocolonic anastomosis after curative surgery Gut 25 1984 665 672
2. F Pallone M Boirivant MA Stazi R Cosintino C Prantera A Torsoli Analysis of clinical course of postoperative recurrence in Crohn's disease of distal ileum Dig Dis Sci 37 1992 215 219
3. DB Sachar K Subramani K Mauer S Rivera-MacMurray P Turtel CA Bodian AJ Greenstein Patterns of postoperative recurrence in fistulizing and stenotic Crohn's disease. A retrospective cohort study of 71 patients J Clin Gastroenterol 22 1996 114 116
4. P Rutgeerts K Geboes G Vantrappen J Beyls R Kerremans M Hiele Predictability of the postoperative course of Crohn's disease Gastroenterology 99 1990 956 963
5. GNJ Tytgat CJJ Mulder WH Brummelkamp Endoscopic lesions in Crohn's disease early after ileocecal resection Endoscopy 20 1988 260 262
6. P Rutgeerts K Goboes M Peeters M Hiele F Penninckx R Aerts R Kerremans G Vantrappen Effect of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum Lancet 338 1991 771 774
7. GR D'Haens K Geboes M Peeters F Baert F Penninckx P Rutgeerts Early lesions of recurrent Crohn's disease caused by infusion of intestinal contents in excluded ileum Gastroenterology 114 1998 262 267
8. RB Sartor Enteric microflora in IBD: pathogens or commensals? Inflam Bowel Dis 3 1997 230 235
9. JH Burman H Thompson WT Cooke JA Williams The effects of diversion of intestinal contents on the progress of Crohn's disease of the large bowel Gut 12 1971 11 15
10. PH Harper SC Truelove ECG Lee MGW Kettlewell DP Jewell Split ileostomy and ileocolostomy for Crohn's disease of the colon and ulcerative colitis: a 20 year survey Gut 24 1983 106 113
11. PH Harper ECG Lee MGW Kettlewell MK Bennett DP Jewell Role of the faecal stream in the maintenance of Crohn's colitis Gut 26 1985 279 284
12. R Fasoli MGW Kettlewell N Mortensen DP Jewell Response to faecal challenge in defunctioned colonic Crohn's disease: prediction of long-term course Br J Surg 77 1990 616 617
13. P Rutgeerts M Hiele K Geboes M Peeters F Penninckx R Aerts R Kerremans Controlled trial of metronidazole treatment for prevention of Crohn's recurrence after ileal resection Gastroenterology 108 1995 1617 1621
14. B Sadlack H Merz H Schorle A Schimpl AC Feller I Horak Ulcerative colitis–like disease in mice with a disrupted interleukin-2 gene Cell 75 1993 253 261
15. 2 microglobulin transgenic rats J Clin Invest 98 1996 945 953
16. L Dianda AM Hanby NA Wright A Sebesteny AC Hayday MJ. Owen T cell receptor-αβ–deficient mice fail to develop colitis in the absence of a microbial environment Am J Pathol 150 1997 91 97
17. MR Keighley Y Arabi F Dimock DW Burdon RN Allan J. Alexander-Williams Influence of inflammatory bowel disease on intestinal microflora Gut 19 1978 1099 1104
18. JJ Powell CC Ainley IM Mason MD Kendall EA Sankey AP Dhillon RP. Thompson Characterization of inorganic microparticles in pigment cells of human gut associated lymphoid tissue Gut 38 1996 390 395
19. Duchmann R, Kaiser I, Hermann E, Mayet W, Ewe K, Mayer zum Buschenfelde H-H. Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD). Clin Exp Immunol 11995;102:448-455.
20. A Mizoguchi E Mizoguchi C Chiba AK. Bhan Role of appendix in the development of inflammatory bowel disease in TCR-α mutant mice J Exp Med 184 1996 707 715
21. HC Rath JS Ikeda KH Wilson RB. Sartor Varying cecal bacterial loads influences colitis and gastritis in HLA-B27 transgenic rats (abstr) Gastroenterology 112 1997 A938
22. B Scammell MS Ambrose J Alexander-Williams RN Allan MRB. Keighley Recurrent small bowel Crohn's disease is more frequent after subtotal colectomy and ileorectal anastomosis than proctocolectomy Dis Colon Rectum 28 1985 770 771
23. JL Cameron SR Hamilton J Coleman JV Sitzmann TM. Bayless Patterns of ileal recurrence in Crohn's disease. A prospective randomized study Ann Surg 215 1992 546 551
24. P Desreumaux E Brandt L Gambiez D Emilie K Geboes O Klein N Ectors A Cortot M Capron JF. Colombel Distinct cytokine patterns in early and chronic ileal lesions of Crohn's disease Gastroenterology 113 1997 118 126