-
1
-
-
0029912274
-
Mechanisms of nucleoside analog antiviral activity and resistance during human immunodeficiency virus reverse transcription
-
Arts, E.J. and Wainberg, M.A. (1996) Mechanisms of nucleoside analog antiviral activity and resistance during human immunodeficiency virus reverse transcription. Antimicrob. Agents Chemother., 40, 527-540.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 527-540
-
-
Arts, E.J.1
Wainberg, M.A.2
-
2
-
-
0026652956
-
A possible role for cysteine residues in the fidelity of DNA synthesis exhibited by the reverse transcriptase of human immunodeficiency viruses type 1 and type 2
-
Bakhanashvili, M. and Hizi, A. (1992) A possible role for cysteine residues in the fidelity of DNA synthesis exhibited by the reverse transcriptase of human immunodeficiency viruses type 1 and type 2. FEBS Lett., 304, 289-243.
-
(1992)
FEBS Lett.
, vol.304
, pp. 289-1243
-
-
Bakhanashvili, M.1
Hizi, A.2
-
3
-
-
0024324362
-
Substrate binding in human immunodeficiency virus reverse transcriptase. An analysis of pyridoxal 5′-phosphate sensitivity and identification of lysine 263 in the substrate-binding domain
-
Basu, A., Tirumalai, R.S. and Modak, M.J. (1989) Substrate binding in human immunodeficiency virus reverse transcriptase. An analysis of pyridoxal 5′-phosphate sensitivity and identification of lysine 263 in the substrate-binding domain. J. Biol. Chem., 264, 8746-8752.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 8746-8752
-
-
Basu, A.1
Tirumalai, R.S.2
Modak, M.J.3
-
4
-
-
0027424779
-
Kinetic analysis of template-primer interactions with recombinant forms of HIV-1 reverse transcriptase
-
Beard, W.A. and Wilson, S.H. (1993) Kinetic analysis of template-primer interactions with recombinant forms of HIV-1 reverse transcriptase. Biochemistry, 32, 9745-9753.
-
(1993)
Biochemistry
, vol.32
, pp. 9745-9753
-
-
Beard, W.A.1
Wilson, S.H.2
-
5
-
-
0027993294
-
Structure/function studies of human immunodeficiency virus type 1 reverse transcriptase. Alanine scanning mutagenesis of an α-helix in the thumb subdomain
-
Beard, W.A., Stahl, S.J., Kim, H.-R., Bebenek, K., Kumar, A., Strub, M.-P., Becerra, S.P., Kunkel, T.A. and Wilson, S.H. (1994) Structure/function studies of human immunodeficiency virus type 1 reverse transcriptase. Alanine scanning mutagenesis of an α-helix in the thumb subdomain. J. Biol. Chem., 269, 28091-28097.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 28091-28097
-
-
Beard, W.A.1
Stahl, S.J.2
Kim, H.-R.3
Bebenek, K.4
Kumar, A.5
Strub, M.-P.6
Becerra, S.P.7
Kunkel, T.A.8
Wilson, S.H.9
-
6
-
-
0002076195
-
The fidelity of retroviral reverse transcriptases
-
Skalka, A.M. and Goff, S.P. (eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
Bebenek, K. and Kunkel, T.A. (1993) The fidelity of retroviral reverse transcriptases. In Skalka, A.M. and Goff, S.P. (eds), Reverse Transcriptase. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 85-102.
-
(1993)
Reverse Transcriptase
, pp. 85-102
-
-
Bebenek, K.1
Kunkel, T.A.2
-
7
-
-
0027215750
-
Errorprone polymerization by HIV-1 reverse transcriptase. Contributions of template-primer misalignment, miscoding, and termination probability to mutational hot spots
-
Bebenek, K., Abbotts, J., Wilson, S.H. and Kunkel, T.A. (1993) Errorprone polymerization by HIV-1 reverse transcriptase. Contributions of template-primer misalignment, miscoding, and termination probability to mutational hot spots. J. Biol. Chem., 268, 10324-10334.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 10324-10334
-
-
Bebenek, K.1
Abbotts, J.2
Wilson, S.H.3
Kunkel, T.A.4
-
8
-
-
0029144027
-
Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain
-
Bebenek, K., Beard, W.A., Casas-Finet, J.R., Kim, H.-R., Darden, T.A., Wilson, S.H. and Kunkel, T.A. (1995) Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain. J. Biol. Chem., 270, 19516-19523.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19516-19523
-
-
Bebenek, K.1
Beard, W.A.2
Casas-Finet, J.R.3
Kim, H.-R.4
Darden, T.A.5
Wilson, S.H.6
Kunkel, T.A.7
-
9
-
-
0025898648
-
A general structure for DNA-dependent DNA polymerases
-
Blanco, L., Bernad, A., Blasco, M.A. and Salas, M. (1991) A general structure for DNA-dependent DNA polymerases. Gene, 100, 27-38.
-
(1991)
Gene
, vol.100
, pp. 27-38
-
-
Blanco, L.1
Bernad, A.2
Blasco, M.A.3
Salas, M.4
-
11
-
-
0023665197
-
DNA polymerase insertion fidelity. Gel assay for site-specific kinetics
-
Boosalis, M.S., Petruska, J. and Goodman, M.F. (1987) DNA polymerase insertion fidelity. Gel assay for site-specific kinetics. J. Biol. Chem., 262, 14689-14696.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 14689-14696
-
-
Boosalis, M.S.1
Petruska, J.2
Goodman, M.F.3
-
12
-
-
0026778009
-
Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates
-
Boyer, J.C., Bebenek, K. and Kunkel, T.A. (1992a) Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates. Proc. Natl Acad. Sci. USA, 89, 6919-6923.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 6919-6923
-
-
Boyer, J.C.1
Bebenek, K.2
Kunkel, T.A.3
-
13
-
-
0026500566
-
Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1
-
Boyer, P.L., Ferris, A.L. and Hughes, S.H. (1992b) Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1. J. Virol., 66, 1031-1039.
-
(1992)
J. Virol.
, vol.66
, pp. 1031-1039
-
-
Boyer, P.L.1
Ferris, A.L.2
Hughes, S.H.3
-
14
-
-
0028020216
-
Mutational analysis of the fingers and palm subdomains of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase
-
Boyer, P.L., Ferris, A.L., Clark, P., Whitmer, J., Frank, P., Tantillo, C., Arnold, E. and Hughes, S.H. (1994a) Mutational analysis of the fingers and palm subdomains of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase. J. Mol. Biol., 243, 472-483.
-
(1994)
J. Mol. Biol.
, vol.243
, pp. 472-483
-
-
Boyer, P.L.1
Ferris, A.L.2
Clark, P.3
Whitmer, J.4
Frank, P.5
Tantillo, C.6
Arnold, E.7
Hughes, S.H.8
-
15
-
-
0028341306
-
Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not
-
Boyer, P.L., Tantillo, C., Jacobo-Molina, A., Nanni, R.G., Ding, J., Arnold, E. and Hughes, S.H. (1994b) Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not. Proc. Natl Acad. Sci. USA, 91, 4882-4886.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 4882-4886
-
-
Boyer, P.L.1
Tantillo, C.2
Jacobo-Molina, A.3
Nanni, R.G.4
Ding, J.5
Arnold, E.6
Hughes, S.H.7
-
16
-
-
0021107939
-
Elementary steps in the DNA polymerase I reaction pathway
-
Bryant, F.R., Johnson, K.A. and Benkovic, S.J. (1983) Elementary steps in the DNA polymerase I reaction pathway. Biochemistry, 22, 3537-3546.
-
(1983)
Biochemistry
, vol.22
, pp. 3537-3546
-
-
Bryant, F.R.1
Johnson, K.A.2
Benkovic, S.J.3
-
17
-
-
0026029379
-
A mutant of DNA polymerase I (Klenow fragment) with reduced fidelity
-
Carroll, S.S., Cowart, M. and Benkovic, S.J. (1991) A mutant of DNA polymerase I (Klenow fragment) with reduced fidelity. Biochemistry, 30, 804-813.
-
(1991)
Biochemistry
, vol.30
, pp. 804-813
-
-
Carroll, S.S.1
Cowart, M.2
Benkovic, S.J.3
-
18
-
-
0027304470
-
Identification of the nucleotide binding site of HIV-1 reverse transcriptase using dTTP as a photoaffinity label
-
Cheng, N., Merrill, B.M., Painter, G.R., Frick, L.W. and Furman, P.A. (1993) Identification of the nucleotide binding site of HIV-1 reverse transcriptase using dTTP as a photoaffinity label. Biochemistry, 32, 7630-7634.
-
(1993)
Biochemistry
, vol.32
, pp. 7630-7634
-
-
Cheng, N.1
Merrill, B.M.2
Painter, G.R.3
Frick, L.W.4
Furman, P.A.5
-
19
-
-
0025040632
-
An attempt to unify the structure of polymerases
-
Delarue, M., Poch, O., Tordo, N., Moras, D. and Argos, P. (1990) An attempt to unify the structure of polymerases. Protein Engng, 3, 461-467.
-
(1990)
Protein Engng
, vol.3
, pp. 461-467
-
-
Delarue, M.1
Poch, O.2
Tordo, N.3
Moras, D.4
Argos, P.5
-
20
-
-
0022498061
-
Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV
-
Di Marzo Veronese, F., Copeland, T.D., DeVico, A.L., Rahman, R., Oroszlan, S., Gallo, R.C. and Sarngadharan, M.G. (1986) Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV. Science, 231, 1289-1291.
-
(1986)
Science
, vol.231
, pp. 1289-1291
-
-
Di Marzo Veronese, F.1
Copeland, T.D.2
DeVico, A.L.3
Rahman, R.4
Oroszlan, S.5
Gallo, R.C.6
Sarngadharan, M.G.7
-
21
-
-
0029644484
-
Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor α-APA R 95845 at 2.8 Å resolution
-
Ding, J. et al. (1995) Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor α-APA R 95845 at 2.8 Å resolution. Structure, 3, 365-379.
-
(1995)
Structure
, vol.3
, pp. 365-379
-
-
Ding, J.1
-
22
-
-
0027448958
-
Mutational studies of human DNA polymerase α. Identification of residues critical for deoxynucleotide binding and misinsertion fidelity of DNA synthesis
-
Dong, Q., Copeland, W.C. and Wang, T.S.-F. (1993) Mutational studies of human DNA polymerase α. Identification of residues critical for deoxynucleotide binding and misinsertion fidelity of DNA synthesis. J. Biol. Chem., 268, 24163-24174.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 24163-24174
-
-
Dong, Q.1
Copeland, W.C.2
Wang, T.S.-F.3
-
24
-
-
0028924567
-
Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors
-
Esnouf, R., Ren, J., Ross, C., Jones, Y., Stammers, D. and Stuart, D. (1995) Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors. Nature Struct. Biol., 2, 303-308.
-
(1995)
Nature Struct. Biol.
, vol.2
, pp. 303-308
-
-
Esnouf, R.1
Ren, J.2
Ross, C.3
Jones, Y.4
Stammers, D.5
Stuart, D.6
-
25
-
-
0342524024
-
Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants
-
Hizi, A., McGill, C. and Hughes, S.H. (1988) Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants. Proc. Natl Acad. Sci. USA, 85, 1218-1222.
-
(1988)
Proc. Natl Acad. Sci. USA
, vol.85
, pp. 1218-1222
-
-
Hizi, A.1
McGill, C.2
Hughes, S.H.3
-
26
-
-
0024519430
-
Human immunodeficiency virus J reverse transcriptase. Template binding, processivity, strand displacement synthesis, and template switching
-
Huber, H.E., McCoy, J.M., Seehra, J.S. and Richardson, C.C. (1989) Human immunodeficiency virus J reverse transcriptase. Template binding, processivity, strand displacement synthesis, and template switching. J. Biol. Chem., 264, 4669-4678.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 4669-4678
-
-
Huber, H.E.1
McCoy, J.M.2
Seehra, J.S.3
Richardson, C.C.4
-
27
-
-
0027318776
-
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 Å resolution shows bent DNA
-
Jacobo-Molina, A. et al. (1993) Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 Å resolution shows bent DNA. Proc. Natl Acad. Sci. USA, 90, 6320-6324.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 6320-6324
-
-
Jacobo-Molina, A.1
-
28
-
-
0026693137
-
Crystal structure at 3.5 Å resolution of HIV-1 reverse transcriptase complexed with an inhibitor
-
Kohlstaedt, L.A., Wang, J., Friedman, J.M., Rice, P.A. and Steitz, T.A. (1992) Crystal structure at 3.5 Å resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science, 256, 1783-1790.
-
(1992)
Science
, vol.256
, pp. 1783-1790
-
-
Kohlstaedt, L.A.1
Wang, J.2
Friedman, J.M.3
Rice, P.A.4
Steitz, T.A.5
-
29
-
-
0028323494
-
Interactions between drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase
-
Larder, B.A. (1994) Interactions between drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase. J. Gen. Virol., 75, 951-957.
-
(1994)
J. Gen. Virol.
, vol.75
, pp. 951-957
-
-
Larder, B.A.1
-
30
-
-
0024706946
-
Infectious potential of human immunodeficiency virus type 1 reverse transcriptase mutants with altered inhibitor sensitivity
-
Larder, B.A., Kemp, S.D. and Purifoy, D.J.M. (1989) Infectious potential of human immunodeficiency virus type 1 reverse transcriptase mutants with altered inhibitor sensitivity. Proc. Natl Acad. Sci. USA, 86, 4803-4807.
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 4803-4807
-
-
Larder, B.A.1
Kemp, S.D.2
Purifoy, D.J.M.3
-
31
-
-
0028138893
-
Human immunodeficiency virus-1 reverse transcriptase heterodimer stability
-
Lebowitz, J., Kar, S., Braswell, E., McPherson, S. and Richard, D.L. (1994) Human immunodeficiency virus-1 reverse transcriptase heterodimer stability. Protein Sci., 3, 1374-1382.
-
(1994)
Protein Sci.
, vol.3
, pp. 1374-1382
-
-
Lebowitz, J.1
Kar, S.2
Braswell, E.3
McPherson, S.4
Richard, D.L.5
-
32
-
-
0026070438
-
Subunit-selective mutagenesis indicates minimal polymerase activity in heterodimer-associated p51 HIV-1 reverse transcriptase
-
LeGrice, S.F.J., Naas, T., Wohlgensinger, B. and Schatz, O. (1991) Subunit-selective mutagenesis indicates minimal polymerase activity in heterodimer-associated p51 HIV-1 reverse transcriptase. EMBO J., 10, 3905-3911.
-
(1991)
EMBO J.
, vol.10
, pp. 3905-3911
-
-
LeGrice, S.F.J.1
Naas, T.2
Wohlgensinger, B.3
Schatz, O.4
-
33
-
-
0025731752
-
Mutational analysis of two conserved sequence motifs in HIV-1 reverse transcriptase
-
Lowe, D.M., Parmar, V., Kemp, S.D. and Larder, B.A. (1991) Mutational analysis of two conserved sequence motifs in HIV-1 reverse transcriptase. FEBS Lett., 282, 231-234.
-
(1991)
FEBS Lett.
, vol.282
, pp. 231-234
-
-
Lowe, D.M.1
Parmar, V.2
Kemp, S.D.3
Larder, B.A.4
-
34
-
-
0027511418
-
Biochemical analysis of human immunodeficiency virus-1 reverse transcriptase containing a mutation at position lysine 263
-
Martin, J.L., Wilson, J.E., Furfine, E.S., Hopkins, S.E. and Furman, P.A. (1993a) Biochemical analysis of human immunodeficiency virus-1 reverse transcriptase containing a mutation at position lysine 263. J. Biol. Chem., 268, 2565-2570.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 2565-2570
-
-
Martin, J.L.1
Wilson, J.E.2
Furfine, E.S.3
Hopkins, S.E.4
Furman, P.A.5
-
35
-
-
0027162732
-
Mechanism of resistance of human immunodeficiency virus type 1 to 2′,3′-dideoxyinosine
-
Martin, J.L., Wilson, J.E., Haynes, R.L. and Furman, P.A. (1993b) Mechanism of resistance of human immunodeficiency virus type 1 to 2′,3′-dideoxyinosine. Proc. Natl Acad. Sci. USA, 90, 6135-6139.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 6135-6139
-
-
Martin, J.L.1
Wilson, J.E.2
Haynes, R.L.3
Furman, P.A.4
-
36
-
-
0028855166
-
Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance
-
Mellors, J.W., Larder, B.A. and Schinazi, R.F. (1995) Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance. Int. Antivir. News, 3, 8-13.
-
(1995)
Int. Antivir. News
, vol.3
, pp. 8-13
-
-
Mellors, J.W.1
Larder, B.A.2
Schinazi, R.F.3
-
37
-
-
0028783906
-
Mutational analysis of the substrate binding pocket of murine leukemia virus protease and comparison with human immunodeficiency virus proteases
-
Menéndez-Arias, L., Weber, I.T. and Oroszlan, S. (1995) Mutational analysis of the substrate binding pocket of murine leukemia virus protease and comparison with human immunodeficiency virus proteases. J. Biol. Chem., 270, 29162-29168.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 29162-29168
-
-
Menéndez-Arias, L.1
Weber, I.T.2
Oroszlan, S.3
-
38
-
-
0003518435
-
-
Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM
-
Myers, G.M., Korber, B., Hahn, B.H., Jeang, K.-T., Mellors, J.W., McCutchan, F.C. Henderson, L.E. and Pavlakis, G.N. (1995) Human Retroviruses and AIDS 1995: A Compilation and Analysis of Nucleic Acid and Amino Acid Sequences. Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, NM.
-
(1995)
Human Retroviruses and AIDS 1995: A Compilation and Analysis of Nucleic Acid and Amino Acid Sequences
-
-
Myers, G.M.1
Korber, B.2
Hahn, B.H.3
Jeang, K.-T.4
Mellors, J.W.5
McCutchan, F.C.6
Henderson, L.E.7
Pavlakis, G.N.8
-
39
-
-
0024358769
-
Co-expression of the subunits of the heterodimer of HIV-1 reverse transcriptase in Escherichia coli
-
Müller, B., Restle, T., Weiss, S., Gautel, M., Sczakiel, G. and Goody, R.S. (1989) Co-expression of the subunits of the heterodimer of HIV-1 reverse transcriptase in Escherichia coli. J. Biol. Chem., 264, 13975-13978.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 13975-13978
-
-
Müller, B.1
Restle, T.2
Weiss, S.3
Gautel, M.4
Sczakiel, G.5
Goody, R.S.6
-
40
-
-
0028988479
-
pol gene quasispecies of human immunodeficiency virus: Mutations associated with drug resistance in virus from patients undergoing no drug therapy
-
Nájera, I., Holguín, A., Quiñones-Mateu, M.E., Muñoz-Fernández, M.A., Nájera, R., López-Galíndez, C. and Domingo, E. (1995) pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy. J. Virol., 69, 23-31.
-
(1995)
J. Virol.
, vol.69
, pp. 23-31
-
-
Nájera, I.1
Holguín, A.2
Quiñones-Mateu, M.E.3
Muñoz-Fernández, M.A.4
Nájera, R.5
López-Galíndez, C.6
Domingo, E.7
-
41
-
-
0030060362
-
Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis
-
Pandey, V.N., Kaushik, N., Rege, N., Sarafianos, S.G., Yadav, P.N.S. and Modak, M.J. (1996) Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis. Biochemistry, 35, 2168-2179.
-
(1996)
Biochemistry
, vol.35
, pp. 2168-2179
-
-
Pandey, V.N.1
Kaushik, N.2
Rege, N.3
Sarafianos, S.G.4
Yadav, P.N.S.5
Modak, M.J.6
-
42
-
-
0029052967
-
Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase
-
Patel, P.H., Jacobo-Molina, A., Ding, J., Tantillo, C., Clark, A.D.,Jr, Raag, R., Nanni, R.G., Hughes, S.H. and Arnold, E. (1995) Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase. Biochemistry, 34, 5351-5363.
-
(1995)
Biochemistry
, vol.34
, pp. 5351-5363
-
-
Patel, P.H.1
Jacobo-Molina, A.2
Ding, J.3
Tantillo, C.4
Clark Jr., A.D.5
Raag, R.6
Nanni, R.G.7
Hughes, S.H.8
Arnold, E.9
-
43
-
-
0024853870
-
Extension of mismatched 3′ termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase
-
Perrino, F.W., Preston, B.D., Sandell, L.L. and Loeb, L.A. (1989) Extension of mismatched 3′ termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase. Proc. Natl Acad. Sci. USA, 86, 8343-8347.
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 8343-8347
-
-
Perrino, F.W.1
Preston, B.D.2
Sandell, L.L.3
Loeb, L.A.4
-
44
-
-
0024784519
-
Identification of four conserved motifs among the RNA-dependent polymerase encoding elements
-
Poch, O., Sauvaget, I., Delarue, M. and Tordo, N. (1989) Identification of four conserved motifs among the RNA-dependent polymerase encoding elements. EMBO J., 8, 3867-3874.
-
(1989)
EMBO J.
, vol.8
, pp. 3867-3874
-
-
Poch, O.1
Sauvaget, I.2
Delarue, M.3
Tordo, N.4
-
45
-
-
0024267430
-
Fidelity of HIV-1 reverse transcriptase
-
Preston, B.D., Poiesz, B.J. and Loeb, L.A. (1988) Fidelity of HIV-1 reverse transcriptase. Science, 242, 1168-1171.
-
(1988)
Science
, vol.242
, pp. 1168-1171
-
-
Preston, B.D.1
Poiesz, B.J.2
Loeb, L.A.3
-
46
-
-
0021912920
-
Complete nucleotide sequence of the AIDS virus, HTLV-III
-
Ratner, L. et al. (1985) Complete nucleotide sequence of the AIDS virus, HTLV-III. Nature, 313, 277-284.
-
(1985)
Nature
, vol.313
, pp. 277-284
-
-
Ratner, L.1
-
47
-
-
0025222838
-
Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5′-triphosphate and 3′-azido-3′-deoxythymidine 5′-triphosphate
-
Reardon, J.E. and Miller, W.H. (1990) Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5′-triphosphate and 3′-azido-3′-deoxythymidine 5′-triphosphate. J. Biol. Chem., 265, 20302-20307.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 20302-20307
-
-
Reardon, J.E.1
Miller, W.H.2
-
48
-
-
0025785370
-
Human immunodeficiency virus reverse transcriptase. Effect of primer length on template-primer binding
-
Reardon, J.E., Furfine, E.S. and Cheng, N. (1991) Human immunodeficiency virus reverse transcriptase. Effect of primer length on template-primer binding. J. Biol. Chem., 266, 14128-14134.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 14128-14134
-
-
Reardon, J.E.1
Furfine, E.S.2
Cheng, N.3
-
49
-
-
0029645409
-
The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: Lessons from inhibitor design
-
Ren, J.S., Esnouf, R., Hopkins, A., Ross, C., Jones, Y., Stammers, D. and Stuart, D. (1995) The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons from inhibitor design. Structure, 3, 915-926.
-
(1995)
Structure
, vol.3
, pp. 915-926
-
-
Ren, J.S.1
Esnouf, R.2
Hopkins, A.3
Ross, C.4
Jones, Y.5
Stammers, D.6
Stuart, D.7
-
50
-
-
0025215849
-
Reverse transcriptases and genomic variability: The accuracy of DNA replication is enzyme specific and sequence dependent
-
Ricchetti, M. and Buc, H. (1990) Reverse transcriptases and genomic variability: the accuracy of DNA replication is enzyme specific and sequence dependent. EMBO J., 9, 1583-1593.
-
(1990)
EMBO J.
, vol.9
, pp. 1583-1593
-
-
Ricchetti, M.1
Buc, H.2
-
51
-
-
0027475412
-
E. coli DNA polymerase I as a reverse transcriptase
-
Ricchetti, M. and Buc, H. (1993) E. coli DNA polymerase I as a reverse transcriptase. EMBO J., 12, 387-396.
-
(1993)
EMBO J.
, vol.12
, pp. 387-396
-
-
Ricchetti, M.1
Buc, H.2
-
52
-
-
0027278781
-
Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents
-
Richman, D.D. (1993) Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents. Antimicrob. Agents Chemother., 37, 1207-1213.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 1207-1213
-
-
Richman, D.D.1
-
53
-
-
0024273119
-
The accuracy of reverse transcriptase from HIV-1
-
Roberts, J.D., Bebenek, K. and Kunkel, T.A. (1988) The accuracy of reverse transcriptase from HIV-1. Science, 242, 1171-1173.
-
(1988)
Science
, vol.242
, pp. 1171-1173
-
-
Roberts, J.D.1
Bebenek, K.2
Kunkel, T.A.3
-
54
-
-
0028842293
-
The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1
-
Rodgers, D.W., Gamblin, S.J., Harris, B.A., Ray, S., Culp, J.S., Hellmig, B., Woolf, D.J., Debouck, C. and Harrison, S.C. (1995) The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1. Proc. Natl Acad. Sci. USA, 92, 1222-1226.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 1222-1226
-
-
Rodgers, D.W.1
Gamblin, S.J.2
Harris, B.A.3
Ray, S.4
Culp, J.S.5
Hellmig, B.6
Woolf, D.J.7
Debouck, C.8
Harrison, S.C.9
-
55
-
-
0029114213
-
tG:T mispair formation on RNA and DNA templates with mismatched primers: A kinetic and thermodynamic study
-
tG:T mispair formation on RNA and DNA templates with mismatched primers: a kinetic and thermodynamic study. EMBO J., 14, 4622-4627.
-
(1995)
EMBO J.
, vol.14
, pp. 4622-4627
-
-
Sala, M.1
Wain-Hobson, S.2
Schaeffer, F.3
-
56
-
-
0029112612
-
Site-directed mutagenesis of arginine 72 of HIV-1 reverse transcriptase. Catalytic role and inhibitor sensitivity
-
Sarafianos, S.G., Pandey, V.N., Kaushik, N. and Modak, M.J. (1995a) Site-directed mutagenesis of arginine 72 of HIV-1 reverse transcriptase. Catalytic role and inhibitor sensitivity. J. Biol. Chem., 270, 19729-19735.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19729-19735
-
-
Sarafianos, S.G.1
Pandey, V.N.2
Kaushik, N.3
Modak, M.J.4
-
57
-
-
0029038744
-
Glutamine 151 participates in the substrate dNTP binding function of HIV-1 reverse transcriptase
-
Sarafianos, S.G., Pandey, V.N., Kaushik, N. and Modak, M.J. (1995b) Glutamine 151 participates in the substrate dNTP binding function of HIV-1 reverse transcriptase. Biochemistry, 34, 7207-7216.
-
(1995)
Biochemistry
, vol.34
, pp. 7207-7216
-
-
Sarafianos, S.G.1
Pandey, V.N.2
Kaushik, N.3
Modak, M.J.4
-
58
-
-
0028172345
-
Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance
-
Tantillo, C. et al. (1994) Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance. J. Mol. Biol., 243, 369-387.
-
(1994)
J. Mol. Biol.
, vol.243
, pp. 369-387
-
-
Tantillo, C.1
-
59
-
-
13344294407
-
Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase
-
Wainberg, M.A. et al. (1996) Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase. Science, 271, 1282-1285.
-
(1996)
Science
, vol.271
, pp. 1282-1285
-
-
Wainberg, M.A.1
-
60
-
-
0024507160
-
Fidelity of human immunodeficiency virus type 1 reverse transcriptase in copying natural DNA
-
Weber, J. and Grosse, F. (1989) Fidelity of human immunodeficiency virus type 1 reverse transcriptase in copying natural DNA. Nucleic Acids Res., 17, 1379-1393.
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 1379-1393
-
-
Weber, J.1
Grosse, F.2
-
61
-
-
0027280807
-
Monoclonal antibody-mediated inhibition of HIV-1 reverse transcriptase polymerase activity. Interaction with a possible deoxynucleoside triphosphate binding domain
-
Wu, J., Amandoron, E., Li, X., Wainberg, M.A. and Parniak, M.A. (1993) Monoclonal antibody-mediated inhibition of HIV-1 reverse transcriptase polymerase activity. Interaction with a possible deoxynucleoside triphosphate binding domain. J. Biol. Chem., 268, 9980-9985.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 9980-9985
-
-
Wu, J.1
Amandoron, E.2
Li, X.3
Wainberg, M.A.4
Parniak, M.A.5
-
62
-
-
0026760911
-
Comparison of HIV-1 and avian myeloblastosis virus reverse transcriptase fidelity on RNA and DNA templates
-
Yu, H. and Goodman, M.F. (1992) Comparison of HIV-1 and avian myeloblastosis virus reverse transcriptase fidelity on RNA and DNA templates. J. Biol. Chem., 267, 10888-10896.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 10888-10896
-
-
Yu, H.1
Goodman, M.F.2
-
63
-
-
0028033532
-
Misincorporation and mispaired primer extension by human immunodeficiency virus reverse transcriptase
-
Zinnen, S., Hsieh, J.-C. and Modrich, P. (1994) Misincorporation and mispaired primer extension by human immunodeficiency virus reverse transcriptase. J. Biol. Chem., 269, 24195-24202.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 24195-24202
-
-
Zinnen, S.1
Hsieh, J.-C.2
Modrich, P.3
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