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Volumn 123, Issue 12, 2006, Pages 907-924

Three enhancer regions regulate gbx2 gene expression in the isthmic region during zebrafish development

Author keywords

Brain formation; DDC model; gbx2; Isthmus; Midbrain hindbrain boundary; Promoter analysis; Transcription; Zebrafish

Indexed keywords

TRANSCRIPTION FACTOR OTX2; TRANSCRIPTION FACTOR PAX2;

EID: 33751505034     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mod.2006.08.007     Document Type: Article
Times cited : (18)

References (82)
  • 1
    • 0033974766 scopus 로고    scopus 로고
    • Vertebrate evolution: recent perspectives from fish
    • Aparicio S. Vertebrate evolution: recent perspectives from fish. Trends Genet. 16 (2000) 54-56
    • (2000) Trends Genet. , vol.16 , pp. 54-56
    • Aparicio, S.1
  • 2
    • 21244491189 scopus 로고    scopus 로고
    • Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region
    • Bouchard M., Grote D., Craven S.E., Sun Q., Steinlein P., and Busslinger M. Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region. Development 132 (2005) 2633-2643
    • (2005) Development , vol.132 , pp. 2633-2643
    • Bouchard, M.1    Grote, D.2    Craven, S.E.3    Sun, Q.4    Steinlein, P.5    Busslinger, M.6
  • 3
    • 0032992524 scopus 로고    scopus 로고
    • Binding properties of the human homeodomain protein OTX2 to a DNA target sequence
    • Briata P., Ilengo C., Bobola N., and Corte G. Binding properties of the human homeodomain protein OTX2 to a DNA target sequence. FEBS Lett. 445 (1999) 160-164
    • (1999) FEBS Lett. , vol.445 , pp. 160-164
    • Briata, P.1    Ilengo, C.2    Bobola, N.3    Corte, G.4
  • 4
    • 0033539094 scopus 로고    scopus 로고
    • The caudal limit of Otx2 expression positions the isthmic organizer
    • Broccoli V., Boncinelli E., and Wurst W. The caudal limit of Otx2 expression positions the isthmic organizer. Nature 401 (1999) 164-168
    • (1999) Nature , vol.401 , pp. 164-168
    • Broccoli, V.1    Boncinelli, E.2    Wurst, W.3
  • 5
    • 0031440331 scopus 로고    scopus 로고
    • The mouse homeobox gene, Gbx2: genomic organization and expression in pluripotent cells in vitro and in vivo
    • Chapman G., Remiszewski J.L., Webb G.C., Schulz T.C., Bottema C.D.K., and Rathjen P.D. The mouse homeobox gene, Gbx2: genomic organization and expression in pluripotent cells in vitro and in vivo. Genomics 46 (1997) 223-233
    • (1997) Genomics , vol.46 , pp. 223-233
    • Chapman, G.1    Remiszewski, J.L.2    Webb, G.C.3    Schulz, T.C.4    Bottema, C.D.K.5    Rathjen, P.D.6
  • 6
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162 (1987) 156-159
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 7
    • 0029960330 scopus 로고    scopus 로고
    • Midbrain development induced by FGF8 in the chick embryo
    • Crossley P.H., Martinez S., and Martin G.R. Midbrain development induced by FGF8 in the chick embryo. Nature 380 (1996) 66-68
    • (1996) Nature , vol.380 , pp. 66-68
    • Crossley, P.H.1    Martinez, S.2    Martin, G.R.3
  • 8
    • 0027426925 scopus 로고
    • DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site
    • Czerny T., Schaffner G., and Busslinger M. DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site. Genes Dev. 7 (1993) 2048-2061
    • (1993) Genes Dev. , vol.7 , pp. 2048-2061
    • Czerny, T.1    Schaffner, G.2    Busslinger, M.3
  • 9
    • 0034652207 scopus 로고    scopus 로고
    • Efficient studies of long-distance Bmp5 gene regulation using bacterial artificial chromosomes
    • DiLeone R.J., Marcus G.A., Johnson M.D., and Kingsley D.M. Efficient studies of long-distance Bmp5 gene regulation using bacterial artificial chromosomes. Proc. Natl. Acad. Sci. USA 97 (2000) 1612-1617
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 1612-1617
    • DiLeone, R.J.1    Marcus, G.A.2    Johnson, M.D.3    Kingsley, D.M.4
  • 10
    • 0028239775 scopus 로고
    • Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes
    • Epstein J., Cai J., Glaser T., Jepeal L., and Maas R. Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes. J. Biol. Chem. 269 (1994) 8355-8361
    • (1994) J. Biol. Chem. , vol.269 , pp. 8355-8361
    • Epstein, J.1    Cai, J.2    Glaser, T.3    Jepeal, L.4    Maas, R.5
  • 11
    • 0035114788 scopus 로고    scopus 로고
    • Neuroepithelial co-expression of Gbx2 and Otx2 precedes Fgf8 expression in the isthmic organizer
    • Garda A.-L., Echevarria D., and Martinez S. Neuroepithelial co-expression of Gbx2 and Otx2 precedes Fgf8 expression in the isthmic organizer. Mech. Dev. 101 (2001) 111-118
    • (2001) Mech. Dev. , vol.101 , pp. 111-118
    • Garda, A.-L.1    Echevarria, D.2    Martinez, S.3
  • 12
    • 0036023310 scopus 로고    scopus 로고
    • The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation
    • Glavic A., Gómez-Skarmeta J.L., and Mayor R. The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation. Development 129 (2002) 1609-1621
    • (2002) Development , vol.129 , pp. 1609-1621
    • Glavic, A.1    Gómez-Skarmeta, J.L.2    Mayor, R.3
  • 14
    • 0033993891 scopus 로고    scopus 로고
    • Regulatory gene expression patterns reveal transverse and longitudinal subdivisions of the embryonic zebrafish forebrain
    • Hauptmann G., and Gerster T. Regulatory gene expression patterns reveal transverse and longitudinal subdivisions of the embryonic zebrafish forebrain. Mech. Dev. 91 (2000) 105-118
    • (2000) Mech. Dev. , vol.91 , pp. 105-118
    • Hauptmann, G.1    Gerster, T.2
  • 16
    • 0344572792 scopus 로고    scopus 로고
    • Comparative analysis of Otx2, Gbx2, Pax2, Fgf8 and Wnt1 gene expressions during the formation of the chick midbrain/hindbrain domain
    • Hidalgo-Sanchez M., Millet S., Simeone A., and Alvarado-Mallart R.-M. Comparative analysis of Otx2, Gbx2, Pax2, Fgf8 and Wnt1 gene expressions during the formation of the chick midbrain/hindbrain domain. Mech. Dev. 80 (1999) 175-178
    • (1999) Mech. Dev. , vol.80 , pp. 175-178
    • Hidalgo-Sanchez, M.1    Millet, S.2    Simeone, A.3    Alvarado-Mallart, R.-M.4
  • 17
    • 0038820118 scopus 로고    scopus 로고
    • An urbilaterian origin of the tripartite brain: developmental genetic insights from Drosophila
    • Hirth F., Kammermeier L., Frei E., Walldorf U., Noll M., and Reichert H. An urbilaterian origin of the tripartite brain: developmental genetic insights from Drosophila. Development 130 (2003) 2365-2373
    • (2003) Development , vol.130 , pp. 2365-2373
    • Hirth, F.1    Kammermeier, L.2    Frei, E.3    Walldorf, U.4    Noll, M.5    Reichert, H.6
  • 18
    • 0041570261 scopus 로고    scopus 로고
    • Characterization of the upstream region that regulates the transcription of the gene for the precursor to EGF-related peptides, exogastrula-inducing peptides, of the sea urchin Anthocidaris crassispina
    • Horii K., Suzuki G., Suyemitsu T., and Yamasu K. Characterization of the upstream region that regulates the transcription of the gene for the precursor to EGF-related peptides, exogastrula-inducing peptides, of the sea urchin Anthocidaris crassispina. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 136 (2003) 15-26
    • (2003) Comp. Biochem. Physiol. B Biochem. Mol. Biol. , vol.136 , pp. 15-26
    • Horii, K.1    Suzuki, G.2    Suyemitsu, T.3    Yamasu, K.4
  • 20
    • 0033224364 scopus 로고    scopus 로고
    • Anteroposterior patterning by mutual repression of orthodenticle and caudal-type transcription factors
    • Isaacs H.V., Andreazzoli M., and Slack J.M.W. Anteroposterior patterning by mutual repression of orthodenticle and caudal-type transcription factors. Evol. Dev. 1 (1999) 143-152
    • (1999) Evol. Dev. , vol.1 , pp. 143-152
    • Isaacs, H.V.1    Andreazzoli, M.2    Slack, J.M.W.3
  • 21
    • 0034841786 scopus 로고    scopus 로고
    • Double in situ hybridization techniques in zebrafish
    • Jowett T. Double in situ hybridization techniques in zebrafish. Methods 23 (2001) 345-358
    • (2001) Methods , vol.23 , pp. 345-358
    • Jowett, T.1
  • 23
    • 0028982107 scopus 로고
    • Involvement of Wnt1 and Pax2 in the formation of the midbrain-hindbrain boundary in the zebrafish gastrula
    • Kelly G.M., and Moon R.T. Involvement of Wnt1 and Pax2 in the formation of the midbrain-hindbrain boundary in the zebrafish gastrula. Dev. Genet. 17 (1995) 129-140
    • (1995) Dev. Genet. , vol.17 , pp. 129-140
    • Kelly, G.M.1    Moon, R.T.2
  • 24
    • 0242558206 scopus 로고    scopus 로고
    • gbx2 Homeobox gene is required for the maintenance of the isthmic region in the zebrafish embryonic brain
    • Kikuta H., Kanai M., Ito Y., and Yamasu K. gbx2 Homeobox gene is required for the maintenance of the isthmic region in the zebrafish embryonic brain. Dev. Dyn. 228 (2003) 433-450
    • (2003) Dev. Dyn. , vol.228 , pp. 433-450
    • Kikuta, H.1    Kanai, M.2    Ito, Y.3    Yamasu, K.4
  • 26
    • 0027441203 scopus 로고
    • Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties
    • Kozmik Z., Kurzbauer R., Dorfler P., and Busslinger M. Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties. Mol. Cell Biol. 13 (1993) 6024-6035
    • (1993) Mol. Cell Biol. , vol.13 , pp. 6024-6035
    • Kozmik, Z.1    Kurzbauer, R.2    Dorfler, P.3    Busslinger, M.4
  • 30
    • 0030933498 scopus 로고    scopus 로고
    • Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain
    • Lee S.M., Danielian P.S., Fritzsch B., and McMahon A.P. Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. Development 124 (1997) 959-969
    • (1997) Development , vol.124 , pp. 959-969
    • Lee, S.M.1    Danielian, P.S.2    Fritzsch, B.3    McMahon, A.P.4
  • 31
    • 0037443114 scopus 로고    scopus 로고
    • wnt1 and wnt10b function redundantly at the zebrafish midbrain-hindbrain boundary
    • Lekven A.C., Buckles G.R., Kostakis N., and Moon R.T. wnt1 and wnt10b function redundantly at the zebrafish midbrain-hindbrain boundary. Dev. Biol. 254 (2003) 172-187
    • (2003) Dev. Biol. , vol.254 , pp. 172-187
    • Lekven, A.C.1    Buckles, G.R.2    Kostakis, N.3    Moon, R.T.4
  • 32
    • 0032567339 scopus 로고    scopus 로고
    • Generation of destabilized green fluorescent protein as a transcription reporter
    • Li X., Zhao X., Fang Y., Jiang X., Duong T., Fan C., Huang C.C., and Kain S.R. Generation of destabilized green fluorescent protein as a transcription reporter. J. Biol. Chem. 273 (1998) 34970-34975
    • (1998) J. Biol. Chem. , vol.273 , pp. 34970-34975
    • Li, X.1    Zhao, X.2    Fang, Y.3    Jiang, X.4    Duong, T.5    Fan, C.6    Huang, C.C.7    Kain, S.R.8
  • 34
    • 0032708854 scopus 로고    scopus 로고
    • FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate
    • Liu A., Losos K., and Joyner A.L. FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate. Development 126 (1999) 4827-4838
    • (1999) Development , vol.126 , pp. 4827-4838
    • Liu, A.1    Losos, K.2    Joyner, A.L.3
  • 35
    • 0031667842 scopus 로고    scopus 로고
    • A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain-hindbrain boundary
    • Lun K., and Brand M. A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain-hindbrain boundary. Development 125 (1998) 3049-3062
    • (1998) Development , vol.125 , pp. 3049-3062
    • Lun, K.1    Brand, M.2
  • 36
    • 0025823977 scopus 로고
    • Induction of a mesencephalic phenotype in the 2-day-old chick prosencephalon is preceded by the early expression of the homeobox gene en
    • Martinez S., Wassef M., and Alvarado-Mallart R.M. Induction of a mesencephalic phenotype in the 2-day-old chick prosencephalon is preceded by the early expression of the homeobox gene en. Neuron 6 (1991) 971-981
    • (1991) Neuron , vol.6 , pp. 971-981
    • Martinez, S.1    Wassef, M.2    Alvarado-Mallart, R.M.3
  • 37
    • 0029063521 scopus 로고
    • Induction of ectopic engrailed expression and fate change in avian rhombomeres: intersegmental boundaries as barriers
    • Martinez S., Marin F., Nieto M.A., and Puelles L. Induction of ectopic engrailed expression and fate change in avian rhombomeres: intersegmental boundaries as barriers. Mech. Dev. 51 (1995) 289-303
    • (1995) Mech. Dev. , vol.51 , pp. 289-303
    • Martinez, S.1    Marin, F.2    Nieto, M.A.3    Puelles, L.4
  • 38
    • 0035207512 scopus 로고    scopus 로고
    • Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2
    • Martinez-Barbera J.P., Signore M., Boyl P.P., Puelles E., Acampora D., Gogoi R., Schubert F., Lumsden A., and Simeone A. Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2. Development 128 (2001) 4789-4800
    • (2001) Development , vol.128 , pp. 4789-4800
    • Martinez-Barbera, J.P.1    Signore, M.2    Boyl, P.P.3    Puelles, E.4    Acampora, D.5    Gogoi, R.6    Schubert, F.7    Lumsden, A.8    Simeone, A.9
  • 39
    • 0036670056 scopus 로고    scopus 로고
    • FGF3 and FGF8 mediate a rhombomere 4 signaling activity in the zebrafish hindbrain
    • Maves L., Jackman W., and Kimmel C.B. FGF3 and FGF8 mediate a rhombomere 4 signaling activity in the zebrafish hindbrain. Development 129 (2002) 3825-3837
    • (2002) Development , vol.129 , pp. 3825-3837
    • Maves, L.1    Jackman, W.2    Kimmel, C.B.3
  • 40
    • 0032779946 scopus 로고    scopus 로고
    • An octamer-binding site is crucial for the activity of an enhancer active at the embryonic met-/mesencephalic junction
    • Mihailescu D., Kury P., and Monard D. An octamer-binding site is crucial for the activity of an enhancer active at the embryonic met-/mesencephalic junction. Mech. Dev. 84 (1999) 55-67
    • (1999) Mech. Dev. , vol.84 , pp. 55-67
    • Mihailescu, D.1    Kury, P.2    Monard, D.3
  • 41
    • 0033539146 scopus 로고    scopus 로고
    • A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer
    • Millet S., Campbell K., Epstein D.J., Losos K., Harris E., and Joyner A.L. A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer. Nature 401 (1999) 161-164
    • (1999) Nature , vol.401 , pp. 161-164
    • Millet, S.1    Campbell, K.2    Epstein, D.J.3    Losos, K.4    Harris, E.5    Joyner, A.L.6
  • 42
    • 0033166974 scopus 로고    scopus 로고
    • A conserved 30 base pair element in the Wnt-5a promoter is sufficient both to drive its' early embryonic expression and to mediate its' repression by otx2
    • Morgan R., Hooiveld M.H.W., In der Rieden P., and Durston A.J. A conserved 30 base pair element in the Wnt-5a promoter is sufficient both to drive its' early embryonic expression and to mediate its' repression by otx2. Mech. Dev. 85 (1999) 97-102
    • (1999) Mech. Dev. , vol.85 , pp. 97-102
    • Morgan, R.1    Hooiveld, M.H.W.2    In der Rieden, P.3    Durston, A.J.4
  • 43
    • 0028079922 scopus 로고
    • Differential spatio-temporal expressions of three otx homeoprotein transcripts during zebrafish embryogenesis
    • Mori H., Miyazaki Y., Morita T., Nitta H., and Mishina M. Differential spatio-temporal expressions of three otx homeoprotein transcripts during zebrafish embryogenesis. Brain Res. Mol. Brain Res. 27 (1994) 221-231
    • (1994) Brain Res. Mol. Brain Res. , vol.27 , pp. 221-231
    • Mori, H.1    Miyazaki, Y.2    Morita, T.3    Nitta, H.4    Mishina, M.5
  • 44
    • 0344171940 scopus 로고    scopus 로고
    • Intronic enhancers control expression of zebrafish sonic hedgehog in floor plate and notochord
    • Muller F., Chang B.-E., Albert S., Fischer N., Tora L., and Strahle U. Intronic enhancers control expression of zebrafish sonic hedgehog in floor plate and notochord. Development 126 (1999) 2103-2116
    • (1999) Development , vol.126 , pp. 2103-2116
    • Muller, F.1    Chang, B.-E.2    Albert, S.3    Fischer, N.4    Tora, L.5    Strahle, U.6
  • 45
    • 1842374429 scopus 로고    scopus 로고
    • Activator effect of coinjected enhancers on the muscle-specific expression of promoters in zebrafish embryos
    • Muller F., Williams D.W., Kobolak J., Gauvry L., Goldspink G., Orban L., and Maclean N. Activator effect of coinjected enhancers on the muscle-specific expression of promoters in zebrafish embryos. Mol. Reprod. Dev. 47 (1997) 404-412
    • (1997) Mol. Reprod. Dev. , vol.47 , pp. 404-412
    • Muller, F.1    Williams, D.W.2    Kobolak, J.3    Gauvry, L.4    Goldspink, G.5    Orban, L.6    Maclean, N.7
  • 46
    • 0030716471 scopus 로고    scopus 로고
    • Comparable rates of gene loss and functional divergence after genome duplications early in vertebrate evolution
    • Nadeau J.H., and Sankoff D. Comparable rates of gene loss and functional divergence after genome duplications early in vertebrate evolution. Genetics 147 (1997) 1259-1266
    • (1997) Genetics , vol.147 , pp. 1259-1266
    • Nadeau, J.H.1    Sankoff, D.2
  • 47
    • 0022884860 scopus 로고
    • Plasticity and rigidity of differentiation of brain vesicles studied in quail-chick chimeras
    • Nakamura H., Nakano K.E., Igawa H.H., Takagi S., and Fujisawa H. Plasticity and rigidity of differentiation of brain vesicles studied in quail-chick chimeras. Cell Differ. 19 (1986) 187-193
    • (1986) Cell Differ. , vol.19 , pp. 187-193
    • Nakamura, H.1    Nakano, K.E.2    Igawa, H.H.3    Takagi, S.4    Fujisawa, H.5
  • 49
    • 0032144211 scopus 로고    scopus 로고
    • Expression of the homeobox gene GBX2 during chicken development
    • Niss K., and Leutz A. Expression of the homeobox gene GBX2 during chicken development. Mech. Dev. 76 (1998) 151-155
    • (1998) Mech. Dev. , vol.76 , pp. 151-155
    • Niss, K.1    Leutz, A.2
  • 51
    • 0032773909 scopus 로고    scopus 로고
    • Roles of Pax-2 in initiation of the chick tectal development
    • Okafuji T., Funahashi J., and Nakamura H. Roles of Pax-2 in initiation of the chick tectal development. Brain Res. Dev. Brain Res. 116 (1999) 41-49
    • (1999) Brain Res. Dev. Brain Res. , vol.116 , pp. 41-49
    • Okafuji, T.1    Funahashi, J.2    Nakamura, H.3
  • 52
    • 0034023062 scopus 로고    scopus 로고
    • Pax2 and homeodomain proteins cooperatively regulate a 435 bp enhancer of the mouse Pax5 gene at the midbrain-hindbrain boundary
    • Pfeffer P.L., Bouchard M., and Busslinger M. Pax2 and homeodomain proteins cooperatively regulate a 435 bp enhancer of the mouse Pax5 gene at the midbrain-hindbrain boundary. Development 127 (2000) 1017-1028
    • (2000) Development , vol.127 , pp. 1017-1028
    • Pfeffer, P.L.1    Bouchard, M.2    Busslinger, M.3
  • 53
    • 0031668375 scopus 로고    scopus 로고
    • Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function
    • Pfeffer P.L., Gerster T., Lun K., Brand M., and Busslinger M. Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function. Development 125 (1998) 3063-3074
    • (1998) Development , vol.125 , pp. 3063-3074
    • Pfeffer, P.L.1    Gerster, T.2    Lun, K.3    Brand, M.4    Busslinger, M.5
  • 54
    • 0036337473 scopus 로고    scopus 로고
    • The activation and maintenance of Pax2 expression at the mid-hindbrain boundary is controlled by separate enhancers
    • Pfeffer P.L., Payer B., Reim G., di Magliano M.P., and Busslinger M. The activation and maintenance of Pax2 expression at the mid-hindbrain boundary is controlled by separate enhancers. Development 129 (2002) 307-318
    • (2002) Development , vol.129 , pp. 307-318
    • Pfeffer, P.L.1    Payer, B.2    Reim, G.3    di Magliano, M.P.4    Busslinger, M.5
  • 55
    • 0036333606 scopus 로고    scopus 로고
    • A novel positive transcriptional feedback loop in midbrain-hindbrain boundary development is revealed through analysis of the zebrafish pax2.1 promoter in transgenic lines
    • Picker A., Scholpp S., Bohli H., Takeda H., and Brand M. A novel positive transcriptional feedback loop in midbrain-hindbrain boundary development is revealed through analysis of the zebrafish pax2.1 promoter in transgenic lines. Development 129 (2002) 3227-3239
    • (2002) Development , vol.129 , pp. 3227-3239
    • Picker, A.1    Scholpp, S.2    Bohli, H.3    Takeda, H.4    Brand, M.5
  • 56
    • 0036845822 scopus 로고    scopus 로고
    • Splitting pairs: the diverging fates of duplicated genes
    • Prince V.E., and Pickett F.B. Splitting pairs: the diverging fates of duplicated genes. Nat. Rev. Genet. 3 (2002) 827-837
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 827-837
    • Prince, V.E.1    Pickett, F.B.2
  • 57
    • 0036333254 scopus 로고    scopus 로고
    • spiel-ohne-grenzen/pou2 mediates regional competence to respond to Fgf8 during zebrafish early neural development
    • Reim G., and Brand M. spiel-ohne-grenzen/pou2 mediates regional competence to respond to Fgf8 during zebrafish early neural development. Development 129 (2002) 917-933
    • (2002) Development , vol.129 , pp. 917-933
    • Reim, G.1    Brand, M.2
  • 58
    • 0035252737 scopus 로고    scopus 로고
    • The midbrain-hindbrain boundary organizer
    • Rhinn M., and Brand M. The midbrain-hindbrain boundary organizer. Curr. Opin. Neurobiol. 11 (2001) 34-42
    • (2001) Curr. Opin. Neurobiol. , vol.11 , pp. 34-42
    • Rhinn, M.1    Brand, M.2
  • 59
    • 0042831172 scopus 로고    scopus 로고
    • Cloning, expression and relationship of zebrafish gbx1 and gbx2 genes to Fgf signaling
    • Rhinn M., Lun K., Amores A., Yan Y.-L., Postlethwait J.H., and Brand M. Cloning, expression and relationship of zebrafish gbx1 and gbx2 genes to Fgf signaling. Mech. Dev. 120 (2003) 919-936
    • (2003) Mech. Dev. , vol.120 , pp. 919-936
    • Rhinn, M.1    Lun, K.2    Amores, A.3    Yan, Y.-L.4    Postlethwait, J.H.5    Brand, M.6
  • 60
    • 0942287277 scopus 로고    scopus 로고
    • Isolation and expression of the homeobox gene Gbx1 during mouse development
    • Rhinn M., Lun K., Werner M., Simeone A., and Brand M. Isolation and expression of the homeobox gene Gbx1 during mouse development. Dev. Dyn. 229 (2004) 334-339
    • (2004) Dev. Dyn. , vol.229 , pp. 334-339
    • Rhinn, M.1    Lun, K.2    Werner, M.3    Simeone, A.4    Brand, M.5
  • 61
    • 0031858210 scopus 로고    scopus 로고
    • Identification of an evolutionarily conserved 110 base-pair cis-acting regulatory sequence that governs Wnt-1 expression in the murine neural plate
    • Rowitch D.H., Echelard Y., Danielian P.S., Gellner K., Brenner S., and McMahon A.P. Identification of an evolutionarily conserved 110 base-pair cis-acting regulatory sequence that governs Wnt-1 expression in the murine neural plate. Development 125 (1998) 2735-2746
    • (1998) Development , vol.125 , pp. 2735-2746
    • Rowitch, D.H.1    Echelard, Y.2    Danielian, P.S.3    Gellner, K.4    Brenner, S.5    McMahon, A.P.6
  • 62
    • 0029125995 scopus 로고
    • Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1
    • Rowitch D.H., and McMahon A.P. Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1. Mech. Dev. 52 (1995) 3-8
    • (1995) Mech. Dev. , vol.52 , pp. 3-8
    • Rowitch, D.H.1    McMahon, A.P.2
  • 65
    • 0034919848 scopus 로고    scopus 로고
    • Inductive signal and tissue responsiveness defining the tectum and the cerebellum
    • Sato T., Araki I., and Nakamura H. Inductive signal and tissue responsiveness defining the tectum and the cerebellum. Development 128 (2001) 2461-2469
    • (2001) Development , vol.128 , pp. 2461-2469
    • Sato, T.1    Araki, I.2    Nakamura, H.3
  • 66
    • 4644252454 scopus 로고    scopus 로고
    • The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway
    • Sato T., and Nakamura H. The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway. Development 131 (2004) 4275-4285
    • (2004) Development , vol.131 , pp. 4275-4285
    • Sato, T.1    Nakamura, H.2
  • 68
    • 0032143609 scopus 로고    scopus 로고
    • Expression of Gbx-2 during early development of the chick embryo
    • Shamim H., and Mason I. Expression of Gbx-2 during early development of the chick embryo. Mech. Dev. 76 (1998) 157-159
    • (1998) Mech. Dev. , vol.76 , pp. 157-159
    • Shamim, H.1    Mason, I.2
  • 69
    • 0034214298 scopus 로고    scopus 로고
    • Positioning the isthmic organizer where Otx2 and Gbx2 meet
    • Simeone A. Positioning the isthmic organizer where Otx2 and Gbx2 meet. Trends Genet. 16 (2000) 237-240
    • (2000) Trends Genet. , vol.16 , pp. 237-240
    • Simeone, A.1
  • 71
    • 0030039249 scopus 로고    scopus 로고
    • Two Pax-binding sites are required for early embryonic brain expression of an Engrailed-2 transgene
    • Song D.-L., Chalepakis G., Gruss P., and Joyner A.L. Two Pax-binding sites are required for early embryonic brain expression of an Engrailed-2 transgene. Development 122 (1996) 627-635
    • (1996) Development , vol.122 , pp. 627-635
    • Song, D.-L.1    Chalepakis, G.2    Gruss, P.3    Joyner, A.L.4
  • 72
    • 0033987611 scopus 로고    scopus 로고
    • Two Pax2/5/8-binding sites in Engrailed2 are required for proper initiation of endogenous mid-hindbrain expression
    • Song D.L., and Joyner A.L. Two Pax2/5/8-binding sites in Engrailed2 are required for proper initiation of endogenous mid-hindbrain expression. Mech. Dev. 90 (2000) 155-165
    • (2000) Mech. Dev. , vol.90 , pp. 155-165
    • Song, D.L.1    Joyner, A.L.2
  • 73
    • 0023884698 scopus 로고
    • Replication, integration and stable germ-line transmission of foreign sequences injected into early zebrafish embryos
    • Stuart G.W., McMurray J.V., and Westerfield M. Replication, integration and stable germ-line transmission of foreign sequences injected into early zebrafish embryos. Development 103 (1988) 403-412
    • (1988) Development , vol.103 , pp. 403-412
    • Stuart, G.W.1    McMurray, J.V.2    Westerfield, M.3
  • 74
    • 0036126119 scopus 로고    scopus 로고
    • The expression of gbx-2 during zebrafish embryogenesis
    • Su Y., and Meng A. The expression of gbx-2 during zebrafish embryogenesis. Mech. Dev. 113 (2002) 107-110
    • (2002) Mech. Dev. , vol.113 , pp. 107-110
    • Su, Y.1    Meng, A.2
  • 75
    • 13944280317 scopus 로고    scopus 로고
    • Regulation of isthmic Fgf8 signal by sprouty
    • Suzuki-Hirano A., Sato T., and Nakamura H. Regulation of isthmic Fgf8 signal by sprouty. Development 132 (2005) 257-265
    • (2005) Development , vol.132 , pp. 257-265
    • Suzuki-Hirano, A.1    Sato, T.2    Nakamura, H.3
  • 76
    • 0025074908 scopus 로고
    • Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development
    • Thomas K.R., and Capecchi M.R. Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature 346 (1990) 847-850
    • (1990) Nature , vol.346 , pp. 847-850
    • Thomas, K.R.1    Capecchi, M.R.2
  • 77
    • 0030044047 scopus 로고    scopus 로고
    • The Xenopus laevis homeobox gene Xgbx-2 is an early marker of anteroposterior patterning in the ectoderm
    • von Bubnoff A., Schmidt J.E., and Kimelman D. The Xenopus laevis homeobox gene Xgbx-2 is an early marker of anteroposterior patterning in the ectoderm. Mech. Dev. 54 (1996) 149-160
    • (1996) Mech. Dev. , vol.54 , pp. 149-160
    • von Bubnoff, A.1    Schmidt, J.E.2    Kimelman, D.3
  • 79
    • 0030851192 scopus 로고    scopus 로고
    • Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function
    • Wassarman K.M., Lewandoski M., Campbell K., Joyner A.L., Rubenstein J.L.R., Martinez S., and Martin G.R. Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. Development 124 (1997) 2923-2934
    • (1997) Development , vol.124 , pp. 2923-2934
    • Wassarman, K.M.1    Lewandoski, M.2    Campbell, K.3    Joyner, A.L.4    Rubenstein, J.L.R.5    Martinez, S.6    Martin, G.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.