Characterization and sequence analysis of the human homeobox-containing gene GBX2

Genomics

Volumn 31, Issue 3, 1996, Pages 335-342

  Lin, Xu ^a   Swaroop, Anand ^b   Vaccarino, Flora M ^a   Murtha, Michael T ^c   Haas, Melanie ^a   Ji, Xiaodong ^b   Ruddle, Frank H ^a   Leckman, James F ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c Cura Gene Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; HOMEODOMAIN PROTEIN; POLYADENYLATED RNA; PROLINE; TRINUCLEOTIDE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CHROMOSOME 2Q; EMBRYO; FETUS; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; HOMEOBOX; HUMAN; HUMAN CELL; HUMAN TISSUE; HYBRID CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT;

ANIMALIA; GALLUS GALLUS;

EID: 0030044841     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1996.0056     Document Type: Article

References (38)

1. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K., Eds. (1989). "Current Protocols in Molecular Biology and Supplements," Wiley, New York.
2. Bulfone, A., Puelles, L., Porteus, M. H., Frohman, M. A., Martin, G. R., and Rubenstein, J. L. R. (1993). Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2 and Wnt-3 in embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. J. Neurosci. 13: 3155-3172.
3. Cannizzaro, L. A., Croce, C. M., Griffin, C. A., Simeone, A., Boncinelli, E., and Huebner, K. (1987). Human homeo box-containing genes located at chromosome regions 2q31-2q37 and 12q12-12q13. Am. J. Hum. Genet. 41: 1-15.
4. Caskey, C. T., Pizzuti, A., Fu, Y. H., Fenwick, R. G., Jr., and Nelson, D. L. (1992). Triplet repeat mutations in human disease. Science 256: 784-789.
5. Chapman, G., and Rathjen, P. D. (1995). Sequence and evolutionary conservation of murine Gbx-2 homeobox gene. FEBS Lett. 364: 289-292.
6. Fainsod, A., and Gruenbaum, Y. (1989). A chicken homeo box gene with developmentally regulated expression. FEBS Lett. 250: 381-385.
7. Frohman, M. A., Dickinson, M. E., Hogan, B. L. M., and Martin, G. R. (1993). Mapping of Gbx-1 to mouse chromosome 5 and Gbx-2 to mouse chromosome 1. Mouse Genome 91: 323-325.
8. Gehring, W. J. (1987). Homeo boxes in the study of development. Science 236: 1245-1252.
9. Haas, M., Aburatani, H., Stanton, V. P., Bhatt, M., Housman, D., and Ward, D. (1993). Isolation and FISH mapping of 80 cosmid clones on the short arm of human chromosome 3. Genomics 16: 90-96.
10. Holland, P. W. H., and Hogan, B. L. M. (1988). Expression of homeo box genes during mouse development: A review. Genes Dev. 2: 773-782.
11. Huntington's Disease Collaborative Research Group (1993). A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72: 971-983.
12. Leckman, J. F. (1991). Genes and the genesis of the CNS: Hints from the homeobox. J. Child Adolesc. Psychopharmacol. 3: 207-211.
13. Lichter, P., Tang, C. C., Call, K., Hermanson, G., Evans, G. A., Housman, D., and Ward, D. (1990). High resolution mapping of human chromosome 11 by in situ hybridization with cosmid clones. Science 247: 11-32.
14. Lu, S., Bogarad, L. D., Murtha, M. T., and Ruddle, F. H. (1992). Expression pattern of a murine homeobox gene, Dbx, displays extreme spatial restriction in embryonic forebrain and spinal cord. Proc. Natl. Acad. Sci. USA 89: 8053-8057.
15. Matera, G., and Ward, D. (1990). Oligonucleotide probes for the analysis of specific repetitive DNA sequences by fluorescent in situ hybridization. Hum. Mol. Genet. 1: 535-539.
16. Matsui, T., Hirai, M., Hirano, M., and Kurosawa, Y. (1993a). The HOX complex neighbored by the EVX gene, as well as two other homeobox-containing genes, the GBX-class and the EN-class, are located on the same chromosomes 2 and 7 in humans. FEBS Lett. 336: 107-110.
17. Matsui, T., Hirai, M., Wakita, M., Hirano, M., and Kurosawa, Y. (1993b). Expression of a novel human homeobox-containing gene that maps to chromosome 7q36.1 in hematopoietic cells. FEBS Lett. 322: 181-185.
18. Mavilio, F., Simeone, A., Giampaolo, A., Fiaella, A., Zappavigna, V., Acampora, D., Poiana, G., Russo, G., Peschle, C., and Boncinelli, E. (1986). Differential and stage-related expression in embryonic tissues of a new human homeobox gene. Nature 324: 664-668.
19. McGinnis, W., Levine, M. S., Hafen, E., Kuroiwa, A., and Gehring, W. J. (1984). A conserved DNA sequence in homeotic genes of the Drosophila antennapedia and bithorax complexes. Nature 308: 428-433.
20. Mermod, N., O'Neill, E. A., Kelly, T. J., and Tjian, R. (1990). The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain. Cell 58: 741-753.
21. Mitchell, P. J., and Tjian, R. (1989). Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 245: 371-378.
22. Murtha, M. T., Leckman, J. F., and Ruddle, F. H. (1991). Detection of homeobox genes in development and evolution. Proc. Natl. Acad. Sci. USA 88: 10711-10715.
23. Porteus, M. H., Bulfone, A., Ciaranello, R. D., and Rubenstein, J. L. R. (1991). Isolation and characterization of a novel cDNA clone encoding a homeodomain that is developmentally regulated in the ventral forebrain. Neuron 7: 221-229.
24. Price, M., Lemaistre, M., Pischetola, M., DiLauro, R., and Duboule, D. (1991). A mouse gene related to Distal-less shows a restricted expression in the developing forebrain. Nature 351: 748-751.
25. Puelles, L., and Rubenstein, J. L. R. (1993). Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization. Trends Neurosci. 16: 472-479.
26. Rakic, P. (1988). Specification of cerebral cortical areas. Science 241: 170-176.
27. Renucci, A., Zappavigna, V., Zàkàny, J., Izpisua-Belmonte, J. C., Bürki, K., and Duboule, D. (1992). Comparison of mouse and human HOX-4 complexes defines conserved sequences involved in the regulation of Hox-4.4. EMBO J. 11: 1459-1468.
28. Robel, L., James, A. J., Xu, L. A., Leckman, J. F., and Vaccarino, F. M. FGF2 increases the expression of the homeobox gene Otx-2 in progenitor cells from the mammalian telencephalon. J. Neurosci., in press.
29. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989). ̈Molecular Cloning: A Laboratory Manual,̈ 2nd ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
30. Scott, M. P., and Weiner, A. J. (1984). Structural relationships among genes that control development: Sequence homology between the antennapedia, ultrabithorax, and fushi tarazu loci of Drosophila. Proc. Natl. Acad. Sci. USA 81: 4115-4119.
31. Simeone, A., Acampora, D., Gulisano, M., Stornaiuolo, A., and Boncinelli, E. (1992a). Nested expression domains of four homeobox genes in developing rostral brain. Nature 358: 687-690.
32. Simeone, A., Acampora, D., Pannese, M., D'Eposito, M., Stornaiuolo, A., Gulisano, M., Mallamaci, A., Kastury, K., Druck, T., Huebner, K., and Boncinelli, E. (1994). Cloning and characterization of two members of the vertebrate Dlx gene family. Proc. Natl. Acad. Sci. USA 91: 2250-2254.
33. Simeone, A., Gulisano, M., Acampora, D., Stornaiuolo, A., Rambaldi, M., and Boncinelli, E., et al. (1992b). Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J. 11: 2541-2550.
34. Simeone, A., Mavilio, F., Acampora, D., Giampaolo, A., Fiaella, A., Zappavigna, V., D'Eposito, M., Pannese, M., Russo, G., and Boncinelli, E. (1987). Two human homeobox genes, c1 and c8: Structure analysis and expression in embryonic development. Proc. Natl. Acad. Sci. USA 84: 4914-4918.
35. Stubbs, L., Huxley, C., Hogan, B., Evans, T., Fried, M., Duboule, D., and Lehrach, H. (1990). The hox-5 and surfeit gene clusters are linked in the proximal portion of mouse chromosome 2. Genomics 6: 645-650.
36. Swaroop, A., and Weissman, S. M. (1988). Charon BS(+) and (-), versatile lambda phage vectors for constructing directional cDNA libraries and their efficient transfer to plasmids. Nucleic Acids Res. 16: 873.
37. Swaroop, A., and Xu, J. (1993). cDNA libraries from human tissues and cell lines. Cytogenet. Cell Genet. 64: 292-294.
38. Wilkinson, D. G., Bhatt, S., Cook, M., Boncinelli, E., and Krumlauf, R. (1989). Segmental expression of Hox-2 homeobox-containing genes in the developing mouse hindbrain. Nature 341: 405-409.