메뉴 건너뛰기




Volumn 84, Issue 1-2, 1999, Pages 55-67

An octamer-binding site is crucial for the activity of an enhancer active at the embryonic met-/mesencephalic junction

Author keywords

Anterior posterior axis; Brn 1; Brn 2; Brn 4; Development; DNA sequence ocular motor nerve; Electrophoretic mobility shift assay; Enhancer; Expression pattern; FGF 8; Gene expression; Gene regulation; In situ hybridization; Isthmic organizer; LacZ; Mesencephalon; Met mesencephalic junction; Metencephalon; Mouse; Nervous system; Neural tube; Oct 1; Oct 2; Oct 6; Octamer site; POU transcription factor; Promoter; Protease inhibitor; Protease Nexin 1; Segmental border; Serine protease; Transcriptional regulation; Transfection; Transgenic mice

Indexed keywords

BETA GALACTOSIDASE; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 8; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 0032779946     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(99)00067-2     Document Type: Article
Times cited : (12)

References (45)
  • 1
    • 0030730823 scopus 로고    scopus 로고
    • Genetic control of brain morphogenesis through Otx gene dosage requirement
    • Acampora D., Avantaggiato V., Tuorto F., Simeone A. Genetic control of brain morphogenesis through Otx gene dosage requirement. Development. 124:1997;3639-3650.
    • (1997) Development , vol.124 , pp. 3639-3650
    • Acampora, D.1    Avantaggiato, V.2    Tuorto, F.3    Simeone, A.4
  • 2
    • 0030050751 scopus 로고    scopus 로고
    • A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain
    • Ang S.L., Jin O., Rhinn M., Daigle N., Stevenson L., Rossant J. A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain. Development. 122:1996;243-252.
    • (1996) Development , vol.122 , pp. 243-252
    • Ang, S.L.1    Jin, O.2    Rhinn, M.3    Daigle, N.4    Stevenson, L.5    Rossant, J.6
  • 3
    • 0023625090 scopus 로고
    • Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
    • Angel P., Imagawa M., Chiu R., Stein B., Imbra R.J., Rahmsdorf H.J., Jonat C., Herrlich P., Karin M. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell. 49:1987;729-739.
    • (1987) Cell , vol.49 , pp. 729-739
    • Angel, P.1    Imagawa, M.2    Chiu, R.3    Stein, B.4    Imbra, R.J.5    Rahmsdorf, H.J.6    Jonat, C.7    Herrlich, P.8    Karin, M.9
  • 4
    • 0029164897 scopus 로고
    • Determination events in the nervous system of the vertebrate embryo
    • Bally-Cuif L., Wassef M. Determination events in the nervous system of the vertebrate embryo. Curr. Opin. Genet. Dev. 5:1995;450-458.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 450-458
    • Bally-Cuif, L.1    Wassef, M.2
  • 5
    • 0029163144 scopus 로고
    • Involvement of Wnt-1 in the formation of the mes/metencephalic boundary
    • Bally-Cuif L., Cholley B., Wassef M. Involvement of Wnt-1 in the formation of the mes/metencephalic boundary. Mech. Dev. 53:1995;23-34.
    • (1995) Mech. Dev. , vol.53 , pp. 23-34
    • Bally-Cuif, L.1    Cholley, B.2    Wassef, M.3
  • 6
    • 0027378294 scopus 로고
    • Emx and Otx homeobox genes in the developing mouse brain
    • Boncinelli E., Gulisano M., Broccoli V. Emx and Otx homeobox genes in the developing mouse brain. J. Neurobiol. 24:1993;1356-1366.
    • (1993) J. Neurobiol. , vol.24 , pp. 1356-1366
    • Boncinelli, E.1    Gulisano, M.2    Broccoli, V.3
  • 7
    • 0027232546 scopus 로고
    • Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries
    • Bulfone A., Puelles L., Porteus M.H., Frohman M.A., Martin G.R., Rubenstein J.L. Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. J. Neurosci. 13:1993;3155-3172.
    • (1993) J. Neurosci. , vol.13 , pp. 3155-3172
    • Bulfone, A.1    Puelles, L.2    Porteus, M.H.3    Frohman, M.A.4    Martin, G.R.5    Rubenstein, J.L.6
  • 8
    • 0028959288 scopus 로고
    • The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo
    • Crossley P.H., Martin G.R. The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development. 121:1995;439-451.
    • (1995) Development , vol.121 , pp. 439-451
    • Crossley, P.H.1    Martin, G.R.2
  • 9
    • 15844384249 scopus 로고    scopus 로고
    • Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development
    • Erkman L., et al. Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development. Nature. 381:1996;603-606.
    • (1996) Nature , vol.381 , pp. 603-606
    • Erkman, L.1
  • 10
    • 18344400664 scopus 로고
    • Molecular organization of the rat glia-derived nexin/ protease nexin-1 promoter
    • Ernø H., Monard D. Molecular organization of the rat glia-derived nexin/ protease nexin-1 promoter. Gene Exp. 3:1993;163-174.
    • (1993) Gene Exp. , vol.3 , pp. 163-174
    • Ernø, H.1    Monard, D.2
  • 11
    • 0031259753 scopus 로고    scopus 로고
    • Inhibitory effects of ventral signals on the development of Brn-3.0-expressing neurons in the dorsal spinal cord
    • Fedtsova N., Turner E.E. Inhibitory effects of ventral signals on the development of Brn-3.0-expressing neurons in the dorsal spinal cord. Dev. Biol. 190:1997;18-31.
    • (1997) Dev. Biol. , vol.190 , pp. 18-31
    • Fedtsova, N.1    Turner, E.E.2
  • 12
    • 0025979257 scopus 로고
    • Activation of junB by PKC and PKA signal transduction through a novel cis-acting element
    • de Groot R.P., Auwerx J., Karperien M., Staels B., Kruijer W. Activation of junB by PKC and PKA signal transduction through a novel cis-acting element. Nucleic Acids Res. 19:1991;775-781.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 775-781
    • De Groot, R.P.1    Auwerx, J.2    Karperien, M.3    Staels, B.4    Kruijer, W.5
  • 14
    • 0029935909 scopus 로고    scopus 로고
    • The B-cell activator Bob1 shows DNA sequence-dependent complex formation with Oct-1/Oct-2 factors, leading to differential promoter activation
    • Gstaiger M., Georgiev O., van Leeuwen H., van der Vliet P., Schaffner W. The B-cell activator Bob1 shows DNA sequence-dependent complex formation with Oct-1/Oct-2 factors, leading to differential promoter activation. EMBO J. 15:1996;2781-2790.
    • (1996) EMBO J. , vol.15 , pp. 2781-2790
    • Gstaiger, M.1    Georgiev, O.2    Van Leeuwen, H.3    Van Der Vliet, P.4    Schaffner, W.5
  • 15
    • 0029009482 scopus 로고
    • POU-2-a zebrafish gene active during cleavage stages and in the early hindbrain
    • Hauptmann G., Gerster T. POU-2-a zebrafish gene active during cleavage stages and in the early hindbrain. Mech. Dev. 51:1995;127-138.
    • (1995) Mech. Dev. , vol.51 , pp. 127-138
    • Hauptmann, G.1    Gerster, T.2
  • 16
    • 0029896684 scopus 로고    scopus 로고
    • Complex expression of the zp-50 pou gene in the embryonic zebrafish brain is altered by overexpression of sonic hedgehog
    • Hauptmann G., Gerster T. Complex expression of the zp-50 pou gene in the embryonic zebrafish brain is altered by overexpression of sonic hedgehog. Development. 122:1996;1769-1780.
    • (1996) Development , vol.122 , pp. 1769-1780
    • Hauptmann, G.1    Gerster, T.2
  • 17
    • 0029080235 scopus 로고
    • Wnt expression patterns in chick embryo nervous system
    • Hollyday M., McMahon J.A., McMahon A.P. Wnt expression patterns in chick embryo nervous system. Mech. Dev. 52:1995;9-25.
    • (1995) Mech. Dev. , vol.52 , pp. 9-25
    • Hollyday, M.1    McMahon, J.A.2    McMahon, A.P.3
  • 18
    • 0023663116 scopus 로고
    • Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP
    • Imagawa M., Chiu R., Karin M. Transcription factor AP-2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP. Cell. 51:1987;251-260.
    • (1987) Cell , vol.51 , pp. 251-260
    • Imagawa, M.1    Chiu, R.2    Karin, M.3
  • 21
    • 1842377452 scopus 로고    scopus 로고
    • Protease Nexin-1 is expressed at the mouse met-/mesencephalic junction and FGF signaling regulates its promoter activity in primary met-/mesencephalic cells
    • Küry P., Schaeren-Wiemers N., Monard D. Protease Nexin-1 is expressed at the mouse met-/mesencephalic junction and FGF signaling regulates its promoter activity in primary met-/mesencephalic cells. Development. 124:1997;1251-1262.
    • (1997) Development , vol.124 , pp. 1251-1262
    • Küry, P.1    Schaeren-Wiemers, N.2    Monard, D.3
  • 22
    • 0030933498 scopus 로고    scopus 로고
    • Evidence that FGF8 signaling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain
    • Lee S.M., Danielian P.S., Fritzsch B., McMahon A.P. Evidence that FGF8 signaling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. Development. 124:1997;959-969.
    • (1997) Development , vol.124 , pp. 959-969
    • Lee, S.M.1    Danielian, P.S.2    Fritzsch, B.3    McMahon, A.P.4
  • 23
    • 0027739734 scopus 로고
    • Spacing and orientation of bipartite DNA-binding motifs as potential functional determinants for POU domain factors
    • Li P., He X., Gerrero M.R., Mok M., Aggarwal A., Rosenfeld M.G. Spacing and orientation of bipartite DNA-binding motifs as potential functional determinants for POU domain factors. Genes Dev. 7:1993;2483-2496.
    • (1993) Genes Dev. , vol.7 , pp. 2483-2496
    • Li, P.1    He, X.2    Gerrero, M.R.3    Mok, M.4    Aggarwal, A.5    Rosenfeld, M.G.6
  • 24
    • 0026632820 scopus 로고
    • Brain-4: A novel mammalian POU domain transcription factor exhibiting restricted brain-specific expression
    • Mathis J.M., Simmons D.M., He X., Swanson L.W., Rosenfeld M.G. Brain-4: a novel mammalian POU domain transcription factor exhibiting restricted brain-specific expression. EMBO J. 11:1992;2551-2561.
    • (1992) EMBO J. , vol.11 , pp. 2551-2561
    • Mathis, J.M.1    Simmons, D.M.2    He, X.3    Swanson, L.W.4    Rosenfeld, M.G.5
  • 25
    • 0029808591 scopus 로고    scopus 로고
    • Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons
    • McEvilly R.J., Erkman L., Luo L., Sawchenko P.E., Ryan A.F., Rosenfeld M.G. Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 384:1996;574-577.
    • (1996) Nature , vol.384 , pp. 574-577
    • McEvilly, R.J.1    Erkman, L.2    Luo, L.3    Sawchenko, P.E.4    Ryan, A.F.5    Rosenfeld, M.G.6
  • 26
    • 0026719855 scopus 로고
    • The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum
    • McMahon A.P., Joyner A.L., Bradley A., McMahon J.A. The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell. 69:1992;581-595.
    • (1992) Cell , vol.69 , pp. 581-595
    • McMahon, A.P.1    Joyner, A.L.2    Bradley, A.3    McMahon, J.A.4
  • 27
    • 0030468934 scopus 로고    scopus 로고
    • The caudal limit of Otx2 gene expression as a marker of the midbrain/hindbrain boundary: A study using in situ hybridisation and chick/quail homotopic grafts
    • Millet S., Bloch-Gallego E., Simeone A., Alvarado-Mallart R.M. The caudal limit of Otx2 gene expression as a marker of the midbrain/hindbrain boundary: a study using in situ hybridisation and chick/quail homotopic grafts. Development. 122:1996;3785-3797.
    • (1996) Development , vol.122 , pp. 3785-3797
    • Millet, S.1    Bloch-Gallego, E.2    Simeone, A.3    Alvarado-Mallart, R.M.4
  • 28
    • 0342759569 scopus 로고
    • Isolation and sequence-specific DNA binding of the Antennapedia homeodomain
    • Muller M., Affolter M., Leupin W., Otting G., Wuthrich K., Gehring W.J. Isolation and sequence-specific DNA binding of the Antennapedia homeodomain. EMBO J. 7:1988;4299-4304.
    • (1988) EMBO J. , vol.7 , pp. 4299-4304
    • Muller, M.1    Affolter, M.2    Leupin, W.3    Otting, G.4    Wuthrich, K.5    Gehring, W.J.6
  • 29
    • 13344275857 scopus 로고
    • The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse
    • Nakai S., et al. The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse. Genes Dev. 9:1995;3109-3121.
    • (1995) Genes Dev. , vol.9 , pp. 3109-3121
    • Nakai, S.1
  • 31
    • 0025981310 scopus 로고
    • Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region
    • Prendergast G.C., Ziff E.B. Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region. Science. 251:1991;186-189.
    • (1991) Science , vol.251 , pp. 186-189
    • Prendergast, G.C.1    Ziff, E.B.2
  • 32
    • 0030918673 scopus 로고    scopus 로고
    • POU domain family values: Flexibility, partnerships, and developmental codes
    • Ryan A.K., Rosenfeld M.G. POU domain family values: flexibility, partnerships, and developmental codes. Genes Dev. 11:1997;1207-1225.
    • (1997) Genes Dev. , vol.11 , pp. 1207-1225
    • Ryan, A.K.1    Rosenfeld, M.G.2
  • 33
    • 0029125995 scopus 로고
    • Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1
    • Rowitch D.H., McMahon A.P. Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1. Mech. Dev. 52:1995;3-8.
    • (1995) Mech. Dev. , vol.52 , pp. 3-8
    • Rowitch, D.H.1    McMahon, A.P.2
  • 34
    • 0015716692 scopus 로고
    • A rapid, sensitive and specific method for the determination of proteins in dilute solution
    • Schaffner W., Weissmann C. A rapid, sensitive and specific method for the determination of proteins in dilute solution. Anal. Biochem. 56:1973;502-514.
    • (1973) Anal. Biochem. , vol.56 , pp. 502-514
    • Schaffner, W.1    Weissmann, C.2
  • 36
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
    • Schreiber E., Matthias P., Müller M.M., Schaffner W. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res. 17:1989;6419-6420.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 6419-6420
    • Schreiber, E.1    Matthias, P.2    Müller, M.M.3    Schaffner, W.4
  • 37
    • 0029967024 scopus 로고    scopus 로고
    • B-cell-specific co-activator OBF-1/OCA-B/Bob1 required for immune response and germinal center formation
    • Schubart D.B., Rolink A., Kosco-Vilbois M.H., Botteri F., Matthias P. B-cell-specific co-activator OBF-1/OCA-B/Bob1 required for immune response and germinal center formation. Nature. 383:1996;538-542.
    • (1996) Nature , vol.383 , pp. 538-542
    • Schubart, D.B.1    Rolink, A.2    Kosco-Vilbois, M.H.3    Botteri, F.4    Matthias, P.5
  • 38
    • 0026354237 scopus 로고
    • Mitotic phosphorylation of the Oct-1 homeodomain and regulation of Oct-1 DNA binding activity
    • Segil N., Roberts S.B., Heintz N. Mitotic phosphorylation of the Oct-1 homeodomain and regulation of Oct-1 DNA binding activity. Science. 254:1991;1814-1816.
    • (1991) Science , vol.254 , pp. 1814-1816
    • Segil, N.1    Roberts, S.B.2    Heintz, N.3
  • 39
    • 0022480751 scopus 로고
    • A lymphoid-specific protein binding to the octamer motif of the immunoglobulin genes
    • Staudt L.M., Singh H., Sen R., Wirth T., Sharp P.A., Baltimore D. A lymphoid-specific protein binding to the octamer motif of the immunoglobulin genes. Nature. 323:1986;640-643.
    • (1986) Nature , vol.323 , pp. 640-643
    • Staudt, L.M.1    Singh, H.2    Sen, R.3    Wirth, T.4    Sharp, P.A.5    Baltimore, D.6
  • 40
    • 0028207924 scopus 로고
    • Roles of Pax-genes in developing an adult brain as suggested by expression patterns
    • Stoykova A., Gruss P. Roles of Pax-genes in developing an adult brain as suggested by expression patterns. J. Neurosci. 14:1994;1395-1412.
    • (1994) J. Neurosci. , vol.14 , pp. 1395-1412
    • Stoykova, A.1    Gruss, P.2
  • 42
    • 0030851192 scopus 로고    scopus 로고
    • Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function
    • Wassarman K.M., Lewandoski M., Campbell K., Joyner A.L., Rubenstein J.L., Martinez S., Martin G.R. Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. Development. 124:1997;2923-2934.
    • (1997) Development , vol.124 , pp. 2923-2934
    • Wassarman, K.M.1    Lewandoski, M.2    Campbell, K.3    Joyner, A.L.4    Rubenstein, J.L.5    Martinez, S.6    Martin, G.R.7
  • 43
    • 0028310311 scopus 로고
    • Multiple developmental defects in Engrailed-1 mutant mice: An early mid-hindbrain deletion and patterning defects in forelimbs and sternum
    • Wurst W., Auerbach A.B., Joyner A.L. Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum. Development. 120:1994;2065-2075.
    • (1994) Development , vol.120 , pp. 2065-2075
    • Wurst, W.1    Auerbach, A.B.2    Joyner, A.L.3
  • 44
    • 0001093537 scopus 로고
    • Gene and enhancer trap screens in ES cell chimeras
    • A.L. Joyner. Oxford: Oxford University Press
    • Zacho J., Gossler A. Gene and enhancer trap screens in ES cell chimeras. Joyner A.L. Gene Targeting: a Practical Approach. 1993;181 Oxford University Press, Oxford.
    • (1993) Gene Targeting: A Practical Approach , pp. 181
    • Zacho, J.1    Gossler, A.2
  • 45
    • 0030028543 scopus 로고    scopus 로고
    • The restricted expression pattern of the POU factor Oct-6 during early development of the mouse nervous system
    • Zwart R., Broos L., Grosveld G., Meijer D. The restricted expression pattern of the POU factor Oct-6 during early development of the mouse nervous system. Mech. Dev. 54:1996;185-194.
    • (1996) Mech. Dev. , vol.54 , pp. 185-194
    • Zwart, R.1    Broos, L.2    Grosveld, G.3    Meijer, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.