메뉴 건너뛰기




Volumn 113, Issue 1, 2007, Pages 1-12

Assessing the cognitive impact of Alzheimer disease pathology and vascular burden in the aging brain: The Geneva experience

Author keywords

Clinicopathological correlations; Dementia; Neurofibrillary tangles; Neuropathology

Indexed keywords

AMYLOID BETA PROTEIN;

EID: 33751245916     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-006-0144-y     Document Type: Review
Times cited : (88)

References (109)
  • 1
    • 0026743110 scopus 로고
    • Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease
    • Arriagada PV, Marzloff K, Hyman BT (1992) Distribution of Alzheimer-type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease. Neurology 42:1681-1688
    • (1992) Neurology , vol.42 , pp. 1681-1688
    • Arriagada, P.V.1    Marzloff, K.2    Hyman, B.T.3
  • 2
    • 0017358355 scopus 로고
    • Neuronal loss, neurofibrillary tangles and granulovacuolar degeneration in the hippocampus with ageing and dementia. A quantitative study
    • (Berl)
    • Ball MJ (1977) Neuronal loss, neurofibrillary tangles and granulovacuolar degeneration in the hippocampus with ageing and dementia. A quantitative study. Acta Neuropathol (Berl) 37:111-118
    • (1977) Acta Neuropathol , vol.37 , pp. 111-118
    • Ball, M.J.1
  • 3
    • 0029877684 scopus 로고    scopus 로고
    • Correlations between mental state and quantitative neuropathology in the Vienna Longitudinal Study on Dementia
    • Bancher C, Jellinger K, Lassmann H, Fischer P, Leblhuber F (1996) Correlations between mental state and quantitative neuropathology in the Vienna Longitudinal Study on Dementia. Eur Arch Psychiatry Clin Neurosci 246:137-146
    • (1996) Eur Arch Psychiatry Clin Neurosci , vol.246 , pp. 137-146
    • Bancher, C.1    Jellinger, K.2    Lassmann, H.3    Fischer, P.4    Leblhuber, F.5
  • 4
    • 0024393488 scopus 로고
    • About the presence of paired helical filaments in dystrophic neurites participating in the plaque formation
    • (Berl)
    • Barcikowska M, Wisniewski HM, Bancher C, Grundke-Iqbal I (1989) About the presence of paired helical filaments in dystrophic neurites participating in the plaque formation. Acta Neuropathol (Berl) 78:225-231
    • (1989) Acta Neuropathol , vol.78 , pp. 225-231
    • Barcikowska, M.1    Wisniewski, H.M.2    Bancher, C.3    Grundke-Iqbal, I.4
  • 8
    • 0028213511 scopus 로고
    • Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of elderly patients: A quantitative evaluation of a one-year autopsy population from a geriatric hospital
    • Bouras C, Hof PR, Giannakopoulos P, Michel JP, Morrison JH (1994) Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of elderly patients: A quantitative evaluation of a one-year autopsy population from a geriatric hospital. Cereb Cortex 4:138-150
    • (1994) Cereb Cortex , vol.4 , pp. 138-150
    • Bouras, C.1    Hof, P.R.2    Giannakopoulos, P.3    Michel, J.P.4    Morrison, J.H.5
  • 9
    • 0027316077 scopus 로고
    • Neurofibrillary tangle densities in the hippocampal formation in a non-demented population define subgroups of patients with differential early pathologic changes
    • Bouras C, Hof PR, Morrison JH (1993) Neurofibrillary tangle densities in the hippocampal formation in a non-demented population define subgroups of patients with differential early pathologic changes. Neurosci Lett 153:131-135
    • (1993) Neurosci Lett , vol.153 , pp. 131-135
    • Bouras, C.1    Hof, P.R.2    Morrison, J.H.3
  • 11
    • 33749150163 scopus 로고    scopus 로고
    • Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
    • (Berl)
    • Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K (2006) Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol (Berl) 112:388-403
    • (2006) Acta Neuropathol , vol.112 , pp. 388-403
    • Braak, H.1    Alafuzoff, I.2    Arzberger, T.3    Kretzschmar, H.4    Del Tredici, K.5
  • 12
    • 0030668423 scopus 로고    scopus 로고
    • Diagnostic criteria for neuropathologic assessment of Alzheimer's disease
    • Braak H, Braak E (1997) Diagnostic criteria for neuropathologic assessment of Alzheimer's disease. Neurobiol Aging 18:S85-S88
    • (1997) Neurobiol Aging , vol.18
    • Braak, H.1    Braak, E.2
  • 13
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • (Berl)
    • Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (Berl) 82:239-259
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 14
    • 0031302684 scopus 로고    scopus 로고
    • Staging of Alzheimer-related cortical destruction
    • (discussion 269-272)
    • Braak H, Braak E (1997) Staging of Alzheimer-related cortical destruction. Int Psychogeriatr 9(Suppl 1):257-261 (discussion 269-272)
    • (1997) Int Psychogeriatr , vol.9 , Issue.SUPPL. 1 , pp. 257-261
    • Braak, H.1    Braak, E.2
  • 15
    • 0029013727 scopus 로고
    • Staging of Alzheimer's disease-related neurofibrillary changes
    • (discussion 278-284)
    • Braak H, Braak E (1995) Staging of Alzheimer's disease-related neurofibrillary changes. Neurobiol Aging 16:271-278 (discussion 278-284)
    • (1995) Neurobiol Aging , vol.16 , pp. 271-278
    • Braak, H.1    Braak, E.2
  • 16
    • 0027490614 scopus 로고
    • Staging of Alzheimer-related cortical destruction
    • Braak H, Braak E, Bohl J (1993) Staging of Alzheimer-related cortical destruction. Eur Neurol 33:403-408
    • (1993) Eur Neurol , vol.33 , pp. 403-408
    • Braak, H.1    Braak, E.2    Bohl, J.3
  • 17
    • 0027724463 scopus 로고
    • Relation between MRI features and dementia in cerebrovascular disease patients with leukoaraiosis: A longitudinal study
    • Bracco L, Campani D, Baratti E, Lippi A, Inzitari D, Pracucci G, Amaducci L (1993) Relation between MRI features and dementia in cerebrovascular disease patients with leukoaraiosis: A longitudinal study. J Neurol Sci 120:131-136
    • (1993) J Neurol Sci , vol.120 , pp. 131-136
    • Bracco, L.1    Campani, D.2    Baratti, E.3    Lippi, A.4    Inzitari, D.5    Pracucci, G.6    Amaducci, L.7
  • 20
    • 0036098423 scopus 로고    scopus 로고
    • Progressive reduction of synaptophysin message in single neurons in Alzheimer disease
    • Callahan LM, Vaules WA, Coleman PD (2002) Progressive reduction of synaptophysin message in single neurons in Alzheimer disease. J Neuropathol Exp Neurol 61:384-395
    • (2002) J Neuropathol Exp Neurol , vol.61 , pp. 384-395
    • Callahan, L.M.1    Vaules, W.A.2    Coleman, P.D.3
  • 22
    • 0030464914 scopus 로고    scopus 로고
    • Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease
    • Cummings BJ, Pike CJ, Shankle R, Cotman CW (1996) Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease. Neurobiol Aging 17:921-933
    • (1996) Neurobiol Aging , vol.17 , pp. 921-933
    • Cummings, B.J.1    Pike, C.J.2    Shankle, R.3    Cotman, C.W.4
  • 23
    • 0027203627 scopus 로고
    • Frontal-subcortical circuits and human behavior
    • Cummings JL (1993) Frontal-subcortical circuits and human behavior. Arch Neurol 50:873-880
    • (1993) Arch Neurol , vol.50 , pp. 873-880
    • Cummings, J.L.1
  • 27
    • 0027410176 scopus 로고
    • Beta A4 deposits are constant in the brain of the oldest old: An immunocytochemical study of 20 French centenarians
    • Delaere P, He Y, Fayet G, Duyckaerts C, Hauw JJ (1993) Beta A4 deposits are constant in the brain of the oldest old: An immunocytochemical study of 20 French centenarians. Neurobiol Aging 14:191-194
    • (1993) Neurobiol Aging , vol.14 , pp. 191-194
    • Delaere, P.1    He, Y.2    Fayet, G.3    Duyckaerts, C.4    Hauw, J.J.5
  • 28
    • 0033202882 scopus 로고    scopus 로고
    • Cerebral lacunae: Still under debate
    • (Paris)
    • Derouesne C, Poirier J (1999) [Cerebral lacunae: Still under debate]. Rev Neurol (Paris) 155:823-831
    • (1999) Rev Neurol , vol.155 , pp. 823-831
    • Derouesne, C.1    Poirier, J.2
  • 29
    • 0036714559 scopus 로고    scopus 로고
    • Incidence of dementia after ischemic stroke: Results of a longitudinal study
    • Desmond DW, Moroney JT, Sano M, Stern Y (2002) Incidence of dementia after ischemic stroke: Results of a longitudinal study. Stroke 33:2254-2260
    • (2002) Stroke , vol.33 , pp. 2254-2260
    • Desmond, D.W.1    Moroney, J.T.2    Sano, M.3    Stern, Y.4
  • 30
    • 0030660554 scopus 로고    scopus 로고
    • Neuropathological diagnosis of Alzheimer's disease: A perspective from longitudinal clinicopathological studies
    • Dickson DW (1997) Neuropathological diagnosis of Alzheimer's disease: A perspective from longitudinal clinicopathological studies. Neurobiol Aging 18:S21-S26
    • (1997) Neurobiol Aging , vol.18
    • Dickson, D.W.1
  • 31
    • 0029078972 scopus 로고
    • Correlations of synaptic and pathological markers with cognition of the elderly
    • (discussion 298-304)
    • Dickson DW, Crystal HA, Bevona C, Honer W, Vincent I, Davies P (1995) Correlations of synaptic and pathological markers with cognition of the elderly. Neurobiol Aging 16:285-298 (discussion 298-304)
    • (1995) Neurobiol Aging , vol.16 , pp. 285-298
    • Dickson, D.W.1    Crystal, H.A.2    Bevona, C.3    Honer, W.4    Vincent, I.5    Davies, P.6
  • 34
    • 0023688264 scopus 로고
    • Accuracy of the clinical diagnosis of vascular dementia: A prospective clinical and post-mortem neuropathological study
    • Erkinjuntti T, Haltia M, Palo J, Sulkava R, Paetau A (1988) Accuracy of the clinical diagnosis of vascular dementia: A prospective clinical and post-mortem neuropathological study. J Neurol Neurosurg Psychiatry 51:1037-1044
    • (1988) J Neurol Neurosurg Psychiatry , vol.51 , pp. 1037-1044
    • Erkinjuntti, T.1    Haltia, M.2    Palo, J.3    Sulkava, R.4    Paetau, A.5
  • 35
    • 0034114826 scopus 로고    scopus 로고
    • Which vascular lesions are of importance in vascular dementia?
    • Esiri MM (2000) Which vascular lesions are of importance in vascular dementia? Ann N Y Acad Sci 903:239-243
    • (2000) Ann N Y Acad Sci , vol.903 , pp. 239-243
    • Esiri, M.M.1
  • 36
    • 0033546881 scopus 로고    scopus 로고
    • Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease
    • [letter]
    • Esiri MM, Nagy Z, Smith MZ, Barnetson L, Smith AD (1999) Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease [letter]. Lancet 354:919-920
    • (1999) Lancet , vol.354 , pp. 919-920
    • Esiri, M.M.1    Nagy, Z.2    Smith, M.Z.3    Barnetson, L.4    Smith, A.D.5
  • 37
    • 0030670874 scopus 로고    scopus 로고
    • Neuropathological assessment of the lesions of significance in vascular dementia
    • Esiri MM, Wilcock GK, Morris JH (1997) Neuropathological assessment of the lesions of significance in vascular dementia. J Neurol Neurosurg Psychiatry 63:749-753
    • (1997) J Neurol Neurosurg Psychiatry , vol.63 , pp. 749-753
    • Esiri, M.M.1    Wilcock, G.K.2    Morris, J.H.3
  • 38
  • 39
    • 0035047718 scopus 로고    scopus 로고
    • Cerebral microvascular pathology in aging and Alzheimer's disease
    • Farkas E, Luiten PG (2001) Cerebral microvascular pathology in aging and Alzheimer's disease. Prog Neurobiol 64:575-611
    • (2001) Prog Neurobiol , vol.64 , pp. 575-611
    • Farkas, E.1    Luiten, P.G.2
  • 40
    • 8644240928 scopus 로고    scopus 로고
    • Vascular pathologies and cognition in a population-based cohort of elderly people
    • Fernando MS, Ince PG (2004) Vascular pathologies and cognition in a population-based cohort of elderly people. J Neurol Sci 226:13-17
    • (2004) J Neurol Sci , vol.226 , pp. 13-17
    • Fernando, M.S.1    Ince, P.G.2
  • 41
    • 0016823810 scopus 로고
    • "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR (1975) "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12:189-198
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 42
    • 0034686939 scopus 로고    scopus 로고
    • Relation between age-related decline in intelligence and cerebral white-matter hyperintensities in healthy octogenarians: A longitudinal study
    • Garde E, Mortensen EL, Krabbe K, Rostrup E, Larsson HB (2000) Relation between age-related decline in intelligence and cerebral white-matter hyperintensities in healthy octogenarians: A longitudinal study. Lancet 356:628-634
    • (2000) Lancet , vol.356 , pp. 628-634
    • Garde, E.1    Mortensen, E.L.2    Krabbe, K.3    Rostrup, E.4    Larsson, H.B.5
  • 45
    • 0028884524 scopus 로고
    • Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of very old patients
    • Giannakopoulos P, Hof PR, Giannakopoulos AS, Herrmann FR, Michel JP, Bouras C (1995) Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of very old patients. Arch Neurol 52:1150-1159
    • (1995) Arch Neurol , vol.52 , pp. 1150-1159
    • Giannakopoulos, P.1    Hof, P.R.2    Giannakopoulos, A.S.3    Herrmann, F.R.4    Michel, J.P.5    Bouras, C.6
  • 46
    • 0029857822 scopus 로고    scopus 로고
    • Distinct patterns of neuronal loss and Alzheimer's disease lesion distribution in elderly individuals older than 90 years
    • Giannakopoulos P, Hof PR, Kövari E, Vallet PG, Bouras C (1996) Distinct patterns of neuronal loss and Alzheimer's disease lesion distribution in elderly individuals older than 90 years. J Neuropathol Exp Neurol 55:1210-1220
    • (1996) J. Neuropathol Exp Neurol , vol.55 , pp. 1210-1220
    • Giannakopoulos, P.1    Hof, P.R.2    Kövari, E.3    Vallet, P.G.4    Bouras, C.5
  • 51
    • 0033981060 scopus 로고    scopus 로고
    • The Oregon brain aging study: Neuropathology accompanying healthy aging in the oldest old
    • Green MS, Kaye JA, Ball MJ (2000) The Oregon brain aging study: neuropathology accompanying healthy aging in the oldest old. Neurology 54:105-113
    • (2000) Neurology , vol.54 , pp. 105-113
    • Green, M.S.1    Kaye, J.A.2    Ball, M.J.3
  • 53
    • 0031792823 scopus 로고    scopus 로고
    • Variation in hippocampal neuron number with age and brain volume
    • Harding AJ, Halliday GM, Kril JJ (1998) Variation in hippocampal neuron number with age and brain volume. Cereb Cortex 8:710-718
    • (1998) Cereb Cortex , vol.8 , pp. 710-718
    • Harding, A.J.1    Halliday, G.M.2    Kril, J.J.3
  • 54
    • 0026726282 scopus 로고
    • Evidence for early vulnerability of the medial and inferior aspects of the temporal lobe in an 82 year old patient with preclinical signs of dementia: Regional and laminar distribution of neurofibrillary tangles and senile plaques
    • Hof PR, Bierer LM, Perl DP, Delacourte A, Buée L, Bouras C, Morrison JH (1992) Evidence for early vulnerability of the medial and inferior aspects of the temporal lobe in an 82 year old patient with preclinical signs of dementia: Regional and laminar distribution of neurofibrillary tangles and senile plaques. Arch Neurol 49:946-953
    • (1992) Arch Neurol , vol.49 , pp. 946-953
    • Hof, P.R.1    Bierer, L.M.2    Perl, D.P.3    Delacourte, A.4    Buée, L.5    Bouras, C.6    Morrison, J.H.7
  • 56
    • 0025240790 scopus 로고
    • A quantitative histological study of early clinical and preclinical Alzheimer's disease
    • Hubbard BM, Fenton GW, Anderson JM (1990) A quantitative histological study of early clinical and preclinical Alzheimer's disease. Neuropathol Appl Neurobiol 16:111-121
    • (1990) Neuropathol Appl Neurobiol , vol.16 , pp. 111-121
    • Hubbard, B.M.1    Fenton, G.W.2    Anderson, J.M.3
  • 58
    • 0031593785 scopus 로고    scopus 로고
    • Neuropathological and neuropsychological changes in "normal" aging: Evidence for preclinical Alzheimer disease in cognitively normal individuals
    • Hulette CM, Welsh-Bohmer KA, Murray MG, Saunders AM, Mash DC, McIntyre LM (1998) Neuropathological and neuropsychological changes in "normal" aging: Evidence for preclinical Alzheimer disease in cognitively normal individuals. J Neuropathol Exp Neurol 57:1168-1174
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 1168-1174
    • Hulette, C.M.1    Welsh-Bohmer, K.A.2    Murray, M.G.3    Saunders, A.M.4    Mash, D.C.5    McIntyre, L.M.6
  • 60
    • 14844335655 scopus 로고    scopus 로고
    • Understanding the pathology of vascular cognitive impairment
    • Jellinger KA (2005) Understanding the pathology of vascular cognitive impairment. J Neurol Sci 229-230:57-63
    • (2005) J Neurol Sci , vol.229-230 , pp. 57-63
    • Jellinger, K.A.1
  • 61
    • 0037208951 scopus 로고    scopus 로고
    • Incidence of cerebrovascular lesions in Alzheimer's disease: A postmortem study
    • (Berl)
    • Jellinger KA, Attems J (2003) Incidence of cerebrovascular lesions in Alzheimer's disease: A postmortem study. Acta Neuropathol (Berl) 105:14-17
    • (2003) Acta Neuropathol , vol.105 , pp. 14-17
    • Jellinger, K.A.1    Attems, J.2
  • 62
    • 0023905906 scopus 로고
    • Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques
    • Katzman R, Terry R, DeTeresa R, Brown T, Davies P, Fuld P, Renbing X, Peck A (1988) Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques. Ann Neurol 23:138-144
    • (1988) Ann Neurol , vol.23 , pp. 138-144
    • Katzman, R.1    Terry, R.2    DeTeresa, R.3    Brown, T.4    Davies, P.5    Fuld, P.6    Renbing, X.7    Peck, A.8
  • 66
    • 0036955813 scopus 로고    scopus 로고
    • Neuron loss from the hippocampus of Alzheimer's disease exceeds extracellular neurofibrillary tangle formation
    • (Berl)
    • Kril JJ, Patel S, Harding AJ, Halliday GM (2002) Neuron loss from the hippocampus of Alzheimer's disease exceeds extracellular neurofibrillary tangle formation. Acta Neuropathol (Berl) 103:370-376
    • (2002) Acta Neuropathol , vol.103 , pp. 370-376
    • Kril, J.J.1    Patel, S.2    Harding, A.J.3    Halliday, G.M.4
  • 67
    • 0033781291 scopus 로고    scopus 로고
    • Small concomitant vascular lesions do not influence rates of cognitive decline in patients with alzheimer disease
    • Lee JH, Olichney JM, Hansen LA, Hofstetter CR, Thal LJ (2000) Small concomitant vascular lesions do not influence rates of cognitive decline in patients with alzheimer disease. Arch Neurol 57:1474-1479
    • (2000) Arch Neurol , vol.57 , pp. 1474-1479
    • Lee, J.H.1    Olichney, J.M.2    Hansen, L.A.3    Hofstetter, C.R.4    Thal, L.J.5
  • 68
    • 0023222380 scopus 로고
    • Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: A quantitative study of visual and auditory cortices
    • Lewis DA, Campbell MJ, Terry RD, Morrison JH (1987) Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: A quantitative study of visual and auditory cortices. J Neurosci 7:1799-1808
    • (1987) J Neurosci , vol.7 , pp. 1799-1808
    • Lewis, D.A.1    Campbell, M.J.2    Terry, R.D.3    Morrison, J.H.4
  • 69
    • 0028942371 scopus 로고
    • Morphological imaging in the diagnosis of dementia. II. Vascular dementia
    • Leys D, Scheltens P, Vermersch P, Pruvo JP (1995) [Morphological imaging in the diagnosis of dementia. II. Vascular dementia]. Rev Med Interne 16:195-200
    • (1995) Rev Med Interne , vol.16 , pp. 195-200
    • Leys, D.1    Scheltens, P.2    Vermersch, P.3    Pruvo, J.P.4
  • 70
  • 72
    • 0027390458 scopus 로고
    • Quantitative synaptic alterations in the human neocortex during normal aging
    • Masliah E, Mallory M, Hansen L, DeTeresa R, Terry RD (1993) Quantitative synaptic alterations in the human neocortex during normal aging. Neurology 43:192-197
    • (1993) Neurology , vol.43 , pp. 192-197
    • Masliah, E.1    Mallory, M.2    Hansen, L.3    DeTeresa, R.4    Terry, R.D.5
  • 73
    • 0029892175 scopus 로고    scopus 로고
    • Cerebral amyloid deposition and diffuse plaques in "normal" aging: Evidence for presymptomatic and very mild Alzheimer's disease
    • Morris JC, Storandt M, McKeel DW Jr, Rubin EH, Price JL, Grant EA, Berg L (1996) Cerebral amyloid deposition and diffuse plaques in "normal" aging: Evidence for presymptomatic and very mild Alzheimer's disease. Neurology 46:707-719
    • (1996) Neurology , vol.46 , pp. 707-719
    • Morris, J.C.1    Storandt, M.2    McKeel Jr., D.W.3    Rubin, E.H.4    Price, J.L.5    Grant, E.A.6    Berg, L.7
  • 74
    • 0020956552 scopus 로고
    • Cortical neuronal counts in normal elderly controls and demented patients
    • Mountjoy CQ, Roth M, Evans NJ, Evans HM (1983) Cortical neuronal counts in normal elderly controls and demented patients. Neurobiol Aging 4:1-11
    • (1983) Neurobiol Aging , vol.4 , pp. 1-11
    • Mountjoy, C.Q.1    Roth, M.2    Evans, N.J.3    Evans, H.M.4
  • 76
    • 0038117796 scopus 로고    scopus 로고
    • Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline
    • Naslund J, Haroutunian V, Mohs R, Davis KL, Davies P, Greengard P, Buxbaum JD (2000) Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. JAMA 283:1571-1577
    • (2000) JAMA , vol.283 , pp. 1571-1577
    • Naslund, J.1    Haroutunian, V.2    Mohs, R.3    Davis, K.L.4    Davies, P.5    Greengard, P.6    Buxbaum, J.D.7
  • 77
    • 0035915621 scopus 로고    scopus 로고
    • Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales
    • Neuropathology Group of the Medical Research Council Cognitive Function, Ageing Study (MRC CFAS)
    • Neuropathology Group of the Medical Research Council Cognitive Function, Ageing Study (MRC CFAS) (2001) Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Lancet 357:169-175
    • (2001) Lancet , vol.357 , pp. 169-175
  • 78
    • 0345512210 scopus 로고
    • Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease
    • Pearson RC, Esiri MM, Hiorns RW, Wilcock GK, Powell TP (1985) Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease. Proc Natl Acad Sci USA 82:4531-4534
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 4531-4534
    • Pearson, R.C.1    Esiri, M.M.2    Hiorns, R.W.3    Wilcock, G.K.4    Powell, T.P.5
  • 79
    • 0025770134 scopus 로고
    • The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease
    • Price JL, Davis PB, Morris JC, White DL (1991) The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease. Neurobiol Aging 12:295-312
    • (1991) Neurobiol Aging , vol.12 , pp. 295-312
    • Price, J.L.1    Davis, P.B.2    Morris, J.C.3    White, D.L.4
  • 80
    • 0034849725 scopus 로고    scopus 로고
    • Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease
    • Price JL, Ko AI, Wade MJ, Tsou SK, McKeel DW, Morris JC (2001) Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease. Arch Neurol 58:1395-1402
    • (2001) Arch Neurol , vol.58 , pp. 1395-1402
    • Price, J.L.1    Ko, A.I.2    Wade, M.J.3    Tsou, S.K.4    McKeel, D.W.5    Morris, J.C.6
  • 81
    • 0032989712 scopus 로고    scopus 로고
    • Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease
    • Price JL, Morris JC (1999) Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease. Ann Neurol 45:358-368
    • (1999) Ann Neurol , vol.45 , pp. 358-368
    • Price, J.L.1    Morris, J.C.2
  • 82
    • 0035105729 scopus 로고    scopus 로고
    • Frontal lobe hypometabolism predicts cognitive decline in patients with lacunar infarcts
    • Reed BR, Eberling JL, Mungas D, Weiner M, Jagust WJ (2001) Frontal lobe hypometabolism predicts cognitive decline in patients with lacunar infarcts. Arch Neurol 58:493-497
    • (2001) Arch Neurol , vol.58 , pp. 493-497
    • Reed, B.R.1    Eberling, J.L.2    Mungas, D.3    Weiner, M.4    Jagust, W.J.5
  • 83
    • 11444250354 scopus 로고    scopus 로고
    • Early life linguistic ability, late life cognitive function, and neuropathology: Findings from the Nun Study
    • Riley KP, Snowdon DA, Desrosiers MF, Markesbery WR (2005) Early life linguistic ability, late life cognitive function, and neuropathology: findings from the Nun Study. Neurobiol Aging 26:341-347
    • (2005) Neurobiol Aging , vol.26 , pp. 341-347
    • Riley, K.P.1    Snowdon, D.A.2    Desrosiers, M.F.3    Markesbery, W.R.4
  • 85
    • 0027973771 scopus 로고
    • Hippocampal connectivity and Alzheimer's dementia: Effects of synapse loss and tangle frequency in a two-component model
    • Samuel W, Masliah E, Hill LR, Butters N, Terry R (1994) Hippocampal connectivity and Alzheimer's dementia: Effects of synapse loss and tangle frequency in a two-component model. Neurology 44:2081-2088
    • (1994) Neurology , vol.44 , pp. 2081-2088
    • Samuel, W.1    Masliah, E.2    Hill, L.R.3    Butters, N.4    Terry, R.5
  • 88
    • 0031046970 scopus 로고    scopus 로고
    • Volume and number of neurons of the human hippocampal formation in normal aging and Alzheimer's disease
    • Simic G, Kostovic I, Winblad B, Bogdanovic N (1997) Volume and number of neurons of the human hippocampal formation in normal aging and Alzheimer's disease. J Comp Neurol 379:482-494
    • (1997) J Comp Neurol , vol.379 , pp. 482-494
    • Simic, G.1    Kostovic, I.2    Winblad, B.3    Bogdanovic, N.4
  • 91
    • 0000354585 scopus 로고
    • Structural basis of the cognitive alterations in Alzheimer's disease
    • In: Terry RD, Katzman R, Bick KL (eds) Raven Press, New York
    • Terry RD, Masliah E, Hansen LA (1994) Structural basis of the cognitive alterations in Alzheimer's disease. In: Terry RD, Katzman R, Bick KL (eds) Alzheimer's disease. Raven Press, New York, pp 179-196
    • (1994) Alzheimer's Disease , pp. 179-196
    • Terry, R.D.1    Masliah, E.2    Hansen, L.A.3
  • 93
    • 0014326852 scopus 로고
    • Observations on the brains of non-demented old people
    • Tomlinson BE, Blessed G, Roth M (1968) Observations on the brains of non-demented old people. J Neurol Sci 7:331-356
    • (1968) J. Neurol Sci , vol.7 , pp. 331-356
    • Tomlinson, B.E.1    Blessed, G.2    Roth, M.3
  • 94
    • 0036449825 scopus 로고    scopus 로고
    • White matter lesions and dementia: MRI-pathological correlation
    • Udaka F, Sawada H, Kameyama M (2002) White matter lesions and dementia: MRI-pathological correlation. Ann N Y Acad Sci 977:411-415
    • (2002) Ann N Y Acad Sci , vol.977 , pp. 411-415
    • Udaka, F.1    Sawada, H.2    Kameyama, M.3
  • 95
    • 0021960718 scopus 로고
    • Alzheimer changes in nondemented patients younger than sixty-five: Possible early stages of Alzheimer's disease and senile dementia of Alzheimer type
    • Ulrich J (1985) Alzheimer changes in nondemented patients younger than sixty-five: Possible early stages of Alzheimer's disease and senile dementia of Alzheimer type. Ann Neurol 17:273-277
    • (1985) Ann Neurol , vol.17 , pp. 273-277
    • Ulrich, J.1
  • 96
    • 12944289492 scopus 로고    scopus 로고
    • Aging is associated with increased collagen type IV accumulation in the basal lamina of human cerebral microvessels
    • Uspenskaia O, Liebetrau M, Herms J, Danek A, Hamann GF (2004) Aging is associated with increased collagen type IV accumulation in the basal lamina of human cerebral microvessels. BMC Neurosci 5:37
    • (2004) BMC Neurosci , vol.5 , pp. 37
    • Uspenskaia, O.1    Liebetrau, M.2    Herms, J.3    Danek, A.4    Hamann, G.F.5
  • 101
    • 16244390510 scopus 로고    scopus 로고
    • Stereologic analysis of hippocampal Alzheimer's disease pathology in the oldest-old: Evidence for sparing of the entorhinal cortex and CA1 field
    • von Gunten A, Kövari E, Rivara CB, Bouras C, Hof PR, Giannakopoulos P (2005) Stereologic analysis of hippocampal Alzheimer's disease pathology in the oldest-old: Evidence for sparing of the entorhinal cortex and CA1 field. Exp Neurol 193:198-206
    • (2005) Exp Neurol , vol.193 , pp. 198-206
    • von Gunten, A.1    Kövari, E.2    Rivara, C.B.3    Bouras, C.4    Hof, P.R.5    Giannakopoulos, P.6
  • 102
    • 3242752879 scopus 로고    scopus 로고
    • Effect of white matter changes on cognitive impairment in patients with lacunar infarcts
    • Wen HM, Mok VC, Fan YH, Lam WW, Tang WK, Wong A, Huang RX, Wong KS (2004) Effect of white matter changes on cognitive impairment in patients with lacunar infarcts. Stroke 35:1826-1830
    • (2004) Stroke , vol.35 , pp. 1826-1830
    • Wen, H.M.1    Mok, V.C.2    Fan, Y.H.3    Lam, W.W.4    Tang, W.K.5    Wong, A.6    Huang, R.X.7    Wong, K.S.8
  • 103
    • 0027164617 scopus 로고
    • Regionally specific loss of neurons in the aging human hippocampus
    • West MJ (1993) Regionally specific loss of neurons in the aging human hippocampus. Neurobiol Aging 14:287-293
    • (1993) Neurobiol Aging , vol.14 , pp. 287-293
    • West, M.J.1
  • 104
    • 0028122463 scopus 로고
    • Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease
    • West MJ, Coleman PD, Flood DG, Troncoso JC (1994) Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet 344:769-772
    • (1994) Lancet , vol.344 , pp. 769-772
    • West, M.J.1    Coleman, P.D.2    Flood, D.G.3    Troncoso, J.C.4
  • 105
    • 0025327731 scopus 로고
    • Unbiased stereological estimation of the number of neurons in the human hippocampus
    • West MJ, Gundersen HJ (1990) Unbiased stereological estimation of the number of neurons in the human hippocampus. J Comp Neurol 296:1-22
    • (1990) J Comp Neurol , vol.296 , pp. 1-22
    • West, M.J.1    Gundersen, H.J.2
  • 106
    • 0019935804 scopus 로고
    • Plaques, tangles and dementia. A quantitative study
    • Wilcock GK, Esiri MM (1982) Plaques, tangles and dementia. A quantitative study. J Neurol Sci 56:343-356
    • (1982) J Neurol Sci , vol.56 , pp. 343-356
    • Wilcock, G.K.1    Esiri, M.M.2
  • 107
    • 0030713295 scopus 로고    scopus 로고
    • Diagnostic criteria for the neuropathological assessment of Alzheimer's disease: Current status and major issues
    • Wisniewski HM, Silverman W (1997) Diagnostic criteria for the neuropathological assessment of Alzheimer's disease: Current status and major issues. Neurobiol Aging 18:S43-S50
    • (1997) Neurobiol Aging , vol.18
    • Wisniewski, H.M.1    Silverman, W.2
  • 108
    • 0029034159 scopus 로고
    • White matter hyperintensities on MRI in the neurologically nondiseased elderly. Analysis of cohorts of consecutive subjects aged 55 to 85 years living at home
    • Ylikoski A, Erkinjuntti T, Raininko R, Sarna S, Sulkava R, Tilvis R (1995) White matter hyperintensities on MRI in the neurologically nondiseased elderly. Analysis of cohorts of consecutive subjects aged 55 to 85 years living at home. Stroke 26:1171-1177
    • (1995) Stroke , vol.26 , pp. 1171-1177
    • Ylikoski, A.1    Erkinjuntti, T.2    Raininko, R.3    Sarna, S.4    Sulkava, R.5    Tilvis, R.6
  • 109
    • 0036938669 scopus 로고    scopus 로고
    • Degenerative and vascular lesions of the brain have synergistic effects in dementia of the elderly
    • (Berl)
    • Zekry D, Duyckaerts C, Moulias R, Belmin J, Geoffre C, Herrmann F, Hauw JJ (2002) Degenerative and vascular lesions of the brain have synergistic effects in dementia of the elderly. Acta Neuropathol (Berl) 103:481-487
    • (2002) Acta Neuropathol , vol.103 , pp. 481-487
    • Zekry, D.1    Duyckaerts, C.2    Moulias, R.3    Belmin, J.4    Geoffre, C.5    Herrmann, F.6    Hauw, J.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.