The effects of additional pathology on the cognitive deficit in Alzheimer disease

Journal of Neuropathology and Experimental Neurology

Volumn 56, Issue 2, 1997, Pages 165-170

  Nagy, Zsuzsanna ^a,b   Esiri, Margaret M ^a   Jobst, Kim A ^a   Morris, James H ^a   King, Elizabeth M F ^a   Mcdonald, Brendan ^a   Joachim, Catharine ^a   Litchfield, Suzanne ^a   Barnetson, Lin ^a   Smith, A David ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b RADCLIFFE INFIRMARY   (United Kingdom)

Author keywords

Diffuse plaques; Neuritic plaques; Neurofibrillary tangles; Parkinson's disease; Vascular disease

Indexed keywords

ALZHEIMER DISEASE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE SEVERITY; HUMAN; HUMAN TISSUE; NEUROFIBRILLARY TANGLE; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SENILE PLAQUE;

EID: 0030815773     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199702000-00007     Document Type: Article

References (34)

1. Chui HC. Dementia. A review emphasizing clinicopathologic correlation and brain-behavior relationships. Arch Neurol 1989;46:806-14
2. Morris JC. Differential diagnosis of Alzheimer's disease. Clin Geriatr Med 1994;10:257-76
3. Munoz DG. The pathological basis of multi-infarct dementia. Alzheimer Dis Assoc Disord 1991;5:77-90
4. Peterson B, Summergrad P. Binswanger's disease (Part II): Pathogenesis of subcortical arteriosclerotic encephalopathy and its relation to other dementing processes. J Geriatr Psychiatry Neurol 1989;2:171-81
5. Cummings JL. Intellectual impairment in Parkinson's disease: Clinical, pathologic, and biochemical correlates. J Geriatr Psychiatry Neurol 1988;1:24-36
6. Cummings JL. The dementias of Parkinson's disease: Prevalence, characteristics, neurobiology, and comparison with dementia of the Alzheimer type. Eur Neurol 1988;28:15-23
7. Jellinger K. Neuropathological substrates of Alzheimer's disease and Parkinson's disease. J Neural Transm Suppl 1987;24:109-29
8. Hansen LA, Masliah E, Terry RD, Mirra SS. A neuropathological subset of Alzheimer's disease with concomitant Lewy body disease and spongiform change. Acta Neuropathol Berl 1989;78:194-201
9. Gibb WR. Dementia and Parkinson's disease. Br J Psychiatry 1989;154:596-614
10. Gibb WR, Mountjoy CQ, Mann DM, Lees AJ. A pathological study of the association between Lewy body disease and Alzheimer's disease. J Neurol Neurosurg Psychiatry 1989;52:701-8
11. Gibb WR, Mountjoy CQ, Mann DM, Lees AJ. The substantia nigra and ventral tegmental area in Alzheimer's disease and Down's syndrome. J Neurol Neurosurg Psychiatry 1989;52:193-200
12. Gibb WR, Luthert PJ. Dementia in Parkinson's disease and Lewy body disease. In: Burns A, Levy R, ed. Dementia. London: Chapman and Hall, 1994:721-37
13. Bergeron C, Pollanen M. Lewy bodies in Alzheimer disease - one or two diseases? Alzheimer Dis Assoc Disord 1989;3:197-204
14. Lennox G, Lowe JS, Godwin-Austen RB, Landon M, Mayer RJ. Diffuse Lewy body disease. An important differential diagnosis in dementia with extrapyramidal features. Prog Clin Biol Res 1989;317:121-30
15. Fischer P, Berner P. Clinical and epidemiological aspects of dementia in the elderly. J Neural Transm Suppl 1991;33:39-48
16. Gearing M, Olson DA, Watts RL, Mirra SS. Progressive supranuclear palsy: Neuropathologic and clinical heterogeneity. Neurology 1994;44:1015-24
17. Drake ME Jr. The association of motor neuron disease and Alzheimer-type dementia. Am J Med Sci 1984;287:26-27
18. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-44
19. Roth M, Huppert FA, Tym E, Mountjoy CQ. CAMDEX. The Cambridge Examination for Mental Disorders in the Elderly. Cambridge: Cambridge University Press, 1988
20. Nagy Zs, Esiri MM, Jobst KA, et al. Relative roles of plaques and tangles in the dementia of Alzheimer's disease: Correlations using three sets of neuropathological criteria. Dementia 1995;6:21-31
21. Mirra SS, Heyman A, McKeel D, et al. The consortium to establish a registry for Alzheimer's disease (CERAD). Part II. Standardisation of the neuropathologic assessment of Alzheimer's disease. Neurology 1991;41:479-86
22. Arriagada PV, Growdon JH, Hedley-Whyte ET, Hyman BT. Neurofibrillary tangles but not senile plaques parallel duration and seventy of Alzheimer's disease. Neurology 1992;42:631-39
23. McKee AC, Kosik KS, Kowall NW. Neuritic pathology and dementia in Alzheimer's disease. Ann Neurol 1991;30:156-65
24. Hardy J, Allsop D. Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol Sci 1991;12:383-88
25. Selkoe DJ. Alzheimer's disease: A central role for amyloid. J Neuropathol Exp Neurol 1994;53:438-47
26. Mann DM, Esiri MM. The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome. J Neurol Sci 1989;89:169-79
27. Crystal H, Dickson D, Fuld P, et al. Clinico-pathologic studies in dementia: Nondemented subjects with pathologically confirmed Alzheimer's disease. Neurology 1988;38:1682-87
28. Katzman R, Terry R, DeTeresa R, et al. Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques. Ann Neurol 1988;23:138-44
29. Hansen L, Salmon D, Galasko D, et al. The Lewy body variant of Alzheimer's disease: A clinical and pathologic entity. Neurology 1990;40:1-8
30. Hansen LA, Musliah E, Galasko D, Terry RD. Plaque-only Alzheimer disease is usually the lewy body variant, and vice versa. J Neuropathol Exp Neurol 1993;52:648-54
31. Delaere P, He Y, Fayet G, Duyckaerts C, Hauw JJ. Beta A4 deposits are constant in the brain of the oldest old: An immunocytochemical study of 20 French centenarians. Neurobiol Aging 1993;14:191-94
32. Mizutani T, Shimada H. Neuropathological background of twenty-seven centenarian brains. J Neurol Sci 1992;108:168-77
33. del Ser T, Bermejo F, Portera A, Arredondo JM, Bouras C, Constantinidis J. Vascular dementia. A clinicopathological study. J Neurol Sci 1990;96:1-17
34. Dwork AJ, Susser ES, Waniek J, Keilp D, Liu D, Kaufman M, Prohovnik I. Relationship of senile degeneration to cognitive impairment in schizophrenia. J Neuropathol Exp Neurol 1996;55:610