Degenerative and vascular lesions of the brain have synergistic effects in dementia of the elderly

Acta Neuropathologica

Volumn 103, Issue 5, 2002, Pages 481-487

  Zekry, Dina ^a   Duyckaerts, Charles ^a   Moulias, Robert ^b   Belmin, Jöel ^c   Geoffre, Caroline ^b   Herrmann, François ^d   Hauw, Jean Jacques ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b HÔPITAL CHARLES FOIX   (France)

^c Hopital Rene Muret Bigottini   (France)

^d GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Alzheimer's disease; Mixed dementia; Morphometry; Multiple infarct dementia; Neuropathology

Indexed keywords

AMYLOID BETA PROTEIN;

AGED; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; BRAIN INFARCTION; CEREBROVASCULAR DISEASE; COGNITIVE DEFECT; CONTROLLED STUDY; CORRELATION ANALYSIS; DEGENERATIVE DISEASE; DISEASE CLASSIFICATION; DISEASE SEVERITY; FEMALE; FRONTAL CORTEX; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PSYCHOMETRY; SENILE DEMENTIA; SENILE PLAQUE; STANDARDIZATION; TEMPORAL CORTEX;

AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; CEREBRAL ARTERIES; CEREBRAL CORTEX; CEREBRAL INFARCTION; DEMENTIA, VASCULAR; DISEASE PROGRESSION; HIPPOCAMPUS; HUMANS; INTRACRANIAL ARTERIOSCLEROSIS; MICROCIRCULATION; NEUROFIBRILLARY TANGLES; NEURONS; PROSPECTIVE STUDIES; PYRAMIDAL CELLS; SENILE PLAQUES;

EID: 0036938669     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-001-0493-5     Document Type: Article

References (41)

1. American Psychiatric Association (1980) Diagnostic and statistical manual of mental disorders, 3rd edn. American Psychiatric Association Washington
2. Barclay L, Zemcov A, Blass JP (1985) Survival in Alzheimer's disease and vascular dementia. Neurology 35:834-840
3. Benton AL (1960) Manuel pour l'application du test de rétention visuelle. Centre de Psychologie appliquée, Paris
4. Boller F, Lopez OL, Moossy J (1989) Diagnosis of dementia: clinicopathologic correlations. Neurology 39:76-79
5. Bowler J, Hachinski VC (1998) Vascular dementia. In: Ginsberg MD, Bogousslavsky J (eds) Cerebrovascular disease: pathophysiology, diagnosis and management, vol 2. Blackwell Science, Massachusetts, pp 1126-1144
6. Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82:239-259
7. Brodmann K (1909) Vergleichende Lokalisationlehre der Grosshirnrinde in ihren Prinzipen dargestellt auf Grund des Zellenbaues. J A Barth, Leipzig
8. Chui HC, Victoroff JI, Margolin D, Jagust W, Shankle R, Katzman R (1992) Criteria for the diagnosis of ischemic vascular dementia proposed by the State of California Alzheimer's Disease Diagnostic and Treatment Centers. Neurology 42:473-480
9. Cohen CI, Araujo L, Guerrier R, Henry KA (1997) "Mixed dementia": adequate or antiquated? A critical review. Am J Geriatr Psychiatry 5:279-283
10. Cummings JL, Benson DF (1989) Dementia: a clinical approach. Butterworth-Heinemann, Boston
11. Del Ser T, Bermejo F, Portera A, Arredondo JM, Bouras C, Constantinidis J (1990) Vascular dementia: a clinicopathological study. J Neurol Sci 96:1-17
12. Delay J, Brion S (1962) Les démences tardives. Masson, Paris
13. Dickson DW, Davies P, Bevona C, Van Hoeven KH, Factor SM, Grober E, Aronson MK, Crystal HA (1994) Hippocampal sclerosis: a common pathological feature of dementia in very old (≥80 years of age) humans. Acta Neuropathol 88:212-221
14. Ebly EM, Parhad IM, Hogan DB, Fung TS (1994) Prevalence and types of dementia in the very old: results from the Canadian Study of Health and Aging. Neurology 44:1593-1600
15. Erkinjuntti T, Haltia M, Palo J, Sulkava R, Paetau A (1988) Accuracy of the clinical diagnosis of vascular dementia: a prospective clinical and post-mortem neuropathological study. J Neurol Neurosurg Psychiatry 51:1037-1044
16. Erkinjuntti T (1988) Differential diagnosis between Alzheimer's disease and vascular dementia - evaluation of common clinical methods. Acta Neurol Scand 76:433-442
17. Esiri MM, Nagy Z, Smith MZ, Barnetson L, Smith AD (1999) Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease. Lancet 364:919-920
18. Folstein MF, Folstein SE, MacHugh PR (1975) Mini Mental State: a practical method for grading the cognitive state of patients for the clinician. J Pychiatr Res 12:189-198
19. Fratiglioni L, Forsell Y, Torres HA, Winblad B (1994) Severity of dementia and institutionalization in the elderly: prevalence data from an urban area in Sweden. Neuroepidemiology 13:79-88
20. Hamilton M (1967) Development of the rating scale for primary depressive illness. Br J Soc Clin Psychol 6:278-296
21. Jellinger K, Danielczyk W, Fischer P, Gabriel E (1990) Clinicopathological analysis of dementia disorders in the elderly. J Neurol Sci 95:239-258
22. Kaye JA (1998) Diagnostic challenges in dementia. Neurology 51 [Suppl]:S45-S52
23. Kokmen E, Offord KP, Okasaki H (1987) A clinical and autopsy study of dementia in Olmsted Country, Minnesota, 1980-1981. Neurology 37:426-430
24. Kuntzmann F, Ebel M, Strubel D, Berthel M (1983) La dépendance des personnes âgées: validation et intérêt d'une méthode d'évaluation applicable à l'étude des populations institutionnalisées. Méd Hyg 41:1894-1898
25. Lee J-H, Olichney JM, Hansen LA, Hofstetter CR, Thal L (2000) Small concomitant vascular lesions do not influence rates of cognitive decline in patients with Alzheimer's disease. Arch Neurol 57:1474-1479
26. Mendez MF, Mastri AR, Sung JH, Frey WH (1992) Clinically diagnosed Alzheimer disease: neuropathologic findings in 650 cases. Alzheimer Dis Assoc Disord 6:35-43
27. Mirra SS, A Heyman, D McKeel, Sumi SM, Crain BJ, Brownlee LM, Vogel FS, Hughes JP, Belle G van, Berg L, and participating CERAD neuropathologists (1991) The Consortium to Establish a Registry for Alzheimer's disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 41:479-486
28. Mölsä PK, Paljärvi L, Rinne JO, Rinne UK, Säkö E (1985) Validity of clinical diagnosis in dementia: a prospective clinicopathological study. J Neurol Neurosurg Psychiatry 48:1085-1090
29. Nagy Z, Esiri MM, Jobst KA, Morris JH, King EM-F, McDonald B, Joachim C, Litchfield S, Barnetson L, Smith AD (1997) The effects of additional pathology on the cognitive deficit in Alzheimer disease. J Neuropathol Exp Neurol 56:165-170
30. Neuropathology group of the medical research council cognitive function and aged study (MRC CFAS) (2001) Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Lancet 357:169-175
31. Poitrenaud J, Aman D (1978) La batterie D. 48 - vocabulaire. (Réflexions à propos de valeurs obtenues chez des adultes ou jeunes adultes appartenant à des niveaux culturels moyens ou inférieurs). Rev Psychol Appl. 28:261-275
32. Reisberg B, Ferris SH, De Leon MJ, Crook KT (1988) Global Deterioration Scale. Psychopharmacol Bull 24:661-663
33. Rockwood K (1997) Lessons from mixed dementia. Int Psychogeriatr 9:245-249
34. Roman GC, Tatemichi TK, Erkinjuntti T, et al (1993) Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology 43:250-260
35. Signoret JL, Bonvarlet M, Benoit N, Bolgert F, Eustache F, Leger JM (1988) Batterie d'estimation des états démentiels; description et validation. In: Leys D, Petit H (eds) La Maladie d'Alzheimer et ses limites. Masson, Paris, pp 265-270
36. Snowdon DA, Greiner LH, Mortimer JA, Riley KP, Greiner PA, Marksbery WR (1997) Brain infarction and the clinical expression of Alzheimer disease. The Nun Study. JAMA 277: 813-817
37. Todorov AB, Go RCP, Constantinidis J, Elston RC (1975) Specificity of the clinical diagnosis of dementia. J Neurol Sci 26:81-98
38. Tomlinson BE, Blessed G, Roth M (1970) Observations on the brains of demented old people. J Neurol Sci 11:205-242
39. Vinters HV, Ellis WG, Zarow C, Zaias BW, Jagust WJ, Mack WJ, Chui HC (2000) Neuropathologic substrates of ischemic vascular dementia. J Neuropathol Exp Neurol 59:931-945
40. Wechsler D (1970) Manual for the Wechsler adult intelligence scale. The psychological corporation, New York
41. Weibel ER (1980) Stereological methods: practical methods for biological morphometry. Academic Press, New York