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Volumn 4, Issue 4, 2006, Pages 421-442

Quantitative characterization of mitosis-blocked tetraploid cells using high content analysis

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; DNA; F ACTIN; FLUORESCENT DYE; HISTONE H3; NOCODAZOLE; PROTEIN P53; RETINOBLASTOMA PROTEIN; TUBULIN;

EID: 33751232619     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2006.4.421     Document Type: Article
Times cited : (14)

References (50)
  • 1
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • Hartwell LH, Kastan MB: Cell cycle control and cancer. Science 1994;266:1821-1828.
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 2
    • 0031470835 scopus 로고    scopus 로고
    • Checkpoint pathways come of age
    • Nurse P: Checkpoint pathways come of age. Cell 1997;9: 865-867.
    • (1997) Cell , vol.9 , pp. 865-867
    • Nurse, P.1
  • 3
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ: Cancer cell cycles. Science 1996;274:1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 4
    • 0034614334 scopus 로고    scopus 로고
    • A long twentieth century of the cell cycle and beyond
    • Nurse P: A long twentieth century of the cell cycle and beyond. Cell 2000;100:71-78.
    • (2000) Cell , vol.100 , pp. 71-78
    • Nurse, P.1
  • 5
    • 0035754080 scopus 로고    scopus 로고
    • To cycle or not to cycle: A critical decision in cancer
    • Malumbres M, Barbacid M: To cycle or not to cycle: a critical decision in cancer. Nat Rev Cancer 2001;1:222-231.
    • (2001) Nat Rev Cancer , vol.1 , pp. 222-231
    • Malumbres, M.1    Barbacid, M.2
  • 6
    • 0025678371 scopus 로고
    • Cell line-specific differences in the control of cell cycle progression in the absence of mitosis
    • Kung AL, Sherwood SW, Schimke RT: Cell line-specific differences in the control of cell cycle progression in the absence of mitosis. Proc Natl Acad Sci U S A 1990;87: 9553-9557.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 9553-9557
    • Kung, A.L.1    Sherwood, S.W.2    Schimke, R.T.3
  • 8
    • 0029658664 scopus 로고    scopus 로고
    • Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage
    • Minn AJ, Boise LH, Thompson CB: Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage. Genes Dev 1996;10:2621-2631.
    • (1996) Genes Dev , vol.10 , pp. 2621-2631
    • Minn, A.J.1    Boise, L.H.2    Thompson, C.B.3
  • 9
    • 0031931414 scopus 로고    scopus 로고
    • Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
    • Lanni JS, Jacks T: Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Mol Cell Biol 1998;18:1055-1064.
    • (1998) Mol Cell Biol , vol.18 , pp. 1055-1064
    • Lanni, J.S.1    Jacks, T.2
  • 10
    • 0032005132 scopus 로고    scopus 로고
    • p53 and pRb prevent rereplication in response to microtubule inhibitors by mediating a reversible G1 arrest
    • Khan SH, Wahl GM: p53 and pRb prevent rereplication in response to microtubule inhibitors by mediating a reversible G1 arrest. Cancer Res 1998;58:396-401.
    • (1998) Cancer Res , vol.58 , pp. 396-401
    • Khan, S.H.1    Wahl, G.M.2
  • 12
    • 0034036003 scopus 로고    scopus 로고
    • The role of p53 in the response to mitotic spindle damage
    • Meek DW: The role of p53 in the response to mitotic spindle damage. Pathol Biol 2000;48:246-254.
    • (2000) Pathol Biol , vol.48 , pp. 246-254
    • Meek, D.W.1
  • 13
    • 0034767429 scopus 로고    scopus 로고
    • Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1
    • Andreassen PR, Lohez OD, Lacroix FB, Margolis RL: Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1. Mol Biol Cell 2001;12: 1315-1328.
    • (2001) Mol Biol Cell , vol.12 , pp. 1315-1328
    • Andreassen, P.R.1    Lohez, O.D.2    Lacroix, F.B.3    Margolis, R.L.4
  • 15
    • 0035886017 scopus 로고    scopus 로고
    • Neither p21WAF1 nor 14-3-3sigma prevents G2 progression to mitotic catastrophe in human colon carcinoma cells after DNA damage, but p21WAF1 induces stable G1 arrest in resulting tetraploid cells
    • Andreassen PR, Lacroix FB, Lohez OD, Margolis RL: Neither p21WAF1 nor 14-3-3sigma prevents G2 progression to mitotic catastrophe in human colon carcinoma cells after DNA damage, but p21WAF1 induces stable G1 arrest in resulting tetraploid cells. Cancer Res 2001;61:7660-7668.
    • (2001) Cancer Res , vol.61 , pp. 7660-7668
    • Andreassen, P.R.1    Lacroix, F.B.2    Lohez, O.D.3    Margolis, R.L.4
  • 16
    • 0346158531 scopus 로고    scopus 로고
    • High content screening applied to large-scale cell biology
    • Abraham VC, Taylor DL, Haskins JR: High content screening applied to large-scale cell biology. Trends Biotechnol 2004;22:15-22.
    • (2004) Trends Biotechnol , vol.22 , pp. 15-22
    • Abraham, V.C.1    Taylor, D.L.2    Haskins, J.R.3
  • 19
    • 0035164176 scopus 로고    scopus 로고
    • Quantitative analysis of agonist-dependent parathyroid hormone receptor trafficking in whole cells using a functional green fluorescent protein conjugate
    • Conway BR, Minor LK, Xu JZ, D'Andrea MR, Ghosh RN, Demarest KT: Quantitative analysis of agonist-dependent parathyroid hormone receptor trafficking in whole cells using a functional green fluorescent protein conjugate. J Cell Physiol 2001;189:341-355.
    • (2001) J Cell Physiol , vol.189 , pp. 341-355
    • Conway, B.R.1    Minor, L.K.2    Xu, J.Z.3    D'Andrea, M.R.4    Ghosh, R.N.5    Demarest, K.T.6
  • 20
    • 7044227922 scopus 로고    scopus 로고
    • Quantification of the proliferation index of human dermal fibroblast cultures with the ArrayScan high-content screening reader
    • Gasparri F, Mariani M, Sola F, Galvani A: Quantification of the proliferation index of human dermal fibroblast cultures with the ArrayScan high-content screening reader. J Biomol Screen 2004;9:232-243.
    • (2004) J Biomol Screen , vol.9 , pp. 232-243
    • Gasparri, F.1    Mariani, M.2    Sola, F.3    Galvani, A.4
  • 23
    • 24144457709 scopus 로고    scopus 로고
    • Quantitative cell-based high content screening assay for vasopressin receptor agonists using transfluor technology
    • Ghosh RN, DeBiasio R, Hudson CC, Ramer ET, Cowan CL, Oakley RH: Quantitative cell-based high content screening assay for vasopressin receptor agonists using transfluor technology. J Biomol Screen 2005; 10:476-484.
    • (2005) J Biomol Screen , vol.10 , pp. 476-484
    • Ghosh, R.N.1    DeBiasio, R.2    Hudson, C.C.3    Ramer, E.T.4    Cowan, C.L.5    Oakley, R.H.6
  • 24
    • 17044431370 scopus 로고    scopus 로고
    • High-content screening with siRNA optimizes a cell biological approach to drug discovery: Defining the role of P53 activation in the cellular response to anticancer drugs
    • Giuliano KA, Chen YT, Taylor DL: High-content screening with siRNA optimizes a cell biological approach to drug discovery: defining the role of P53 activation in the cellular response to anticancer drugs. J Biomol Screen 2004; 9:557-568.
    • (2004) J Biomol Screen , vol.9 , pp. 557-568
    • Giuliano, K.A.1    Chen, Y.T.2    Taylor, D.L.3
  • 25
    • 4444335279 scopus 로고    scopus 로고
    • Multiparametric evaluation of apoptosis: Effects of standard cytotoxic agents and the cyanoguanidine CHS 828
    • Lovborg H, Nygren P, Larsson R: Multiparametric evaluation of apoptosis: effects of standard cytotoxic agents and the cyanoguanidine CHS 828. Mol Cancer Ther 2004;3:521-526.
    • (2004) Mol Cancer Ther , vol.3 , pp. 521-526
    • Lovborg, H.1    Nygren, P.2    Larsson, R.3
  • 26
    • 16844387091 scopus 로고    scopus 로고
    • A quantitative high-throughput endothelial cell migration assay
    • Mastyugin V, McWhinnie E, Labow M, Buxton F: A quantitative high-throughput endothelial cell migration assay. J Biomol Screen 2004;9:712-718.
    • (2004) J Biomol Screen , vol.9 , pp. 712-718
    • Mastyugin, V.1    McWhinnie, E.2    Labow, M.3    Buxton, F.4
  • 28
    • 10344263915 scopus 로고    scopus 로고
    • Imaging analysis of STAT1 and NF-kappaB translocation in dendritic cells at the single cell level
    • Vakkila J, DeMarco RA, Lotze MT: Imaging analysis of STAT1 and NF-kappaB translocation in dendritic cells at the single cell level. J Immunol Methods 2004;294:123-134.
    • (2004) J Immunol Methods , vol.294 , pp. 123-134
    • Vakkila, J.1    DeMarco, R.A.2    Lotze, M.T.3
  • 29
    • 2942588819 scopus 로고    scopus 로고
    • A scalable high-content cytotoxicity assay insensitive to changes in mitochondrial metabolic activity
    • Vogt A, Kalb EN, Lazo JS: A scalable high-content cytotoxicity assay insensitive to changes in mitochondrial metabolic activity. Oncol Res 2004;14:305-314.
    • (2004) Oncol Res , vol.14 , pp. 305-314
    • Vogt, A.1    Kalb, E.N.2    Lazo, J.S.3
  • 30
    • 21744445484 scopus 로고    scopus 로고
    • Automated classification of individual cellular responses across multiple targets
    • Abraham VC, Samso B, Lapets O, Haskins JR: Automated classification of individual cellular responses across multiple targets. Preclinica 2004;2:349-355.
    • (2004) Preclinica , vol.2 , pp. 349-355
    • Abraham, V.C.1    Samso, B.2    Lapets, O.3    Haskins, J.R.4
  • 31
    • 10244229793 scopus 로고    scopus 로고
    • A quantitative cell-based high-content screening assay for the epidermal growth factor receptor-specific activation of mitogen-activated protein kinase
    • Ghosh RN, Grove L, Lapets O: A quantitative cell-based high-content screening assay for the epidermal growth factor receptor-specific activation of mitogen-activated protein kinase. Assay Drug Dev Technol 2004;2:473-481.
    • (2004) Assay Drug Dev Technol , vol.2 , pp. 473-481
    • Ghosh, R.N.1    Grove, L.2    Lapets, O.3
  • 33
    • 0035045748 scopus 로고    scopus 로고
    • Flow cytometry in analysis of cell cycle and apoptosis
    • Darzynkiewicz Z, Bedner E, Smolewski P: Flow cytometry in analysis of cell cycle and apoptosis. Semin Hematol 2001;38:179-193.
    • (2001) Semin Hematol , vol.38 , pp. 179-193
    • Darzynkiewicz, Z.1    Bedner, E.2    Smolewski, P.3
  • 34
    • 0034919717 scopus 로고    scopus 로고
    • DNA measurement and cell cycle analysis by flow cytometry
    • Nunez R: DNA measurement and cell cycle analysis by flow cytometry. Curr Issues Mol Biol 2001;3:67-70.
    • (2001) Curr Issues Mol Biol , vol.3 , pp. 67-70
    • Nunez, R.1
  • 35
    • 33751228775 scopus 로고    scopus 로고
    • Decoupling retinoblastoma protein dephosphorylation from mitosis
    • Ghosh RN, Grove L: Decoupling retinoblastoma protein dephosphorylation from mitosis. Mol Biol Cell 2003;14 (Suppl):2306.
    • (2003) Mol Biol Cell , vol.14 , Issue.SUPPL. , pp. 2306
    • Ghosh, R.N.1    Grove, L.2
  • 36
    • 0003409574 scopus 로고    scopus 로고
    • Digital Image Processing
    • Prentice Hall, Upper Saddle River, NJ
    • Castleman KR: Digital Image Processing. Prentice Hall, Upper Saddle River, NJ, 1996.
    • (1996)
    • Castleman, K.R.1
  • 37
    • 0030920202 scopus 로고    scopus 로고
    • Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro
    • Vasquez RJ, Howell B, Yvon AM, Wadsworth P, Cassimeris L: Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro. Mol Biol Cell 1997;8:973-985.
    • (1997) Mol Biol Cell , vol.8 , pp. 973-985
    • Vasquez, R.J.1    Howell, B.2    Yvon, A.M.3    Wadsworth, P.4    Cassimeris, L.5
  • 38
    • 0026643589 scopus 로고
    • Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis
    • Jordan MA, Thrower D, Wilson L: Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis. J Cell Sci 1992;102:401-416.
    • (1992) J Cell Sci , vol.102 , pp. 401-416
    • Jordan, M.A.1    Thrower, D.2    Wilson, L.3
  • 39
    • 0031935648 scopus 로고    scopus 로고
    • Control of pRB phosphorylation
    • Mittnacht S: Control of pRB phosphorylation. Curr Opin Genet Dev 1998;8:21-27.
    • (1998) Curr Opin Genet Dev , vol.8 , pp. 21-27
    • Mittnacht, S.1
  • 40
    • 0344671608 scopus 로고    scopus 로고
    • Functions of the retinoblastoma, protein
    • Kaelin WG Jr: Functions of the retinoblastoma, protein. Bioessays 1999;21:950-958.
    • (1999) Bioessays , vol.21 , pp. 950-958
    • Kaelin Jr., W.G.1
  • 42
    • 0037418910 scopus 로고    scopus 로고
    • Mitosis through the microscope: Advances in seeing inside live dividing cells
    • Rieder CL, Khodjakov A: Mitosis through the microscope: advances in seeing inside live dividing cells. Science 2003;300:91-96.
    • (2003) Science , vol.300 , pp. 91-96
    • Rieder, C.L.1    Khodjakov, A.2
  • 45
    • 1242338653 scopus 로고    scopus 로고
    • High-content profiling of drug-drug interactions: Cellular targets involved in the modulation of microtubule drug action by the antifungal ketoconazole
    • Giuliano KA: High-content profiling of drug-drug interactions: cellular targets involved in the modulation of microtubule drug action by the antifungal ketoconazole. J Biomol Screen 2003;8:125-135.
    • (2003) J Biomol Screen , vol.8 , pp. 125-135
    • Giuliano, K.A.1
  • 46
    • 0037832515 scopus 로고    scopus 로고
    • Synthesis and high content cell-based profiling of simplified analogues of the microtubule stabilizer (+)-discodermolide
    • Minguez JM, Giuliano KA, Balachandran R, Madiraju C, Curran DP, Day BW: Synthesis and high content cell-based profiling of simplified analogues of the microtubule stabilizer (+)-discodermolide. Mol Cancer Ther 2002;1:1305-1313.
    • (2002) Mol Cancer Ther , vol.1 , pp. 1305-1313
    • Minguez, J.M.1    Giuliano, K.A.2    Balachandran, R.3    Madiraju, C.4    Curran, D.P.5    Day, B.W.6
  • 47
  • 48
    • 0035827553 scopus 로고    scopus 로고
    • Spatial analysis of key signaling proteins by high-content solid-phase cytometry in Hep3B cells treated with an inhibitor of Cdc25 dual-specificity phosphatases
    • Vogt A, Adachi T, Ducruet AP, Chesebrough J, Nemoto K, Carr BI, Lazo JS: Spatial analysis of key signaling proteins by high-content solid-phase cytometry in Hep3B cells treated with an inhibitor of Cdc25 dual-specificity phosphatases. J Biol Chem 2001;276:20544-20550.
    • (2001) J Biol Chem , vol.276 , pp. 20544-20550
    • Vogt, A.1    Adachi, T.2    Ducruet, A.P.3    Chesebrough, J.4    Nemoto, K.5    Carr, B.I.6    Lazo, J.S.7
  • 49
    • 0041913991 scopus 로고    scopus 로고
    • Cell-active dual specificity phosphatase inhibitors identified by high-content screening
    • Vogt A, Cooley KA, Brisson M, Tarpley MG, Wipf P, Lazo JS: Cell-active dual specificity phosphatase inhibitors identified by high-content screening. Chem Biol 2003;10:733-742.
    • (2003) Chem Biol , vol.10 , pp. 733-742
    • Vogt, A.1    Cooley, K.A.2    Brisson, M.3    Tarpley, M.G.4    Wipf, P.5    Lazo, J.S.6
  • 50
    • 21344451886 scopus 로고    scopus 로고
    • The benzôphenanthridine alkaloid, sanguinarine, is a selective, cell-active inhibitor of mitogen-activated protein kinase phosphatase-1
    • Vogt A, Tamewitz A, Skoko J, Sikorski RP, Giuliano KA, Lazo JS: The benzôphenanthridine alkaloid, sanguinarine, is a selective, cell-active inhibitor of mitogen-activated protein kinase phosphatase-1. J Biol Chem 2005;280: 19078-19086.
    • (2005) J Biol Chem , vol.280 , pp. 19078-19086
    • Vogt, A.1    Tamewitz, A.2    Skoko, J.3    Sikorski, R.P.4    Giuliano, K.A.5    Lazo, J.S.6


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