-
1
-
-
12344261004
-
Overexpression of fatty acid synthase in chemically and hormonally induced hepatocarcinogenesis of the rat
-
Evert M, Schneider-Stock R, Dombrowski F. Overexpression of fatty acid synthase in chemically and hormonally induced hepatocarcinogenesis of the rat. Lab Invest 2005; 85:99-108.
-
(2005)
Lab Invest
, vol.85
, pp. 99-108
-
-
Evert, M.1
Schneider-Stock, R.2
Dombrowski, F.3
-
2
-
-
0027409425
-
Physiologic concentrations of glucose regulate fatty acid synthase activity in HepG2 cells by mediating fatty acid synthase mRNA stability
-
Semenkovich CF, Coleman T, Goforth R. Physiologic concentrations of glucose regulate fatty acid synthase activity in HepG2 cells by mediating fatty acid synthase mRNA stability. J Biol Chem 1993; 268:6961-70.
-
(1993)
J Biol Chem
, vol.268
, pp. 6961-6970
-
-
Semenkovich, C.F.1
Coleman, T.2
Goforth, R.3
-
3
-
-
2542445809
-
Fatty acid synthase: A metabolic oncogene in prostate cancer?
-
Baron A, Migita T, Tang D, Loda M. Fatty acid synthase: A metabolic oncogene in prostate cancer? J Cell Biochem 2004; 91:47-53.
-
(2004)
J Cell Biochem
, vol.91
, pp. 47-53
-
-
Baron, A.1
Migita, T.2
Tang, D.3
Loda, M.4
-
4
-
-
0037258555
-
Fatty acid synthase expression in melanoma
-
Innocenzi D, Alo PL, Balzani A, Sebastiani V, Silipo V, La Torre G, Ricciardi G, Bosman C, Calvieri S. Fatty acid synthase expression in melanoma. J Cutan Pathol 2003; 30:23-8.
-
(2003)
J Cutan Pathol
, vol.30
, pp. 23-28
-
-
Innocenzi, D.1
Alo, P.L.2
Balzani, A.3
Sebastiani, V.4
Silipo, V.5
La Torre, G.6
Ricciardi, G.7
Bosman, C.8
Calvieri, S.9
-
5
-
-
0034002793
-
Fatty-acid synthase and human cancer: New perspectives on its role in tumor biology
-
Kuhajda FP. Fatty-acid synthase and human cancer: New perspectives on its role in tumor biology. Proc Natl Acad Sci USA 2000; 16:202-8.
-
(2000)
Proc Natl Acad Sci USA
, vol.16
, pp. 202-208
-
-
Kuhajda, F.P.1
-
6
-
-
0033386501
-
Immunohistochemical expression of fatty acid synthase, apoptotic-regulating genes, proliferating factors, and ras protein product in colorectal adenomas, carcinomas, and adjacent nonneoplastic mucosa
-
Visca P, Alo PL, Del Nonno F, Botti C, Trombetta G, Marandino F, Filippi S, Di Tondo U, Donnorso RP. Immunohistochemical expression of fatty acid synthase, apoptotic-regulating genes, proliferating factors, and ras protein product in colorectal adenomas, carcinomas, and adjacent nonneoplastic mucosa. Clin Cancer Res 1999; 5:4111-8.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 4111-4118
-
-
Visca, P.1
Alo, P.L.2
Del Nonno, F.3
Botti, C.4
Trombetta, G.5
Marandino, F.6
Filippi, S.7
Di Tondo, U.8
Donnorso, R.P.9
-
7
-
-
0038823867
-
Expression of the lipogenic enzyme fatty acid synthase (FAS) in retinoblastoma and its correlation with tumor aggressiveness
-
Camassei FD, Cozza R, Acquaviva A, Jenkner A, Rava L, Gareri R, Donfrancesco A, Bosman C, Vadala P, Hadjistilianou T, Boldrini R. Expression of the lipogenic enzyme fatty acid synthase (FAS) in retinoblastoma and its correlation with tumor aggressiveness. Invest Ophthalmol Vis Sci 2003; 44:2399-403.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 2399-2403
-
-
Camassei, F.D.1
Cozza, R.2
Acquaviva, A.3
Jenkner, A.4
Rava, L.5
Gareri, R.6
Donfrancesco, A.7
Bosman, C.8
Vadala, P.9
Hadjistilianou, T.10
Boldrini, R.11
-
8
-
-
0038418257
-
RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells
-
De Schrijver E, Brusselmans K, Heyns W, Verhoeven G, Swinnen JV. RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells. Cancer Res 2003; 63:3799-804.
-
(2003)
Cancer Res
, vol.63
, pp. 3799-3804
-
-
De Schrijver, E.1
Brusselmans, K.2
Heyns, W.3
Verhoeven, G.4
Swinnen, J.V.5
-
9
-
-
3242685815
-
Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells
-
Menendez JA, Vellon L, Mehmi I, Oza BP, Ropero S, Colomer R, Lupu R. Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells. Proc Natl Acad Sci USA 2004; 101:10715-20.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10715-10720
-
-
Menendez, J.A.1
Vellon, L.2
Mehmi, I.3
Oza, B.P.4
Ropero, S.5
Colomer, R.6
Lupu, R.7
-
10
-
-
0035866378
-
Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53
-
Li JN, Gorospe M, Chrest FJ, Kumaravel TS, Evans MK, Han WF, Pizer ES. Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53. Cancer Res 2001; 61:1493-9.
-
(2001)
Cancer Res
, vol.61
, pp. 1493-1499
-
-
Li, J.N.1
Gorospe, M.2
Chrest, F.J.3
Kumaravel, T.S.4
Evans, M.K.5
Han, W.F.6
Pizer, E.S.7
-
11
-
-
3142713030
-
A fatty acid synthase blockade induces tumor cell-cycle arrest by down-regulating Skp2
-
Knowles LM, Axelrod F, Browne CD, Smith JW. A fatty acid synthase blockade induces tumor cell-cycle arrest by down-regulating Skp2. J Biol Chem 2004; 279:30540-5.
-
(2004)
J Biol Chem
, vol.279
, pp. 30540-30545
-
-
Knowles, L.M.1
Axelrod, F.2
Browne, C.D.3
Smith, J.W.4
-
12
-
-
12444252156
-
Fatty acid synthase inhibitors are chemopreventive for mammary cancer in neu-N transgenic mice
-
Alli PM, Pinn ML, Jaffee EM, McFadden JM, Kuhajda FP. Fatty acid synthase inhibitors are chemopreventive for mammary cancer in neu-N transgenic mice. Oncogene 2004; 24:39-46.
-
(2004)
Oncogene
, vol.24
, pp. 39-46
-
-
Alli, P.M.1
Pinn, M.L.2
Jaffee, E.M.3
McFadden, J.M.4
Kuhajda, F.P.5
-
13
-
-
13444304479
-
Fatty acid synthase is a potential molecular target for the chemoprevention of breast cancer
-
Lu S, Archer MC. Fatty acid synthase is a potential molecular target for the chemoprevention of breast cancer. Carcinogenesis 2005; 26:153-7.
-
(2005)
Carcinogenesis
, vol.26
, pp. 153-157
-
-
Lu, S.1
Archer, M.C.2
-
14
-
-
11144338721
-
Fatty acid oxidation and control of food intake
-
Leonhardt M, Langhans W. Fatty acid oxidation and control of food intake. Physiol Behav 2004; 83:645-51.
-
(2004)
Physiol Behav
, vol.83
, pp. 645-651
-
-
Leonhardt, M.1
Langhans, W.2
-
15
-
-
0025262417
-
Abnormal structure and expression of p53 gene in human hepatocellular carcinoma
-
Bressac B, Galvin KM, Liang TJ, Isselbacher KJ, Wands JR, Ozturk M. Abnormal structure and expression of p53 gene in human hepatocellular carcinoma. Proc Natl Acad Sci USA 1990; 87:1973-7.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 1973-1977
-
-
Bressac, B.1
Galvin, K.M.2
Liang, T.J.3
Isselbacher, K.J.4
Wands, J.R.5
Ozturk, M.6
-
16
-
-
17344372847
-
Activation of mitogen-activated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinoma
-
Ito Y, Sasaki Y, Horimoto M, Wada S, Tanaka Y, Kasahara A, Ueki T, Hirano T, Yamamoto H, Fujimoto J, Okamoto E, Hayashi N, Hori M. Activation of mitogen-activated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinoma. Hepatology 1998; 27:951-8.
-
(1998)
Hepatology
, vol.27
, pp. 951-958
-
-
Ito, Y.1
Sasaki, Y.2
Horimoto, M.3
Wada, S.4
Tanaka, Y.5
Kasahara, A.6
Ueki, T.7
Hirano, T.8
Yamamoto, H.9
Fujimoto, J.10
Okamoto, E.11
Hayashi, N.12
Hori, M.13
-
17
-
-
0016416490
-
Fatty acid synthase from rabbit mammary gland
-
Dils R, Carey EM. Fatty acid synthase from rabbit mammary gland. Methods Enzymol 1975; 35:74-83.
-
(1975)
Methods Enzymol
, vol.35
, pp. 74-83
-
-
Dils, R.1
Carey, E.M.2
-
18
-
-
0037226462
-
Transcriptome analysis of HER2 reveals a molecular connection to fatty acid synthesis
-
Kumar-Sinha C, Ignatoski KW, Lippman ME, Ethier SP, Chinnaiyan AM. Transcriptome analysis of HER2 reveals a molecular connection to fatty acid synthesis. Cancer Res 2003; 63:132-9.
-
(2003)
Cancer Res
, vol.63
, pp. 132-139
-
-
Kumar-Sinha, C.1
Ignatoski, K.W.2
Lippman, M.E.3
Ethier, S.P.4
Chinnaiyan, A.M.5
-
19
-
-
0037403024
-
Expression of the lipogenic enzyme fatty acid synthase (FAS) as a predictor of poor outcome in nephroblastoma: An interinstitutional study
-
Camassei FD, Jenkner A, Rava L, Bosman C, Francalanci P, Donfrancesco A, Alo PL, Boldrini R. Expression of the lipogenic enzyme fatty acid synthase (FAS) as a predictor of poor outcome in nephroblastoma: An interinstitutional study. Med Pediatr Oncol 2003; 40:302-8.
-
(2003)
Med Pediatr Oncol
, vol.40
, pp. 302-308
-
-
Camassei, F.D.1
Jenkner, A.2
Rava, L.3
Bosman, C.4
Francalanci, P.5
Donfrancesco, A.6
Alo, P.L.7
Boldrini, R.8
-
20
-
-
0031987296
-
p53-dependent cell cycle control: Response to genotoxic stress
-
Schwartz D, Rotter V. p53-dependent cell cycle control: Response to genotoxic stress. Semin Cancer Biol 1998; 8:325-36.
-
(1998)
Semin Cancer Biol
, vol.8
, pp. 325-336
-
-
Schwartz, D.1
Rotter, V.2
-
23
-
-
0031918244
-
Regulation of proliferation-survival decisions during tumor cell hypoxia
-
Schmaltz C, Hardenbergh PH, Wells A, Fisher DE. Regulation of proliferation-survival decisions during tumor cell hypoxia. Mol Cell Biol 1998; 18:2845-54.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2845-2854
-
-
Schmaltz, C.1
Hardenbergh, P.H.2
Wells, A.3
Fisher, D.E.4
-
24
-
-
0030815894
-
Mechanisms of cycloheximide-induced apoptosis in liver cells
-
Alessenko AV, Boikov PYa, Filippova GN, Khrenov AV, Loginov AS, Makarieva ED. Mechanisms of cycloheximide-induced apoptosis in liver cells. FEBS Lett 1997; 416:113-6.
-
(1997)
FEBS Lett
, vol.416
, pp. 113-116
-
-
Alessenko, A.V.1
Boikov, P.Ya.2
Filippova, G.N.3
Khrenov, A.V.4
Loginov, A.S.5
Makarieva, E.D.6
-
25
-
-
12644291915
-
Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: Evidence for the involvement of RNA perturbation
-
Pritchard DM, Watson AJ, Potten CS, Jackman AL, Hickman JA. Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: Evidence for the involvement of RNA perturbation. Proc Natl Acad Sci USA 1997; 94:1795-9.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1795-1799
-
-
Pritchard, D.M.1
Watson, A.J.2
Potten, C.S.3
Jackman, A.L.4
Hickman, J.A.5
-
26
-
-
0032568150
-
Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha
-
An WG, Kanekal M, Simon MC, Maltepe E, Blagosklonny MV, Neckers LM. Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha. Nature 1998; 392:405-8.
-
(1998)
Nature
, vol.392
, pp. 405-408
-
-
An, W.G.1
Kanekal, M.2
Simon, M.C.3
Maltepe, E.4
Blagosklonny, M.V.5
Neckers, L.M.6
-
27
-
-
0034097798
-
MAP kinase pathways activated by stress: The p38 MAPK pathway
-
Obata T, Brown GE, Yaffe MB. MAP kinase pathways activated by stress: The p38 MAPK pathway. Crit Care Med 2000; 28:N67-77.
-
(2000)
Crit Care Med
, vol.28
-
-
Obata, T.1
Brown, G.E.2
Yaffe, M.B.3
-
28
-
-
3142720785
-
Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB
-
Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB. Int J Oncol 2004; 24:591-608.
-
(2004)
Int J Oncol
, vol.24
, pp. 591-608
-
-
Menendez, J.A.1
Mehmi, I.2
Atlas, E.3
Colomer, R.4
Lupu, R.5
-
29
-
-
0035735754
-
Role of mitogen-activated protein kinases in the response of tumor cells to chemotherapy
-
Fan M, Chambers TC. Role of mitogen-activated protein kinases in the response of tumor cells to chemotherapy. Drug Resist Updat 2001; 4:253-67.
-
(2001)
Drug Resist Updat
, vol.4
, pp. 253-267
-
-
Fan, M.1
Chambers, T.C.2
-
30
-
-
0035992286
-
Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition
-
MacKeigan JP, Taxman DJ, Hunter D, Earp IIIrd HS, Graves LM, Ting JP. Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition. Clin Cancer Res 2002; 8:2091-9.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2091-2099
-
-
MacKeigan, J.P.1
Taxman, D.J.2
Hunter, D.3
Earp III, H.S.4
Graves, L.M.5
Ting, J.P.6
-
31
-
-
17644394237
-
Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity
-
Menendez JA, Vellon L, Colomer R, Lupu R. Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity. Int J Cancer 2005; 115(1):19-35.
-
(2005)
Int J Cancer
, vol.115
, Issue.1
, pp. 19-35
-
-
Menendez, J.A.1
Vellon, L.2
Colomer, R.3
Lupu, R.4
-
32
-
-
1442274808
-
p38 MAP kinase: A convergence point in cancer therapy
-
Olson JM, Hallahan AR. p38 MAP kinase: A convergence point in cancer therapy. Trends Mol Med 2004; 10:125-9.
-
(2004)
Trends Mol Med
, vol.10
, pp. 125-129
-
-
Olson, J.M.1
Hallahan, A.R.2
-
33
-
-
0032197092
-
The cell cycle: A review
-
Schafer KA. The cell cycle: A review. Vet Pathol 1998; 35:461-78.
-
(1998)
Vet Pathol
, vol.35
, pp. 461-478
-
-
Schafer, K.A.1
-
35
-
-
0031987296
-
p53-dependent cell cycle control: Response to genotoxic stress
-
Schwartz D, Rotter V. p53-dependent cell cycle control: Response to genotoxic stress. Semin Cancer Biol 1998; 8:325-36.
-
(1998)
Semin Cancer Biol
, vol.8
, pp. 325-336
-
-
Schwartz, D.1
Rotter, V.2
-
36
-
-
4444240191
-
The functional interactions between the p53 and MAPK signaling pathways
-
Wu GS. The functional interactions between the p53 and MAPK signaling pathways. Cancer Biol Ther 2004; 3:156-61.
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 156-161
-
-
Wu, G.S.1
|