Probing the active site tightness of DNA polymerase in subangstrom increments

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 44, 2005, Pages 15803-15808

  Kim, Tae Woo ^a   Delaney, James C ^b   Essigmann, John M ^b   Kool, Eric T ^a  

^a STANFORD UNIVERSITY   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Fidelity; Mutagenesis; Replication bypass; Steady state kinetics

Indexed keywords

ADENINE; BACTERIAL DNA; BROMINE; CHLORINE; DICHLOROTOLUENE; DNA DIRECTED DNA POLYMERASE BETA; FLUORINE; HYDROGEN; IODINE; NUCLEIC ACID BASE; OXYGEN; THYMINE; TOLUENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ATOM; BASE PAIRING; DNA REPLICATION; ENZYME ACTIVE SITE; ENZYME KINETICS; ESCHERICHIA COLI; EVOLUTION; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STEADY STATE; STEREOCHEMISTRY;

BASE PAIRING; BINDING SITES; DNA POLYMERASE I; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI PROTEINS; KINETICS; MOLECULAR PROBES; MUTAGENESIS; THYMINE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 27644567193     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0505113102     Document Type: Article

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