The optically determined size of exo/endo cycling vesicle pool correlates with the quantal content at the neuromuscular junction of Drosophila larvae

Journal of Neuroscience

Volumn 19, Issue 5, 1999, Pages 1557-1565

  Kuromi, Hiroshi ^a   Kidokoro, Yoshiaki ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Cyclosporin A; Drosophila larva; FM1 43; Forskolin; Neuromuscular junction; Quantal content; Synaptic vesicle pools

Indexed keywords

ARTICLE; DROSOPHILA; ELECTROPHYSIOLOGY; ENDOCYTOSIS; EXOCYTOSIS; NEUROMUSCULAR SYNAPSE; NONHUMAN; PRIORITY JOURNAL; SYNAPSE VESICLE; SYNAPTIC POTENTIAL; SYNAPTIC TRANSMISSION;

EID: 0033103353     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-05-01557.1999     Document Type: Article

References (35)

1. Bernstein BW, Bamhurg JR (1989) Cycling of actin assembly in syrtaptosomes and neurotransmitter release. Neuron 3:257-265.
2. Betz WJ, Henkel AW (1994) Okudaic acid disrupts clusters of synaptic vesicles in frog motor nerve terminals. J Cell Biol 124:843-854.
3. Chang H, Ciani S, Kidokoro Y (1994) Ion permeation properties of the glutamate receptor channel in cultured embryonic Drosophila myotubes. J Physiol (Lond) 479:1-16.
4. Cooper JA (1987) Effects of cytochalasin and phalloidin on actin. J Cell Biol 105:1473-1478.
5. Davis GW, DiAntonio A, Petersen SA, Goodman CS (1998) Postsynaptic PKA controls quantal size and reveals a retrograde signal that regulates presynaptic transmitter release in Drosophila. Neuron 20:305-315.
6. Dixon D, Atwood HL (1989) Adenylate cyclase system is essential for long-term facilitation at the crayfish neuromuscular junction. J Neurosci 9:4246-4252.
7. Dobrunz LE, Stevens CF (1997) Heterogeneity of release probability, facilitation, and depletion at central synapses. Neuron 18:995-1008.
8. Ewing AG, Bigelow JC, Wightman RM ( 1983) Direct in vivo monitoring of dopaminc release from two striatal compartments in the rat. Science 221:169-171.
9. Furukawa K, Fu W, Li Y, Witke W, Kwiatkowski DJ, Mattson MP (1997) The actin-scvering protein gelsolin modulates calcium channel and NMDA receptor activities and vulnerability to excitotoxicity in hippocampal neurons. J Neurosci 17:8178-8186.
10. Gingrieh KJ, Byrnc JH (1985) Simulation of synaptic depression, posttetanic potentiation. and presynaptic facilitation of synaptic potentials from sensory neurons mediating gill-withdrawal reflex in Aplysia. J Neurophysiol 53:652-669.
11. Goldberg AL, Singer JJ (1969) Evidence for a role of cyclic AMP in neuromuscular transmission. Proc Natl Acad Sci USA 64:134-141.
12. Hirokawa N, Sobuc K, Kanda K, Harada A, Yorifuji H (1989) The cytoskcletal architecture of the presynaptic terminal and molecular structure of synapsin 1. J Cell Biol 108:111-126.
13. Jan LY, Jan JN (1976) Properties of the larval neuromuscular junction in Drosophila melanogaster. J Physiol (Lond) 262:189-214.
14. Kandel ER, Schwartz JH (1982) Molecular biology of learning; modulation of transmitter release. Science 218:433-443.
15. Koenig JH, Kosaka T, Ikeda K (1989) The relationship between the number of synaptic vesicles and the amount of transmitter released. J Neurosci 9:1937-1942.
16. Kuromi H, Kidokoro Y ( 1998a) Two distinct pools of synaptic vesicles in single presynaptic boutons in a temperature-sensitive Drosophila mutant, shibire. Neuron 20:917-925.
17. Kuromi H, Kidokoro Y (1998b) The relationships between the size of readily releasable pool of synaptic vesicles and the quantal content of synaptic potentials. Neurosci Res 22:598.
18. Kuromi H, Yoshihara M, Kidokoro Y (1997) An inhibitory role of calcineurin in endocytosis of synaptic vesicles at nerve terminals of Drosophila larvae. Neurosci Res 27:101-113.
19. Martin AR (1955) A further study of the statistical composition of the end-plate potential. J Physiol (Lond) 130:114-122.
20. Miller TM, Heuser JE (1984) Endocytosis of synaptic vesicle membrane at the frog neuromuscular junction. J Cell Biol 98:685-698.
21. 2+ microdomains: New tools for understanding their roles in neurotransmitter release. Neuron 20:389-399.
22. Pierihone VA, Shupliakov O, Brodin L. Hilfiker-Rothenfluh S, Czernik AJ, Greengard P (1995) Distinct pools of synaptic vesicles in neurotransmiltcr release. Nature 375:493-497.
23. Poodry CA, Edgar L (1979) Reversible alternations in the neuromuscular junctions of Drosophila melanogaster bearing a temperature-sensitive mutation, shibire. J Cell Biol 81:520-527.
24. Ryan TA, Reuter H, Wendland B, Schweizer FE, Tsien RW, Smith SJ (1993) The kinetics of synaptic vesicle recycling measured at single presynaptic boutons. Neuron 11:713-724.
25. Ryan TA, Li L, Chin L-S, Greengard P, Smith SJ (1996) Synaptic vesicle recycling in synapsin 1 knock-out mice. J Cell Biol 134:1219-1227.
26. Schikorski T, Stevens CF (1997) Quantitative ultrastructural analysis of hippocampal excitatory synapses. J Neurosci 17:5858-5867.
27. Seamon K, Daly J (1983) Forskolin, cyclic AMP and cellular physiology. Trends Pharmacol Sci 4:120-123.
28. Smith SJ (1988) Neuronal cytomechanics: the actin-based motility of growth cones. Science 242:708-715.
29. Stevens CF, Tsujimoto T (1995) Estimates for the pool size of releasable quanta at a single central synapse and for the time required to refill the pool. Proc Natl Acad Sci USA 92:846-849.
30. Stewari BA, Atwood HL, Renger JJ, Wang J, Wu C-F (1994) Improved stability of Drosophila larval neuromuscular preparations in haemolymph-like physiological solutions. J Comp Physiol 175:179-191.
31. Trudeau L-E, Emery DG, Haydon PG (1996) Direct modulation of the secretory machinery underlies PKA-dependent synaptic facilitation in hippocampal neurons. Neuron 17:789-797.
32. Von Gersdorff H, Vardi E, Matthews G, Sterling P (1996) Evidence that vesicles on the synaptic ribbon of retinal bipolar neurons can be rapidly released. Neuron 116:1221-1227.
33. Zhang D, Kuromi H, Kidokoro Y (1998) Synaptic transmission at the Drosophila neuromuscular junction: effects of metabotropic glutamate receptor activation. Jpn J Physiol, in press.
34. Zhong Y, Wu C-F (1990) Altered synaptic plasticity in Drosophila memory mutants with a defective cAMP cascade. Science 251:198-201.
35. Zimmermann H, Whiltaker VP (1977) Morphological and biochemical heterogeneity of cholinergic synaptic vesicles. Nature 267:633-635.