Novel strategies to delineate matrix metalloproteinase (MMP)-substrate relationships and identify targets to block MMP activity

Mini-Reviews in Medicinal Chemistry

Volumn 6, Issue 11, 2006, Pages 1243-1248

  Lindsey, M L ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Extracellular matrix; Fibrosis; Matrix metalloproteinases; Mechanism based inhibition; MMP inhibitors; Proteomics; Remodeling

Indexed keywords

DOXYCYCLINE HYCLATE; GELATINASE A; HYDROXAMIC ACID DERIVATIVE; INTERSTITIAL COLLAGENASE; MALTOL; MARIMASTAT; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; PYRONE DERIVATIVE; STROMELYSIN;

ARTHRALGIA; CLINICAL TRIAL; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; EXTRACELLULAR MATRIX; HEART MUSCLE FIBROSIS; HUMAN; KIDNEY FIBROSIS; LUNG FIBROSIS; MASS SPECTROMETRY; MYALGIA; PROTEOMICS; QUANTITATIVE ANALYSIS; REVIEW;

ENZYME INHIBITORS; EXTRACELLULAR MATRIX; HUMANS; MALE; MATRIX METALLOPROTEINASES; PROTEOMICS; SUBSTRATE SPECIFICITY;

EID: 33750714030     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/138955706778742777     Document Type: Review

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