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Journal of the American Chemical Society

Volumn 122, Issue 40, 2000, Pages 9648-9654

Structure-based design of a novel, potent, and selective inhibitor for MMP-13 utilizing NMR spectroscopy and computer-aided molecular design

(8) Chen, J M a Nelson, F C b Levin, J I b Mobilio, D b Moy, J F b Nilakantan, R b Zask, A b Powers, R b

a PFIZER INC (United States)

b WYETH RESEARCH (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CL 82198; COLLAGENASE 3; COLLAGENASE INHIBITOR; GELATINASE B; UNCLASSIFIED DRUG; WAY 152177; WAY 159062; WAY 159063; WAY 170523;

ARTICLE; COMPUTER AIDED DESIGN; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

EID: 0034638377 PISSN: 00027863 EISSN: None Source Type: Journal
DOI: 10.1021/ja001547g Document Type: Article

Times cited : (112)

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