메뉴 건너뛰기




Volumn 47, Issue 10, 2006, Pages 4614-4623

Sustained versus transient ERK1/2 signaling underlies the anti- and proapoptotic effects of oxidative stress in human RPE cells

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ENZYME INHIBITOR; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 11; MITOGEN ACTIVATED PROTEIN KINASE 12; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN ANTIBODY; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE 1; TERT BUTYL HYDROPEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 10; MITOGEN ACTIVATED PROTEIN KINASE P38;

EID: 33750584426     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.06-0297     Document Type: Article
Times cited : (86)

References (39)
  • 1
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson GL, Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science. 2002;298:1911-1912.
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 2
    • 0034997845 scopus 로고    scopus 로고
    • Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
    • Pearson G, Robinson F, Beers Gibson T, et al. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev. 2001;22:153-183.
    • (2001) Endocr Rev , vol.22 , pp. 153-183
    • Pearson, G.1    Robinson, F.2    Beers Gibson, T.3
  • 3
    • 0242361581 scopus 로고    scopus 로고
    • Transcriptional regulation by the MAP kinase signaling cascades
    • Yang SH, Sharrocks AD, Whitmarsh AJ. Transcriptional regulation by the MAP kinase signaling cascades. Gene. 2003;320:3-21.
    • (2003) Gene , vol.320 , pp. 3-21
    • Yang, S.H.1    Sharrocks, A.D.2    Whitmarsh, A.J.3
  • 4
    • 0242551370 scopus 로고    scopus 로고
    • Chronic activation of ERK and neurodegenerative diseases
    • Colucci-D'Amato L, Perrone-Capano C, di Porzio U. Chronic activation of ERK and neurodegenerative diseases. Bioessays. 2003;25:1085-1095.
    • (2003) Bioessays , vol.25 , pp. 1085-1095
    • Colucci-D'Amato, L.1    Perrone-Capano, C.2    di Porzio, U.3
  • 5
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall CJ. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell. 1995;80:179-185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 6
    • 0034765383 scopus 로고    scopus 로고
    • Spatiotemporal regulation of the p42/p44 MAPK pathway
    • Volmat V. Pouyssegur J. Spatiotemporal regulation of the p42/p44 MAPK pathway. Biol Cell. 2001;93:71-79.
    • (2001) Biol Cell , vol.93 , pp. 71-79
    • Volmat, V.1    Pouyssegur, J.2
  • 8
    • 0034881019 scopus 로고    scopus 로고
    • Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals
    • Ballif BA, Blenis J. Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals. Cell Growth Differ. 2001;12:397-408.
    • (2001) Cell Growth Differ , vol.12 , pp. 397-408
    • Ballif, B.A.1    Blenis, J.2
  • 9
    • 0035984912 scopus 로고    scopus 로고
    • ROS, stress-activated kinases and stress signaling in cancer
    • Benhar M, Engelberg D, Levitzki A. ROS, stress-activated kinases and stress signaling in cancer. EMBO Rep. 2002;3:420-425.
    • (2002) EMBO Rep , vol.3 , pp. 420-425
    • Benhar, M.1    Engelberg, D.2    Levitzki, A.3
  • 10
    • 0033516947 scopus 로고    scopus 로고
    • Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation
    • Perry G, Roder H, Nunomura A, et al. Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation. Neuroreport. 1999;10:2411-2415.
    • (1999) Neuroreport , vol.10 , pp. 2411-2415
    • Perry, G.1    Roder, H.2    Nunomura, A.3
  • 11
    • 18944389722 scopus 로고    scopus 로고
    • Tissue plasminogen activator mediates amyloid-induced neurotoxicity via Erk1/2 activation
    • Medina MG, Ledesma MD, Dominguez JE, et al. Tissue plasminogen activator mediates amyloid-induced neurotoxicity via Erk1/2 activation. EMBO J. 2005;24:1706-1716.
    • (2005) EMBO J , vol.24 , pp. 1706-1716
    • Medina, M.G.1    Ledesma, M.D.2    Dominguez, J.E.3
  • 12
    • 1442331932 scopus 로고    scopus 로고
    • Activation of JNK in sensory neurons protects against sensory neuron cell death in diabetes and on exposure to glucose/oxidative stress in vitro
    • Price SA, Hounsom L, Purves-Tyson TD, Fernyhough P, Tomlinson DR. Activation of JNK in sensory neurons protects against sensory neuron cell death in diabetes and on exposure to glucose/oxidative stress in vitro. Ann NY Acad Sci. 2003;1010:95-99.
    • (2003) Ann NY Acad Sci , vol.1010 , pp. 95-99
    • Price, S.A.1    Hounsom, L.2    Purves-Tyson, T.D.3    Fernyhough, P.4    Tomlinson, D.R.5
  • 13
    • 0037375044 scopus 로고    scopus 로고
    • Oxidative-stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: A possible mechanism for RPE aging and age-related macular degeneration
    • Liang FQ, Godley BF. Oxidative-stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration. Exp Eye Res. 2003;76:397-403.
    • (2003) Exp Eye Res , vol.76 , pp. 397-403
    • Liang, F.Q.1    Godley, B.F.2
  • 14
    • 0033795036 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of age-related macular degeneration
    • Beatty S, Koh H, Phil M, Henson D, Boulton M. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol. 2000;45:115-134.
    • (2000) Surv Ophthalmol , vol.45 , pp. 115-134
    • Beatty, S.1    Koh, H.2    Phil, M.3    Henson, D.4    Boulton, M.5
  • 15
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature. 2000;408:239-247.
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 16
  • 17
    • 0037334819 scopus 로고    scopus 로고
    • Activation and role of MAP kinase-dependent pathways in retinal pigment epithelium cells: JNK1, P38 kinase, and cell death
    • Hecquet C, Lefevre G, Valtink M, Engelmann K, Mascarelli F. Activation and role of MAP kinase-dependent pathways in retinal pigment epithelium cells: JNK1, P38 kinase, and cell death. Invest Ophthalmol Vis Sci. 2003;44:1320-1329.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 1320-1329
    • Hecquet, C.1    Lefevre, G.2    Valtink, M.3    Engelmann, K.4    Mascarelli, F.5
  • 18
    • 0029872876 scopus 로고    scopus 로고
    • ARPE-19, a human retinal pigment epithelial cell line with differentiated properties
    • Dunn KC, Aotaki-Keen AE, Putkey FR, Hjelmeland LM. ARPE-19, a human retinal pigment epithelial cell line with differentiated properties. Exp Eye Res. 1996;62:155-169.
    • (1996) Exp Eye Res , vol.62 , pp. 155-169
    • Dunn, K.C.1    Aotaki-Keen, A.E.2    Putkey, F.R.3    Hjelmeland, L.M.4
  • 19
    • 0034787989 scopus 로고    scopus 로고
    • Downregulation of differentiation specific gene expression by oxidative stress in ARPE-19 cells
    • Alizadeh M, Wada M, Gelfman CM, Handa JT, Hjelmeland LM. Downregulation of differentiation specific gene expression by oxidative stress in ARPE-19 cells. Invest Ophthalmol Vis Sci. 2001;42:2706-2713.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 2706-2713
    • Alizadeh, M.1    Wada, M.2    Gelfman, C.M.3    Handa, J.T.4    Hjelmeland, L.M.5
  • 20
    • 0037026637 scopus 로고    scopus 로고
    • cAMP inhibits the proliferation of retinal pigmented epithelial cells through the inhibition of ERK1/2 in a PKA-independent manner
    • Hecquet C, Lefevre G, Valtink M. Engelmann K, Mascarelli F. cAMP inhibits the proliferation of retinal pigmented epithelial cells through the inhibition of ERK1/2 in a PKA-independent manner. Oncogene. 2002;21:6101-6112.
    • (2002) Oncogene , vol.21 , pp. 6101-6112
    • Hecquet, C.1    Lefevre, G.2    Valtink, M.3    Engelmann, K.4    Mascarelli, F.5
  • 22
    • 0030886770 scopus 로고    scopus 로고
    • Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats
    • Aikawa R, Komuro I, Yamazaki T, et al. Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats. J Clin Invest. 1997;100:1813-1821.
    • (1997) J Clin Invest , vol.100 , pp. 1813-1821
    • Aikawa, R.1    Komuro, I.2    Yamazaki, T.3
  • 23
    • 0036368596 scopus 로고    scopus 로고
    • Ikeyama S, Kokkonen G, Shack S, Wang XT, Holbrook NJ. Loss in oxidative stress tolerance with aging linked to reduced extracellular signal-regulated kinase and Akt kinase activities. Faseb J. 2002;16:114-116.
    • Ikeyama S, Kokkonen G, Shack S, Wang XT, Holbrook NJ. Loss in oxidative stress tolerance with aging linked to reduced extracellular signal-regulated kinase and Akt kinase activities. Faseb J. 2002;16:114-116.
  • 24
    • 3042739490 scopus 로고    scopus 로고
    • Oxidative stress causes ERK phosphorylation and cell death in cultured retinal pigment epithelium: Prevention of cell death by AG126 and 15-deoxy-delta 12, 14-PGJ2
    • Garg TK, Chang JY. Oxidative stress causes ERK phosphorylation and cell death in cultured retinal pigment epithelium: prevention of cell death by AG126 and 15-deoxy-delta 12, 14-PGJ2. BMC Ophthalmol. 2003;3:5.
    • (2003) BMC Ophthalmol , vol.3 , pp. 5
    • Garg, T.K.1    Chang, J.Y.2
  • 25
    • 0033607259 scopus 로고    scopus 로고
    • MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia
    • Alessandrini A, Namura S, Moskowitz MA, Bonventre JV. MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia. Proc Natl Acad Sci USA. 1999;96:12866-12869.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12866-12869
    • Alessandrini, A.1    Namura, S.2    Moskowitz, M.A.3    Bonventre, J.V.4
  • 26
    • 0035949472 scopus 로고    scopus 로고
    • Intravenous administration of MEK inhibitor UO126 affords brain protection against forebrain ischemia and focal cerebral ischemia
    • Namura S, Iihara K, Takami S, et al. Intravenous administration of MEK inhibitor UO126 affords brain protection against forebrain ischemia and focal cerebral ischemia. Proc Nail Acad Sci USA. 2001;98:11569-11574.
    • (2001) Proc Nail Acad Sci USA , vol.98 , pp. 11569-11574
    • Namura, S.1    Iihara, K.2    Takami, S.3
  • 27
    • 0034903539 scopus 로고    scopus 로고
    • Zn2+-induced ERK activation mediated by reactive oxygen species causes cell death in differentiated PC12 cells
    • Seo SR, Chong SA, Lee SI, et al. Zn2+-induced ERK activation mediated by reactive oxygen species causes cell death in differentiated PC12 cells. J Neurochem. 2001;78:600-610.
    • (2001) J Neurochem , vol.78 , pp. 600-610
    • Seo, S.R.1    Chong, S.A.2    Lee, S.I.3
  • 28
    • 0034697364 scopus 로고    scopus 로고
    • Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and prima cortical neuron cultures
    • Stanciu M, Wang Y, Kentor R, et al. Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and prima cortical neuron cultures. J Biol Chem. 2000;275:12200-12206.
    • (2000) J Biol Chem , vol.275 , pp. 12200-12206
    • Stanciu, M.1    Wang, Y.2    Kentor, R.3
  • 29
    • 0034648063 scopus 로고    scopus 로고
    • Neuroprotection by MAPK/ERK kinase inhibition with UO126 against oxidative stress in a mouse neuronal cell line and nit primar cultured cortical neurons
    • Satoh T, Nakatsuka D, Watanabe Y, Nagata I, Kikuchi H, Namura S. Neuroprotection by MAPK/ERK kinase inhibition with UO126 against oxidative stress in a mouse neuronal cell line and nit primar cultured cortical neurons. Neurosci Lett. 2000;288:163-166.
    • (2000) Neurosci Lett , vol.288 , pp. 163-166
    • Satoh, T.1    Nakatsuka, D.2    Watanabe, Y.3    Nagata, I.4    Kikuchi, H.5    Namura, S.6
  • 30
    • 0033600821 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathway mediates peroxynitrite-induced apoptosis in human dopaminergic neuroblastoma SH-SY5Y cells
    • Oh-hashi K, Maruyama W, Yi H, Takahashi T, Naomi M, Isobe K. Mitogen-activated protein kinase pathway mediates peroxynitrite-induced apoptosis in human dopaminergic neuroblastoma SH-SY5Y cells. Biochem Biophys Res Commun. 1999;263:504-509.
    • (1999) Biochem Biophys Res Commun , vol.263 , pp. 504-509
    • Oh-hashi, K.1    Maruyama, W.2    Yi, H.3    Takahashi, T.4    Naomi, M.5    Isobe, K.6
  • 32
    • 33644698801 scopus 로고    scopus 로고
    • Voloboueva LA, Liu J, Suh JH, Ames BN, Miller SS. (R)-α- lipoic acid protects retinal pigment epithelial cells from oxidative damage. Invest Ophthalmol Vis Sci. 2005;46:4302-4310.
    • Voloboueva LA, Liu J, Suh JH, Ames BN, Miller SS. (R)-α- lipoic acid protects retinal pigment epithelial cells from oxidative damage. Invest Ophthalmol Vis Sci. 2005;46:4302-4310.
  • 33
    • 0242581714 scopus 로고    scopus 로고
    • Oxidative stress in the pathogenesis of experimental mesangial proliferative glomerulonephritis
    • Budisavljevic MN, Hodge L, Barber K, et al. Oxidative stress in the pathogenesis of experimental mesangial proliferative glomerulonephritis. Am J Physiol. 2003;285:F1138-F1148.
    • (2003) Am J Physiol , vol.285
    • Budisavljevic, M.N.1    Hodge, L.2    Barber, K.3
  • 34
    • 3543020265 scopus 로고    scopus 로고
    • Subcellular localization determines the protective effects of activated ERK2 against distinct apoptogenic stimuli in myeloid leukemia cells
    • Ajenjo N, Canon E, Sanchez-Perez I, et al. Subcellular localization determines the protective effects of activated ERK2 against distinct apoptogenic stimuli in myeloid leukemia cells. J Biol Chem. 2004;279:32813-32823.
    • (2004) J Biol Chem , vol.279 , pp. 32813-32823
    • Ajenjo, N.1    Canon, E.2    Sanchez-Perez, I.3
  • 36
    • 14044277677 scopus 로고    scopus 로고
    • Reversible oxidation of ERK-directed protein phosphatases drives oxidative toxicity in neurons
    • Levinthal DJ, Defranco DB. Reversible oxidation of ERK-directed protein phosphatases drives oxidative toxicity in neurons. J Biol Chem. 2005;280:5875-5883.
    • (2005) J Biol Chem , vol.280 , pp. 5875-5883
    • Levinthal, D.J.1    Defranco, D.B.2
  • 37
  • 38
    • 0036899278 scopus 로고    scopus 로고
    • Cytoplasmic aggregates of phosphorylated extracellular signal-regulated protein kinases in Lewy body diseases
    • Zhu JH, Kulich SM, Oury TD, Chu CT. Cytoplasmic aggregates of phosphorylated extracellular signal-regulated protein kinases in Lewy body diseases. Am J Pathol. 2002;161:2087-2098.
    • (2002) Am J Pathol , vol.161 , pp. 2087-2098
    • Zhu, J.H.1    Kulich, S.M.2    Oury, T.D.3    Chu, C.T.4
  • 39
    • 2542492120 scopus 로고    scopus 로고
    • CREB and neurodegeneration
    • Dragunow M. CREB and neurodegeneration. Front Biosci. 2004;9:100-103.
    • (2004) Front Biosci , vol.9 , pp. 100-103
    • Dragunow, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.