Design and synthesis of a novel photoaffinity ligand for the dopamine and serotonin transporters based on 2β-carbomethoxy-3β-biphenyltropane

Journal of Medicinal Chemistry

Volumn 49, Issue 22, 2006, Pages 6621-6625

  Newman, Amy Hauck ^a   Cha, Joo Hwan ^a   Cao, Jianjing ^a   Kopajtic, Theresa ^a   Katz, Jonathan L ^a   Parnas, M Laura ^b   Vaughan, Roxanne ^b   Lever, John R ^c  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^c University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4' AZIDO 3' IODOBIPHENYL 4 YL) 8 METHYL 8 AZABICYCLO[3.2.1]OCTANE 2 CARBOXYLIC ACID METHYL ESTER; DOPAMINE TRANSPORTER; SEROTONIN TRANSPORTER; TROPANE ALKALOID; TROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DOPAMINE RELEASE; DRUG DESIGN; DRUG SYNTHESIS; LIGAND BINDING; MOLECULAR PROBE; PHOTOACTIVATION; PHOTOAFFINITY LABELING; SEROTONIN RELEASE; STILLE REACTION; STRUCTURE ACTIVITY RELATION; SUZUKI REACTION;

COCAINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DRUG DESIGN; INDICATORS AND REAGENTS; IODINE RADIOISOTOPES; LIGANDS; PHOTOAFFINITY LABELS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33750451963     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0603973     Document Type: Article

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