Radioiodinated azide and isothiocyanate derivatives of cocaine for irreversible labeling of dopamine transporters: Synthesis and covalent binding studies

Bioconjugate Chemistry

Volumn 16, Issue 3, 2005, Pages 644-649

  Lever, John R ^a,b,f   Zou, Mu Fa ^c   Parnas, M Laura ^d   Duval, Romain A ^a,b   Wirtz, Sara E ^e   Justice, Joseph B ^e   Vaughan, Roxanne A ^d   Newman, Amy Hauck ^c  

^a UNIVERSITY OF MISSOURI   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^d UNIVERSITY OF NORTH DAKOTA   (United States)

^e EMORY UNIVERSITY   (United States)

^f University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NEUROPHYSIOLOGY; PHASE SEPARATION; SODIUM AZIDE;

BINDING STUDIES; BINDING-SITES; COVALENT BINDING; DOPAMINE TRANSPORTERS; IODINE-125; ISOTHIOCYANATES; LABELINGS; PHOTOLABELING; RADIOIODINATION; RADIOLIGANDS;

AMINES;

ANILINE DERIVATIVE; AZIDE; COCAINE; DOPAMINE TRANSPORTER; ISOTHIOCYANIC ACID DERIVATIVE; N [4 (3 [IODINE 125]IODO 4 AZIDOPHENYL)BUTYL] 2 BETA CARBOMETHOXY 3 BETA (4 CHLOROPHENYL)TROPANE; N [4 (3 [IODINE 125]IODO 4 ISOTHIOCYANOPHENYL)BUTYL] 2 BETA CARBOMETHOXY 3BETA (4 CHLOROPHENYL)TROPANE; RADIOLIGAND; SODIUM AZIDE; TROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; COVALENT BOND; DIAZOTIZATION; DRUG CONJUGATION; IODINATION; PHOTOAFFINITY LABELING; RADIOACTIVITY; RADIOCHEMISTRY; RADIOIMMUNOPRECIPITATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID PHASE EXTRACTION; SYNTHESIS;

EID: 18844430585     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc0497214     Document Type: Article

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