3'-Chloro-3α-(diphenylmethoxy)tropane but not 4'-chloro-3α- (diphenylmethoxy)tropane produces a cocaine-like behavioral profile

Journal of Medicinal Chemistry

Volumn 40, Issue 6, 1997, Pages 851-857

  Kline, Richard H ^a   Izenwasser, Sari ^a   Katz, Jonathan L ^a   Joseph, David B ^b   Bowen, Wayne D ^b   Newman, Amy Hauck ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3' CHLORO 3ALPHA (DIPHENYLMETHOXY)TROPANE; 3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; BENZATROPINE; COCAINE; DOPAMINE TRANSPORTER; DOPAMINE UPTAKE INHIBITOR; MUSCARINIC M1 RECEPTOR; NORADRENALIN; SEROTONIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CAUDATE NUCLEUS; CONTROLLED STUDY; DOPAMINE UPTAKE; DRUG BINDING; DRUG DEPENDENCE TREATMENT; DRUG DISCRIMINATION; DRUG EFFECT; DRUG POTENCY; INTRAPERITONEAL DRUG ADMINISTRATION; LOCOMOTION; MALE; MOUSE; NONHUMAN; PUTAMEN; RAT; RECEPTOR AFFINITY; REINFORCEMENT;

ANIMALS; BENZTROPINE; BINDING, COMPETITIVE; CARRIER PROTEINS; COCAINE; DISCRIMINATION (PSYCHOLOGY); DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR STRUCTURE; MOTOR ACTIVITY; NEOSTRIATUM; NERVE TISSUE PROTEINS; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, MUSCARINIC; TROPANES;

EID: 0030997211     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950782k     Document Type: Article

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