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Volumn 281, Issue 4, 2006, Pages 2012-2023
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Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants
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Author keywords
[No Author keywords available]
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Indexed keywords
BIOLOGICAL MEMBRANES;
CADMIUM;
METAL ANALYSIS;
HUMAN SEROTONIN TRANSPORTERS;
METHYLENEDIOXYMETHAMPHETAMINES;
RACEMIC CITALOPRAMS;
TIANEPTINES;
PROTEINS;
3,4 METHYLENEDIOXYMETHAMPHETAMINE;
3BETA (4 IODOPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER;
5 METHOXYINDOLETRYPTAMINE;
AMITRIPTYLINE;
ANTIDEPRESSANT AGENT;
CADMIUM;
CITALOPRAM;
CLOMIPRAMINE;
COCAINE;
CYSTEINE;
DOPAMINE 1 RECEPTOR STIMULATING AGENT;
FLUOXETINE;
MAZINDOL;
NISOXETINE;
NOMIFENSENE;
NOMIFENSINE;
NORADRENALIN;
PAROXETINE;
PROTEIN ILE 172;
PROTEIN TYR 95;
SEROTONIN;
SEROTONIN TRANSPORTER;
SEROTONIN UPTAKE INHIBITOR;
SERTRALINE;
TIANEPTINE;
TYRAMINE;
UNCLASSIFIED DRUG;
ADRENERGIC RECEPTOR AFFECTING AGENT;
DOPAMINE UPTAKE INHIBITOR;
DRUG DERIVATIVE;
ISOLEUCINE;
METHIONINE;
RADIOPHARMACEUTICAL AGENT;
SEROTONIN RECEPTOR;
TYROSINE;
ARTICLE;
CHROMOSOME SUBSTITUTION;
DROSOPHILA;
DRUG ANTAGONISM;
DRUG MECHANISM;
DRUG SELECTIVITY;
ENANTIOMER;
ENZYME SUBSTRATE COMPLEX;
GENE TRANSLOCATION;
HUMAN;
HUMAN CELL;
MINIMUM INHIBITORY CONCENTRATION;
MOLECULAR RECOGNITION;
MUTATION;
PHOTOAFFINITY LABELING;
PRIORITY JOURNAL;
PROTEIN INTERACTION;
RACEMIC MIXTURE;
RESIDUE ANALYSIS;
SITE DIRECTED MUTAGENESIS;
AMINO ACID SEQUENCE;
ANIMAL;
BINDING COMPETITION;
BINDING SITE;
CELL LINE;
CELL MEMBRANE;
CELL STRAIN;
CHEMICAL MODEL;
CHEMISTRY;
ENZYME SPECIFICITY;
HELA CELL;
IMMUNOPRECIPITATION;
KINETICS;
METABOLISM;
MOLECULAR GENETICS;
MOUSE;
PROTEIN BINDING;
PROTEIN TERTIARY STRUCTURE;
PROTEIN TRANSPORT;
SPECIES DIFFERENCE;
STEREOISOMERISM;
WESTERN BLOTTING;
ADRENERGIC UPTAKE INHIBITORS;
AMINO ACID SEQUENCE;
ANIMALS;
ANTIDEPRESSIVE AGENTS;
BINDING SITES;
BINDING, COMPETITIVE;
BLOTTING, WESTERN;
CADMIUM;
CELL LINE;
CELL MEMBRANE;
CITALOPRAM;
CLOMIPRAMINE;
COCAINE;
CYSTEINE;
DOPAMINE UPTAKE INHIBITORS;
FLUOXETINE;
HELA CELLS;
HUMANS;
IMMUNOPRECIPITATION;
ISOLEUCINE;
KINETICS;
LLC-PK1 CELLS;
MAZINDOL;
METHIONINE;
MICE;
MODELS, CHEMICAL;
MOLECULAR SEQUENCE DATA;
MUTATION;
N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE;
NOMIFENSINE;
PROTEIN BINDING;
PROTEIN STRUCTURE, TERTIARY;
PROTEIN TRANSPORT;
RADIOPHARMACEUTICALS;
RECEPTORS, SEROTONIN;
SEROTONIN;
SEROTONIN UPTAKE INHIBITORS;
SPECIES SPECIFICITY;
STEREOISOMERISM;
SUBSTRATE SPECIFICITY;
TYROSINE;
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EID: 33644856545
PISSN: 00219258
EISSN: 1083351X
Source Type: Journal
DOI: 10.1074/jbc.M505055200 Document Type: Article |
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Times cited : (154)
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References (36)
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