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Volumn 22, Issue 6, 2006, Pages 599-606

Gastroduodenal mucosal defense

Author keywords

Annexin 1; Antioxidants; Esophagus; Ghrelin; Helicobacter pylori; Reactive oxygen species

Indexed keywords

ALENDRONIC ACID; ANETHOLE; ANTIOXIDANT; ASTAXANTHIN; BISPHOSPHONIC ACID DERIVATIVE; CARNITINE; D 002; DA 9601; DEXAMETHASONE; GHRELIN; GROWTH HORMONE; HEXARELIN; MONTELUKAST; NAPROXEN; NIGELLA SATIVA EXTRACT; NITRONAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PLANT EXTRACT; REBAMIPIDE; ROFECOXIB; UNCLASSIFIED DRUG;

EID: 33750378814     PISSN: 02671379     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mog.0000245540.87784.75     Document Type: Review
Times cited : (35)

References (66)
  • 1
    • 0035258047 scopus 로고    scopus 로고
    • Gastroduodenal mucosal alkaline secretion and mucosal protection
    • Flemström G, Isenberg JI. Gastroduodenal mucosal alkaline secretion and mucosal protection. News Physiol Sci 2001; 16:23-28.
    • (2001) News Physiol Sci , vol.16 , pp. 23-28
    • Flemström, G.1    Isenberg, J.I.2
  • 2
    • 0035667074 scopus 로고    scopus 로고
    • Cellular bicarbonate protects rat duodenal mucosa from acid-induced injury
    • Akiba Y, Furukawa O, Guth PH, et al. Cellular bicarbonate protects rat duodenal mucosa from acid-induced injury. J Clin Invest 2001; 108:1807-1816.
    • (2001) J Clin Invest , vol.108 , pp. 1807-1816
    • Akiba, Y.1    Furukawa, O.2    Guth, P.H.3
  • 3
    • 0035037927 scopus 로고    scopus 로고
    • Role of reactive oxygen metabolites in aspirin-induced gastric damage in humans: Gastroprotection by vitamin C
    • Pohle T, Brzozowski T, Becker JC, et al. Role of reactive oxygen metabolites in aspirin-induced gastric damage in humans: gastroprotection by vitamin C. Aliment Pharmacol Ther 2001; 15:677-687.
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 677-687
    • Pohle, T.1    Brzozowski, T.2    Becker, J.C.3
  • 4
    • 0023900998 scopus 로고
    • Neutrophil-mediated mucosal injury: Role of reactive oxygen metabolites
    • Grisham MB, Granger DN. Neutrophil-mediated mucosal injury: role of reactive oxygen metabolites. Dig Dis Sci 1988; 33:6S-15S.
    • (1988) Dig Dis Sci , vol.33
    • Grisham, M.B.1    Granger, D.N.2
  • 5
    • 0032893048 scopus 로고    scopus 로고
    • Role of antioxidant defenses against ethanol-induced damage in cultured rat gastric epithelial cells
    • Hiraishi H, Shimada T, Ivey KJ, Terano A. Role of antioxidant defenses against ethanol-induced damage in cultured rat gastric epithelial cells. J Pharmacol Exp Ther 1999; 289:103-109.
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 103-109
    • Hiraishi, H.1    Shimada, T.2    Ivey, K.J.3    Terano, A.4
  • 7
    • 23344432659 scopus 로고    scopus 로고
    • Cellular mucosal defense during Helicobacter pylori infection: A review of the role of glutathione and the oxidative pentose pathway
    • Matthews GM, Butler RN. Cellular mucosal defense during Helicobacter pylori infection: a review of the role of glutathione and the oxidative pentose pathway. Helicobacter 2005; 10:298-306.
    • (2005) Helicobacter , vol.10 , pp. 298-306
    • Matthews, G.M.1    Butler, R.N.2
  • 8
    • 0031001835 scopus 로고    scopus 로고
    • Hydroxyl radical is the major causative factor in stress-induced gastric ulceration
    • Das D, Bandyopadhyay D, Bhattacharjee M, Banerjee RK. Hydroxyl radical is the major causative factor in stress-induced gastric ulceration. Free Radic Biol Med 1997; 23:8-18.
    • (1997) Free Radic Biol Med , vol.23 , pp. 8-18
    • Das, D.1    Bandyopadhyay, D.2    Bhattacharjee, M.3    Banerjee, R.K.4
  • 9
    • 33644921214 scopus 로고    scopus 로고
    • Novel mechanisms in functional dyspepsia
    • Choung RS, Talley NJ. Novel mechanisms in functional dyspepsia. World J Gastroenterol 2006; 12:673-677. An excellent recent editorial addressing the pathophysiology of functional dyspepsia, covering genetic factors, motility disturbances, infectious agents, and psychosocial abnormalities.
    • (2006) World J Gastroenterol , vol.12 , pp. 673-677
    • Choung, R.S.1    Talley, N.J.2
  • 10
    • 33645023779 scopus 로고    scopus 로고
    • Dyspeptic symptoms associated with hypersensitivity to gastric distension induced by duodenal acidification
    • Lee KJ, Kim JH, Cho SW. Dyspeptic symptoms associated with hypersensitivity to gastric distension induced by duodenal acidification. J Gastroenterol Hepatol 2006; 21:515-520. Although functional dyspepsia is traditionally associated with motility disturbances, the authors tested the hypothesis that duodenal acidification lowers the threshold for duodenal distension. Their data supported their hypothesis that luminal acid sensitizes duodenal mechanoreception.
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 515-520
    • Lee, K.J.1    Kim, J.H.2    Cho, S.W.3
  • 11
    • 4544388553 scopus 로고    scopus 로고
    • A pilot study on duodenal acid exposure and its relationship to symptoms in functional dyspepsia with prominent nausea
    • Lee KJ, Demarchi B, Demedts I, et al. A pilot study on duodenal acid exposure and its relationship to symptoms in functional dyspepsia with prominent nausea. Am J Gastroenterol 2004; 99:1765-1773.
    • (2004) Am J Gastroenterol , vol.99 , pp. 1765-1773
    • Lee, K.J.1    Demarchi, B.2    Demedts, I.3
  • 12
    • 0029112971 scopus 로고
    • Chemosensitive afferent nerves in the regulation of gastric blood flow and protection
    • Holzer P. Chemosensitive afferent nerves in the regulation of gastric blood flow and protection. Adv Exp Med Biol 1995; 371B:891-895.
    • (1995) Adv Exp Med Biol , vol.371 B , pp. 891-895
    • Holzer, P.1
  • 13
    • 0345059362 scopus 로고    scopus 로고
    • Regulation of intracellular pH and blood flow in rat duodenal epithelium in vivo
    • Akiba Y, Kaunitz JD. Regulation of intracellular pH and blood flow in rat duodenal epithelium in vivo. Am J Physiol Gastrointest Liver Physiol 1999; 276:G293-G302.
    • (1999) Am J Physiol Gastrointest Liver Physiol , vol.276
    • Akiba, Y.1    Kaunitz, J.D.2
  • 14
    • 33744940067 scopus 로고    scopus 로고
    • 2 in rat duodenum
    • ••]) is the first study to examine the role of ecto-carbonic anhydrases on duodenal acid absorption, with implications on mucosal defense and acid-sensing. This is also the first detailed study of duodenal carbonic anhydrase isoform expression.
    • (2006) Gastroenterology , vol.131 , pp. 142-152
    • Akiba, Y.1    Ghayouri, S.2    Takeuchi, T.3
  • 16
    • 33644603970 scopus 로고    scopus 로고
    • Capsaicin receptor (TRPV1) and nonerosive reflux disease
    • Bhat YM, Bielefeldt K. Capsaicin receptor (TRPV1) and nonerosive reflux disease. Eur J Gastroenterol Hepatol 2006; 18:263-270. TRPV1 is strongly implicated as a subepithelial acid sensor in esophagus, possibly playing a role in heartburn, establishing an important clinical correlate.
    • (2006) Eur J Gastroenterol Hepatol , vol.18 , pp. 263-270
    • Bhat, Y.M.1    Bielefeldt, K.2
  • 17
    • 0037900877 scopus 로고    scopus 로고
    • Direct measurement of acid permeation into rat oesophagus
    • Tanaka S, Chu S, Hirokawa M, et al. Direct measurement of acid permeation into rat oesophagus. Gut 2003; 52:775-783.
    • (2003) Gut , vol.52 , pp. 775-783
    • Tanaka, S.1    Chu, S.2    Hirokawa, M.3
  • 18
    • 27744478564 scopus 로고    scopus 로고
    • Immunohistochemical distribution of vanilloid receptor, calcitonin-gene related peptide and substance P in gastrointestinal mucosa of patients with different gastrointestinal disorders
    • Domotor A, Peidl Z, Vincze A, et al. Immunohistochemical distribution of vanilloid receptor, calcitonin-gene related peptide and substance P in gastrointestinal mucosa of patients with different gastrointestinal disorders. Inflammopharmacology 2005; 13:161-177. Survey of the afferent elements implicated in clinical luminal acid sensing.
    • (2005) Inflammopharmacology , vol.13 , pp. 161-177
    • Domotor, A.1    Peidl, Z.2    Vincze, A.3
  • 20
    • 24344471810 scopus 로고    scopus 로고
    • Distribution of the vanilloid (capsaicin) receptor type 1 in the human stomach
    • Faussone-Pellegrini MS, Taddei A, Bizzoco E, et al. Distribution of the vanilloid (capsaicin) receptor type 1 in the human stomach. Histochem Cell Biol 2005; 124:61-68. Using three antibodies, the authors immunolocalized TRPV1 in rat stomach to the parietal cells and submucosal neuronal structures. Surprisingly, TRPV1 appeared to be present near mitochondria, where the authors hypothesized that it could play a role in the regulation of acid secretion.
    • (2005) Histochem Cell Biol , vol.124 , pp. 61-68
    • Faussone-Pellegrini, M.S.1    Taddei, A.2    Bizzoco, E.3
  • 21
    • 25644433559 scopus 로고    scopus 로고
    • Mechanisms underlying capsaicin-stimulated secretion in the stomach: Comparison with mucosal acidification
    • Aihara E, Hayashi M, Sasaki Y, et al. Mechanisms underlying capsaicin-stimulated secretion in the stomach: comparison with mucosal acidification. J Pharmacol Exp Ther 2005; 315:423-432.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 423-432
    • Aihara, E.1    Hayashi, M.2    Sasaki, Y.3
  • 22
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y, et al. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999; 402:656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3
  • 23
    • 19444379510 scopus 로고    scopus 로고
    • Distribution of ghrelin-immunoreactive cells in human gastric mucosa: Comparison with that of parietal cells
    • Tanaka-Shintani M, Watanabe M. Distribution of ghrelin-immunoreactive cells in human gastric mucosa: comparison with that of parietal cells. J Gastroenterol 2005; 40:345-349.
    • (2005) J Gastroenterol , vol.40 , pp. 345-349
    • Tanaka-Shintani, M.1    Watanabe, M.2
  • 24
    • 3242749843 scopus 로고    scopus 로고
    • Ghrelin inhibits leptin- And activation-induced proinflammatory cytokine expression by human monocytes and T cells
    • Dixit VD, Schaffer EM, Pyle RS, et al. Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells. J Clin Invest 2004; 114:57-66.
    • (2004) J Clin Invest , vol.114 , pp. 57-66
    • Dixit, V.D.1    Schaffer, E.M.2    Pyle, R.S.3
  • 25
    • 21044453885 scopus 로고    scopus 로고
    • Circulating ghrelin levels in patients with various upper gastrointestinal diseases
    • Isomoto H, Ueno H, Nishi Y, et al. Circulating ghrelin levels in patients with various upper gastrointestinal diseases. Dig Dis Sci 2005; 50:833-838.
    • (2005) Dig Dis Sci , vol.50 , pp. 833-838
    • Isomoto, H.1    Ueno, H.2    Nishi, Y.3
  • 26
    • 21344438630 scopus 로고    scopus 로고
    • The relationship between plasma and gastric ghrelin levels and strain diversity in Helicobacter pylori virulence
    • Isomoto H, Nishi Y, Ohnita K, et al. The relationship between plasma and gastric ghrelin levels and strain diversity in Helicobacter pylori virulence. Am J Gastroenterol 2005; 100:1425-1427.
    • (2005) Am J Gastroenterol , vol.100 , pp. 1425-1427
    • Isomoto, H.1    Nishi, Y.2    Ohnita, K.3
  • 27
    • 17144402257 scopus 로고    scopus 로고
    • Impact of Helicobacter pylori infection on ghrelin and various neuroendocrine hormones in plasma
    • Isomoto H, Ueno H, Nishi Y, et al. Impact of Helicobacter pylori infection on ghrelin and various neuroendocrine hormones in plasma. World J Gastroenterol 2005; 11:1644-1648.
    • (2005) World J Gastroenterol , vol.11 , pp. 1644-1648
    • Isomoto, H.1    Ueno, H.2    Nishi, Y.3
  • 28
    • 25644434341 scopus 로고    scopus 로고
    • Impact of Helicobacter pylori infection on gastric and plasma ghrelin dynamics in humans
    • Isomoto H, Ueno H, Saenko VA, et al. Impact of Helicobacter pylori infection on gastric and plasma ghrelin dynamics in humans. Am J Gastroenterol 2005; 100:1711-1720.
    • (2005) Am J Gastroenterol , vol.100 , pp. 1711-1720
    • Isomoto, H.1    Ueno, H.2    Saenko, V.A.3
  • 29
    • 0037225643 scopus 로고    scopus 로고
    • Ghrelin protects against ethanol-induced gastric ulcers in rats: Studies on the mechanisms of action
    • Sibilia V, Rindi G, Pagani F, et al. Ghrelin protects against ethanol-induced gastric ulcers in rats: studies on the mechanisms of action. Endocrinology 2003; 144:353-359.
    • (2003) Endocrinology , vol.144 , pp. 353-359
    • Sibilia, V.1    Rindi, G.2    Pagani, F.3
  • 31
    • 29644442884 scopus 로고    scopus 로고
    • Ghrelin against alendronate-induced gastric damage in rats
    • Iseri SO, Sener G, Yuksel M, et al. Ghrelin against alendronate-induced gastric damage in rats. J Endocrinol 2005; 187:399-406. Ghrelin treatment reversed effects of alendronate on rat gastric mucosa, including significant gastric damage, increased myeloperoxidase activity, collagen content, malondialdehyde, and luminal levels, and decreased glutathione levels.
    • (2005) J Endocrinol , vol.187 , pp. 399-406
    • Iseri, S.O.1    Sener, G.2    Yuksel, M.3
  • 32
    • 9644278248 scopus 로고    scopus 로고
    • Effects of hexarelin against acid-independent and acid-dependent ulcerogens in the rat
    • Sibilia V, Torsello A, Pagani F, et al. Effects of hexarelin against acid-independent and acid-dependent ulcerogens in the rat. Peptides 2004; 25:2163-2170.
    • (2004) Peptides , vol.25 , pp. 2163-2170
    • Sibilia, V.1    Torsello, A.2    Pagani, F.3
  • 33
    • 24044532851 scopus 로고    scopus 로고
    • Changes in reducing power profile of gastric juice in patients with active duodenal ulcer
    • Ligumsky M, Klar A, Siguencia J, et al. Changes in reducing power profile of gastric juice in patients with active duodenal ulcer. Biomed Pharmacother 2005; 59:345-350.
    • (2005) Biomed Pharmacother , vol.59 , pp. 345-350
    • Ligumsky, M.1    Klar, A.2    Siguencia, J.3
  • 34
    • 20544468365 scopus 로고    scopus 로고
    • Lipid-soluble and water-soluble antioxidant activities of the avian intestinal mucosa at different sites along the intestinal tract
    • McLean JA, Karadas F, Surai PF, et al. Lipid-soluble and water-soluble antioxidant activities of the avian intestinal mucosa at different sites along the intestinal tract. Comp Biochem Physiol B Biochem Mol Biol 2005; 141:366-372.
    • (2005) Comp Biochem Physiol B Biochem Mol Biol , vol.141 , pp. 366-372
    • McLean, J.A.1    Karadas, F.2    Surai, P.F.3
  • 35
    • 33748609696 scopus 로고    scopus 로고
    • Effects of L-carnitine on neutrophil-mediated ischemia-reperfusion injury in rat stomach
    • (epub ahead of print)
    • Derin N, Agac A, Bayram Z, et al. Effects of L-carnitine on neutrophil-mediated ischemia-reperfusion injury in rat stomach. Cell Biochem Funct 2005 (epub ahead of print). L-Carnitine treatment prior to ischemia significantly reduced both gastric injury and myeloperoxidase activity, a marker of neutrophil accumulation.
    • (2005) Cell Biochem Funct
    • Derin, N.1    Agac, A.2    Bayram, Z.3
  • 36
    • 24744433565 scopus 로고    scopus 로고
    • L-carnitine inhibits ethanol-induced gastric mucosal injury in rats
    • Dokmeci D, Akpolat M, Aydogdu N, et al. L-carnitine inhibits ethanol-induced gastric mucosal injury in rats. Pharmacol Rep 2005; 57:481-488.
    • (2005) Pharmacol Rep , vol.57 , pp. 481-488
    • Dokmeci, D.1    Akpolat, M.2    Aydogdu, N.3
  • 38
    • 0025828195 scopus 로고
    • Nonsteroidal anti-inflammatory drugs and peptic ulcer disease
    • Soll AH, Weinstein WM, Kurata J, McCarthy D. Nonsteroidal anti-inflammatory drugs and peptic ulcer disease. Ann Intern Med 1991; 114:307-319.
    • (1991) Ann Intern Med , vol.114 , pp. 307-319
    • Soll, A.H.1    Weinstein, W.M.2    Kurata, J.3    McCarthy, D.4
  • 39
    • 22744437646 scopus 로고    scopus 로고
    • Direct gas measurements indicate that the novel cyclooxygenase inhibitor AZD3582 is an effective nitric oxide donor in vivo
    • Adding LC, Agvald P, Andersson LI, et al. Direct gas measurements indicate that the novel cyclooxygenase inhibitor AZD3582 is an effective nitric oxide donor in vivo. Br J Pharmacol 2005; 145:679-687.
    • (2005) Br J Pharmacol , vol.145 , pp. 679-687
    • Adding, L.C.1    Agvald, P.2    Andersson, L.I.3
  • 40
    • 17644403756 scopus 로고    scopus 로고
    • AZD3582 increases heme oxygenase-1 expression and antioxidant activity in vascular endothelial and gastric mucosal cells
    • Berndt G, Grosser N, Hoogstraate J, Schroder H. AZD3582 increases heme oxygenase-1 expression and antioxidant activity in vascular endothelial and gastric mucosal cells. Eur J Pharm Sci 2005; 25:229-235. AZD3582 incubated with human endothelial cells increased expression of heme oxygenase-1 mRNA and protein whereas naproxen and rofecoxib did not. The heme oxygenase-1 metabolite bilirubin suppressed NADPH-dependent oxidative stress.
    • (2005) Eur J Pharm Sci , vol.25 , pp. 229-235
    • Berndt, G.1    Grosser, N.2    Hoogstraate, J.3    Schroder, H.4
  • 41
    • 29144446030 scopus 로고    scopus 로고
    • Comparison of the COX-inhibiting nitric oxide donator AZD3582 and rofecoxib in treating the signs and symptoms of osteoarthritis of the knee
    • Schnitzer TJ, Kivitz AJ, Lipetz RS, et al. Comparison of the COX-inhibiting nitric oxide donator AZD3582 and rofecoxib in treating the signs and symptoms of osteoarthritis of the knee. Arthritis Rheum 2005; 53:827-837.
    • (2005) Arthritis Rheum , vol.53 , pp. 827-837
    • Schnitzer, T.J.1    Kivitz, A.J.2    Lipetz, R.S.3
  • 42
    • 33644588856 scopus 로고    scopus 로고
    • Dose-effect comparisons of the CINOD AZD3582 and naproxen on upper gastrointestinal tract mucosal injury in healthy subjects
    • Wilder-Smith CH, Jonzon B, Fornstedt-Wallin B, et al. Dose-effect comparisons of the CINOD AZD3582 and naproxen on upper gastrointestinal tract mucosal injury in healthy subjects. Scand J Gastroenterol 2006; 41:264-273. Healthy volunteers given AZD3582 had significantly lower incidences of gastroduodenal toxicity compared with equimolar doses of naproxen.
    • (2006) Scand J Gastroenterol , vol.41 , pp. 264-273
    • Wilder-Smith, C.H.1    Jonzon, B.2    Fornstedt-Wallin, B.3
  • 43
    • 14144252695 scopus 로고    scopus 로고
    • A randomised, placebo controlled, comparative trial of the gastrointestinal safety and efficacy of AZD3582 versus naproxen in osteoarthritis
    • Lohmander LS, McKeith D, Svensson O, et al. A randomised, placebo controlled, comparative trial of the gastrointestinal safety and efficacy of AZD3582 versus naproxen in osteoarthritis. Ann Rheum Dis 2005; 64:449-456.
    • (2005) Ann Rheum Dis , vol.64 , pp. 449-456
    • Lohmander, L.S.1    McKeith, D.2    Svensson, O.3
  • 44
    • 25644432016 scopus 로고    scopus 로고
    • Rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial RGM-1 cells
    • Nagano Y, Matsui H, Muramatsu M, et al. Rebamipide significantly inhibits indomethacin-induced mitochondrial damage, lipid peroxidation, and apoptosis in gastric epithelial RGM-1 cells. Dig Dis Sci 2005; 50 (suppl 1):S76-S83. Rebamipide protects against indomethacin-induced damage by promoting mitochondrial membrane stability in gastric epithelial cells.
    • (2005) Dig Dis Sci , vol.50 , Issue.SUPPL. 1
    • Nagano, Y.1    Matsui, H.2    Muramatsu, M.3
  • 45
    • 25644458376 scopus 로고    scopus 로고
    • Rebamipide reduces indomethacin-induced gastric injury in mice via down-regulation of ICAM-1 expression
    • Hiratsuka T, Futagami S, Shindo T, et al. Rebamipide reduces indomethacin-induced gastric injury in mice via down-regulation of ICAM-1 expression. Dig Dis Sci 2005; 50 (suppl 1):S84-S89. Rebamipide downregulates intercellular adhesion molecule-1, which is a key molecule involved in neutrophil activation, thus protecting against indomethacin-induced gastric injury.
    • (2005) Dig Dis Sci , vol.50 , Issue.SUPPL. 1
    • Hiratsuka, T.1    Futagami, S.2    Shindo, T.3
  • 46
    • 25644445252 scopus 로고    scopus 로고
    • Rebamipide, a gastro-protective drug, inhibits indomethacin-induced apoptosis in cultured rat gastric mucosal cells: Association with the inhibition of growth arrest and DNA damage-induced 45 alpha expression
    • Naito Y, Kajikawa H, Mizushima K, et al. Rebamipide, a gastro-protective drug, inhibits indomethacin-induced apoptosis in cultured rat gastric mucosal cells: association with the inhibition of growth arrest and DNA damage-induced 45 alpha expression. Dig Dis Sci 2005; 50 (suppl 1):S104-S112.
    • (2005) Dig Dis Sci , vol.50 , Issue.SUPPL. 1
    • Naito, Y.1    Kajikawa, H.2    Mizushima, K.3
  • 47
    • 25644453503 scopus 로고    scopus 로고
    • Prevention by rebamipide of acute reflux esophagitis in rats
    • Katada K, Yoshida N, Isozaki Y, et al. Prevention by rebamipide of acute reflux esophagitis in rats. Dig Dis Sci 2005; 50 (suppl 1):S97-S103. Rebamipide is useful in the prevention and treatment of reflux esophagitis through its antioxidant, antineutrophil, and anticytokine effects.
    • (2005) Dig Dis Sci , vol.50 , Issue.SUPPL. 1
    • Katada, K.1    Yoshida, N.2    Isozaki, Y.3
  • 48
    • 25644448093 scopus 로고    scopus 로고
    • Rebamipide decreases the susceptibility of gastric mucosa to acid-induced injury in rats by inhibiting neutrophil activation
    • Harada N, Okajima K, Liu W. Rebamipide decreases the susceptibility of gastric mucosa to acid-induced injury in rats by inhibiting neutrophil activation. Dig Dis Sci 2005; 50 (suppl 1):S56-S62.
    • (2005) Dig Dis Sci , vol.50 , Issue.SUPPL. 1
    • Harada, N.1    Okajima, K.2    Liu, W.3
  • 49
    • 25644432760 scopus 로고    scopus 로고
    • Rebamipide reduces recurrence of experimental gastric ulcers: Role of free radicals and neutrophils
    • Sakurai K, Osaka T, Yamasaki K. Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils. Dig Dis Sci 2005; 50 (suppl 1):S90-S96. Rebamipide prevented the delayed effects of neutrophil accumulation and free-radical damage in acetic-acid-induced gastric ulcers at 60, 100, and 140 days, effectively preventing the recurrence of ulcers.
    • (2005) Dig Dis Sci , vol.50 , Issue.SUPPL. 1
    • Sakurai, K.1    Osaka, T.2    Yamasaki, K.3
  • 50
    • 0020858787 scopus 로고
    • Protective effects of prostaglandins against gastric mucosal damage: Current knowledge and proposed mechanisms
    • Miller TA. Protective effects of prostaglandins against gastric mucosal damage: current knowledge and proposed mechanisms. Am J Physiol Gastrointest Liver Physiol 1983; 245:G601-G623.
    • (1983) Am J Physiol Gastrointest Liver Physiol , vol.245
    • Miller, T.A.1
  • 51
    • 25644456769 scopus 로고    scopus 로고
    • Gastro-protective agent rebamipide induces cyclooxygenase-2 (COX-2) in gastric epithelial cells
    • Murata H, Yabe Y, Tsuji S, et al. Gastro-protective agent rebamipide induces cyclooxygenase-2 (COX-2) in gastric epithelial cells. Dig Dis Sci 2005; 50 (suppl 1):S70-S75.
    • (2005) Dig Dis Sci , vol.50 , Issue.SUPPL. 1
    • Murata, H.1    Yabe, Y.2    Tsuji, S.3
  • 52
    • 25644439916 scopus 로고    scopus 로고
    • Rebamipide reduces delay in gastric ulcer healing in cyclooxygenase-2- deficient mice
    • Watanabe T, Higuchi K, Taira K, et al. Rebamipide reduces delay in gastric ulcer healing in cyclooxygenase-2-deficient mice. Dig Dis Sci 2005; 50 (suppl 1):S63-S69.
    • (2005) Dig Dis Sci , vol.50 , Issue.SUPPL. 1
    • Watanabe, T.1    Higuchi, K.2    Taira, K.3
  • 53
    • 22144464871 scopus 로고    scopus 로고
    • Rebamipide inhibits gastric cancer growth by targeting survivin and Aurora-B
    • Tarnawski A, Pai R, Chiou SK, et al. Rebamipide inhibits gastric cancer growth by targeting survivin and Aurora-B. Biochem Biophys Res Commun 2005; 19:207-212.
    • (2005) Biochem Biophys Res Commun , vol.19 , pp. 207-212
    • Tarnawski, A.1    Pai, R.2    Chiou, S.K.3
  • 54
    • 27544493208 scopus 로고    scopus 로고
    • Survivin, a potential biomarker in the development of Barrett's adenocarcinoma
    • Vallböhmer D, Peters JH, Oh D, et al. Survivin, a potential biomarker in the development of Barrett's adenocarcinoma. Surgery 2005; 138:701-706.
    • (2005) Surgery , vol.138 , pp. 701-706
    • Vallböhmer, D.1    Peters, J.H.2    Oh, D.3
  • 55
    • 23944490198 scopus 로고    scopus 로고
    • Suppressive effect of astaxanthin isolated from the Xanthophyllomyces dendrorhous mutant on ethanol-induced gastric mucosal injury in rats
    • Kim JH, Choi SK, Choi SY, et al. Suppressive effect of astaxanthin isolated from the Xanthophyllomyces dendrorhous mutant on ethanol-induced gastric mucosal injury in rats. Biosci Biotechnol Biochem 2005; 69:1300-1305.
    • (2005) Biosci Biotechnol Biochem , vol.69 , pp. 1300-1305
    • Kim, J.H.1    Choi, S.K.2    Choi, S.Y.3
  • 56
    • 18844430871 scopus 로고    scopus 로고
    • Protective effect of astaxanthin on naproxen-induced gastric antral ulceration in rats
    • Kim JH, Kim YS, Song GG, et al. Protective effect of astaxanthin on naproxen-induced gastric antral ulceration in rats. Eur J Pharmacol 2005; 514:53-59.
    • (2005) Eur J Pharmacol , vol.514 , pp. 53-59
    • Kim, J.H.1    Kim, Y.S.2    Song, G.G.3
  • 57
    • 31144458385 scopus 로고    scopus 로고
    • Increased susceptibility of ethanol-treated gastric mucosa to naproxen and its inhibition by DA-9601, an Artemisia asiatica extract
    • Oh TY, Ahn GJ, Choi SM, et al. Increased susceptibility of ethanol-treated gastric mucosa to naproxen and its inhibition by DA-9601, an Artemisia asiatica extract. World J Gastroenterol 2005; 11:7450-7456.
    • (2005) World J Gastroenterol , vol.11 , pp. 7450-7456
    • Oh, T.Y.1    Ahn, G.J.2    Choi, S.M.3
  • 58
    • 18144401657 scopus 로고    scopus 로고
    • Therapeutic effect of D-002 (abexol) on gastric ulcer induced experimentally in rats
    • Molina V, Carbajal D, Arruzazabala L, Mas R. Therapeutic effect of D-002 (abexol) on gastric ulcer induced experimentally in rats. J Med Food 2005; 8:59-62.
    • (2005) J Med Food , vol.8 , pp. 59-62
    • Molina, V.1    Carbajal, D.2    Arruzazabala, L.3    Mas, R.4
  • 59
    • 20344379930 scopus 로고    scopus 로고
    • Synthesis and antioxidant, anti-inflammatory and gastroprotector activities of anethole and related compounds
    • Freire RS, Morais SM, Catunda-Junior FE, Pinheiro DC. Synthesis and antioxidant, anti-inflammatory and gastroprotector activities of anethole and related compounds. Bioorg Med Chem 2005; 13:4353-4358.
    • (2005) Bioorg Med Chem , vol.13 , pp. 4353-4358
    • Freire, R.S.1    Morais, S.M.2    Catunda-Junior, F.E.3    Pinheiro, D.C.4
  • 60
    • 30444448245 scopus 로고    scopus 로고
    • Gastroprotective activity of Nigella sativa L oil and its constituent, thymoquinone against acute alcohol-induced gastric mucosal injury in rats
    • Kanter M, Demir H, Karakaya C, Ozbek H. Gastroprotective activity of Nigella sativa L oil and its constituent, thymoquinone against acute alcohol-induced gastric mucosal injury in rats. World J Gastroenterol 2005; 11:6662-6666.
    • (2005) World J Gastroenterol , vol.11 , pp. 6662-6666
    • Kanter, M.1    Demir, H.2    Karakaya, C.3    Ozbek, H.4
  • 61
    • 20144374311 scopus 로고    scopus 로고
    • Burn-induced oxidative injury of the gut is ameliorated by the leukotriene receptor blocker montelukast
    • Kabasakal L, Sener G, Cetinel S, et al. Burn-induced oxidative injury of the gut is ameliorated by the leukotriene receptor blocker montelukast. Prostaglandins Leukot Essent Fatty Acids 2005; 72:431-440.
    • (2005) Prostaglandins Leukot Essent Fatty Acids , vol.72 , pp. 431-440
    • Kabasakal, L.1    Sener, G.2    Cetinel, S.3
  • 62
    • 24144473427 scopus 로고    scopus 로고
    • Lansoprazole prevents experimental gastric injury induced by nonsteroidal anti-inflammatory drugs through a reduction of mucosal oxidative damage
    • 2 levels or indomethacin-induced cyclooxygenase-2 expression.
    • (2005) World J Gastroenterol , vol.11 , pp. 4052-4060
    • Blandizzi, C.1    Fornai, M.2    Colucci, R.3
  • 63
    • 27444448053 scopus 로고    scopus 로고
    • Long term follow up of patients treated for Helicobacter pylori infection
    • Mera R, Fontham ET, Bravo LE, et al. Long term follow up of patients treated for Helicobacter pylori infection. Gut 2005; 54:1536-1540.
    • (2005) Gut , vol.54 , pp. 1536-1540
    • Mera, R.1    Fontham, E.T.2    Bravo, L.E.3
  • 64
    • 0031897632 scopus 로고    scopus 로고
    • NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Ghosh S, May MJ, Kopp EB. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998; 16:225-260.
    • (1998) Annu Rev Immunol , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 65
    • 27144537849 scopus 로고    scopus 로고
    • Low pH and Helicobacter pylori increase nuclear factor kappa B binding in gastric epithelial cells: A common pathway for epithelial cell injury?
    • O'Toole D, Abdel-Latif MM, Long A, et al. Low pH and Helicobacter pylori increase nuclear factor kappa B binding in gastric epithelial cells: a common pathway for epithelial cell injury? J Cell Biochem 2005; 96:589-598. NF-κB activity is upregulated in the presence of both H. pylori and low pH, suggesting a common pathway for mucosal injury.
    • (2005) J Cell Biochem , vol.96 , pp. 589-598
    • O'Toole, D.1    Abdel-Latif, M.M.2    Long, A.3
  • 66
    • 18844461709 scopus 로고    scopus 로고
    • Synergism of Helicobacter pylori infection and stress on the augmentation of gastric mucosal damage and its prevention with alpha-tocopherol
    • Oh TY, Yeo M, Han SU, et al. Synergism of Helicobacter pylori infection and stress on the augmentation of gastric mucosal damage and its prevention with alpha-tocopherol. Free Radic Biol Med 2005; 38:1447-1457.
    • (2005) Free Radic Biol Med , vol.38 , pp. 1447-1457
    • Oh, T.Y.1    Yeo, M.2    Han, S.U.3


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