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Volumn 50, Issue SUPPL. 1, 2005, Pages

Rebamipide decreases the susceptibility of gastric mucosa to acid-induced injury in rats by inhibiting neutrophil activation

Author keywords

Activated neutrophils; Gastric acid; Gastric microvascular permeability; Gastric mucosal permeability; Rebamipide

Indexed keywords

ANTIULCER AGENT; EDETATE CHROMIUM CR 51; EGLIN C; EVANS BLUE; LEUKOCYTE ELASTASE INHIBITOR; MONOCLONAL ANTIBODY; PADGEM PROTEIN; REBAMIPIDE; SIVELESTAT;

EID: 25644448093     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-005-2807-2     Document Type: Article
Times cited : (10)

References (28)
  • 1
    • 0022035645 scopus 로고
    • Leukocyte-endothelial interactions
    • Harlan JM: Leukocyte-endothelial interactions. Blood 65:513-525, 1985
    • (1985) Blood , vol.65 , pp. 513-525
    • Harlan, J.M.1
  • 2
    • 0001574772 scopus 로고
    • Phagocytic cells. Oxygen-independent antimicrobial systems
    • JI Gallin, IM Goldstein, R Synderman (eds). New York, Raven Press
    • Elsbach P, Weiss J: Phagocytic cells. Oxygen-independent antimicrobial systems. In Inflammation: basic Principles and Clinical Correlates. JI Gallin, IM Goldstein, R Synderman (eds). New York, Raven Press, 1988, pp 445-470
    • (1988) Inflammation: Basic Principles and Clinical Correlates , pp. 445-470
    • Elsbach, P.1    Weiss, J.2
  • 3
    • 0029895919 scopus 로고    scopus 로고
    • Role of granulocyte elastase in the formation of hemorrhagic shock-induced gastric mucosal lesions in the rat
    • Kushimoto S, Okajima K, Uchiba M, Murakami K, Harada N, Okabe H, Takatsuki K: Role of granulocyte elastase in the formation of hemorrhagic shock-induced gastric mucosal lesions in the rat. Crit Care Med 24:1041-1046, 1996
    • (1996) Crit Care Med , vol.24 , pp. 1041-1046
    • Kushimoto, S.1    Okajima, K.2    Uchiba, M.3    Murakami, K.4    Harada, N.5    Okabe, H.6    Takatsuki, K.7
  • 4
    • 0032212074 scopus 로고    scopus 로고
    • Role of neutrophil elastase in stress-induced gastric mucosal injury in rats
    • Liu W, Okajima K, Murakami K, Harada N, Isobe H, Irie T: Role of neutrophil elastase in stress-induced gastric mucosal injury in rats. J Lab Clin Med 132:432-439, 1998
    • (1998) J Lab Clin Med , vol.132 , pp. 432-439
    • Liu, W.1    Okajima, K.2    Murakami, K.3    Harada, N.4    Isobe, H.5    Irie, T.6
  • 5
  • 6
    • 0024999177 scopus 로고
    • Reperfusion-induced leukocyte infiltration: Role of elastase
    • Zimmerman BJ, Granger DN: Reperfusion-induced leukocyte infiltration: role of elastase. Am J Physiol 259:H390-H394, 1990
    • (1990) Am J Physiol , vol.259
    • Zimmerman, B.J.1    Granger, D.N.2
  • 7
    • 0021941090 scopus 로고
    • Elastase in tissue injury
    • Janoff A: Elastase in tissue injury. Ann Rev Med 36:207-216, 1985
    • (1985) Ann Rev Med , vol.36 , pp. 207-216
    • Janoff, A.1
  • 8
    • 0023686453 scopus 로고    scopus 로고
    • Gastric mucosal blood flow and mucosal protection
    • Holm L: Gastric mucosal blood flow and mucosal protection. J Clin Gastroenterol 10(Suppl):S114-S119, 1998
    • (1998) J Clin Gastroenterol , vol.10 , Issue.SUPPL.
    • Holm, L.1
  • 9
    • 0033848012 scopus 로고    scopus 로고
    • Inhibition of neutrophil activation by ranitidine contributes to prevent stress-induced gastric mucosal injury in rats
    • Okajima K, Murakami K, Liu W, Uchiba M: Inhibition of neutrophil activation by ranitidine contributes to prevent stress-induced gastric mucosal injury in rats. Crit Care Med 28:2858-2865, 2000
    • (2000) Crit Care Med , vol.28 , pp. 2858-2865
    • Okajima, K.1    Murakami, K.2    Liu, W.3    Uchiba, M.4
  • 10
    • 0022859631 scopus 로고
    • Studies on 2(1H)-quinolinone derivatives as gastric antiulcer active agents. Synthesis and antiulcer activity of the metabolites of 2-(4-chlorobenzoyamino)-3-[2(1H)-quinolinon-4-yl] propionic acid
    • Uchida M, Tabusa F, Komatsu M, Morita S, Kanbe T, Nakagawa K: Studies on 2(1H)-quinolinone derivatives as gastric antiulcer active agents. Synthesis and antiulcer activity of the metabolites of 2-(4-chlorobenzoyamino)-3-[2(1H)- quinolinon-4-yl] propionic acid. Chem Pharm Bull 34:4821-4824, 1986
    • (1986) Chem Pharm Bull , vol.34 , pp. 4821-4824
    • Uchida, M.1    Tabusa, F.2    Komatsu, M.3    Morita, S.4    Kanbe, T.5    Nakagawa, K.6
  • 11
    • 0023629705 scopus 로고
    • Gastric mucosal protection by OPC-12759, a novel antiulcer compound, in the rat
    • Yamasaki K, Kanbe T, Chijiwa T, Ishiyama H, Morita S: Gastric mucosal protection by OPC-12759, a novel antiulcer compound, in the rat. Eur J Pharmacol 142:23-29, 1987
    • (1987) Eur J Pharmacol , vol.142 , pp. 23-29
    • Yamasaki, K.1    Kanbe, T.2    Chijiwa, T.3    Ishiyama, H.4    Morita, S.5
  • 12
    • 0026557227 scopus 로고
    • Antiulcer mechanism of action of rebamipide, a novel antiulcer compound, on diethyldithiocarbamate-induced antral gastric ulcers in rats
    • Ogino K, Hobara T, Ishiyama H, Yamasaki K, Kobayashi H, Izumi Y, Oka S: Antiulcer mechanism of action of rebamipide, a novel antiulcer compound, on diethyldithiocarbamate-induced antral gastric ulcers in rats. Eur J Pharmacol 212:9-13, 1992
    • (1992) Eur J Pharmacol , vol.212 , pp. 9-13
    • Ogino, K.1    Hobara, T.2    Ishiyama, H.3    Yamasaki, K.4    Kobayashi, H.5    Izumi, Y.6    Oka, S.7
  • 13
    • 0027217058 scopus 로고
    • Stimulation of prostaglandin biosythesis mediates gastroprotective effect of rebamipide in rats
    • Kleine A, Kluge S, Peskar BM: Stimulation of prostaglandin biosythesis mediates gastroprotective effect of rebamipide in rats. Dig Dis Sci 38:1441-1449, 1993
    • (1993) Dig Dis Sci , vol.38 , pp. 1441-1449
    • Kleine, A.1    Kluge, S.2    Peskar, B.M.3
  • 14
    • 0028572568 scopus 로고
    • Role of lipid peroxidation in protection of rats by rebamipide against gastric mucosal lesions induced by stress plus indomethacin
    • Yamasaki K, Sakurai K: Role of lipid peroxidation in protection of rats by rebamipide against gastric mucosal lesions induced by stress plus indomethacin. Pathophysiology 1:251-257, 1994
    • (1994) Pathophysiology , vol.1 , pp. 251-257
    • Yamasaki, K.1    Sakurai, K.2
  • 15
    • 0032160419 scopus 로고    scopus 로고
    • Rebamipide: Overview of its mechanisms of action and efficacy in mucosal protection and ulcer healing
    • Arakawa T, Kobayashi K, Yoshikawa T, Tanawski A: Rebamipide: Overview of its mechanisms of action and efficacy in mucosal protection and ulcer healing. Dig Dis Sci 43(Suppl 9):5S-13S, 1998
    • (1998) Dig Dis Sci , vol.43 , Issue.9 SUPPL.
    • Arakawa, T.1    Kobayashi, K.2    Yoshikawa, T.3    Tanawski, A.4
  • 16
    • 0031051544 scopus 로고    scopus 로고
    • Rebamipide attenuates indomethacin-induced gastric mucosal lesion formation by inhibiting activation of leukocyte in rats
    • Murakami K, Okajima K, Harada N, Isobe H, Okabe H: Rebamipide attenuates indomethacin-induced gastric mucosal lesion formation by inhibiting activation of leukocyte in rats. Dig Dis Sci 42:319-325, 1997
    • (1997) Dig Dis Sci , vol.42 , pp. 319-325
    • Murakami, K.1    Okajima, K.2    Harada, N.3    Isobe, H.4    Okabe, H.5
  • 18
    • 0024999177 scopus 로고
    • Reperfusion-induced leukocyte infiltration: Role of elastase
    • Zimmerman BJ, Granger DN: Reperfusion-induced leukocyte infiltration: role of elastase. Am J Physiol 259:H390-H394, 1990
    • (1990) Am J Physiol , vol.259
    • Zimmerman, B.J.1    Granger, D.N.2
  • 19
    • 0014260417 scopus 로고
    • The effect of drugs on the production and recovery processes of the stress ulcer
    • Takagi K, Okabe S: The effect of drugs on the production and recovery processes of the stress ulcer. Jpn J Pharmacol 18:9-18, 1968
    • (1968) Jpn J Pharmacol , vol.18 , pp. 9-18
    • Takagi, K.1    Okabe, S.2
  • 20
    • 0028199216 scopus 로고
    • Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: Role of tumor necrosis factor alpha
    • Santucci L, Fiorucci S, Giansanti M, Brunori PM, Di Matteo FM, Morelli A: Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: role of tumor necrosis factor alpha. Gut 35:909-915, 1994
    • (1994) Gut , vol.35 , pp. 909-915
    • Santucci, L.1    Fiorucci, S.2    Giansanti, M.3    Brunori, P.M.4    Di Matteo, F.M.5    Morelli, A.6
  • 21
    • 0027411517 scopus 로고
    • Mucosal injury and inflammation in a model of chronic granulomatous colitis in rats
    • Yamada T, Sartor RB, Marshall S, Specian RD, Grisham MB: Mucosal injury and inflammation in a model of chronic granulomatous colitis in rats. Gastroenterology 104:759-771, 1993
    • (1993) Gastroenterology , vol.104 , pp. 759-771
    • Yamada, T.1    Sartor, R.B.2    Marshall, S.3    Specian, R.D.4    Grisham, M.B.5
  • 22
    • 0034120023 scopus 로고    scopus 로고
    • Activated neutrophils impair gastric cytoprotection role of neutrophil elastase
    • Harada N, Okajima K, Liu W, Uchiba M: Activated neutrophils impair gastric cytoprotection role of neutrophil elastase. Dig Dis Sci 45:1210-1216, 2000
    • (2000) Dig Dis Sci , vol.45 , pp. 1210-1216
    • Harada, N.1    Okajima, K.2    Liu, W.3    Uchiba, M.4
  • 23
    • 0141779502 scopus 로고
    • The role of blood flow in gastric mucosal defence, damage and healing
    • Sorbye H, Svanes K: The role of blood flow in gastric mucosal defence, damage and healing. Dig Dis Sci 12:305-317, 1994
    • (1994) Dig Dis Sci , vol.12 , pp. 305-317
    • Sorbye, H.1    Svanes, K.2
  • 24
    • 0002359652 scopus 로고
    • Elastase and cathepsin G: The serine protease of human neutrophil leukocytes and spleen
    • AJ Barret (eds). Amsterdam, Elsevier/North-Holland Biomedical Press
    • Starkey PM: Elastase and cathepsin G: the serine protease of human neutrophil leukocytes and spleen. In Proteinases in Mammalian Cells and Tissues. AJ Barret (eds). Amsterdam, Elsevier/North-Holland Biomedical Press, 1977, pp 57-89
    • (1977) Proteinases in Mammalian Cells and Tissues , pp. 57-89
    • Starkey, P.M.1
  • 26
    • 0026004729 scopus 로고
    • Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils
    • Lorant DE, Patel KD, McIntyre TM, McEver RP, Prescott SM, Zimmerman GA: Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils. J Cell Biol 115:223-234, 1991
    • (1991) J Cell Biol , vol.115 , pp. 223-234
    • Lorant, D.E.1    Patel, K.D.2    McIntyre, T.M.3    McEver, R.P.4    Prescott, S.M.5    Zimmerman, G.A.6
  • 27
    • 0024364675 scopus 로고
    • GMP-140, a platelet a-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies
    • McEver RP, Beckstead JH, Moore KL, Marshall-Carlson L, Bainton DF: GMP-140, a platelet a-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies. J Clin Invest 84:92-99, 1989
    • (1989) J Clin Invest , vol.84 , pp. 92-99
    • McEver, R.P.1    Beckstead, J.H.2    Moore, K.L.3    Marshall-Carlson, L.4    Bainton, D.F.5
  • 28
    • 0026059929 scopus 로고
    • Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils
    • Patel KD, Zimmerman GA, Prescott SM, McEver RP, McIntyre TM: Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils. J Cell Biol 112:749-759, 1991
    • (1991) J Cell Biol , vol.112 , pp. 749-759
    • Patel, K.D.1    Zimmerman, G.A.2    Prescott, S.M.3    McEver, R.P.4    McIntyre, T.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.