Modulation of lipoprotein metabolism by inhibition of sphingomyelin synthesis in ApoE knockout mice

Atherosclerosis

Volumn 189, Issue 2, 2006, Pages 264-272

  Park, Tae Sik ^a   Panek, Robert L ^a   Rekhter, Mark D ^a   Mueller, Sandra Bak ^a   Rosebury, Wendy S ^a   Robertson, Andrew ^a   Hanselman, Jeffrey C ^a   Kindt, Erick ^a   Homan, Reynold ^a   Karathanasis, Sotirios K ^a  

^a PFIZER INC   (United States)

Author keywords

Atherosclerosis; Cholesterol; Lipoprotein; Serine palmitoyltransferase; Sphingolipid; SREBP

Indexed keywords

ANTILIPEMIC AGENT; APOLIPOPROTEIN A1; APOLIPOPROTEIN E; CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; ENZYME INHIBITOR; FATTY ACID SYNTHASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PHOSPHATIDYLCHOLINE; PROTEIN; RNA; SERINE PALMITOYLTRANSFERASE; SPHINGOMYELIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; THERMOZYMOCIDIN; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; DRUG TARGETING; DYSLIPIDEMIA; ENZYME INDUCTION; ENZYME REPRESSION; FEMORAL ARTERY; KNOCKOUT MOUSE; LIPOPROTEIN METABOLISM; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BLOTTING, WESTERN; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CHOLESTEROL, VLDL; DISEASE MODELS, ANIMAL; FATTY ACIDS, MONOUNSATURATED; GENE EXPRESSION REGULATION; IMMUNOSUPPRESSIVE AGENTS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; RNA; SPHINGOMYELINS; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 33750359322     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2005.12.029     Document Type: Article

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