Increased expression of serine palmitoyltransferase (SPT) in balloon-injured rat carotid artery

Thrombosis and Haemostasis

Volumn 86, Issue 5, 2001, Pages 1320-1326

  Uhlinger, D J ^a   Carton, J M ^a   Argentieri, D C ^a   Damiano, B P ^a   D'Andrea, M R ^a  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

Immunohistochemistry; Rat balloon angioplasty; Reactive fibroblasts; Restenosis; Serine palmitoyltransferase 1 and 2

Indexed keywords

SERINE PALMITOYLTRANSFERASE; SPHINGOLIPID; ACYLTRANSFERASE;

ADVENTITIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL INJURY; CAROTID ARTERY INJURY; CATALYSIS; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; FIBROBLAST; INFLAMMATION; INTIMA; LIPOGENESIS; MALE; NONHUMAN; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE; WOUND HEALING; ANIMAL; CYTOLOGY; ENZYMOLOGY; IMMUNOHISTOCHEMISTRY; METABOLISM; RAT STRAIN;

ACYLTRANSFERASES; ANGIOPLASTY, BALLOON; ANIMAL; CAROTID ARTERY INJURIES; FIBROBLASTS; IMMUNOHISTOCHEMISTRY; MALE; MODELS, ANIMAL; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0035171133     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1616067     Document Type: Article

References (34)

1. Functions of sphingolipids and sphingolipid breakdown products in cellular regulation
2. Introduction: Sphingolipids and their metabolites in cell regulation
3. Signal transduction through the sphingomyelin pathway
4. Enzymology of long-chain base synthesis by liver: Characterization of serine palmitoyltransferase in rat liver microsomes
5. Signal transduction through lipid second messengers
6. The sphingomyelin cycle and the second messenger function of ceramide
7. Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
8. The role of ceramide in cell signaling
9. Sphingolipid metabolism and cell growth regulation
10. Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5
11. Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1
12. Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6
13. Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis
14. The vessel wall reaction in restenosis
15. Mechanisms of stenosis after arterial injury
16. Adventitial remodeling after coronary arterial injury
17. Adventitial fibroblasts. Defining a role in vessel wall remodeling
18. Current concepts in restenosis following balloon angioplasty
19. The current status of stentin - Pathobiology
20. The intima - Soil for atherosclerosis and restenosis
21. Restenosis following angioplasty in the swine coronary artery is inhibited by an orally active PDGF-receptor tyrosine kinase inhibitor, RPR101511A
22. Inhibition of platelet-derived growth factor receptor tyrosine kinase inhibits vascular smooth muscle cell migration and proliferation
23. Antisense oligonucleotide inhibition of PDGFR-beta receptor subunit expression directs suppression of intimal thickening
24. Factors controlling the development of arterial lesions after injury
25. Substantial inhibition of neo-intimal response to balloon injury in the rat carotid artery using a combination of antibodies to platelet-derived growth factor-BB and basic fibroblast growth factor
26. In vivo effect of TGF-beta 1 - Enhanced intimal thickening by administration of TGF-beta 1 in rabbit arteries injured with a balloon catheter
27. Mechanism of inhibition of neointimal formation by the angiotensin-converting enzyme inhibitor cilazapril - A study in balloon catheter-injured rat carotid arteries
28. Activation of the de novo biosynthesis of sphingolipids mediates angiotensin II type 2 receptor-induced apoptosis
29. Increased expression of protease activated receptor-2 (PAR-2) in balloon-injured rat carotid artery
30. Expression of protease-activated receptors-1 and -2 in the tumor microenvironment of human carcinomas
31. Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
32. Flavopiridol inhibits smooth muscle cell proliferation in vitro and neointimal formation in vivo after carotid injury in the rat
33. Regulation of vascular smooth muscle cell migration and proliferation in vitro and in injured rat arteries by a synthetic matrix metalloproteinase inhibitor