메뉴 건너뛰기




Volumn 54, Issue 5, 2006, Pages 323-333

Mechanisms of tumor escape: Role of tumor microenvironment in inducing apoptosis of cytolytic effector cells

Author keywords

Apoptosis; Natural cytotoxicity receptor; NKG2D; Soluble HLA I; Stromal cells; Tumor escape

Indexed keywords

CD8 ANTIGEN; CYCLOSPORIN A; GAMMA INTERFERON; HLA ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN; NATURAL KILLER CELL RECEPTOR NKG2D; TRANSFORMING GROWTH FACTOR BETA;

EID: 33750290402     PISSN: 0004069X     EISSN: 16614917     Source Type: Journal    
DOI: 10.1007/s00005-006-0038-7     Document Type: Review
Times cited : (59)

References (113)
  • 1
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal S. and Pittenger M. F. (2005): Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood, 105, 1815-1822.
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 2
    • 0027312306 scopus 로고
    • Interferon-gamma reduces tumor-induced macrophage-mediated suppression: Role of prostaglandin-E2 and tumour necrosis factor-alpha
    • Alleva D. G., Burger C. J. and Elgert K. D. (1993): Interferon-gamma reduces tumor-induced macrophage-mediated suppression: role of prostaglandin-E2 and tumour necrosis factor-alpha. Immunopharmacology, 25, 215-227.
    • (1993) Immunopharmacology , vol.25 , pp. 215-227
    • Alleva, D.G.1    Burger, C.J.2    Elgert, K.D.3
  • 3
    • 18844404360 scopus 로고    scopus 로고
    • Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed cell death 1 pathway
    • Augello A., Tasso R., Negrini S. M., Amatesi A., Indiveri F., Cancedda R. and Pennesi G. (2005): Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed cell death 1 pathway. Eur. J. Immunol., 35, 1482-1490.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 1482-1490
    • Augello, A.1    Tasso, R.2    Negrini, S.M.3    Amatesi, A.4    Indiveri, F.5    Cancedda, R.6    Pennesi, G.7
  • 4
    • 0036302172 scopus 로고    scopus 로고
    • Programmed contraction of CD8+ T cells after infection
    • Badovinac V. P., Porter B. B. and Harty J. T. (2002): Programmed contraction of CD8+ T cells after infection. Nat. Immunol., 3, 619-626.
    • (2002) Nat. Immunol. , vol.3 , pp. 619-626
    • Badovinac, V.P.1    Porter, B.B.2    Harty, J.T.3
  • 5
    • 0032101973 scopus 로고    scopus 로고
    • Killer cell inhibitory receptors for MHC class I molecules regulate lysis of melanoma cells mediated by NK cells, gamma delta T cells, and antigen-specific CTL
    • Bakker A. B., Phillips J. H., Figdor C. G. and Lanier L. L (1998): Killer cell inhibitory receptors for MHC class I molecules regulate lysis of melanoma cells mediated by NK cells, gamma delta T cells, and antigen-specific CTL. J. Immunol., 160, 5239-5245.
    • (1998) J. Immunol. , vol.160 , pp. 5239-5245
    • Bakker, A.B.1    Phillips, J.H.2    Figdor, C.G.3    Lanier, L.L.4
  • 6
    • 0033618504 scopus 로고    scopus 로고
    • Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MIC-A
    • Bauer S., Groh V., Wu J., Steinle A., Phillips J. H., Lanier L. L. and Spies T. (1999): Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MIC-A. Science, 285, 727-729.
    • (1999) Science , vol.285 , pp. 727-729
    • Bauer, S.1    Groh, V.2    Wu, J.3    Steinle, A.4    Phillips, J.H.5    Lanier, L.L.6    Spies, T.7
  • 7
    • 0034669980 scopus 로고    scopus 로고
    • IFN-gamma can promote tumor evasion of the immune system in vivo by down-regulating cellular levels of an endogenous tumor antigen
    • Beatty G. L. and Paterson Y. (2000): IFN-gamma can promote tumor evasion of the immune system in vivo by down-regulating cellular levels of an endogenous tumor antigen. J. Immunol., 165, 5502-5508.
    • (2000) J. Immunol. , vol.165 , pp. 5502-5508
    • Beatty, G.L.1    Paterson, Y.2
  • 9
    • 0032103027 scopus 로고    scopus 로고
    • The Fs counterattack in vivo: Apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoima
    • Bennett M. W., O'Connell J., O'Sullivan G. C., Brady C., Roche D., Collins J. K. and Shanahan F. (1998): The Fs counterattack in vivo: apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoima. J. Immunol., 160, 5669-5675.
    • (1998) J. Immunol. , vol.160 , pp. 5669-5675
    • Bennett, M.W.1    O'Connell, J.2    O'Sullivan, G.C.3    Brady, C.4    Roche, D.5    Collins, J.K.6    Shanahan, F.7
  • 10
    • 14944339174 scopus 로고    scopus 로고
    • Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T cell unresponsiveness
    • Beyth S., Borovsky Z., Mevorach D., Liebergall M., Gazit Z., Aslan H., Galum E. and Rachmilewitz J. (2005): Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T cell unresponsiveness. Blood, 105, 2214-2219.
    • (2005) Blood , vol.105 , pp. 2214-2219
    • Beyth, S.1    Borovsky, Z.2    Mevorach, D.3    Liebergall, M.4    Gazit, Z.5    Aslan, H.6    Galum, E.7    Rachmilewitz, J.8
  • 11
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • Bogdan C. (2001): Nitric oxide and the immune response. Nat. Immunol., 2, 907-916.
    • (2001) Nat. Immunol. , vol.2 , pp. 907-916
    • Bogdan, C.1
  • 12
    • 0030008642 scopus 로고    scopus 로고
    • Extracellular pH controls pre-mRNA alternative splicing of tenascin-C in normal, but not in malignantly transformed cells
    • Borsi L., Alemanni G., Gaggero B. and Zardi L. (1996): Extracellular pH controls pre-mRNA alternative splicing of tenascin-C in normal, but not in malignantly transformed cells. Int. J. Cancer, 29, 632-635.
    • (1996) Int. J. Cancer , vol.29 , pp. 632-635
    • Borsi, L.1    Alemanni, G.2    Gaggero, B.3    Zardi, L.4
  • 13
    • 0032974475 scopus 로고    scopus 로고
    • Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells
    • Bossi G. and Griffths G. M. (1999): Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells. Nat. Med., 5, 90-96.
    • (1999) Nat. Med. , vol.5 , pp. 90-96
    • Bossi, G.1    Griffths, G.M.2
  • 14
    • 23444456772 scopus 로고    scopus 로고
    • Regulation of immune responses by 1-arginine metabolism
    • Bronte V. and Zanovello P. (2005): Regulation of immune responses by 1-arginine metabolism. Nat. Rev. Immunol., 5, 641-654.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 641-654
    • Bronte, V.1    Zanovello, P.2
  • 16
    • 0034551670 scopus 로고    scopus 로고
    • Identification of a CD11b+/Gr-1+/CD31+ myeloid progenitor capable of activating or suppressing CD8+ T cells
    • Bronte V., Apolloni E., Cabrelle A., Ronca R., Serafini P., Zamboni P., Restifo N. P. and Zanovello P. (2000): Identification of a CD11b+/Gr-1+/CD31+ myeloid progenitor capable of activating or suppressing CD8+ T cells. Blood, 96, 3838-3846.
    • (2000) Blood , vol.96 , pp. 3838-3846
    • Bronte, V.1    Apolloni, E.2    Cabrelle, A.3    Ronca, R.4    Serafini, P.5    Zamboni, P.6    Restifo, N.P.7    Zanovello, P.8
  • 18
    • 0035113742 scopus 로고    scopus 로고
    • Macrophage arginase promotes tumor cell growth and suppress nitric oxide mediated cytotoxicity
    • Chang C. I., Liao J. C. and Kuo L. (2001): Macrophage arginase promotes tumor cell growth and suppress nitric oxide mediated cytotoxicity. Cancer Res., 61, 110-1106.
    • (2001) Cancer Res. , vol.61 , pp. 110-1106
    • Chang, C.I.1    Liao, J.C.2    Kuo, L.3
  • 19
    • 0028600060 scopus 로고
    • Expression and regulation of adhesion molecules by gammadelta T cells from tissues and intestinal epithelium
    • Chao C. C., Sandor M. and Dailey M. O. (1994): Expression and regulation of adhesion molecules by gammadelta T cells from tissues and intestinal epithelium. Eur. J. Immunol., 24, 3180-3187.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 3180-3187
    • Chao, C.C.1    Sandor, M.2    Dailey, M.O.3
  • 21
    • 0029937941 scopus 로고    scopus 로고
    • Inflammatory cells infiltrating human colorectal carcinomas express HLA class II but not B7-1 and B7-2 costimulatory molecules of T cell activation
    • Chaux P., Moutet M., Faivre J., Martin F. and Martin M. (1996): Inflammatory cells infiltrating human colorectal carcinomas express HLA class II but not B7-1 and B7-2 costimulatory molecules of T cell activation. Lab. Invest., 74, 975-983.
    • (1996) Lab. Invest. , vol.74 , pp. 975-983
    • Chaux, P.1    Moutet, M.2    Faivre, J.3    Martin, F.4    Martin, M.5
  • 23
    • 0035822618 scopus 로고    scopus 로고
    • Classical and slow-binding inhibitors of human type II arginase
    • Colleuori D. M. and Ash D. E. (2001): Classical and slow-binding inhibitors of human type II arginase. Biochemistry, 40, 9356-9362.
    • (2001) Biochemistry , vol.40 , pp. 9356-9362
    • Colleuori, D.M.1    Ash, D.E.2
  • 25
    • 0035099068 scopus 로고    scopus 로고
    • ULBPs, novel MHC class-I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor
    • Cosman D., Mullberg J., Sutherland C. L., Chin W., Armitage R., Fanslow W., Kubin M. and Chalupny N. J. (2001): ULBPs, novel MHC class-I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity, 14, 123-133.
    • (2001) Immunity , vol.14 , pp. 123-133
    • Cosman, D.1    Mullberg, J.2    Sutherland, C.L.3    Chin, W.4    Armitage, R.5    Fanslow, W.6    Kubin, M.7    Chalupny, N.J.8
  • 28
    • 0026094306 scopus 로고
    • Interleukin-10 (IL-10) inhibits cytokine synthesis by human monocytes-an autoregulatory role of IL-10 produced by monocytes
    • De Waal Malefyt R., Abrams J., Bennett B., Figdor C. G. and de Vries J. E. (1991): Interleukin-10 (IL-10) inhibits cytokine synthesis by human monocytes-an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med., 174, 1209-1220.
    • (1991) J. Exp. Med. , vol.174 , pp. 1209-1220
    • De Waal Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    De Vries, J.E.5
  • 29
    • 0032984496 scopus 로고    scopus 로고
    • CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T lymphocyte tolerance and augments anti-tumour vaccine efficacy
    • Diehl L., den Boer A. T., Schoenberger S. P., van der Voort E. I., Schumaker T. N., Melief C. J., Offringa R. and Toes R. E. (1999): CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T lymphocyte tolerance and augments anti-tumour vaccine efficacy. Nat. Med., 5, 774-779.
    • (1999) Nat. Med. , vol.5 , pp. 774-779
    • Diehl, L.1    Den Boer, A.T.2    Schoenberger, S.P.3    Van Der Voort, E.I.4    Schumaker, T.N.5    Melief, C.J.6    Offringa, R.7    Toes, R.E.8
  • 30
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola M., Carlo-Stella C., Magni M., Milanesi M., Longoni P. D., Matteucci P., Grisanti S. and Gianni A. M. (2002): Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood, 99, 3838-3843.
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3    Milanesi, M.4    Longoni, P.D.5    Matteucci, P.6    Grisanti, S.7    Gianni, A.M.8
  • 31
    • 0242410394 scopus 로고    scopus 로고
    • Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals
    • Djouad F., Plence P., Bony C., Tropel P., Apparailly F., Sany J., Noel D. and Iorgensen C. (2003): Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Blood, 102, 3837-3844.
    • (2003) Blood , vol.102 , pp. 3837-3844
    • Djouad, F.1    Plence, P.2    Bony, C.3    Tropel, P.4    Apparailly, F.5    Sany, J.6    Noel, D.7    Iorgensen, C.8
  • 32
    • 0034956593 scopus 로고    scopus 로고
    • TCR gamma delta cytotoxic T lymphocytes expressing the killer cell-inhibitory receptor p58.2 (CD158b) selectively lyse acute myeloid leukemia cells
    • Dolstra H., Fredrix H., van der Meer A., de Witte T., Figdor C. and van de Weil-van Kemenade E. (2001): TCR gamma delta cytotoxic T lymphocytes expressing the killer cell-inhibitory receptor p58.2 (CD158b) selectively lyse acute myeloid leukemia cells. Bone Marrow Transplant., 27, 1087-1093.
    • (2001) Bone Marrow Transplant. , vol.27 , pp. 1087-1093
    • Dolstra, H.1    Fredrix, H.2    Van Der Meer, A.3    De Witte, T.4    Figdor, C.5    Van De Weil-van Kemenade, E.6
  • 33
  • 35
    • 0035300566 scopus 로고    scopus 로고
    • Inhibition of caspases maintains the antineoplastic function of gammadelta T cells repeatedly challenged with lymphoma cells
    • Ferrarini M., Consogno G., Rovere P., Sciorati C., Dagna L., Resta D., Rugarli C. and Manfredi A. A.(2001): Inhibition of caspases maintains the antineoplastic function of gammadelta T cells repeatedly challenged with lymphoma cells. Cancer Res., 61, 3092-3095.
    • (2001) Cancer Res. , vol.61 , pp. 3092-3095
    • Ferrarini, M.1    Consogno, G.2    Rovere, P.3    Sciorati, C.4    Dagna, L.5    Resta, D.6    Rugarli, C.7    Manfredi, A.A.8
  • 36
    • 0036007415 scopus 로고    scopus 로고
    • Human gammadelta T cells: A nonredundant system in the immune-surveillance against cancer
    • Ferrarini M., Ferrero E., Dagna L., Poggi A. and Zocchi M. R. (2002): Human gammadelta T cells: a nonredundant system in the immune-surveillance against cancer. Trends Immunol., 23, 14-18.
    • (2002) Trends Immunol. , vol.23 , pp. 14-18
    • Ferrarini, M.1    Ferrero, E.2    Dagna, L.3    Poggi, A.4    Zocchi, M.R.5
  • 37
    • 0031926716 scopus 로고    scopus 로고
    • Tumor-driven matrix invasion by infiltrating lymphocytes: Involvement of the α1 integrin I-domain
    • Ferrero E., Fabbri M., Poggi A., Galati G., Bernasconi S. and Zocchi M. R. (1998): Tumor-driven matrix invasion by infiltrating lymphocytes: involvement of the α1 integrin I-domain. Eur. J. Immunol., 28, 2530-2536.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2530-2536
    • Ferrero, E.1    Fabbri, M.2    Poggi, A.3    Galati, G.4    Bernasconi, S.5    Zocchi, M.R.6
  • 39
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • Fontenot J. D., Rasmussen J. P., Gavin M. A. and Rudensky A. Y. (2005): A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat. Immunol., 6, 1142-1151.
    • (2005) Nat. Immunol. , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 40
    • 16844363097 scopus 로고    scopus 로고
    • A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
    • Fontenot J. D. and Rudensky A. Y. (2005): A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat. Immunol., 6, 331-337.
    • (2005) Nat. Immunol. , vol.6 , pp. 331-337
    • Fontenot, J.D.1    Rudensky, A.Y.2
  • 41
    • 0037136328 scopus 로고    scopus 로고
    • Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase
    • Frumento G., Rotondo R., Tonetti M., Damonte G., Benatti U. and Ferrara G. B. (2002): Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase. J. Exp. Med., 196, 459-468.
    • (2002) J. Exp. Med. , vol.196 , pp. 459-468
    • Frumento, G.1    Rotondo, R.2    Tonetti, M.3    Damonte, G.4    Benatti, U.5    Ferrara, G.B.6
  • 43
    • 0038069515 scopus 로고    scopus 로고
    • MHC class I antigen, immune surveillance and tumour immune escape
    • Garcia-Lora A., Algarra I. and Garrido F. (2003): MHC class I antigen, immune surveillance and tumour immune escape. J. Cell Physiol., 195, 346-355.
    • (2003) J. Cell Physiol. , vol.195 , pp. 346-355
    • Garcia-Lora, A.1    Algarra, I.2    Garrido, F.3
  • 45
    • 0033536068 scopus 로고    scopus 로고
    • Broad tumor-associated expression and recognition by tumor-derived gammadelta T cells of MIC-A and MICB
    • Groh V. R., Rhinehart H., Secrist S., Bauer K. Grabstein H. and Spies T. (1999): Broad tumor-associated expression and recognition by tumor-derived gammadelta T cells of MIC-A and MICB. Proc. Natl. Acad. Sci. USA, 96, 6879-6884.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6879-6884
    • Groh, V.R.1    Rhinehart, H.2    Secrist, S.3    Bauer, K.4    Grabstein, H.5    Spies, T.6
  • 46
    • 0032513388 scopus 로고    scopus 로고
    • Recognition of stress-induced MHC molecules by intestinal epithelial gammadeltaT cells
    • Groh V., Steinle A., Bauer S. and Spies T. (1998): Recognition of stress-induced MHC molecules by intestinal epithelial gammadeltaT cells. Science, 279, 1737-1740.
    • (1998) Science , vol.279 , pp. 1737-1740
    • Groh, V.1    Steinle, A.2    Bauer, S.3    Spies, T.4
  • 47
    • 0037126310 scopus 로고    scopus 로고
    • Tumor-derived soluble MIC ligands impair expression of NKG2D and cell activation
    • Groh V., Wu J., Yee C. and Spies T. (2002): Tumor-derived soluble MIC ligands impair expression of NKG2D and cell activation. Nature, 419, 734-738.
    • (2002) Nature , vol.419 , pp. 734-738
    • Groh, V.1    Wu, J.2    Yee, C.3    Spies, T.4
  • 48
    • 0031933948 scopus 로고    scopus 로고
    • Serum levels of soluble intercellular adhesion molecule-1 (ICAM-1, CD54) in patients with non-small-cell lung cancer: Correlation with histological expression of ICAM-1 and tumor stage
    • Grothey A., Heistermann P., Philippou S. and Voigtmann R. (1998): Serum levels of soluble intercellular adhesion molecule-1 (ICAM-1, CD54) in patients with non-small-cell lung cancer: correlation with histological expression of ICAM-1 and tumor stage. Br. J. Cancer, 77, 801-807.
    • (1998) Br. J. Cancer , vol.77 , pp. 801-807
    • Grothey, A.1    Heistermann, P.2    Philippou, S.3    Voigtmann, R.4
  • 50
    • 0037173116 scopus 로고    scopus 로고
    • Isolated allogeneic bone-marrow derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone
    • Horwitz E. M., Gordon P. L., Koo W. K., Marx J. C., Neel M. D., McNall R. Y., Muul L., Hofmann T. (2002): Isolated allogeneic bone-marrow derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: implications for cell therapy of bone. Proc. Natl. Acad. Sci. USA, 99, 8932-8937.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 8932-8937
    • Horwitz, E.M.1    Gordon, P.L.2    Koo, W.K.3    Marx, J.C.4    Neel, M.D.5    McNall, R.Y.6    Muul, L.7    Hofmann, T.8
  • 51
    • 21844444831 scopus 로고    scopus 로고
    • New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
    • Hunter C. A. (2005): New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. Nat. Rev. Immunol., 5, 521-531.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 521-531
    • Hunter, C.A.1
  • 52
    • 0029914331 scopus 로고    scopus 로고
    • Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo
    • Kagi D. Lederman B., Burki K., Zinkernagel R. M. and Hengartner H. (1996): Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu. Rev. Immunol., 14, 207-232.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 207-232
    • Kagi, D.1    Lederman, B.2    Burki, K.3    Zinkernagel, R.M.4    Hengartner, H.5
  • 54
    • 33645088428 scopus 로고    scopus 로고
    • Metastasis: Cell-autonomous mechanisms versus contributions by the tumor microenvironment
    • Kopfstein L. and Christofori G. (2006): Metastasis: cell-autonomous mechanisms versus contributions by the tumor microenvironment. Cell Mol. Life Sci., 63, 449-468.
    • (2006) Cell Mol. Life Sci. , vol.63 , pp. 449-468
    • Kopfstein, L.1    Christofori, G.2
  • 56
    • 0025300414 scopus 로고
    • In search of the "missing self": MHC molecules and NK cell recognition
    • Ljunggren H. G. and Karre K. (1990): In search of the "missing self": MHC molecules and NK cell recognition. Immunol. Today, 11, 237-244.
    • (1990) Immunol. Today , vol.11 , pp. 237-244
    • Ljunggren, H.G.1    Karre, K.2
  • 57
    • 0031944075 scopus 로고    scopus 로고
    • NK cell receptors
    • Lanier L. L. (1998): NK cell receptors. Annu. Rev. Immunol., 16, 359-393.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 359-393
    • Lanier, L.L.1
  • 58
    • 0028881201 scopus 로고
    • Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): Implications for therapeutic use
    • Lazarus H. M., Haynesworth S. E., Gerson S. L., Rosenthal N. S. and Caplan A. I. (1995): Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use. Bone Marrow Transplant., 16, 557-564.
    • (1995) Bone Marrow Transplant. , vol.16 , pp. 557-564
    • Lazarus, H.M.1    Haynesworth, S.E.2    Gerson, S.L.3    Rosenthal, N.S.4    Caplan, A.I.5
  • 59
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K., Rasmusson I., Sundberg B., Gotherstrom C., Hassam M., Uzunel M. and Ringden O. (2004): treatment of severe acute graft-versus host disease with third party haploidentical mesenchymal stem cells. Lancet, 363, 1439-1441.
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3    Gotherstrom, C.4    Hassam, M.5    Uzunel, M.6    Ringden, O.7
  • 61
    • 0032146710 scopus 로고    scopus 로고
    • Involvement of the Fas/Fas ligand pathway in activation-induced cell death of mycobacteria-reactive human gammadelta T cells: A mechanism for the loss of gammadelta T cells in patients with pulmonary tuberculosis
    • Li B., Bessiri H., Rossman M. D., Kramer P., Eyuboglu A. F., Torres M., Sada E., Imir T. and Carding R. S. (1998): Involvement of the Fas/Fas ligand pathway in activation-induced cell death of mycobacteria-reactive human gammadelta T cells: a mechanism for the loss of gammadelta T cells in patients with pulmonary tuberculosis. J. Immunol., 161, 1558-1567.
    • (1998) J. Immunol. , vol.161 , pp. 1558-1567
    • Li, B.1    Bessiri, H.2    Rossman, M.D.3    Kramer, P.4    Eyuboglu, A.F.5    Torres, M.6    Sada, E.7    Imir, T.8    Carding, R.S.9
  • 62
    • 0033007567 scopus 로고    scopus 로고
    • Regulation of immune responses through inhibitory receptors
    • Long E. O. (1999): Regulation of immune responses through inhibitory receptors. Annu. Rev. Immunol., 17, 875-904.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 875-904
    • Long, E.O.1
  • 64
    • 4744358192 scopus 로고    scopus 로고
    • Effective immunotherapy against cancer
    • Malmberg K.-J. (2004): Effective immunotherapy against cancer. Cancer Immunol. Immunother., 53, 879-892.
    • (2004) Cancer Immunol. Immunother. , vol.53 , pp. 879-892
    • Malmberg, K.-J.1
  • 65
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation
    • Meisel R., Zibert A., Laryea M., Gobel U., Daubener W. and Dilloo D. (2004): Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood, 103, 4619-4621.
    • (2004) Blood , vol.103 , pp. 4619-4621
    • Meisel, R.1    Zibert, A.2    Laryea, M.3    Gobel, U.4    Daubener, W.5    Dilloo, D.6
  • 66
    • 5044220930 scopus 로고    scopus 로고
    • IDO expression by dendritic cells: Tolerance and tryptophan catabolism
    • Mellor A. L. and Munn D. H. (2004): IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat. Rev. Immunol., 4, 762-774.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 762-774
    • Mellor, A.L.1    Munn, D.H.2
  • 70
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata S. (1997): Apoptosis by death factor. Cell, 88, 355-365.
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 71
    • 14844331400 scopus 로고    scopus 로고
    • Dendritic-cell-based therapeutic vaccination against cancer
    • Nestle F. O., Farkas A. and Conrad C. (2005): Dendritic-cell-based therapeutic vaccination against cancer. Curr. Opin. Immunol., 17, 163-169.
    • (2005) Curr. Opin. Immunol. , vol.17 , pp. 163-169
    • Nestle, F.O.1    Farkas, A.2    Conrad, C.3
  • 72
    • 0029841427 scopus 로고    scopus 로고
    • Oxidative stress by tumor-derived macrophages suppresses the expression of CD3z chain of T-cell receptor complex and antigen-specific T-cell response
    • Otsuji M., Kimura Y., Aoe T., Okamoto Y. and Saito T. (1996): Oxidative stress by tumor-derived macrophages suppresses the expression of CD3z chain of T-cell receptor complex and antigen-specific T-cell response. Proc. Natl. Acad. Sci. USA, 93, 13119-13124.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13119-13124
    • Otsuji, M.1    Kimura, Y.2    Aoe, T.3    Okamoto, Y.4    Saito, T.5
  • 73
    • 1542357603 scopus 로고    scopus 로고
    • Tumor escape: Antitumor effectors too much of a good thing?
    • Pawelec G. (2004): Tumor escape: antitumor effectors too much of a good thing? Cancer Immunbiol. Immunother., 53, 262-274.
    • (2004) Cancer Immunbiol. Immunother. , vol.53 , pp. 262-274
    • Pawelec, G.1
  • 74
    • 0036829733 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: Analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytoxicity
    • Pende D., Rivera P., Marcenaro S., Chien-Chung C., Biassoni R., Conte R., Kubin M., Cosman D., Ferrone S., Moretta L. and Moretta A. (2002): Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytoxicity. Cancer Res., 62, 6178-6186.
    • (2002) Cancer Res. , vol.62 , pp. 6178-6186
    • Pende, D.1    Rivera, P.2    Marcenaro, S.3    Chien-Chung, C.4    Biassoni, R.5    Conte, R.6    Kubin, M.7    Cosman, D.8    Ferrone, S.9    Moretta, L.10    Moretta, A.11
  • 76
    • 12144291406 scopus 로고    scopus 로고
    • Migration of Vdelta1 and Vdelta2 T cells in response to CXCR3 and CXCR4 ligands in healthy donors and HIV-1-infected patients: Competition by HIV-1 Tat
    • Poggi A., Carosio R., Fenoglio D., Brenci S., Murdaca G., Setti M., Indiveri F., Scabini S., Ferrero E. and Zocchi M. R. (1999): Migration of Vdelta1 and Vdelta2 T cells in response to CXCR3 and CXCR4 ligands in healthy donors and HIV-1-infected patients: competition by HIV-1 Tat. Blood, 103, 2205-2213.
    • (1999) Blood , vol.103 , pp. 2205-2213
    • Poggi, A.1    Carosio, R.2    Fenoglio, D.3    Brenci, S.4    Murdaca, G.5    Setti, M.6    Indiveri, F.7    Scabini, S.8    Ferrero, E.9    Zocchi, M.R.10
  • 77
    • 14044257848 scopus 로고    scopus 로고
    • Tumor-induced apoptosis of human IL2-activated natural killer cells. Role of natural cytotoxicity receptors
    • Poggi A., Massaro A.-M., Negrini S., Contini P. and Zocchi M. R. (2005): Tumor-induced apoptosis of human IL2-activated natural killer cells. Role of natural cytotoxicity receptors. J. Immunol., 174, 2653-2660.
    • (2005) J. Immunol. , vol.174 , pp. 2653-2660
    • Poggi, A.1    Massaro, A.-M.2    Negrini, S.3    Contini, P.4    Zocchi, M.R.5
  • 79
    • 27744541175 scopus 로고    scopus 로고
    • Interaction between human natural killer cells and bone marrow stromal cells induces NK cell triggering. Role of NKp30 and NKG2D receptors
    • Poggi A., Prevosto C., Massaro A.-M., Negrini S., Urbani S., Pierri I., Saccardi R., Gobbi M. and Zocchi M. R. (2005): Interaction between human natural killer cells and bone marrow stromal cells induces NK cell triggering. Role of NKp30 and NKG2D receptors. J. Immunol., 175, 6352-6360.
    • (2005) J. Immunol. , vol.175 , pp. 6352-6360
    • Poggi, A.1    Prevosto, C.2    Massaro, A.-M.3    Negrini, S.4    Urbani, S.5    Pierri, I.6    Saccardi, R.7    Gobbi, M.8    Zocchi, M.R.9
  • 83
    • 0141886188 scopus 로고    scopus 로고
    • Veto-like activity of mesenchymal stem cells: Functional discrimination between cellular responses to alloantigens and recall antigens
    • Potian J. A., Aviv H., Ponzio N. M., Harrison J. S. and Rameshawar P. (2003): Veto-like activity of mesenchymal stem cells: functional discrimination between cellular responses to alloantigens and recall antigens. J. Immunol., 171, 3426-3434.
    • (2003) J. Immunol. , vol.171 , pp. 3426-3434
    • Potian, J.A.1    Aviv, H.2    Ponzio, N.M.3    Harrison, J.S.4    Rameshawar, P.5
  • 85
    • 0033009890 scopus 로고    scopus 로고
    • The central effectors of cell death in the immune system
    • Rathmell J. C. and Thompson C. B. (1999): the central effectors of cell death in the immune system. Annu. Rev. Immunol., 17, 781-828.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 781-828
    • Rathmell, J.C.1    Thompson, C.B.2
  • 86
    • 0037037582 scopus 로고    scopus 로고
    • Interferon-γ is required for the activation-induced death of T lymphocytes
    • Refaeli Y., Parijs L. V., Alexander S. I. and Abbas A. K. (2002): Interferon-γ is required for the activation-induced death of T lymphocytes. J. Exp. Med., 196, 999-1005.
    • (2002) J. Exp. Med. , vol.196 , pp. 999-1005
    • Refaeli, Y.1    Parijs, L.V.2    Alexander, S.I.3    Abbas, A.K.4
  • 88
    • 4644324025 scopus 로고    scopus 로고
    • Cancer immunotherapy: Moving beyond current vaccines
    • Rosenberg S. A., Yang J. C. and Restifo N. P. (2004): Cancer immunotherapy: moving beyond current vaccines. Nat. Med., 10, 909-915.
    • (2004) Nat. Med. , vol.10 , pp. 909-915
    • Rosenberg, S.A.1    Yang, J.C.2    Restifo, N.P.3
  • 89
    • 0035889886 scopus 로고    scopus 로고
    • Tumor-infiltrating macrophages induce apoptosis in activated CD8+ T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide
    • Saio M., Radoja S., Marino M. and Frey A. B. (2001): Tumor-infiltrating macrophages induce apoptosis in activated CD8+ T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide. J. Immunol., 167, 5583-5593.
    • (2001) J. Immunol. , vol.167 , pp. 5583-5593
    • Saio, M.1    Radoja, S.2    Marino, M.3    Frey, A.B.4
  • 90
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S. (2004): Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol., 22, 531-562.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 91
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S. (2005): Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat. Immunol., 6, 345-352.
    • (2005) Nat. Immunol. , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 92
    • 0041737499 scopus 로고    scopus 로고
    • Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia
    • Salih H. R., Antropius H., Gieseke F., Lutz S. Z., Kanz L., Rammensee H. G. and Steinle A. (2003): Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia. Blood, 102, 1389-1396.
    • (2003) Blood , vol.102 , pp. 1389-1396
    • Salih, H.R.1    Antropius, H.2    Gieseke, F.3    Lutz, S.Z.4    Kanz, L.5    Rammensee, H.G.6    Steinle, A.7
  • 93
    • 0037108517 scopus 로고    scopus 로고
    • Cutting edge: Down-regulation of MIC-A on human tumors by proteolytic shedding
    • Salih H. R., Rammensee H. G. and Steinle A. (2002): Cutting edge: down-regulation of MIC-A on human tumors by proteolytic shedding. J. Immunol., 169, 4098-5102.
    • (2002) J. Immunol. , vol.169 , pp. 4098-5102
    • Salih, H.R.1    Rammensee, H.G.2    Steinle, A.3
  • 94
    • 0035874990 scopus 로고    scopus 로고
    • Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppressor of T-cell function in advanced cancer patients
    • Schimielau J. and Finn O. J. (2001): Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppressor of T-cell function in advanced cancer patients. Cancer Res., 61, 4756-4760.
    • (2001) Cancer Res. , vol.61 , pp. 4756-4760
    • Schimielau, J.1    Finn, O.J.2
  • 95
    • 0036456669 scopus 로고    scopus 로고
    • Expansion of human adult stem cells from bone marrow stroma: Conditions that maximize the yields of early progenitors and evaluate their quality
    • Sekiya I., Larson B. L., Smith J. R., Pochampally R., Cui J. G. and Prockop D. J. (2002): Expansion of human adult stem cells from bone marrow stroma: conditions that maximize the yields of early progenitors and evaluate their quality. Stem Cells, 20, 530-541.
    • (2002) Stem Cells , vol.20 , pp. 530-541
    • Sekiya, I.1    Larson, B.L.2    Smith, J.R.3    Pochampally, R.4    Cui, J.G.5    Prockop, D.J.6
  • 96
    • 0036597371 scopus 로고    scopus 로고
    • + suppressor T cells: More questions than answers
    • + suppressor T cells: more questions than answers. Nat. Rev. Immunol., 2, 389-400.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 97
    • 0034449919 scopus 로고    scopus 로고
    • Adhesion molecule cascades direct lymphocyte recirculation and migration during inflammation
    • Steeber D. A. and Tedder T. F. (2001): Adhesion molecule cascades direct lymphocyte recirculation and migration during inflammation. Immunol. Res., 22, 299-317.
    • (2001) Immunol. Res. , vol.22 , pp. 299-317
    • Steeber, D.A.1    Tedder, T.F.2
  • 98
    • 0033647242 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase: A key biochemical signal for cell migration in response to chemokines
    • Sotsios Y. and Ward S. G. (2000): Phosphoinositide 3-kinase: a key biochemical signal for cell migration in response to chemokines. Immunol. Rev., 177, 217-235.
    • (2000) Immunol. Rev. , vol.177 , pp. 217-235
    • Sotsios, Y.1    Ward, S.G.2
  • 99
    • 0036493521 scopus 로고    scopus 로고
    • Soluble HLA class I molecules induce natural killer cell apoptosis through the engagement of CD8. Evidence for a negative regulation exerted by CD94/NKG2A complex and KIR2D
    • Spaggiari G. M., Contini P., Carosio R., Arvigo M., Ghio M., Oddone D., Dondero A., Zocchi M. R., Puppo F., Indiveri F. and Poggi A. (2002): Soluble HLA class I molecules induce natural killer cell apoptosis through the engagement of CD8. Evidence for a negative regulation exerted by CD94/NKG2A complex and KIR2D. Blood, 99, 1706-1714.
    • (2002) Blood , vol.99 , pp. 1706-1714
    • Spaggiari, G.M.1    Contini, P.2    Carosio, R.3    Arvigo, M.4    Ghio, M.5    Oddone, D.6    Dondero, A.7    Zocchi, M.R.8    Puppo, F.9    Indiveri, F.10    Poggi, A.11
  • 100
    • 0036891853 scopus 로고    scopus 로고
    • Soluble HLA class I induces NK cell apoptosis upon the engagement of killer-activating HLA class I receptors through FasL-Fas interaction
    • Spaggiari G. M., Contini P., Dondero A., Carosio R., Puppo F., Indiveri F., Zocchi M. R. and Poggi A. (2002): Soluble HLA class I induces NK cell apoptosis upon the engagement of killer-activating HLA class I receptors through FasL-Fas interaction. Blood, 100, 4098-4107.
    • (2002) Blood , vol.100 , pp. 4098-4107
    • Spaggiari, G.M.1    Contini, P.2    Dondero, A.3    Carosio, R.4    Puppo, F.5    Indiveri, F.6    Zocchi, M.R.7    Poggi, A.8
  • 102
    • 32644438233 scopus 로고    scopus 로고
    • Mesenchymal stem cell-natural killer cell interactions: Evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation
    • Spaggiari G. M., Capobianco A., Becchetti S., Mingari M. C. and Moretta L. (2006): Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation. Blood, 107, 1484-1490.
    • (2006) Blood , vol.107 , pp. 1484-1490
    • Spaggiari, G.M.1    Capobianco, A.2    Becchetti, S.3    Mingari, M.C.4    Moretta, L.5
  • 103
    • 0024792513 scopus 로고
    • Biology of natural killer cells
    • Trinchieri G. (1989): Biology of natural killer cells. Adv. Immunol., 47, 187-376.
    • (1989) Adv. Immunol. , vol.47 , pp. 187-376
    • Trinchieri, G.1
  • 104
  • 106
    • 16844362608 scopus 로고    scopus 로고
    • Mechanisms of suppression by suppressor T cells
    • Von Boehmer H. (2005): Mechanisms of suppression by suppressor T cells. Nat. Immunol., 6, 338-343.
    • (2005) Nat. Immunol. , vol.6 , pp. 338-343
    • Von Boehmer, H.1
  • 107
    • 0037204952 scopus 로고    scopus 로고
    • The Fas signalling pathway: More than a paradigm
    • Wajant H. (2002): The Fas signalling pathway: more than a paradigm. Science, 296, 1635-1636.
    • (2002) Science , vol.296 , pp. 1635-1636
    • Wajant, H.1
  • 108
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat and human bone marrow stromal cells differentiate into neurons
    • Woodbury D., Schwarz E. J., Prockop D. J. and Black I. B. (2000): Adult rat and human bone marrow stromal cells differentiate into neurons. J. Neurosci. Res., 61, 364-370.
    • (2000) J. Neurosci. Res. , vol.61 , pp. 364-370
    • Woodbury, D.1    Schwarz, E.J.2    Prockop, D.J.3    Black, I.B.4
  • 110
    • 0027447464 scopus 로고
    • Lymphocyte-endothelial cell adhesion molecules at the primary tumor site in humans
    • Zocchi M. R. and Poggi A. (1993): Lymphocyte-endothelial cell adhesion molecules at the primary tumor site in humans. J. Natl. Cancer Inst., 85, 246-247.
    • (1993) J. Natl. Cancer Inst. , vol.85 , pp. 246-247
    • Zocchi, M.R.1    Poggi, A.2
  • 111
    • 0027461411 scopus 로고
    • Adhesion of lymphocytes to vascular endothelium in LAD syndrome: Possible contribution of N-CAM
    • Zocchi M. R. and Poggi A.(1993): Adhesion of lymphocytes to vascular endothelium in LAD syndrome: possible contribution of N-CAM. Immunol. Today, 14, 94-95.
    • (1993) Immunol. Today , vol.14 , pp. 94-95
    • Zocchi, M.R.1    Poggi, A.2
  • 112
    • 18644380977 scopus 로고    scopus 로고
    • Pertussis toxin (PTX) B subunit and the non-toxic PTX mutant PT9K/129G inhibit TAT-induced TGF-β production by NK cells and TGF-β-mediated NK cell apoptosis
    • Zocchi M. R., Contini P., Alfano M. and Poggi A. (2005): Pertussis toxin (PTX) B subunit and the non-toxic PTX mutant PT9K/129G inhibit TAT-induced TGF-β production by NK cells and TGF-β-mediated NK cell apoptosis. J. Immunol., 174, 6054-6061.
    • (2005) J. Immunol. , vol.174 , pp. 6054-6061
    • Zocchi, M.R.1    Contini, P.2    Alfano, M.3    Poggi, A.4
  • 113
    • 20144368206 scopus 로고    scopus 로고
    • Role of gammadelta T lymphocytes in tumor defense
    • Zocchi M. R. and Poggi A. (2004): Role of gammadelta T lymphocytes in tumor defense. Frontiers Biosci., 9, 2588-2604.
    • (2004) Frontiers Biosci. , vol.9 , pp. 2588-2604
    • Zocchi, M.R.1    Poggi, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.