메뉴 건너뛰기




Volumn 17, Issue 2, 2005, Pages 163-169

Dendritic-cell-based therapeutic vaccination against cancer

Author keywords

[No Author keywords available]

Indexed keywords

CANCER VACCINE; CARCINOEMBRYONIC ANTIGEN; CD34 ANTIGEN; CD40 LIGAND; DENDRITIC CELL VACCINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

EID: 14844331400     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coi.2005.02.003     Document Type: Review
Times cited : (169)

References (67)
  • 1
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • J. Banchereau, and R.M. Steinman Dendritic cells and the control of immunity Nature 392 1998 245 252
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 2
    • 0034210006 scopus 로고    scopus 로고
    • Localization dose and time of antigens determine immune reactivity
    • R.M. Zinkernagel Localization dose and time of antigens determine immune reactivity Semin Immunol 12 2000 163 171 discussion 257-344
    • (2000) Semin Immunol , vol.12 , pp. 163-171
    • Zinkernagel, R.M.1
  • 3
    • 2442647551 scopus 로고    scopus 로고
    • Dendritic cell immunotherapy: Mapping the way
    • th International Expert Meeting on Clinical Dendritic Cell Therapy in Amsterdam. Extensive supplementary tables provide a good overview of currently ongoing DC vaccination trials.
    • (2004) Nat Med , vol.10 , pp. 475-480
    • Figdor, C.G.1    De Vries, I.J.2    Lesterhuis, W.J.3    Melief, C.J.4
  • 4
    • 0345863802 scopus 로고    scopus 로고
    • Dendritic cells in tumor immunology and immunotherapy
    • C.J. Turtle, and D.N. Hart Dendritic cells in tumor immunology and immunotherapy Curr Drug Targets 5 2004 17 39
    • (2004) Curr Drug Targets , vol.5 , pp. 17-39
    • Turtle, C.J.1    Hart, D.N.2
  • 5
    • 0041302136 scopus 로고    scopus 로고
    • Dendritic cell-based cancer immunotherapy
    • E.G. Engleman Dendritic cell-based cancer immunotherapy Semin Oncol 30 2003 23 29
    • (2003) Semin Oncol , vol.30 , pp. 23-29
    • Engleman, E.G.1
  • 6
    • 0038685269 scopus 로고    scopus 로고
    • Dendritic cells and immunotherapy for cancer
    • D.H. Chang, and M.V. Dhodapkar Dendritic cells and immunotherapy for cancer Int J Hematol 77 2003 439 443
    • (2003) Int J Hematol , vol.77 , pp. 439-443
    • Chang, D.H.1    Dhodapkar, M.V.2
  • 8
    • 4944223122 scopus 로고    scopus 로고
    • Manipulating dendritic cell biology for the active immunotherapy of cancer
    • D.W. O'Neill, S. Adams, and N. Bhardwaj Manipulating dendritic cell biology for the active immunotherapy of cancer Blood 104 2004 2235 2246
    • (2004) Blood , vol.104 , pp. 2235-2246
    • O'Neill, D.W.1    Adams, S.2    Bhardwaj, N.3
  • 9
    • 0041825328 scopus 로고    scopus 로고
    • Dendritic cell-based cancer therapy
    • C. Conrad, and F.O. Nestle Dendritic cell-based cancer therapy Curr Opin Mol Ther 5 2003 405 412
    • (2003) Curr Opin Mol Ther , vol.5 , pp. 405-412
    • Conrad, C.1    Nestle, F.O.2
  • 10
    • 0034918104 scopus 로고    scopus 로고
    • Dendritic cells: On the move from bench to bedside
    • F.O. Nestle, J. Banchereau, and D. Hart Dendritic cells: On the move from bench to bedside Nat Med 7 2001 761 765
    • (2001) Nat Med , vol.7 , pp. 761-765
    • Nestle, F.O.1    Banchereau, J.2    Hart, D.3
  • 11
    • 0346096827 scopus 로고    scopus 로고
    • The first 1000 dendritic cell vaccinees
    • D. Ridgway The first 1000 dendritic cell vaccinees Cancer Invest 21 2003 873 886
    • (2003) Cancer Invest , vol.21 , pp. 873-886
    • Ridgway, D.1
  • 12
    • 3042722266 scopus 로고    scopus 로고
    • Immunotherapy: Bewitched, bothered, and bewildered no more
    • R.M. Steinman, and I. Mellman Immunotherapy: bewitched, bothered, and bewildered no more Science 305 2004 197 200
    • (2004) Science , vol.305 , pp. 197-200
    • Steinman, R.M.1    Mellman, I.2
  • 13
    • 4644293572 scopus 로고    scopus 로고
    • Cancer immunotherapy: Breaking the barriers to harvest the crop
    • D. Pardoll, and J. Allison Cancer immunotherapy: breaking the barriers to harvest the crop Nat Med 10 2004 887 892 Together with [12], this key paper discusses the demands of human research, including cancer immunotherapy, and calls for better support of the academic investigator as they navigate the pathways from laboratory to clinic.
    • (2004) Nat Med , vol.10 , pp. 887-892
    • Pardoll, D.1    Allison, J.2
  • 14
    • 19444373631 scopus 로고    scopus 로고
    • Maturation matters: Importance of maturation for antitumor immunity of dendritic cell vaccines
    • S. Adams, D. O'Neill, and N. Bhardwaj Maturation matters: importance of maturation for antitumor immunity of dendritic cell vaccines J Clin Oncol 22 2004 3834 3835 author reply 3835
    • (2004) J Clin Oncol , vol.22 , pp. 3834-3835
    • Adams, S.1    O'Neill, D.2    Bhardwaj, N.3
  • 16
  • 17
    • 0035383783 scopus 로고    scopus 로고
    • Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer
    • P. Kalinski, P.L. Vieira, J.H. Schuitemaker, E.C. de Jong, and M.L. Kapsenberg Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer Blood 97 2001 3466 3469
    • (2001) Blood , vol.97 , pp. 3466-3469
    • Kalinski, P.1    Vieira, P.L.2    Schuitemaker, J.H.3    De Jong, E.C.4    Kapsenberg, M.L.5
  • 18
    • 0034305809 scopus 로고    scopus 로고
    • Kinetics of dendritic cell activation: Impact on priming of TH1, TH2 and nonpolarized T cells
    • A. Langenkamp, M. Messi, A. Lanzavecchia, and F. Sallusto Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells Nat Immunol 1 2000 311 316
    • (2000) Nat Immunol , vol.1 , pp. 311-316
    • Langenkamp, A.1    Messi, M.2    Lanzavecchia, A.3    Sallusto, F.4
  • 19
    • 17144443360 scopus 로고    scopus 로고
    • Cascades of transcriptional induction during dendritic cell maturation revealed by genome-wide expression analysis
    • O. Tureci, H. Bian, F.O. Nestle, L. Raddrizzani, J.A. Rosinski, A. Tassis, H. Hilton, M. Walstead, U. Sahin, and J. Hammer Cascades of transcriptional induction during dendritic cell maturation revealed by genome-wide expression analysis FASEB J 17 2003 836 847 This paper demonstrates the plasticity of DC differentiation on the transcriptome level, emphasizing the importance of timing of the maturation stimuli.
    • (2003) FASEB J , vol.17 , pp. 836-847
    • Tureci, O.1    Bian, H.2    Nestle, F.O.3    Raddrizzani, L.4    Rosinski, J.A.5    Tassis, A.6    Hilton, H.7    Walstead, M.8    Sahin, U.9    Hammer, J.10
  • 24
    • 2942644555 scopus 로고    scopus 로고
    • Expansion of melanoma-specific cytolytic CD8+ T cell precursors in patients with metastatic melanoma vaccinated with CD34+ progenitor-derived dendritic cells
    • S. Paczesny, J. Banchereau, K.M. Wittkowski, G. Saracino, J. Fay, and A.K. Palucka Expansion of melanoma-specific cytolytic CD8+ T cell precursors in patients with metastatic melanoma vaccinated with CD34+ progenitor-derived dendritic cells J Exp Med 199 2004 1503 1511
    • (2004) J Exp Med , vol.199 , pp. 1503-1511
    • Paczesny, S.1    Banchereau, J.2    Wittkowski, K.M.3    Saracino, G.4    Fay, J.5    Palucka, A.K.6
  • 25
    • 0141818346 scopus 로고    scopus 로고
    • Single injection of CD34+ progenitor-derived dendritic cell vaccine can lead to induction of T-cell immunity in patients with stage IV melanoma
    • A.K. Palucka, M.V. Dhodapkar, S. Paczesny, S. Burkeholder, K.M. Wittkowski, R.M. Steinman, J. Fay, and J. Banchereau Single injection of CD34+ progenitor-derived dendritic cell vaccine can lead to induction of T-cell immunity in patients with stage IV melanoma J Immunother 26 2003 432 439
    • (2003) J Immunother , vol.26 , pp. 432-439
    • Palucka, A.K.1    Dhodapkar, M.V.2    Paczesny, S.3    Burkeholder, S.4    Wittkowski, K.M.5    Steinman, R.M.6    Fay, J.7    Banchereau, J.8
  • 26
    • 0347915734 scopus 로고    scopus 로고
    • Freeze-thawing procedures have no influence on the phenotypic and functional development of dendritic cells generated from peripheral blood CD14+ monocytes
    • S. Hori, Y. Heike, M. Takei, M. Maruyama, Y. Inoue, J.J. Lee, H.J. Kim, Y. Harada, H. Kawai, and A. Shimosaka Freeze-thawing procedures have no influence on the phenotypic and functional development of dendritic cells generated from peripheral blood CD14+ monocytes J Immunother 27 2004 27 35
    • (2004) J Immunother , vol.27 , pp. 27-35
    • Hori, S.1    Heike, Y.2    Takei, M.3    Maruyama, M.4    Inoue, Y.5    Lee, J.J.6    Kim, H.J.7    Harada, Y.8    Kawai, H.9    Shimosaka, A.10
  • 27
    • 0344211832 scopus 로고    scopus 로고
    • Cryopreservation of mature monocyte-derived human dendritic cells for vaccination: Influence on phenotype and functional properties
    • J. Westermann, I.J. Korner, J. Kopp, S. Kurz, M. Zenke, B. Dorken, and A. Pezzutto Cryopreservation of mature monocyte-derived human dendritic cells for vaccination: influence on phenotype and functional properties Cancer Immunol Immunother 52 2003 194 198
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 194-198
    • Westermann, J.1    Korner, I.J.2    Kopp, J.3    Kurz, S.4    Zenke, M.5    Dorken, B.6    Pezzutto, A.7
  • 30
    • 0242574478 scopus 로고    scopus 로고
    • A protocol for generation of clinical grade mRNA-transfected monocyte-derived dendritic cells for cancer vaccines
    • L.J. Mu, G. Gaudernack, S. Saeboe-Larssen, H. Hammerstad, A. Tierens, and G. Kvalheim A protocol for generation of clinical grade mRNA-transfected monocyte-derived dendritic cells for cancer vaccines Scand J Immunol 58 2003 578 586
    • (2003) Scand J Immunol , vol.58 , pp. 578-586
    • Mu, L.J.1    Gaudernack, G.2    Saeboe-Larssen, S.3    Hammerstad, H.4    Tierens, A.5    Kvalheim, G.6
  • 33
    • 0142152437 scopus 로고    scopus 로고
    • Dendritic cell culture: A simple closed culture system using ficoll, monocytes, and a table-top centrifuge
    • C.M. Celluzzi, and C. Welbon Dendritic cell culture: a simple closed culture system using ficoll, monocytes, and a table-top centrifuge J Hematother Stem Cell Res 12 2003 575 585
    • (2003) J Hematother Stem Cell Res , vol.12 , pp. 575-585
    • Celluzzi, C.M.1    Welbon, C.2
  • 34
    • 0037106006 scopus 로고    scopus 로고
    • Large-scale monocyte enrichment coupled with a closed culture system for the generation of human dendritic cells
    • V. Pullarkat, R. Lau, S.M. Lee, J.G. Bender, and J.S. Weber Large-scale monocyte enrichment coupled with a closed culture system for the generation of human dendritic cells J Immunol Methods 267 2002 173 183
    • (2002) J Immunol Methods , vol.267 , pp. 173-183
    • Pullarkat, V.1    Lau, R.2    Lee, S.M.3    Bender, J.G.4    Weber, J.S.5
  • 35
    • 1542327598 scopus 로고    scopus 로고
    • Monitoring tumor antigen specific T-cell responses in cancer patients and phase I clinical trials of peptide-based vaccination
    • P. Romero, J.C. Cerottini, and D.E. Speiser Monitoring tumor antigen specific T-cell responses in cancer patients and phase I clinical trials of peptide-based vaccination Cancer Immunol Immunother 53 2004 249 255 Essential reading on the state of the art of immune monitoring.
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 249-255
    • Romero, P.1    Cerottini, J.C.2    Speiser, D.E.3
  • 36
    • 0344585451 scopus 로고    scopus 로고
    • Dendritic cells charged with apoptotic tumor cells induce long-lived protective CD4+ and CD8+ T cell immunity against B16 melanoma
    • R.S. Goldszmid, J. Idoyaga, A.I. Bravo, R. Steinman, J. Mordoh, and R. Wainstok Dendritic cells charged with apoptotic tumor cells induce long-lived protective CD4+ and CD8+ T cell immunity against B16 melanoma J Immunol 171 2003 5940 5947
    • (2003) J Immunol , vol.171 , pp. 5940-5947
    • Goldszmid, R.S.1    Idoyaga, J.2    Bravo, A.I.3    Steinman, R.4    Mordoh, J.5    Wainstok, R.6
  • 37
    • 1942520384 scopus 로고    scopus 로고
    • Phenotype and functional analysis of human monocyte-derived dendritic cells loaded with biodegradable poly(lactide-co-glycolide) microspheres for immunotherapy
    • Y. Waeckerle-Men, E. Scandella, E. Uetz-Von Allmen, B. Ludewig, S. Gillessen, H.P. Merkle, B. Gander, and M. Groettrup Phenotype and functional analysis of human monocyte-derived dendritic cells loaded with biodegradable poly(lactide-co-glycolide) microspheres for immunotherapy J Immunol Methods 287 2004 109 124
    • (2004) J Immunol Methods , vol.287 , pp. 109-124
    • Waeckerle-Men, Y.1    Scandella, E.2    Uetz-Von Allmen, E.3    Ludewig, B.4    Gillessen, S.5    Merkle, H.P.6    Gander, B.7    Groettrup, M.8
  • 41
    • 0142055970 scopus 로고    scopus 로고
    • Intranodal administration of peptide-pulsed mature dendritic cell vaccines results in superior CD8+ T-cell function in melanoma patients
    • I. Bedrosian, R. Mick, S. Xu, H. Nisenbaum, M. Faries, P. Zhang, P.A. Cohen, G. Koski, and B.J. Czerniecki Intranodal administration of peptide-pulsed mature dendritic cell vaccines results in superior CD8+ T-cell function in melanoma patients J Clin Oncol 21 2003 3826 3835 This is the first paper to compare, in a comprehensive fashion, intranodal, intradermal and intravenous injection of mature DCs into cancer patients.
    • (2003) J Clin Oncol , vol.21 , pp. 3826-3835
    • Bedrosian, I.1    Mick, R.2    Xu, S.3    Nisenbaum, H.4    Faries, M.5    Zhang, P.6    Cohen, P.A.7    Koski, G.8    Czerniecki, B.J.9
  • 43
    • 0345447557 scopus 로고    scopus 로고
    • Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation
    • S. Nair, C. McLaughlin, A. Weizer, Z. Su, D. Boczkowski, J. Dannull, J. Vieweg, and E. Gilboa Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation J Immunol 171 2003 6275 6282
    • (2003) J Immunol , vol.171 , pp. 6275-6282
    • Nair, S.1    McLaughlin, C.2    Weizer, A.3    Su, Z.4    Boczkowski, D.5    Dannull, J.6    Vieweg, J.7    Gilboa, E.8
  • 44
    • 0042922810 scopus 로고    scopus 로고
    • Regulation of dendritic cell migration to the draining lymph node: Impact on T lymphocyte traffic and priming
    • A. MartIn-Fontecha, S. Sebastiani, U.E. Hopken, M. Uguccioni, M. Lipp, A. Lanzavecchia, and F. Sallusto Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming J Exp Med 198 2003 615 621 Together with [43], this paper introduces the concept of 'in situ maturation' of dendritic cells.
    • (2003) J Exp Med , vol.198 , pp. 615-621
    • Martin-Fontecha, A.1    Sebastiani, S.2    Hopken, U.E.3    Uguccioni, M.4    Lipp, M.5    Lanzavecchia, A.6    Sallusto, F.7
  • 46
    • 0141720611 scopus 로고    scopus 로고
    • Induction of an antitumor immunological response by an intratumoral injection of dendritic cells pulsed with genetically engineered Semliki Forest virus to produce interleukin-18 combined with the systemic administration of interleukin-12
    • R. Yamanaka, N. Tsuchiya, N. Yajima, J. Honma, H. Hasegawa, R. Tanaka, J. Ramsey, R.M. Blaese, and K.G. Xanthopoulos Induction of an antitumor immunological response by an intratumoral injection of dendritic cells pulsed with genetically engineered Semliki Forest virus to produce interleukin-18 combined with the systemic administration of interleukin-12 J Neurosurg 99 2003 746 753
    • (2003) J Neurosurg , vol.99 , pp. 746-753
    • Yamanaka, R.1    Tsuchiya, N.2    Yajima, N.3    Honma, J.4    Hasegawa, H.5    Tanaka, R.6    Ramsey, J.7    Blaese, R.M.8    Xanthopoulos, K.G.9
  • 47
    • 0037337629 scopus 로고    scopus 로고
    • Intratumoral dendritic cell vaccination elicits potent tumoricidal immunity against malignant glioma in rats
    • M. Ehtesham, P. Kabos, M.A. Gutierrez, K. Samoto, K.L. Black, and J.S. Yu Intratumoral dendritic cell vaccination elicits potent tumoricidal immunity against malignant glioma in rats J Immunother 26 2003 107 116
    • (2003) J Immunother , vol.26 , pp. 107-116
    • Ehtesham, M.1    Kabos, P.2    Gutierrez, M.A.3    Samoto, K.4    Black, K.L.5    Yu, J.S.6
  • 48
    • 0345865089 scopus 로고    scopus 로고
    • Dendritic cells: A journey from laboratory to clinic
    • V. Cerundolo, I.F. Hermans, and M. Salio Dendritic cells: a journey from laboratory to clinic Nat Immunol 5 2004 7 10
    • (2004) Nat Immunol , vol.5 , pp. 7-10
    • Cerundolo, V.1    Hermans, I.F.2    Salio, M.3
  • 49
    • 0642311904 scopus 로고    scopus 로고
    • Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells
    • C.L. Slingluff Jr., G.R. Petroni, G.V. Yamshchikov, D.L. Barnd, S. Eastham, H. Galavotti, J.W. Patterson, D.H. Deacon, S. Hibbitts, and D. Teates Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells J Clin Oncol 21 2003 4016 4026
    • (2003) J Clin Oncol , vol.21 , pp. 4016-4026
    • Slingluff Jr., C.L.1    Petroni, G.R.2    Yamshchikov, G.V.3    Barnd, D.L.4    Eastham, S.5    Galavotti, H.6    Patterson, J.W.7    Deacon, D.H.8    Hibbitts, S.9    Teates, D.10
  • 54
    • 0037968644 scopus 로고    scopus 로고
    • Intranodal injection of semimature monocyte-derived dendritic cells induces T helper type 1 responses to protein neoantigen
    • M. Gilliet, M. Kleinhans, E. Lantelme, D. Schadendorf, G. Burg, and F.O. Nestle Intranodal injection of semimature monocyte-derived dendritic cells induces T helper type 1 responses to protein neoantigen Blood 102 2003 36 42 First human in vivo study providing a detailed analysis of the helper T cell response occurring after intranodal injection of neo-protein (i.e. keyhole limpet hemocyanin) pulsed DCs.
    • (2003) Blood , vol.102 , pp. 36-42
    • Gilliet, M.1    Kleinhans, M.2    Lantelme, E.3    Schadendorf, D.4    Burg, G.5    Nestle, F.O.6
  • 56
    • 0036735859 scopus 로고    scopus 로고
    • Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs
    • S. Fujii, K. Shimizu, M. Kronenberg, and R.M. Steinman Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs Nat Immunol 3 2002 867 874
    • (2002) Nat Immunol , vol.3 , pp. 867-874
    • Fujii, S.1    Shimizu, K.2    Kronenberg, M.3    Steinman, R.M.4
  • 57
    • 0037437909 scopus 로고    scopus 로고
    • Detection and activation of human Valpha24+ natural killer T cells using alpha-galactosyl ceramide-pulsed dendritic cells
    • S. Fujii, K. Shimizu, R.M. Steinman, and M.V. Dhodapkar Detection and activation of human Valpha24+ natural killer T cells using alpha-galactosyl ceramide-pulsed dendritic cells J Immunol Methods 272 2003 147 159
    • (2003) J Immunol Methods , vol.272 , pp. 147-159
    • Fujii, S.1    Shimizu, K.2    Steinman, R.M.3    Dhodapkar, M.V.4
  • 58
    • 0942276861 scopus 로고    scopus 로고
    • Therapeutic activation of Valpha24+Vbeta11+ NKT cells in human subjects results in highly coordinated secondary activation of acquired and innate immunity
    • M. Nieda, M. Okai, A. Tazbirkova, H. Lin, A. Yamaura, K. Ide, R. Abraham, T. Juji, D.J. Macfarlane, and A.J. Nicol Therapeutic activation of Valpha24+Vbeta11+ NKT cells in human subjects results in highly coordinated secondary activation of acquired and innate immunity Blood 103 2004 383 389
    • (2004) Blood , vol.103 , pp. 383-389
    • Nieda, M.1    Okai, M.2    Tazbirkova, A.3    Lin, H.4    Yamaura, A.5    Ide, K.6    Abraham, R.7    Juji, T.8    MacFarlane, D.J.9    Nicol, A.J.10
  • 59
    • 12144286596 scopus 로고    scopus 로고
    • In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination
    • L.C. Bonifaz, D.P. Bonnyay, A. Charalambous, D.I. Darguste, S. Fujii, H. Soares, M.K. Brimnes, B. Moltedo, T.M. Moran, and R.M. Steinman In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination J Exp Med 199 2004 815 824 This key study defines for the first time the requirements of DC targeting using DEC-205 for T-cell vaccination.
    • (2004) J Exp Med , vol.199 , pp. 815-824
    • Bonifaz, L.C.1    Bonnyay, D.P.2    Charalambous, A.3    Darguste, D.I.4    Fujii, S.5    Soares, H.6    Brimnes, M.K.7    Moltedo, B.8    Moran, T.M.9    Steinman, R.M.10
  • 61
    • 0036812719 scopus 로고    scopus 로고
    • Effective therapeutic anticancer vaccines based on precision guiding of cytolytic T lymphocytes
    • C.J. Melief, S.H. Van Der Burg, R.E. Toes, F. Ossendorp, and R. Offringa Effective therapeutic anticancer vaccines based on precision guiding of cytolytic T lymphocytes Immunol Rev 188 2002 177 182
    • (2002) Immunol Rev , vol.188 , pp. 177-182
    • Melief, C.J.1    Van Der Burg, S.H.2    Toes, R.E.3    Ossendorp, F.4    Offringa, R.5
  • 62
    • 1842486876 scopus 로고    scopus 로고
    • Induction of potent antitumor immunity by in situ targeting of intratumoral DCs
    • K. Furumoto, L. Soares, E.G. Engleman, and M. Merad Induction of potent antitumor immunity by in situ targeting of intratumoral DCs J Clin Invest 113 2004 774 783
    • (2004) J Clin Invest , vol.113 , pp. 774-783
    • Furumoto, K.1    Soares, L.2    Engleman, E.G.3    Merad, M.4
  • 63
    • 0041530710 scopus 로고    scopus 로고
    • Vaccination of cutaneous T-cell lymphoma patients using intranodal injection of autologous tumor lysate pulsed dendritic cells
    • T. Maier, A. Tun-Kyi, A. Tassis, K.P. Jungius, G. Burg, R. Dummer, and F.O. Nestle Vaccination of cutaneous T-cell lymphoma patients using intranodal injection of autologous tumor lysate pulsed dendritic cells Blood 102 2003 2338 2344 This is the first demonstration of clinical as well as immunological responses in selected patients with cutaneous T-cell lymphoma (CTCL). CTCL is an interesting tumor for vaccination therapy due to its slow course, the clearly visible skin tumors and defined molecular endpoints. This tumor allows the unique opportunity to establish a correlation between vaccine application and tumor response.
    • (2003) Blood , vol.102 , pp. 2338-2344
    • Maier, T.1    Tun-Kyi, A.2    Tassis, A.3    Jungius, K.P.4    Burg, G.5    Dummer, R.6    Nestle, F.O.7
  • 64
    • 0043245914 scopus 로고    scopus 로고
    • Synergy between tumor immunotherapy and antiangiogenic therapy
    • S. Nair, D. Boczkowski, B. Moeller, M. Dewhirst, J. Vieweg, and E. Gilboa Synergy between tumor immunotherapy and antiangiogenic therapy Blood 102 2003 964 971 The authors of this study introduce the concept of combining tumor immunotherapy with anti-angiogenic therapy using RNA-pulsed DCs.
    • (2003) Blood , vol.102 , pp. 964-971
    • Nair, S.1    Boczkowski, D.2    Moeller, B.3    Dewhirst, M.4    Vieweg, J.5    Gilboa, E.6
  • 65
    • 0037154222 scopus 로고    scopus 로고
    • Tumor lysate-pulsed dendritic cells can elicit an effective antitumor immune response during early lymphoid recovery
    • W. Asavaroengchai, Y. Kotera, and J.J. Mule Tumor lysate-pulsed dendritic cells can elicit an effective antitumor immune response during early lymphoid recovery Proc Natl Acad Sci USA 99 2002 931 936
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 931-936
    • Asavaroengchai, W.1    Kotera, Y.2    Mule, J.J.3
  • 66
    • 0344341626 scopus 로고    scopus 로고
    • Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
    • F.S. Hodi, M.C. Mihm, R.J. Soiffer, F.G. Haluska, M. Butler, M.V. Seiden, T. Davis, R. Henry-Spires, S. MacRae, and A. Willman Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients Proc Natl Acad Sci USA 100 2003 4712 4717 This is a key paper showing the biological effects, in previously vaccinated cancer patients (including patients vaccinated with DCs) of CTLA-4 antibody blockade.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4712-4717
    • Hodi, F.S.1    Mihm, M.C.2    Soiffer, R.J.3    Haluska, F.G.4    Butler, M.5    Seiden, M.V.6    Davis, T.7    Henry-Spires, R.8    MacRae, S.9    Willman, A.10
  • 67
    • 1642321113 scopus 로고    scopus 로고
    • Revival of the regulatory T cell: New targets for drug development
    • R.P. Sutmuller, R. Offringa, and C.J. Melief Revival of the regulatory T cell: new targets for drug development Drug Discov Today 9 2004 310 316
    • (2004) Drug Discov Today , vol.9 , pp. 310-316
    • Sutmuller, R.P.1    Offringa, R.2    Melief, C.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.