Isoquinoline-1,3,4-trione and its derivatives attenuate β-amyloid-induced apoptosis of neuronal cells

FEBS Journal

Volumn 273, Issue 21, 2006, Pages 4842-4852

  Zhang, Ya Hui ^a   Zhang, Hua Jie ^a   Wu, Fang ^a   Chen, Yi Hua ^a   Ma, Xue Qin ^b   Du, Jun Qin ^a   Zhou, Zhong Liang ^b   Li, Jing Ya ^a   Nan, Fa Jun ^a,c   Li, Jia ^a,c  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b EAST CHINA NORMAL UNIVERSITY   (China)

^c NONE   (China)

Author keywords

amyloid; Attenuate apoptosis; Caspase 3 inhibitor; Irreversible; Neuronal cell

Indexed keywords

3 [2 [(2 TERT BUTYLPHENYLAMINOOXALYL)AMINO]PROPIONYLAMINO] 4 OXO 5 (2,3,5,6 TETRAFLUOROPHENOXY)PENTANOIC ACID; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[25-35]; CASPASE 3; CASPASE 3 INHIBITOR; ISATIN; ISOQUINOLINE 1,3, TRIONE DERIVATIVE; ISOQUINOLINE 1,3,4 TRIONE; ISOQUINOLINE DERIVATIVE; M 791; PRALNACASAN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CATALYSIS; CELL STRAIN; CONTROLLED STUDY; DEGENERATIVE DISEASE; DRUG PROTEIN BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; NERVE CELL CULTURE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN; ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; CELL SURVIVAL; CELLS, CULTURED; HUMANS; ISOQUINOLINES; NEURONS; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33750073168     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2006.05483.x     Document Type: Article

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