Murine subtilisin-like proteinase SPC6 is expressed during embryonic implantation, somitogenesis, and skeletal formation

Developmental Genetics

Volumn 21, Issue 1, 1997, Pages 75-81

  Rancourt, Susan L ^b   Rancourt, Derrick E ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b NONE

Author keywords

Implantation; Prohormone convertase; Skeletogenesis; Somitogenesis; SPC6

Indexed keywords

HORMONE PRECURSOR; MATRIX METALLOPROTEINASE; PROTEINASE; SUBTILISIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BRAIN MATURATION; EMBRYO DEVELOPMENT; ENZYME LOCALIZATION; IN SITU HYBRIDIZATION; MOLECULAR CLONING; MOUSE; NIDATION; NONHUMAN; PRIORITY JOURNAL; SOMITE;

ANIMALS; BONE AND BONES; EMBRYO IMPLANTATION; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; MICE; MORPHOGENESIS; POLYMERASE CHAIN REACTION; PREGNANCY; PROPROTEIN CONVERTASE 5; SOMITES; SUBTILISINS;

ANIMALIA; MAMMALIA; MURINAE;

EID: 0030768885     PISSN: 0192253X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6408(1997)21:1<75::AID-DVG9>3.0.CO;2-5     Document Type: Article

References (46)

1. Alexander CM, Hansell EJ, Behrendsen O, Flannery ML, Kishnani NS, Hawkes SP, Werb Z (1996): Expression and function of matrix metalloproteinases and their inhibitors at the maternal-embryonic boundary during mouse embryo implantation. Development 123: 1723-1736.
2. Barr PJ (1991): Mammalian subtilisins: The long-sought dibasic processing endoproteases. Cell 66:1-3.
3. Collignon J, Varlet I, Robertson EJ (1996): Relationship between asymmetric nodal expression and the direction of embryonic turning. Nature 381:155-161.
4. Constam DB, Calfon M, Robertson EJ (1996): SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distant sites during embryogenesis. J Cell Biol 134:181-191.
5. Cross JC, Werb Z, Fisher SJ (1994): Implantation and the placenta: Key pieces of the development puzzle. Science 266:1508-1518.
6. Dubois CM, Laprise MH, Blanchette F, Gentry LE, Leduc R (1995): Processing of transforming growth factor β1 precursor by human furin convertase. J Biol Chem 270:10618-10624.
7. Fahrner K, Hogan BL, Flavell RA (1987): Transcription of H-2 and Qa genes in embryonic and adult mice. EMBO J 6:1265-1271.
8. Fricker LD (1988): Carboxypeptidase E. Annu Rev Physiol 50:309-321.
9. Graham CH, Lala PK (1991): Mechanism of control of trophoblast invasion in situ. J Cell Physiol 148:228-234.
10. Graham CH, Lala PK (1992): Mechanisms of placental invasion of the uterus and their control. Biochem Cell Biol 70:867-874.
11. Harvey MB, Leco KJ, Arcellana-Panlilio MY, Zhang X, Edwards DR, Schultz GA (1995a): Roles of growth factors during peri-implantation development. Mol Hum Reprod 10:712-718.
12. Harvey MB, Leco KJ, Arcellana-Panlilio MY, Zhang X, Edwards DR, Schultz GA (1995b): Proteinase expression in early mouse embryos is regulated by leukemia inhibitory factor and epidermal growth factor. Development 121:1005-1014.
13. Hishida R, Ishihara T, Kondo K, Katsura I (1996): hch-1, a gene required for normal hatching and normal migration of a neuroblast in C. elegans, encodes a protein related to TOLLOID and BMP-1. EMBO J 15:4111-4122.
14. Hogan BL (1996): Bone morphogenetic proteins: Multifunctional regulators of vertebrate development. Genes Dev 10:1580-1594.
15. Hook VY, Azaryan AV, Hwang S-R, Tezapsidis N (1994): Proteases and the emerging role of protease inhibitors in prohormone processing. FASEB J 8:1269-1278.
16. Jones CM, Lyons KM, Hogan BLM (1991): Involvement of bone morphogenetic protein (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse. Development 111:531-542.
17. Kessler DS, Melton DA (1995): Induction of dorsal mesoderm by soluble, mature Vg1 protein. Development 121:2155-2164.
18. Leco KJ, Khokha R, Pavloff N, Hawkes SP, Edwards DR (1994): Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues. J Biol Chem 269:9352-9360.
19. Leco KJ, Edwards DR, Schultz GA (1996): Tissue inhibitor of metalloproteinases-3 is the major metalloproteinase inhibitor in the decidualizing murine uterus. Mol Reprod Dev 45:458-465.
20. Lepage T, Ghiglione C, Gache C (1992): Spatial and temporal expression pattern during sea urchin embryogenesis of a gene coding for a protease holologous to the human BMP-1 and to the product of Drosophila dorsal-ventral patterning gene tolloid. Development 114:147-163.
21. Lusson J, Vieau D, Hamelin J, Day R, Chretien M, Seidah NG (1993): cDNA structure of the mouse and rat subtilisin/kexin-like PC5: A candidate proprotein convertase expressed in endocrine and nonendocrine cells. Proc Natl Acad Sci USA 90:6691-6695.
22. Lyons KM, Pelton RW, Hogan BLM (1990): Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A). Development 109:833-844.
23. Lysiak JJ, Hunt J, Pringle GA, Lala PK (1995): Localization of transforming growth factor β and its natural inhibitor decorin in the human placenta and decidua throughout gestation. Placenta 16:221-231.
24. Manley NR, Capecchi MR (1995): The role of Hoxa-3 in mouse thymus and thyroid development. Development 121:1989-2003.
25. Manova K, Paynton BV, Bachvarova RF (1992): Expression of activins and TGFβ1 and β2 RNAs in early postimplantation mouse embryos and uterine decidua. Mech Dev 36:141-152.
26. Massague J, Attisano L, Wrana JL (1994): The TGFβ family and its composite receptors. Trends Cell Biol 4:172-178.
27. Matrisian LM (1992): The matrix-degrading metalloproteinases. Bioessays 14:455-463.
28. Meno C, Saijoh Y, Hideta F, Ikeda M, Yokoyama T, Yokoyama M, Toyoda Y, Hamada H (1996): Left-right asymmetric expression of the TGFβ-family member lefty in mouse embryos. Nature 381:151-155.
29. Nachtigal MW, Ingraham HA (1996): Bioactivation of Mullerian inhibitory substance during gonada development by a kex2/subtilisin-like endoprotease. Proc Natl Acad Sci USA 93:7711-7716.
30. Nakagawa T, Hosaka M, Torii S, Watanabe T, Murakami K, Nakayama K (1993a): Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: Its striking structual similarity to PACE4. J Biochem 113:132-135.
31. Nakagawa T, Murakami K, Kazuhis N (1993b): Identification of an isoform with an extremely large Cys-rich region of PC6, a Kex2-like processing endoprotease. FEBS Lett 327:165-171.
32. Nguyen T, Jamal J, Shimell MJ, Arora K, O'Connor MB (1994): Characterization of tolloid-related-1: A BMP-1-like product that is required during larval and pupal stages of Drosophila development. Dev Biol 166:569-586.
33. Padgett RW, Wozney JM, Gelbart WM (1993): Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo. Proc Natl Acad Sci USA 90:2905-2909.
34. Pei D, Weiss SJ (1995): Furin-dependent intracellular activation of the human stromelysin-3 zymogen. Nature 375:244-247.
35. Roebroek AJ, Creemers JWM, Pauli IGL, Bogaert T, Van de Ven WJM (1993): Generation of structural and functional diversity in furin-like proteins in Drosophila melanogaster by alternative splicing of the Dfur1 gene. EMBO J 12:1853-1870.
36. Roelen BAJ, Lin HY, Knezevic V, Freund E, Mummery CL (1994): Expression of TGF-βs and their receptors during implantation and organogenesis of the mouse embryo. Dev Biol 166:716-728.
37. Sambrook J, Fritsch EF, Maniatis T (1989): "Molecular Cloning: A Laboratory Manual, 2nd Edition." Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
38. Sarras MP (1996): BMP-1 and the astacin family of metalloproteinases: A potential link between the extracellular matrix, growth factors and pattern formation. Bioessays 18:439-442.
39. Seidah NG, Chretien M (1994): Pro-protein convertases of subtilisin/ kexin family. Methods Enzymol 244:175-188.
40. Seidah NG, Hamelin J, Mamarbachi M, Dong W, Tardos H, Mbikay M, Chreitien M, Day R (1996): cDNA structure, tissue distribution and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases. Proc Natl Acad Sci USA 93:3388-3393.
41. Steiner DF, Smeekens SP, Ohagi S, Chan SJ (1992): The new enzymology of precursor processing endoproteases. J Biol Chem 267:23435-23438.
42. Thacker CT, Peters M, Strayko M, Rose AM (1995): The bli-4 locus of Caenorhabditis elegans encodes structurally distinct kex2/subtilisin-like endoproteases essential for early development and adult morphology. Genes Dev 9:956-971.
43. Winnier G, Blessing M, Labosky PA, Hogan BLM (1995): Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev 9:2105-2116.
44. Wozney JM, Rosen V, Celeste AJ, Mitsock LM, Whitters MJ, Kriz RW, Hewick RM, Wang EA (1988): Novel regulators of bone formation: Molecular clones and activities. Science 242:1528-1534.
45. Wuthrich M, Creemers JWM, Van de Ven WJM, Sterchi EE (1996): Human lactase-phlorizin hydrolase is not processed by furin, PC1/ PC3, PC2, PACE4 and PC5/PC6A of the family of subtilisin-like proprotein processing proteases. Biochim Biophys Acta 1311:199-203.
46. Zheng M, Streck RD, Scott RE, Seidah NG, Pintar JE (1994): The developmental expression in rat of proteases furin, PC1, PC2, and carboxypeptidase E: Implications for early maturation of proteolytic processing capacity. J Neurosci 14:4656-4673.