메뉴 건너뛰기




Volumn 54, Issue 7, 2006, Pages 375-386

The metabolic syndrome

Author keywords

Adipose tissue; Aging innate immunity; Cytokines; Inflammation; Insulin resistance; Obesity

Indexed keywords

ACETYLSALICYLIC ACID; ADIPOCYTOKINE; ANGIOTENSIN RECEPTOR ANTAGONIST; C REACTIVE PROTEIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FIBRIC ACID DERIVATIVE; GLITAZONE DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN RECEPTOR; LIPID; METFORMIN;

EID: 33749129189     PISSN: 03698114     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.patbio.2006.07.002     Document Type: Article
Times cited : (116)

References (124)
  • 1
    • 0024160877 scopus 로고
    • Banting lecture 1988. Role of insulin resistance in human disease
    • Reaven G.M. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 37 (1988) 1595-1607
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 2
    • 0000939795 scopus 로고
    • Studien ueber das Hypetonie-Hyperglykemia-Hyperurikemiasyndrom
    • Kylin E. Studien ueber das Hypetonie-Hyperglykemia-Hyperurikemiasyndrom. Zentralblatt fuer Inere Medizin. 44 (1923) 105-127
    • (1923) Zentralblatt fuer Inere Medizin. , vol.44 , pp. 105-127
    • Kylin, E.1
  • 3
    • 31744447164 scopus 로고    scopus 로고
    • How to best define the metabolic syndrome
    • Magliano D.J., Shaw J.E., and Zimmet P.Z. How to best define the metabolic syndrome. Ann. Med. 38 (2006) 34-41
    • (2006) Ann. Med. , vol.38 , pp. 34-41
    • Magliano, D.J.1    Shaw, J.E.2    Zimmet, P.Z.3
  • 4
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • Zimmet P., Alberti K.G.M.M., and Shaw J. Global and societal implications of the diabetes epidemic. Nature 414 (2001) 782-787
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.M.M.2    Shaw, J.3
  • 6
    • 0035897696 scopus 로고    scopus 로고
    • Evaluation, and treatment of high blood cholesterol in adults. executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
    • Expert Panel on Detection
    • Expert Panel on Detection. Evaluation, and treatment of high blood cholesterol in adults. executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA 285 (2001) 2486-2497
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 7
    • 33749136459 scopus 로고    scopus 로고
    • International Diabetes Federation. The IDF consensus worldwide definition of the metabolic syndrome. Brussels, Belgium: International Diabetes Federation; 2004. Available at: http://www.idf.org/webdata/docs/metabolic_syndrome_definifiton.pdf. Accessed June 15, 2005.
  • 8
    • 25144459980 scopus 로고    scopus 로고
    • for the IDF Epidemiology Task Force Consensus Group
    • Alberti K.G.M.M., Zimmet P., Shaw J., and for the IDF Epidemiology Task Force Consensus Group. Lancet 366 (2005) 1059-1062
    • (2005) Lancet , vol.366 , pp. 1059-1062
    • Alberti, K.G.M.M.1    Zimmet, P.2    Shaw, J.3
  • 9
    • 3242795814 scopus 로고    scopus 로고
    • Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome
    • Carr D.B., Utzschneider K.M., Hull R.L., Kodama K., Retzlaff B.M., Brunzell J.D., et al. Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome. Diabetes 53 (2004) 2087-2094
    • (2004) Diabetes , vol.53 , pp. 2087-2094
    • Carr, D.B.1    Utzschneider, K.M.2    Hull, R.L.3    Kodama, K.4    Retzlaff, B.M.5    Brunzell, J.D.6
  • 10
    • 13244267196 scopus 로고    scopus 로고
    • Metabolic syndrome and insulin resistance in the TROPHY sub-study: contrasting views in patients with high-normal blood pressure
    • TROPHY Sub-study Investigative Team
    • Egan B.M., Papademetriou V., Wofford M., Calhoun D., Fernandes J., Riehle J.E., et al., TROPHY Sub-study Investigative Team. Metabolic syndrome and insulin resistance in the TROPHY sub-study: contrasting views in patients with high-normal blood pressure. Am. J. Hypertens. 18 (2005) 3-12
    • (2005) Am. J. Hypertens. , vol.18 , pp. 3-12
    • Egan, B.M.1    Papademetriou, V.2    Wofford, M.3    Calhoun, D.4    Fernandes, J.5    Riehle, J.E.6
  • 11
    • 0037882913 scopus 로고    scopus 로고
    • Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease in nondiabetic American Indians: the Strong Heart Study
    • Strong Heart Study
    • Resnick H.E., Jones K., Ruotolo G., Jain A.K., Henderson J., Lu W., et al., Strong Heart Study. Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease in nondiabetic American Indians: the Strong Heart Study. Diabetes Care 26 (2003) 861-867
    • (2003) Diabetes Care , vol.26 , pp. 861-867
    • Resnick, H.E.1    Jones, K.2    Ruotolo, G.3    Jain, A.K.4    Henderson, J.5    Lu, W.6
  • 12
    • 0347853481 scopus 로고    scopus 로고
    • American College of Endocrinology Task Force on the insulin resistance syndrome. American College of Endocrinology position statement on the insulin resistance syndrome
    • American College of Endocrinology Task Force on the insulin resistance syndrome. American College of Endocrinology position statement on the insulin resistance syndrome. Endocr. Pract. 9 (2003) 236-252
    • (2003) Endocr. Pract. , vol.9 , pp. 236-252
  • 13
    • 1842485893 scopus 로고    scopus 로고
    • Critical evaluation of adult treatment panel III criteria in identifying insulin resistance with dyslipidemia
    • Liao Y., Kwon S., Shaughnessy S., Wallace P., Hutto A., Jenkins A.J., et al. Critical evaluation of adult treatment panel III criteria in identifying insulin resistance with dyslipidemia. Diabetes Care 27 (2004) 978-983
    • (2004) Diabetes Care , vol.27 , pp. 978-983
    • Liao, Y.1    Kwon, S.2    Shaughnessy, S.3    Wallace, P.4    Hutto, A.5    Jenkins, A.J.6
  • 14
    • 0034636818 scopus 로고    scopus 로고
    • Hypertriglyceridemic waist: a marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men?
    • Lemieux I., Pascot A., Couillard C., Lamarche B., Tchernof A., Almeras N., et al. Hypertriglyceridemic waist: a marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men?. Circulation 102 (2000) 179-184
    • (2000) Circulation , vol.102 , pp. 179-184
    • Lemieux, I.1    Pascot, A.2    Couillard, C.3    Lamarche, B.4    Tchernof, A.5    Almeras, N.6
  • 15
    • 23044447258 scopus 로고    scopus 로고
    • Point: the metabolic syndrome still lives
    • Grundy S.M. Point: the metabolic syndrome still lives. Clin. Chem. 51 (2005) 1352-1354
    • (2005) Clin. Chem. , vol.51 , pp. 1352-1354
    • Grundy, S.M.1
  • 16
    • 31744432315 scopus 로고    scopus 로고
    • The metabolic syndrome and cardiovascular disease
    • Bonora E. The metabolic syndrome and cardiovascular disease. Ann. Med. 38 (2006) 64-80
    • (2006) Ann. Med. , vol.38 , pp. 64-80
    • Bonora, E.1
  • 17
    • 31744438932 scopus 로고    scopus 로고
    • Metabolic syndrome: to be or not to be?
    • Laakso M., and Kovanen P.T. Metabolic syndrome: to be or not to be?. Ann. Med. 38 (2006) 32-33
    • (2006) Ann. Med. , vol.38 , pp. 32-33
    • Laakso, M.1    Kovanen, P.T.2
  • 18
    • 0027169321 scopus 로고
    • Transmembrane glucose transport in skeletal muscle of patients with non-insulin-dependent diabetes
    • Bonadonna R.C., Del Prato S., Saccomani M.P., Bonora E., Gulli G., Ferrannini E., et al. Transmembrane glucose transport in skeletal muscle of patients with non-insulin-dependent diabetes. J. Clin. Invest. 92 (1993) 486-494
    • (1993) J. Clin. Invest. , vol.92 , pp. 486-494
    • Bonadonna, R.C.1    Del Prato, S.2    Saccomani, M.P.3    Bonora, E.4    Gulli, G.5    Ferrannini, E.6
  • 19
    • 0033890616 scopus 로고    scopus 로고
    • Influence of obesity and type 2 diabetes on gluconeogenesis and glucose output in humans: a quantitative study
    • Gastaldelli A., Baldi S., Pettiti M., Toschi E., Camastra S., Natali A., et al. Influence of obesity and type 2 diabetes on gluconeogenesis and glucose output in humans: a quantitative study. Diabetes 49 (2000) 1367-1373
    • (2000) Diabetes , vol.49 , pp. 1367-1373
    • Gastaldelli, A.1    Baldi, S.2    Pettiti, M.3    Toschi, E.4    Camastra, S.5    Natali, A.6
  • 20
    • 24144493627 scopus 로고    scopus 로고
    • Increased fat mass compensates for insulin resistance in abdominal obesity and type 2 diabetes: a positron-emitting tomography study
    • Virtanen K.A., Iozzo P., Hallsten K., Huupponen R., Parkkola R., Janatuinen T., et al. Increased fat mass compensates for insulin resistance in abdominal obesity and type 2 diabetes: a positron-emitting tomography study. Diabetes 54 (2005) 2720-2726
    • (2005) Diabetes , vol.54 , pp. 2720-2726
    • Virtanen, K.A.1    Iozzo, P.2    Hallsten, K.3    Huupponen, R.4    Parkkola, R.5    Janatuinen, T.6
  • 21
    • 0028147131 scopus 로고
    • Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man
    • Del Prato S., Leonetti F., Simonson D.C., Sheehan P., Matsuda M., and DeFronzo R.A. Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man. Diabetologia 37 (1994) 1025-1035
    • (1994) Diabetologia , vol.37 , pp. 1025-1035
    • Del Prato, S.1    Leonetti, F.2    Simonson, D.C.3    Sheehan, P.4    Matsuda, M.5    DeFronzo, R.A.6
  • 22
    • 0024587721 scopus 로고
    • Biology of regional body fat distribution: relationship to non-insulin-dependent diabetes mellitus
    • Kissebah A.H., and Peiris A.N. Biology of regional body fat distribution: relationship to non-insulin-dependent diabetes mellitus. Biabetes Metab Rev. 5 (1989) 83-109
    • (1989) Biabetes Metab Rev. , vol.5 , pp. 83-109
    • Kissebah, A.H.1    Peiris, A.N.2
  • 23
    • 0023189066 scopus 로고
    • Relationships between plasma-free fatty acid concentration, endogenous glucose production, and fasting hyperglycemia in normal and non-insulin-dependent diabetic individuals
    • Golay A., Swislocki A.L., Chen Y.D., and Reaven G.M. Relationships between plasma-free fatty acid concentration, endogenous glucose production, and fasting hyperglycemia in normal and non-insulin-dependent diabetic individuals. Metabolism 36 (1987) 692-696
    • (1987) Metabolism , vol.36 , pp. 692-696
    • Golay, A.1    Swislocki, A.L.2    Chen, Y.D.3    Reaven, G.M.4
  • 25
    • 0025963777 scopus 로고
    • The role of free fatty acid metabolism in the pathogenesis of insulin resistance in obesity and noninsulin-dependent diabetes mellitus
    • Groop L.C., Saloranta C., Shank M., Bonadonna R.C., Ferrannini E., and DeFronzo R.A. The role of free fatty acid metabolism in the pathogenesis of insulin resistance in obesity and noninsulin-dependent diabetes mellitus. J. Clin. Endocrinol. Metab. 72 (1991) 96-107
    • (1991) J. Clin. Endocrinol. Metab. , vol.72 , pp. 96-107
    • Groop, L.C.1    Saloranta, C.2    Shank, M.3    Bonadonna, R.C.4    Ferrannini, E.5    DeFronzo, R.A.6
  • 26
    • 18644370344 scopus 로고    scopus 로고
    • Type 2 diabetes as a lipid disorder
    • Taskinen M.R. Type 2 diabetes as a lipid disorder. Curr. Mol. Med. 5 (2005) 297-308
    • (2005) Curr. Mol. Med. , vol.5 , pp. 297-308
    • Taskinen, M.R.1
  • 27
    • 0037109169 scopus 로고    scopus 로고
    • New perspective on atherogenesis: role of abnormal triglyceride-rich lipoprotein metabolism
    • Ginsberg H.N. New perspective on atherogenesis: role of abnormal triglyceride-rich lipoprotein metabolism. Circulation 106 (2002) 2137-2142
    • (2002) Circulation , vol.106 , pp. 2137-2142
    • Ginsberg, H.N.1
  • 28
    • 0035985081 scopus 로고    scopus 로고
    • Vascular function, insulin resistance and fatty acids
    • Steinberg H.O., and Baron A.D. Vascular function, insulin resistance and fatty acids. Diabeteologia 45 (2002) 623-634
    • (2002) Diabeteologia , vol.45 , pp. 623-634
    • Steinberg, H.O.1    Baron, A.D.2
  • 29
    • 0030680265 scopus 로고    scopus 로고
    • Insulin resistance, hyperinsulinemia, and blood pressure: role of age and obesity. European Group for the Study of Insulin Resistance (EGIR)
    • Ferrannini E., Natali A., Capaldo B., Lehtovirta M., Jacob S., and Yki-Jarvinen H. Insulin resistance, hyperinsulinemia, and blood pressure: role of age and obesity. European Group for the Study of Insulin Resistance (EGIR). Hypertension 30 (1997) 1144-1149
    • (1997) Hypertension , vol.30 , pp. 1144-1149
    • Ferrannini, E.1    Natali, A.2    Capaldo, B.3    Lehtovirta, M.4    Jacob, S.5    Yki-Jarvinen, H.6
  • 30
    • 0036020513 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells
    • Montagnani M., Ravichandran L.V., Chen H., Esposito D.L., and Quon M.J. Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells. Mol. Endocrinol. 16 (2002) 1931-1942
    • (2002) Mol. Endocrinol. , vol.16 , pp. 1931-1942
    • Montagnani, M.1    Ravichandran, L.V.2    Chen, H.3    Esposito, D.L.4    Quon, M.J.5
  • 31
    • 31744431904 scopus 로고    scopus 로고
    • Is insulin resistance the cause of the metabolic syndrome?
    • Ferrannini E. Is insulin resistance the cause of the metabolic syndrome?. Ann. Med. 38 (2006) 41-42
    • (2006) Ann. Med. , vol.38 , pp. 41-42
    • Ferrannini, E.1
  • 33
    • 0033849777 scopus 로고    scopus 로고
    • Obesity and insulin resistance
    • Kahn B.B., and Flier J.S. Obesity and insulin resistance. J. Clin. Invest. 106 (2000) 473-481
    • (2000) J. Clin. Invest. , vol.106 , pp. 473-481
    • Kahn, B.B.1    Flier, J.S.2
  • 34
    • 15044366018 scopus 로고    scopus 로고
    • Adipose tissue as an active endocrine organ: recent advances
    • Gimeno R.E., and Klaman L.D. Adipose tissue as an active endocrine organ: recent advances. Curr. Opin. Pharmacol. 5 (2005) 122-128
    • (2005) Curr. Opin. Pharmacol. , vol.5 , pp. 122-128
    • Gimeno, R.E.1    Klaman, L.D.2
  • 35
    • 29244465117 scopus 로고    scopus 로고
    • Fat as an endocrine organ: relationship to the metabolic syndrome
    • Hutley L., and Prins J.B. Fat as an endocrine organ: relationship to the metabolic syndrome. Am. J. Med. Sci. 330 (2005) 280-289
    • (2005) Am. J. Med. Sci. , vol.330 , pp. 280-289
    • Hutley, L.1    Prins, J.B.2
  • 36
    • 31744443753 scopus 로고    scopus 로고
    • Is visceral obesity the cause of the metabolic syndrome?
    • Després J.P. Is visceral obesity the cause of the metabolic syndrome?. Ann. Med. 38 (2006) 52-63
    • (2006) Ann. Med. , vol.38 , pp. 52-63
    • Després, J.P.1
  • 37
    • 0024564466 scopus 로고
    • Role of deep abdominal fat in the association between regional adipose tissue distribution and glucose tolerance in obese women
    • Despres J.P., Nadeau A., Tremblay A., Ferland M., Moorjani S., Lupien P.J., et al. Role of deep abdominal fat in the association between regional adipose tissue distribution and glucose tolerance in obese women. Diabetes 38 (1989) 304-309
    • (1989) Diabetes , vol.38 , pp. 304-309
    • Despres, J.P.1    Nadeau, A.2    Tremblay, A.3    Ferland, M.4    Moorjani, S.5    Lupien, P.J.6
  • 38
    • 0038305833 scopus 로고    scopus 로고
    • Obesity, regional fat distribution, and syndrome X in obese black versus white adolescents: race differential in diabetogenic and atherogenic risk factors
    • Bacha F., Saad R., Gungor N., Janosky J., and Arslanian S.A. Obesity, regional fat distribution, and syndrome X in obese black versus white adolescents: race differential in diabetogenic and atherogenic risk factors. J. Clin. Endocrinol. Metab. 88 (2003) 2534-2540
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 2534-2540
    • Bacha, F.1    Saad, R.2    Gungor, N.3    Janosky, J.4    Arslanian, S.A.5
  • 39
    • 33644674430 scopus 로고    scopus 로고
    • Pathophysiologic, diagnostic, and therapeutic aspects of the metabolic syndrome
    • Giles T.D., and Sander G.E. Pathophysiologic, diagnostic, and therapeutic aspects of the metabolic syndrome. J. Clin. Hypertens. 7 (2005) 669-678
    • (2005) J. Clin. Hypertens. , vol.7 , pp. 669-678
    • Giles, T.D.1    Sander, G.E.2
  • 40
    • 0002861937 scopus 로고    scopus 로고
    • Free fatty acids do they play a central role in type 2 diabetes?
    • Arner P. Free fatty acids do they play a central role in type 2 diabetes?. Diabetes Obes. Metab. Supl 1 (2001) S11-S19
    • (2001) Diabetes Obes. Metab. , Issue.Supl 1
    • Arner, P.1
  • 41
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
    • Hotamisligil G.S., Arner P., Caro J.F., Atkinson R.L., and Spiegelman B.M. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J. Clin. Invest. 95 (1995) 2409-2415
    • (1995) J. Clin. Invest. , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3    Atkinson, R.L.4    Spiegelman, B.M.5
  • 42
    • 0036010030 scopus 로고    scopus 로고
    • Effects of TNF-alpha on glucose metabolism and lipolysis in adipose tissue and isolated fat-cell preparations
    • Porter M.H., Cutchins A., Fine J.B., Bai Y., and DiGirolamo M. Effects of TNF-alpha on glucose metabolism and lipolysis in adipose tissue and isolated fat-cell preparations. J. Lab. Clin. Med. 139 (2002) 140-146
    • (2002) J. Lab. Clin. Med. , vol.139 , pp. 140-146
    • Porter, M.H.1    Cutchins, A.2    Fine, J.B.3    Bai, Y.4    DiGirolamo, M.5
  • 43
    • 2942698938 scopus 로고    scopus 로고
    • A novel pathway to the manifestations of metabolic syndrome
    • Sonnenberg G.E., Krakower G.R., and Kissebah A.H. A novel pathway to the manifestations of metabolic syndrome. Obes. Res. 12 (2004) 180-186
    • (2004) Obes. Res. , vol.12 , pp. 180-186
    • Sonnenberg, G.E.1    Krakower, G.R.2    Kissebah, A.H.3
  • 44
    • 0037020170 scopus 로고    scopus 로고
    • Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis
    • Matsuda M., Shimomura I., Sata M., Arita Y., Nishida M., Maeda N., et al. Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis. J. Biol. Chem. 277 (2002) 37487-37491
    • (2002) J. Biol. Chem. , vol.277 , pp. 37487-37491
    • Matsuda, M.1    Shimomura, I.2    Sata, M.3    Arita, Y.4    Nishida, M.5    Maeda, N.6
  • 45
    • 0036750241 scopus 로고    scopus 로고
    • Adiponectin-its role in metabolism and beyond
    • Stefan N., and Stumvoll M. Adiponectin-its role in metabolism and beyond. Horm. Metab. Res. 34 (2002) 469-474
    • (2002) Horm. Metab. Res. , vol.34 , pp. 469-474
    • Stefan, N.1    Stumvoll, M.2
  • 46
    • 0036511213 scopus 로고    scopus 로고
    • ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism
    • Berg A.H., Combs T.P., and Scherer P.E. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol. Metab. 13 (2002) 84-89
    • (2002) Trends Endocrinol. Metab. , vol.13 , pp. 84-89
    • Berg, A.H.1    Combs, T.P.2    Scherer, P.E.3
  • 47
    • 4544241860 scopus 로고    scopus 로고
    • Adiponectin, the missing link in insulin resistance and obesity
    • Gil-Campos M., Canete R.R., and Gil A. Adiponectin, the missing link in insulin resistance and obesity. Clin. Nutr. 23 (2004) 963-974
    • (2004) Clin. Nutr. , vol.23 , pp. 963-974
    • Gil-Campos, M.1    Canete, R.R.2    Gil, A.3
  • 50
    • 0038577223 scopus 로고    scopus 로고
    • Minireview: adiposity, inflammation, and atherogenesis
    • Lyon C.J., Law R.E., and Hsueh W.A. Minireview: adiposity, inflammation, and atherogenesis. Endocrinology 144 (2003) 2195-2200
    • (2003) Endocrinology , vol.144 , pp. 2195-2200
    • Lyon, C.J.1    Law, R.E.2    Hsueh, W.A.3
  • 51
    • 0030434655 scopus 로고    scopus 로고
    • Leptin and OB-R: body weight regulation by a cytokine receptor
    • White D.W., and Tartaglia L.A. Leptin and OB-R: body weight regulation by a cytokine receptor. Cytokine Growth Factor Rev. 7 (1996) 303-309
    • (1996) Cytokine Growth Factor Rev. , vol.7 , pp. 303-309
    • White, D.W.1    Tartaglia, L.A.2
  • 53
    • 3142510687 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis and diabetes mellitus
    • Plutzky J. Inflammation in atherosclerosis and diabetes mellitus. Rev Endocrinol. Metab. Disord. 5 (2004) 255-259
    • (2004) Rev Endocrinol. Metab. Disord. , vol.5 , pp. 255-259
    • Plutzky, J.1
  • 54
    • 27744463859 scopus 로고    scopus 로고
    • Central obesity as a major determinant of increased high-sensitivity C-reactive protein in metabolic syndrome
    • Santos A.C., Lopes C., Guimarâes J.T., and Barros H. Central obesity as a major determinant of increased high-sensitivity C-reactive protein in metabolic syndrome. Int. J. Obes. 29 (2005) 1452-1456
    • (2005) Int. J. Obes. , vol.29 , pp. 1452-1456
    • Santos, A.C.1    Lopes, C.2    Guimarâes, J.T.3    Barros, H.4
  • 55
    • 0037469255 scopus 로고    scopus 로고
    • C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14 719 initially healthy American women
    • Ridker P., Buring J., Cook N., and Rifai N. C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14 719 initially healthy American women. Circulation 107 (2003) 391-397
    • (2003) Circulation , vol.107 , pp. 391-397
    • Ridker, P.1    Buring, J.2    Cook, N.3    Rifai, N.4
  • 56
    • 0032943709 scopus 로고    scopus 로고
    • C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?
    • Yudkin J.S., Stehouwer C.D., Emeis J.J., and Coppack S.W. C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?. Arterioscler. Thromb. Vasc. Biol. 19 (1999) 972-978
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 972-978
    • Yudkin, J.S.1    Stehouwer, C.D.2    Emeis, J.J.3    Coppack, S.W.4
  • 57
    • 0032790922 scopus 로고    scopus 로고
    • Associations of C-reactive protein with measures of obesity, insulin resistance, and subclinical atherosclerosis in healthy, middle-aged women
    • Hak A.E., Stehouwer C.D., Bots M.L., Polderman K.H., Schalkwijk C.G., Westendorp I.C., et al. Associations of C-reactive protein with measures of obesity, insulin resistance, and subclinical atherosclerosis in healthy, middle-aged women. Arterioscler. Thromb. Vasc. Biol. 19 (1999) 1986-1991
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 1986-1991
    • Hak, A.E.1    Stehouwer, C.D.2    Bots, M.L.3    Polderman, K.H.4    Schalkwijk, C.G.5    Westendorp, I.C.6
  • 58
    • 0034604248 scopus 로고    scopus 로고
    • Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS)
    • Festa A., D'Agostino Jr. R., Howard G., Mykkanen L., Tracy R.P., and Haffner S.M. Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS). Circulation 102 (2000) 42-47
    • (2000) Circulation , vol.102 , pp. 42-47
    • Festa, A.1    D'Agostino Jr., R.2    Howard, G.3    Mykkanen, L.4    Tracy, R.P.5    Haffner, S.M.6
  • 59
    • 0030731621 scopus 로고    scopus 로고
    • NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X
    • Pickup J.C., Mattock M.B., Chusney G.D., and Burt D. NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X. Diabetologia 40 (1997) 1286-1292
    • (1997) Diabetologia , vol.40 , pp. 1286-1292
    • Pickup, J.C.1    Mattock, M.B.2    Chusney, G.D.3    Burt, D.4
  • 60
    • 33645319007 scopus 로고    scopus 로고
    • Inflammatory markers and type 2 diabetes
    • Pickup J.C. Inflammatory markers and type 2 diabetes. Diabetes Tech. Therap. 8 (2006) 1-6
    • (2006) Diabetes Tech. Therap. , vol.8 , pp. 1-6
    • Pickup, J.C.1
  • 61
    • 5644231992 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
    • Ozcan U., Cao Q., Tilmaz E., Lee A.H., Iwakoshi N., Ozdelen E., et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306 (2004) 457-461
    • (2004) Science , vol.306 , pp. 457-461
    • Ozcan, U.1    Cao, Q.2    Tilmaz, E.3    Lee, A.H.4    Iwakoshi, N.5    Ozdelen, E.6
  • 62
    • 33644670203 scopus 로고    scopus 로고
    • Plasma fatty acid composition is associated with the metabolic syndrome and low-grade inflammation in overweight adolescents
    • Klein-Platat C., Drai J., Oujaa M., Schlienger J.L., and Simon C. Plasma fatty acid composition is associated with the metabolic syndrome and low-grade inflammation in overweight adolescents. Am. J. Clin. Nutr. 82 (2005) 1178-1184
    • (2005) Am. J. Clin. Nutr. , vol.82 , pp. 1178-1184
    • Klein-Platat, C.1    Drai, J.2    Oujaa, M.3    Schlienger, J.L.4    Simon, C.5
  • 63
    • 21344460247 scopus 로고    scopus 로고
    • An immune origin of type 2 diabetes?
    • Kolb H., and Mandrup-Poulsen T. An immune origin of type 2 diabetes?. Diabetologia 48 (2005) 1038-1050
    • (2005) Diabetologia , vol.48 , pp. 1038-1050
    • Kolb, H.1    Mandrup-Poulsen, T.2
  • 65
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a critical role in the development of obesity related insulin resistance
    • Xu H., Barnes G.T., and Yang Q. Chronic inflammation in fat plays a critical role in the development of obesity related insulin resistance. J Clin Invest 112 (2003) 1821-1830
    • (2003) J Clin Invest , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3
  • 66
    • 33645452759 scopus 로고    scopus 로고
    • The dysregulated adipose tissue: a connecting link between insulin resistance, type 2 diabetes mellitus and atherosclerosis
    • Murdolo G., and Smith U. The dysregulated adipose tissue: a connecting link between insulin resistance, type 2 diabetes mellitus and atherosclerosis. Nutr. Metab. Cardiovasc. Dis. 16 (2006) 535-538
    • (2006) Nutr. Metab. Cardiovasc. Dis. , vol.16 , pp. 535-538
    • Murdolo, G.1    Smith, U.2
  • 68
    • 0034959752 scopus 로고    scopus 로고
    • Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis
    • Makowski L., Boord J.B., Maeda K., Babaev V.R., Uysal K.T., Morgan M.A., et al. Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis. Nat. Med. 7 (2001) 699-705
    • (2001) Nat. Med. , vol.7 , pp. 699-705
    • Makowski, L.1    Boord, J.B.2    Maeda, K.3    Babaev, V.R.4    Uysal, K.T.5    Morgan, M.A.6
  • 69
    • 18244370762 scopus 로고    scopus 로고
    • Inflammation, stress, and diabetes
    • Wellen K.E., and Hotamisligil G.S. Inflammation, stress, and diabetes. J. Clin. Invest. 115 (2005) 1111-1119
    • (2005) J. Clin. Invest. , vol.115 , pp. 1111-1119
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 70
    • 28244466397 scopus 로고    scopus 로고
    • Inflammatory markers and the metabolic syndrome
    • Koh K.K., Hwan Han S., and Quon M.J. Inflammatory markers and the metabolic syndrome. J. Am. Coll. Cardiol. 46 (2005) 1978-1985
    • (2005) J. Am. Coll. Cardiol. , vol.46 , pp. 1978-1985
    • Koh, K.K.1    Hwan Han, S.2    Quon, M.J.3
  • 72
    • 10744233017 scopus 로고    scopus 로고
    • Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome
    • Troseid M., Lappegard K.T., Claudi T., Damas J.K., Morkrid L., Brendberg R., et al. Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome. Eur. Heart J. 25 (2004) 349-355
    • (2004) Eur. Heart J. , vol.25 , pp. 349-355
    • Troseid, M.1    Lappegard, K.T.2    Claudi, T.3    Damas, J.K.4    Morkrid, L.5    Brendberg, R.6
  • 73
    • 0024489402 scopus 로고
    • The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells
    • Endres S., Ghorbani R., Kelley V.E., Georgilis K., Lonnemann G., van der Meer J.W., et al. The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. N. Engl. J. Med. 320 (1989) 265-271
    • (1989) N. Engl. J. Med. , vol.320 , pp. 265-271
    • Endres, S.1    Ghorbani, R.2    Kelley, V.E.3    Georgilis, K.4    Lonnemann, G.5    van der Meer, J.W.6
  • 74
    • 33645299587 scopus 로고    scopus 로고
    • Nutritional influences on inflammation and type 2 diabetes risk
    • Browning L., and Jebb S.A. Nutritional influences on inflammation and type 2 diabetes risk. Diabetes Technol. Ther. 8 (2006) 45-54
    • (2006) Diabetes Technol. Ther. , vol.8 , pp. 45-54
    • Browning, L.1    Jebb, S.A.2
  • 75
    • 33646543284 scopus 로고    scopus 로고
    • The modulation of inflammatory gene expression by lipids: mediation through toll-like receptors
    • Lee J.Y., and Hwang D.H. The modulation of inflammatory gene expression by lipids: mediation through toll-like receptors. Mol. Cells 21 (2006) 174-185
    • (2006) Mol. Cells , vol.21 , pp. 174-185
    • Lee, J.Y.1    Hwang, D.H.2
  • 76
    • 13244252424 scopus 로고    scopus 로고
    • Mechanisms regulating phosphoinositide 3-kinase signalling in insulin-sensitive tissues
    • Shepherd P.R. Mechanisms regulating phosphoinositide 3-kinase signalling in insulin-sensitive tissues. Acta Physiol. Scand. 183 (2005) 3-12
    • (2005) Acta Physiol. Scand. , vol.183 , pp. 3-12
    • Shepherd, P.R.1
  • 77
    • 0030748457 scopus 로고    scopus 로고
    • Yhe insulin signalling system and the IRS proteins
    • White M.F. Yhe insulin signalling system and the IRS proteins. Diabetologia 40 Suppl 2 (1997) S2-S17
    • (1997) Diabetologia , vol.40 , Issue.SUPPL. 2
    • White, M.F.1
  • 79
    • 25844456730 scopus 로고    scopus 로고
    • Tumor necrosis factor-x induces skeletal muscle insulin resistance in healthy human subjects via inhibition of akt substrate 160 phosphorylation
    • Plomgaard P., Bouzakri K., Krogh-Madsen R., Mittendorfer B., Zierath J.R., and Pedersen B.K. Tumor necrosis factor-x induces skeletal muscle insulin resistance in healthy human subjects via inhibition of akt substrate 160 phosphorylation. Diabetes 54 (2005) 2939-2945
    • (2005) Diabetes , vol.54 , pp. 2939-2945
    • Plomgaard, P.1    Bouzakri, K.2    Krogh-Madsen, R.3    Mittendorfer, B.4    Zierath, J.R.5    Pedersen, B.K.6
  • 80
    • 2642563899 scopus 로고    scopus 로고
    • Regulation of insulin sensitivity by adipose tissue-derived hormones and inflammatory cytokines
    • Ruan H., and Lodish H.F. Regulation of insulin sensitivity by adipose tissue-derived hormones and inflammatory cytokines. Curr. Opin. Lipidol. 15 (2004) 297-302
    • (2004) Curr. Opin. Lipidol. , vol.15 , pp. 297-302
    • Ruan, H.1    Lodish, H.F.2
  • 81
    • 0041374029 scopus 로고    scopus 로고
    • Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-alpha
    • Ruan H., and Lodish H.F. Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-alpha. Cytokine Growth Factor Rev. 14 (2003) 447-455
    • (2003) Cytokine Growth Factor Rev. , vol.14 , pp. 447-455
    • Ruan, H.1    Lodish, H.F.2
  • 82
    • 18144408371 scopus 로고    scopus 로고
    • Adipose tissue, adipokines, and inflammation
    • Fantuzzi G. Adipose tissue, adipokines, and inflammation. J. Allergy Clin. Immunol. 115 (2005) 911-919
    • (2005) J. Allergy Clin. Immunol. , vol.115 , pp. 911-919
    • Fantuzzi, G.1
  • 85
    • 18044393626 scopus 로고    scopus 로고
    • Insulin signal transduction in human skeletal muscle: identifying the defects in type II diabetes
    • Björnholm M., and Zierath J.R. Insulin signal transduction in human skeletal muscle: identifying the defects in type II diabetes. Biochem. Soc. Trans. 33 (2005) 354-361
    • (2005) Biochem. Soc. Trans. , vol.33 , pp. 354-361
    • Björnholm, M.1    Zierath, J.R.2
  • 86
    • 16844370268 scopus 로고    scopus 로고
    • Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway
    • Ueno M., Carvalheira J.B.C., Tambascia R.C., Bezerra R.M.N., Amaral M.E., Carneiro E.M., et al. Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway. Diabetologia 48 (2005) 506-518
    • (2005) Diabetologia , vol.48 , pp. 506-518
    • Ueno, M.1    Carvalheira, J.B.C.2    Tambascia, R.C.3    Bezerra, R.M.N.4    Amaral, M.E.5    Carneiro, E.M.6
  • 87
    • 8744259926 scopus 로고    scopus 로고
    • Uncoupling insulin signalling by serin/threonine phosphorylation: a molecular basis for insulin resistance
    • Zick Y. Uncoupling insulin signalling by serin/threonine phosphorylation: a molecular basis for insulin resistance. Biochem. Soc. Trans. 32 (2004) 812-816
    • (2004) Biochem. Soc. Trans. , vol.32 , pp. 812-816
    • Zick, Y.1
  • 88
    • 2942569351 scopus 로고    scopus 로고
    • Oxidative stress induces insulin resistance by activating the nuclear factor-kB pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase
    • Ogihara T., Asano T., Katagiri H., Sakoda H., Anai M., Shojima N., et al. Oxidative stress induces insulin resistance by activating the nuclear factor-kB pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase. Diabetologia 47 (2004) 794-805
    • (2004) Diabetologia , vol.47 , pp. 794-805
    • Ogihara, T.1    Asano, T.2    Katagiri, H.3    Sakoda, H.4    Anai, M.5    Shojima, N.6
  • 92
    • 33645312390 scopus 로고    scopus 로고
    • The epidemiology of low-grade chronic systemic inflammation and type 2 diabetes
    • Duncan B.B., and Schmidt M.I. The epidemiology of low-grade chronic systemic inflammation and type 2 diabetes. Diabetes Technolog & Therapeutics 8 (2006) 7-17
    • (2006) Diabetes Technolog & Therapeutics , vol.8 , pp. 7-17
    • Duncan, B.B.1    Schmidt, M.I.2
  • 94
    • 31344447948 scopus 로고    scopus 로고
    • The metabolic syndrome: inflammation, diabetes mellitus, and cardiovascular disease
    • Haffner S. The metabolic syndrome: inflammation, diabetes mellitus, and cardiovascular disease. Am. J. Cardiol. Suppl 3 (2006) 3A-11A
    • (2006) Am. J. Cardiol. , Issue.SUPPL. 3
    • Haffner, S.1
  • 95
    • 0346250165 scopus 로고    scopus 로고
    • Cellular mechanism of insulin resistance: potential links with inflammation
    • Perseghin G., Petersen K., and Shulman G.I. Cellular mechanism of insulin resistance: potential links with inflammation. Int. J. Obes. Relat. Metab. Disord. 27 Suppl 3 (2003) S6-S11
    • (2003) Int. J. Obes. Relat. Metab. Disord. , vol.27 , Issue.SUPPL. 3
    • Perseghin, G.1    Petersen, K.2    Shulman, G.I.3
  • 96
    • 0037853260 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes
    • Senn J.J., Klover P.J., Nowak I.A., Zimmers T.A., Koniaris L.G., Furlanetto R.W., et al. Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes. J. Biol. Chem. 278 16 (2003) 13740-13746
    • (2003) J. Biol. Chem. , vol.278 , Issue.16 , pp. 13740-13746
    • Senn, J.J.1    Klover, P.J.2    Nowak, I.A.3    Zimmers, T.A.4    Koniaris, L.G.5    Furlanetto, R.W.6
  • 97
    • 0037407403 scopus 로고    scopus 로고
    • NCEP-defined metabolic syndrome, diabetes and prevalence of coronary heart disease among NHANES III participants age 50 years and older
    • Third National Health and Nutrition Examination Survey (NCEP)
    • Third National Health and Nutrition Examination Survey (NCEP). NCEP-defined metabolic syndrome, diabetes and prevalence of coronary heart disease among NHANES III participants age 50 years and older. Diabetes 52 (2003) 1210-1214
    • (2003) Diabetes , vol.52 , pp. 1210-1214
  • 98
    • 0037126526 scopus 로고    scopus 로고
    • Third report of the of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III) final report
    • Third report of the of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III) final report. Circulation 106 (2002) 3143-3421
    • (2002) Circulation , vol.106 , pp. 3143-3421
  • 99
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey
    • Ford E.S., Giles W.H., and Dietz W.H. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 287 (2002) 356-359
    • (2002) JAMA , vol.287 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3
  • 101
    • 1442282377 scopus 로고    scopus 로고
    • The metabolic syndrome and aging
    • Morley J.E. The metabolic syndrome and aging. J. Gerontol. 59A (2004) 139-142
    • (2004) J. Gerontol. , vol.59 A , pp. 139-142
    • Morley, J.E.1
  • 103
    • 29144442899 scopus 로고    scopus 로고
    • Linking age-related changes in skeletal muscle mass and composition with metabolism and disease
    • Janssen I., and Ross R. Linking age-related changes in skeletal muscle mass and composition with metabolism and disease. J. health Nutr. Aging 9 6 (2005) 408-419
    • (2005) J. health Nutr. Aging , vol.9 , Issue.6 , pp. 408-419
    • Janssen, I.1    Ross, R.2
  • 104
    • 0036727512 scopus 로고    scopus 로고
    • Measuring body fat distribution and content in humans
    • Goodpaster B.H. Measuring body fat distribution and content in humans. Curr. Opin. Clin. Nutr. Metab. Care 5 5 (2002) 481-487
    • (2002) Curr. Opin. Clin. Nutr. Metab. Care , vol.5 , Issue.5 , pp. 481-487
    • Goodpaster, B.H.1
  • 105
    • 19944392873 scopus 로고    scopus 로고
    • Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians
    • Franceschi C., Olivieri F., Marchegiani F., Cardelli M., Cavallone L., Capri M., et al. Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians. Mech. Ageing Dev. 126 2 (2005) 351-361
    • (2005) Mech. Ageing Dev. , vol.126 , Issue.2 , pp. 351-361
    • Franceschi, C.1    Olivieri, F.2    Marchegiani, F.3    Cardelli, M.4    Cavallone, L.5    Capri, M.6
  • 107
    • 27544492807 scopus 로고    scopus 로고
    • Control of aging and longevity by IGF-I signaling
    • Yang J., Anzo M., and Cohen P. Control of aging and longevity by IGF-I signaling. Exp Geront. 40 (2005) 867-872
    • (2005) Exp Geront. , vol.40 , pp. 867-872
    • Yang, J.1    Anzo, M.2    Cohen, P.3
  • 108
    • 12744277871 scopus 로고    scopus 로고
    • Evolutionary and mechanistic theories of aging
    • Hughes K.A., and Reynolds R.M. Evolutionary and mechanistic theories of aging. Annu. Rev. Entomol. 50 (2005) 421-445
    • (2005) Annu. Rev. Entomol. , vol.50 , pp. 421-445
    • Hughes, K.A.1    Reynolds, R.M.2
  • 109
    • 33644507693 scopus 로고    scopus 로고
    • Long lived Klotho mice: new insights into the roles of IGF-1 and insulin in aging
    • Bartke A. Long lived Klotho mice: new insights into the roles of IGF-1 and insulin in aging. Trends Endocrinol. Metab. 17 (2006) 33-35
    • (2006) Trends Endocrinol. Metab. , vol.17 , pp. 33-35
    • Bartke, A.1
  • 110
    • 11044228316 scopus 로고    scopus 로고
    • Do deficiencies in growth hormone and insulin like growth factor-1 (IGF-1) shorten or prolong longevity?
    • Laron Z. Do deficiencies in growth hormone and insulin like growth factor-1 (IGF-1) shorten or prolong longevity?. Mech. Ageing Dev. 126 (2005) 305-307
    • (2005) Mech. Ageing Dev. , vol.126 , pp. 305-307
    • Laron, Z.1
  • 111
    • 27544434895 scopus 로고    scopus 로고
    • The insulin/IGF-1 signalling in mammals and its relevance to human longevity
    • Rincon M., Rudin E., and Barzilai N. The insulin/IGF-1 signalling in mammals and its relevance to human longevity. Exp Geront. 40 (2005) 873-877
    • (2005) Exp Geront. , vol.40 , pp. 873-877
    • Rincon, M.1    Rudin, E.2    Barzilai, N.3
  • 112
    • 0142088521 scopus 로고    scopus 로고
    • Unique lipoprotein phenotype and genotype associated with exceptional longevity
    • Barzilai N., Atzmon G., Schechter C., Schaefer E.J., Cupples A.L., Lipton R., et al. Unique lipoprotein phenotype and genotype associated with exceptional longevity. JAMA 290 15 (2003) 2030-2040
    • (2003) JAMA , vol.290 , Issue.15 , pp. 2030-2040
    • Barzilai, N.1    Atzmon, G.2    Schechter, C.3    Schaefer, E.J.4    Cupples, A.L.5    Lipton, R.6
  • 113
    • 27644565161 scopus 로고    scopus 로고
    • Review article: the metabolic syndrome a chronic cardiovascular inflammatory condition
    • Zambon A., Pauletto P., and Crepaldi G. Review article: the metabolic syndrome a chronic cardiovascular inflammatory condition. Aliment. Pharmacol. Ther. 22 Suppl. 2 (2005) 20-23
    • (2005) Aliment. Pharmacol. Ther. , vol.22 , Issue.SUPPL. 2 , pp. 20-23
    • Zambon, A.1    Pauletto, P.2    Crepaldi, G.3
  • 114
    • 33749133044 scopus 로고    scopus 로고
    • Metabolic syndrome: a marker of patients at high cardiovascular risk
    • Lau D.C.W., Yan H., and Dhillon B. Metabolic syndrome: a marker of patients at high cardiovascular risk. Can. J. Cardiol. 22 (2006) 85B-90B
    • (2006) Can. J. Cardiol. , vol.22
    • Lau, D.C.W.1    Yan, H.2    Dhillon, B.3
  • 115
    • 33646150221 scopus 로고    scopus 로고
    • Metabolic syndrome and age-related dementia: endocrinological aspects of adaptation to aging
    • Hashizume K., Suzuki S., Hara M., Komatsu A., and Yamashita K. Metabolic syndrome and age-related dementia: endocrinological aspects of adaptation to aging. Mech. Ageing Dev. 127 (2006) 507-510
    • (2006) Mech. Ageing Dev. , vol.127 , pp. 507-510
    • Hashizume, K.1    Suzuki, S.2    Hara, M.3    Komatsu, A.4    Yamashita, K.5
  • 116
    • 28444459842 scopus 로고    scopus 로고
    • Insulin resistance syndrome and Alzheimer disease: age and obesity-related effects on memory, amyloid and inflammation
    • Craft S. Insulin resistance syndrome and Alzheimer disease: age and obesity-related effects on memory, amyloid and inflammation. Neurobiol. Aging 26 (2005) S65-S69
    • (2005) Neurobiol. Aging , vol.26
    • Craft, S.1
  • 117
    • 0035799806 scopus 로고    scopus 로고
    • Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
    • Finnish Diabetes Prevention Study Group.
    • Tuomilehto J., Lindstrom J., Eriksson J.G., Valle T.T., Hamalainen H., Ilanne-Parikka P., et al., Finnish Diabetes Prevention Study Group. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N. Engl. J. Med. 344 (2001) 1343-1350
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1343-1350
    • Tuomilehto, J.1    Lindstrom, J.2    Eriksson, J.G.3    Valle, T.T.4    Hamalainen, H.5    Ilanne-Parikka, P.6
  • 118
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Diebetes Prevention Program Research Group.
    • Knowler W.C., Barrett-Connor E., Fowler S.E., Hamman R.F., Lachin J.M., Walker E.A., et al., Diebetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N. Engl. J. Med. 346 (2002) 393-403
    • (2002) N. Engl. J. Med. , vol.346 , pp. 393-403
    • Knowler, W.C.1    Barrett-Connor, E.2    Fowler, S.E.3    Hamman, R.F.4    Lachin, J.M.5    Walker, E.A.6
  • 119
    • 33644779573 scopus 로고    scopus 로고
    • Insulin sensitizers may prevent metabolic inflammation
    • Colca J.R. Insulin sensitizers may prevent metabolic inflammation. Biochem. Pharmacol. 72 (2006) 125-131
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 125-131
    • Colca, J.R.1
  • 120
    • 26244444079 scopus 로고    scopus 로고
    • Inflammatory markers and the metabolic syndrome
    • Athyros V.G., Elisaf M., and Mikhalidis D.P. Inflammatory markers and the metabolic syndrome. Atherosclerosis 183 (2005) 187-188
    • (2005) Atherosclerosis , vol.183 , pp. 187-188
    • Athyros, V.G.1    Elisaf, M.2    Mikhalidis, D.P.3
  • 121
    • 23744441515 scopus 로고    scopus 로고
    • Insulin resistance and inflammation in the early phase of type 2 diabetes: potential for therapeutic intervention
    • Schernthaner G.H., and Schernthaner G. Insulin resistance and inflammation in the early phase of type 2 diabetes: potential for therapeutic intervention. Scand. J. Clin. Lab. Invest. 65 Suppl 240 (2005) 30-40
    • (2005) Scand. J. Clin. Lab. Invest. , vol.65 , Issue.SUPPL. 240 , pp. 30-40
    • Schernthaner, G.H.1    Schernthaner, G.2
  • 122
    • 24644473131 scopus 로고    scopus 로고
    • Insulin resistance, obesity and the metabolic syndrome. Is a there a therapeutic role for endothelin-1 antagonists?
    • Shaw S.G., and Boden J.P. Insulin resistance, obesity and the metabolic syndrome. Is a there a therapeutic role for endothelin-1 antagonists?. Current Vascular Pharmacology 3 (2005) 359-363
    • (2005) Current Vascular Pharmacology , vol.3 , pp. 359-363
    • Shaw, S.G.1    Boden, J.P.2
  • 123
    • 33748442637 scopus 로고    scopus 로고
    • The metabolic syndrome: evolving evidence that thiazolidinediones provide rational therapy
    • Wyne K.L. The metabolic syndrome: evolving evidence that thiazolidinediones provide rational therapy. Diabetes Obes. Metab. 8 4 (2006) 365-380
    • (2006) Diabetes Obes. Metab. , vol.8 , Issue.4 , pp. 365-380
    • Wyne, K.L.1
  • 124
    • 33745648548 scopus 로고    scopus 로고
    • Metabolic syndrome and hypertension: prevention and treatment
    • Bernardi R., Cosentino E.R., and Borghi C. Metabolic syndrome and hypertension: prevention and treatment. Minerva Med. 97 2 (2006) 123-141
    • (2006) Minerva Med. , vol.97 , Issue.2 , pp. 123-141
    • Bernardi, R.1    Cosentino, E.R.2    Borghi, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.