The immunological synapse: Models facing facts;La synapse immunologique: Des modèles aux réalités

Medecine/Sciences

Volumn 22, Issue 8-9, 2006, Pages 721-726

  Bismuth, Georges ^a   Trautmann, Alain ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXO;

CELL INTERACTION; CELL STRUCTURE; CLINICAL IMMUNOLOGY; DENDRITIC CELL; IMMOBILIZED CELL; IN VIVO STUDY; LIPID BILAYER; LYMPHOMA; REVIEW; SENSITIZATION; SYNAPSE; SYNAPTIC TRANSMISSION; T LYMPHOCYTE;

EID: 33748868283     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/20062289721     Document Type: Review

References (28)

1. Davis DM, Dustin ML. What is the importance of the immunological synapse? Trends Immunol 2004; 25: 323-7.
2. Monks CR, Freiberg BA, Kupfer H, et al. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 1998; 395: 82-6.
3. Grakoui A, Bromley SK, Sumen C, et al. The immunological synapse: a molecular machine controlling T cell activation. Science 1999; 285: 221-7.
4. Mempel TR, Henrickson SE, Von Andrian UH. T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 2004; 427: 154-9.
5. + T cell activation by dendritic cells in lymph nodes. J Exp Med 2004; 200: 847-56.
6. Miller MJ, Wei SH, Parker I, Cahalan MD. Two-photon imaging of lymphocyte motility arid antigen response in intact lymph node. Science 2002; 296: 1869-73.
7. + T cell priming by dendritic cells in intact lymph nodes. Nat Immunol 2003; 4: 579-85.
8. Stoll S, Delon J, Brotz TM, Germain RN. Dynamic imaging of T cell-dendritic cell interactions in lymph nodes. Science 2002; 296: 1873-6.
9. Lee KH, Holdorf AD, Dustin ML, et al. T cell receptor signaling precedes immunological synapse formation. Science 2002; 295: 1539-42.
10. Schamel WW, Arechaga I, Risueno RM, et al. Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response. J Exp Med 2005; 202: 493-503.
11. Randriamampita C, Boulla G, Revy P, et al. T cell adhesion lowers the threshold for antigen detection. Eur J Immunol 2003; 33: 1215-23.
12. Kaiser A, Donnadieu E, Abastado JP, et al. CC chemokine ligand 19 secreted by mature dendritic cells increases naive T cell scanning behavior and their response to rare cognate antigen. J Immunol 2005; 175: 2349-56.
13. Molon B, Gri G, Bettella M, et al. T cell costimulation by chemokine receptors. Nat Immunol 2005; 6: 465-71.
14. Trautmann A. Chemokines as immunotransmitters? Nat Immunol 2005; 6: 427-8.
15. Brossard C, Feuillet V, Schmitt A, et al. Multifocal structure of the T cell dendritic cell synapse. Eur J Immunol 2005; 35: 1741-53.
16. + T cells in the absence of exogenous antigen. J Immunol 2004; 173: 50-60.
17. Benvenuti F, Hugues S, Walmsley M, et al. Requirement of Rac1 and Rac2 expression by mature dendritic cells for T cell priming. Science 2004; 305: 1150-3.
18. Faure S, Salazar-Fontana LI, Semichon M, et al. ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation. Nat Immunol 2004; 5: 272-9.
19. Depoil D, Zaru R, Guiraud M, et al. Immunological synapses are versatile structures enabling selective T cell polarization. Immunity 2005; 22: 185-94.
20. Yokosuka T, Sakata-Sogawa K, Kobayashi W, et al. Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. Nat Immunol 2005; 6: 1253-62.
21. Campi G, Varma R, Dustin ML. Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J Exp Med 2005; 202: 1031-6.
22. Irvine DJ, Purbhoo MA, Krogsgaard M, Davis MM. Direct observation of ligand recognition by T cells. Nature 2002; 419: 845-9.
23. Lee KH, Dinner AR, Tu C, et al. The immunological synapse balances T cell receptor signaling and degradation. Science 2003; 302: 1218-22.
24. Harriague J, Bismuth G. Imaging antigen-induced PI3K activation in T cells. Nat Immunol 2002; 3: 1090-6.
25. Costello PS, Gallagher M, Cantrell DA. Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse. Nat Immunol 2002; 3: 1082-9.
26. Fabre S, Lang V, Harriague J, et al. Stable activation of phosphatidylinositol 3-kinase in the T cell immunological synapse stimulates Akt signaling to Fox01 nuclear exclusion and cell growth control. J Immunol 2005; 174: 4161-71.
27. Das V, Nal B, Dujeancourt A, et al. Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse; involvement of SNARE complexes. Immunity 2004; 20: 577-88.
28. Huppa JB, Gleimer M, Sumen C, Davis MM. Continuous T cell receptor signaling required for synapse maintenance and full effector potential. Nat Immunol 2003; 4: 749-55.