Interaction between HP1α and replication proteins in mammalian cells

Experimental Cell Research

Volumn 312, Issue 17, 2006, Pages 3349-3359

  Auth, Tanja ^a   Kunkel, Elisabeth ^b   Grummt, Friedrich ^b  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Centrosome; HP1 ; ORC; RNAi

Indexed keywords

CELL CYCLE PROTEIN 6; CELL PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; HETEROCHROMATIN PROTEIN 1; HETEROCHROMATIN PROTEIN 1 ALPHA; HYBRID PROTEIN; RNA; UNCLASSIFIED DRUG; CDC6 PROTEIN, MOUSE; CELL CYCLE PROTEIN; HETEROCHROMATIN SPECIFIC NONHISTONE CHROMOSOMAL PROTEIN HP 1; HETEROCHROMATIN-SPECIFIC NONHISTONE CHROMOSOMAL PROTEIN HP-1; NONHISTONE PROTEIN; NUCLEAR PROTEIN; ORIGIN RECOGNITION COMPLEX; SMALL INTERFERING RNA; TUBULIN;

ANIMAL CELL; ARTICLE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CENTROSOME; CONTROLLED STUDY; CYTOKINESIS; HETEROCHROMATIN; HYBRID CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MAMMAL CELL; MICROTUBULE ASSEMBLY; MITOSIS RATE; MOUSE; MULTINUCLEAR CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; ANIMAL; CELL STRAIN 3T3; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; METABOLISM; MITOSIS; PHYSIOLOGY; TUMOR CELL LINE;

MAMMALIA; MURINAE;

ANIMALS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CENTROSOME; CHROMOSOMAL PROTEINS, NON-HISTONE; CYTOKINESIS; MICE; MITOSIS; NIH 3T3 CELLS; NUCLEAR PROTEINS; ORIGIN RECOGNITION COMPLEX; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSFECTION; TUBULIN;

EID: 33748590811     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2006.07.014     Document Type: Article

References (61)

1. James T.C., and Elgin S.C. Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene. Mol. Cell. Biol. 6 (1986) 3862-3872
2. Lorentz A., Ostermann K., Fleck O., and Schmidt H. Switching gene swi6, involved in repression of silent mating-type loci in fission yeast, encodes a homologue of chromatin-associated proteins from Drosophila and mammals. Gene 143 (1994) 139-143
3. Couteau F., Guerry F., Muller F., and Palladino F.A. heterochromatin protein 1 homologue in Caenorhabditis elegans acts in germline and vulval development. EMBO Rep. 3 (2002) 235-241
4. Volpe A.M., Horowitz H., Grafer C.M., Jackson S.M., and Berg C.A. Drosophila rhino encodes a female-specific chromo-domain protein that affects chromosome structure and egg polarity. Genetics 159 (2001) 1117-1134
5. Eissenberg J.C., and Elgin S.C. The HP1 protein family: getting a grip on chromatin. Curr. Opin. Genet. Dev. 10 (2000) 204-210
6. Li Y., Kirschmann D.A., and Wallrath L.L. Does heterochromatin protein 1 always follow code?. Proc. Natl. Acad. Sci. U. S. A. 99 Suppl 4 (2002) 16462-16469
7. Minc E., Allory Y., Worman H.J., Courvalin J.C., and Buendia B. Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells. Chromosoma 108 (1999) 220-234
8. Minc E., Allory Y., Courvalin J.C., and Buendia B. Immunolocalization of HP1 proteins in metaphasic mammalian chromosomes. Methods Cell Sci. 23 (2001) 171-174
9. Paro R., and Hogness D.S. The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 263-267
10. Epstein H. Polycomb and friends. BioEssays 14 (1992) 411-413
11. Aasland R., and Stewart A.F. The chromo shadow domain, a second chromo domain in heterochromatin-binding protein 1, HP1. Nucleic Acids Res. 23 (1995) 3168-3173
12. Koonin E.V., Zhou S., and Lucchesi J.C. The chromo superfamily: new members, duplication of the chromo domain and possible role in delivering transcription regulators to chromatin. Nucleic Acids Res. 23 (1995) 4229-4233
13. Brasher S.V., Smith B.O., Fogh R.H., Nietlispach D., Thiru A., Nielsen P.R., Broadhurst R.W., Ball L.J., Murzina N.V., and Laue E.D. The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimmer. EMBO J. 19 (2000) 1587-1597
14. Platero J.S., Hartnett T., and Eissenberg J.C. Functional analysis of the chromo domain of HP1. EMBO J. 14 (1995) 3977-3986
15. Filesi I., Cardinale A., van der Sar S., Cowell I.G., Singh P.B., and Biocca S. Loss of heterochromatin protein 1 (HP1) chromodomain function in mammalian cells by intracellular antibodies causes cell death. J. Cell Sci. 115 (2002) 1803-1813
16. Kellum R., and Alberts B.M. Heterochromatin protein 1 is required for correct chromosome segregation in Drosophila embryos. J. Cell Sci. 108 Pt. 4 (1995) 1419-1431
17. Fanti L., Giovinazzo G., Berloco M., and Pimpinelli S. The heterochromatin protein 1 prevents telomere fusions in Drosophila. Mol. Cell 2 (1998) 527-538
18. Aagaard L., Laible G., Selenko P., Schmid M., Dorn R., Schotta G., Kuhfittig S., Wolf A., Lebersorger A., Singh P.B., Reuter G., and Jenuwein T. Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31. EMBO J. 18 (1999) 1923-1938
19. Melcher M., Schmid M., Aagaard L., Selenko P., Laible G., and Jenuwein T. Structure-function analysis of SUV39H1 reveals a dominant role in heterochromatin organization, chromosome segregation, and mitotic progression. Mol. Cell. Biol. 20 (2000) 3728-3741
20. Jacobs S.A., Taverna S.D., Zhang Y., Briggs S.D., Li J., Eissenberg J.C., Allis C.D., and Khorasanizadeh S. Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3. EMBO J. 20 (2001) 5232-5241
21. Lachner M., O'Carroll D., Rea S., Mechtler K., and Jenuwein T. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410 (2001) 116-120
22. Bannister A.J., Zegerman P., Partridge J.F., Miska E.A., Thomas J.O., Allshire R.C., and Kouzarides T. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410 (2001) 120-124
23. Ryan R.F., Schultz D.C., Ayyanathan K., Singh P.B., Friedman J.R., Fredericks W.J., and Rauscher III F.J. KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kruppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing. Mol. Cell. Biol. 19 (1999) 4366-4378
24. Lechner M.S., Begg G.E., Speicher D.W., and Rauscher III F.J. Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential. Mol. Cell. Biol. 20 (2000) 6449-6465
25. Nielsen S.J., Schneider R., Bauer U.M., Bannister A.J., Morrison A., O'Carroll D., Firestein R., Cleary M., Jenuwein T., Herrera R.E., and Kouzarides T. Rb targets histone H3 methylation and HP1 to promoters. Nature 412 (2001) 561-565
26. Georgatos S.D., and Theodoropoulos P.A. Rules to remodel by: what drives nuclear envelope disassembly and reassembly during mitosis?. Crit. Rev. Eukaryotic Gene Expression 9 (1999) 373-381
27. Kourmouli N., Theodoropoulos P.A., Dialynas G., Bakou A., Politou A.S., Cowell I.G., Singh P.B., and Georgatos S.D. Dynamic associations of heterochromatin protein 1 with the nuclear envelope. EMBO J. 19 (2000) 6558-6568
28. Kourmouli N., Dialynas G., Petraki C., Pyrpasopoulou A., Singh P.B., Georgatos S.D., and Theodoropoulos P.A. Binding of heterochromatin protein 1 to the nuclear envelope is regulated by a soluble form of tubulin. J. Biol. Chem. 276 (2001) 13007-13014
29. Pak D.T., Pflumm M., Chesnokov I., Huang D.W., Kellum R., Marr J., Romanowski P., and Botchan M.R. Association of the origin recognition complex with heterochromatin and HP1 in higher eukaryotes. Cell 91 (1997) 311-323
30. Huang D.W., Fanti L., Pak D.T., Botchan M.R., Pimpinelli S., and Kellum R. Distinct cytoplasmic and nuclear fractions of Drosophila heterochromatin protein 1: their phosphorylation levels and associations with origin recognition complex proteins. J. Cell Biol. 142 (1998) 307-318
31. Prasanth S.G., Prasanth K.V., and Stillman B. Orc6 involved in DNA replication, chromosome segregation, and cytokinesis. Science 297 (2002) 1026-1031
32. Prasanth S.G., Prasanth K.V., Siddiqui K., Spector D.L., and Stillman B. Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance. EMBO J. 23 (2004) 2651-2663
33. Gerbi S.A., and Bielinsky A.K. DNA replication and chromatin. Curr. Opin. Genet. Dev. 12 (2002) 243-248
34. Kneissl M., Putter V., Szalay A.A., and Grummt F. Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. J. Mol. Biol. 327 (2003) 111-128
35. Cowieson N.P., Partridge J.F., Allshire R.C., and McLaughlin P.J. Dimerisation of a chromo shadow domain and distinctions from the chromodomain as revealed by structural analysis. Curr. Biol. 10 (2000) 517-525
36. Zhu Z., Zheng T., Lee C.G., Homer R.J., and Elias J.A. Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modelling. Semin. Cell Dev. Biol. 13 (2002) 121-128
37. Lu B.Y., Emtage P.C., Duyf B.J., Hilliker A.J., and Eissenberg J.C. Heterochromatin protein 1 is required for the normal expression of two heterochromatin genes in Drosophila. Genetics 155 (2000) 699-708
38. Piacentini L., Fanti L., Berloco M., Perrini B., and Pimpinelli S. Heterochromatin protein 1 (HP1) is associated with induced gene expression in Drosophila euchromatin. J. Cell Biol. 161 (2003) 707-714
39. Eissenberg J.C., James T.C., Foster-Hartnett D.M., Hartnett T., Ngan V., and Elgin S.C. Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster. Proc. Natl. Acad. Sci. U. S. A. 87 (1990) 9923-9927
40. Li Y., Danzer J.R., Alvarez P., Belmont A.S., and Wallrath L.L. Effects of tethering HP1 to euchromatic regions of the Drosophila genome. Development 130 (2003) 1817-1824
41. Kellum R. HP1 complexes and heterochromatin assembly. Curr. Top. Microbiol. Immunol. 274 (2003) 53-77
42. Kreitz S., Ritzi M., Baack M., and Knippers R. The human origin recognition complex protein 1 dissociates from chromatin during S phase in HeLa cells. J. Biol. Chem. 276 (2001) 6337-6342
43. DePamphilis M.L. The 'ORC cycle': a novel pathway for regulating eukaryotic DNA replication. Gene 310 (2003) 1-15
44. Ritzi M., Baack M., Musahl C., Romanowski P., Laskey R.A., and Knippers R. Human minichromosome maintenance proteins and human origin recognition complex 2 protein on chromatin. J. Biol. Chem. 273 (1998) 24543-24559
45. Giet R., and Glover D.M. Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis. J. Cell Biol. 152 (2001) 669-682
46. Basu J., Bousbaa H., Logarinho E., Li Z., Williams B.C., Lopes C., Sunkel C.E., and Goldberg M.L. Mutations in the essential spindle checkpoint gene bub1 cause chromosome missegregation and fail to block apoptosis in Drosophila. J. Cell Biol. 146 (1999) 13-28
47. De Lucia F., Ni J.Q., Vaillant C., and Sun F.L. HP1 modulates the transcription of cell-cycle regulators in Drosophila melanogaster. Nucleic Acids Res. 33 (2005) 2852-2858
48. Illenye S., and Heintz N.H. Functional analysis of bacterial artificial chromosomes in mammalian cells: mouse Cdc6 is associated with the mitotic spindle apparatus. Genomics 81 (2004) 66-75
49. Murzina N., Verreault A., Laue E., and Stillman B. Heterochromatin dynamics in mouse cells: interaction between chromatin assembly factor 1 and HP1 proteins. Mol. Cell 4 (1999) 529-540
50. Quivy J.P., Roche D., Kirschner D., Tagami H., Nakatani Y., and Almouzni G. A CAF-1 dependent pool of HP1 during heterochromatin duplication. EMBO J. 23 (2004) 3516-3526
51. Ainsztein A.M., Kandels-Lewis S.E., Mackay A.M., and Earnshaw W.C. INCENP centromere and spindle targeting: identification of essential conserved motifs and involvement of heterochromatin protein HP1. J. Cell Biol. 143 (1998) 1763-1774
52. Fukagawa T. Centromere DNA, proteins and kinetochore assembly in vertebrate cells. Chromosome Res. 12 (2004) 557-567
53. Amor D.J., Kalitsis P., Sumer H., and Choo K.H. Building the centromere: from foundation proteins to 3D organization. Trends Cell Biol. 14 (2004) 359-368
54. Musacchio A., and Hardwick K.G. The spindle checkpoint: structural insights into dynamic signalling. Nat. Rev., Mol. Cell Biol. 3 (2002) 731-741
55. Sharp D.J., Rogers G.C., and Scholey J.M. Microtubule motors in mitosis. Nature 407 (2000) 41-47
56. Nonaka N., Kitajima T., Yokobayashi S., Xiao G., Yamamoto M., Grewal S.I., and Watanabe Y. Recruitment of cohesin to heterochromatic regions by Swi6/HP1 in fission yeast. Nat. Cell Biol. 4 (2002) 89-93
57. Grewal S.I., and Moazed D. Heterochromatin and epigenetic control of gene expression. Science 301 (2003) 798-802
58. Hinchcliffe E.H., and Sluder G. "It takes two to tango": understanding how centrosome duplication is regulated throughout the cell cycle. Genes Dev. 15 (2001) 1167-1181
59. Khodjakov A., and Rieder C.L. Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progression. J. Cell Biol. 153 (2001) 237-242
60. Piel M., Nordberg J., Euteneuer U., and Bornens M. Centrosome-dependent exit of cytokinesis in animal cells. Science 291 (2001) 1550-1553
61. Lange B.M. Integration of the centrosome in cell cycle control, stress response and signal transduction pathways. Curr. Opin. Cell Biol. 14 (2002) 35-43