Centromere DNA, proteins and kinetochore assembly in vertebrate cells

Chromosome Research

Volumn 12, Issue 6, 2004, Pages 557-567

  Fukagawa, Tatsuo ^a  

^a GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

Author keywords

CENP; Centromere; DT40; Kinetochore; Mitosis; Repeat DNA

Indexed keywords

CENTROMERE PROTEIN A; CENTROMERE PROTEIN B; CHROMOSOME PROTEIN; DNA; UNCLASSIFIED DRUG; NONHISTONE PROTEIN;

ARTICLE; BINDING SITE; CENTROMERE; CHROMOSOME ANALYSIS; DNA BINDING; DNA DETERMINATION; DROSOPHILA; HUMAN; MEIOSIS; MICROTUBULE ASSEMBLY; MITOSIS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; TANDEM REPEAT; VERTEBRATE; X CHROMOSOME; YEAST; ANIMAL; CHEMISTRY; CHROMOSOME SEGREGATION; GENETICS; METABOLISM; REVIEW;

EUKARYOTA; VERTEBRATA;

ANIMALS; CENTROMERE; CHROMOSOMAL PROTEINS, NON-HISTONE; CHROMOSOME SEGREGATION; DNA; KINETOCHORES; VERTEBRATES;

EID: 12344327774     PISSN: 09673849     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:CHRO.0000036590.96208.83     Document Type: Article

References (68)

1. Ahmad K, Henikoff S (2002) The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly. Mol Cell 9: 1191-1200.
2. Bharadwaj R, Qi W, Yu H (2004) Identification of two novel components of the human Ndc80 kinetochore complex. J Biol Chem 279: 13076-13085.
3. Blower MD, Karpen GH (2001) The role of Drosophila CID in kinetochore formation, cell-cycle progression and heterochromatin interactions. Nat Cell Biol 3: 730-739.
4. Blower MD, Sullivan BA, Karpen GH (2002) Conserved organization of centromeric chromatin in flies and humans. Dev Cell 2: 319-330.
5. Brown MT, Goetsch L, Hartwell LH (1993) MIF2 is required for mitotic integrity during anaphase spindle elongation in Sacchromyces cerevisiae. J Cell Biol 123: 387-403.
6. Brown WR, Mee PJ, Shen MH (2000) Artificial chromosomes: ideal vectors? Trends Biotechnol 18: 218-223.
7. Brown WR, Hubbard SJ, Tickle C, Wilson SA (2003) The chicken as a model for large-scale analysis of vertebrate gene function. Nat Rev Genet 4: 87-98.
8. Cahill DP, Lengauer C, Yu J et al. (1998) Mutations of mitotic checkpoint genes in human cancers. Nature 392: 300-303.
9. Carmena M, Earnshaw WC (2003) The cellular geography of aurora kinases. Nat Rev Mol Cell Biol 4: 842-854.
10. Chen ES, Saitoh S, Yanagida M, Takahashi K (2003) A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast. Mol Cell 11: 175-187.
11. Choo KH (2001) Domain organization at centromere and neocentromere. Dev Cell 1: 165-177.
12. Cleveland DW, Mao Y, Sullivan KF (2003) Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell 112: 407-421.
13. Compton DA, Yen TJ, Cleveland DW (1991) Identification of novel centromere/kinetochore-associated proteins using monoclonal antibodies generated against human mitotic chromosome scaffolds. J Cell Biol 112: 1083-1097.
14. Craig JM, Earnshaw WC, Vagnarelli P (1999) Mammalian centromeres: DNA sequence, protein composition, and role in cell cycle progression. Exp Cell Res 246: 249-262.
15. DeLuca JG, Howell BJ, Canman JC, Hickey JM, Fang G, Salmon ED (2003) Nuf2 and Hec1 are required for retention of the checkpoint proteins Mad1 and Mad2 to kinetochores. Curr Biol 13: 2103-2109.
16. Floridia G, Zatterale A, Zuffardi O, Tyler-Smith C (2000) Mapping of a human centromere onto the DNA by topoisomerase II cleavage. EMBO Rep 1: 489-493.
17. Fukagawa T, Brown WRA (1997) Efficient conditional mutation of the vertebrate CENP-C gene. Hum Mol Genet 6: 2301-2308.
18. Fukagawa T, Pendon C, Morris J, Brown W (1999) CENP-C is necessary but not sufficient to induce formation of functional centromere. EMBO J 18: 4196-4209.
19. Fukagawa T, Mikami Y, Nishihashi A et al. (2001) CENP-H, a constitutive centromere component, is required for centromere targeting of CENP-C in vertebrate cells. EMBO J 20: 4603-4617.
20. Goshima G, Saitoh S, Yanagida M (1999) Proper metaphase spindle length is determined by centromere proteins Mis12 and Mis6 required for faithful chromosome segregation. Genes Dev 13: 1664-1677.
21. Goshima G, Kiyomitsu T, Yoda K, Yanagida M (2003) Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway. J Cell Biol 160: 25-39.
22. Hall IM, Noma K, Grewal SI (2003) RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast. Proc Natl Acad Sci USA 100: 193-198.
23. Harrington JJ, Van Bokkelen G, Mays RW, Gustashaw K, Willard HF (1997) Formation of de novo centromeres and construction of first-generation human artificial microchromosomes. Nat Genet 15: 345-355.
24. Hori T, Haraguchi T, Hiraoka Y, Kimura H, Fukagawa, T (2003) Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells. J Cell Sci 116: 3347-3362.
25. Howman EV, Fowler KJ, Newson AJ et al. (2000) Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice. Proc Natl Acad Sci USA 97: 1148-1153.
26. Hudson DF, Fowler KJ, Earle E et al. (1998) Centromere protein B null mice are mitotically and meiotically normal but have lower body and testis weights. J Cell Biol 141: 309-319.
27. Ikeno M, Grimes B, Okazaki T et al. (1998) Construction of YAC-based mammalian artificial chromosomes. Nat Biotechnol 16: 431-439.
28. Janke C, Ortiz Jhechner et al. (2001) The budding yeast proteins Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control. EMBO J 20: 777-791.
29. Kalitsis P, Fowler KJ, Earle E, Hill J, Choo KHA (1998) Targeted disruption of mouse centromere protein C gene leads to mitotic disarray and early embryo death. Proc Natl Acad Sci USA 95: 576-582.
30. Kallio M, Weinstein J, Daurn JR, Burke DJ, Gorbsky GJ (1998) Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events. J Cell Biol 141: 1393-1406.
31. Kallio MJ, Beardmore VA, Weinstein J, Gorbsky GJ (2002) Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells. J Cell Biol 158: 841-847.
32. Karpen GH, Allshire, RC (1997) The case for epigenetic effects on centromere identity and function. Trends Genet 13: 489-496.
33. Liu ST, Hittle JC, Jablonski SA, Campbell MS, Yoda K, Yen TJ (2003) Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis. Nat Cell Biol 5: 341-345.
34. Malik HS, Henikoff S (2002) Conflict begets complexity: the evolution of centromeres. Curr Opin Genet Dev 12: 711-718.
35. Martin-Lluesma S, Stucke VM, Nigg EA (2002) Role of Heel in spindle checkpoint signaling and kinetochore recruitment of Madl/Mad2. Science 297: 2267-2270.
36. Masumoto H, Masukata H, Muro Y, Nozaki N, Okazaki T (1989) A human centromere antigen (CENP-B) interacts with a short specific sequence in alphoid DNA, a human centromeric satellite. J Cell Biol 109: 1963-1973.
37. McCleland ML, Kallio MJ, Barrett-Wilt GA et al. (2004) The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment. Curr Biol 14: 131-137.
38. Measday V, Hailey DW, Pot I et al. (2002) Ctf3, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore. Genes Dev 16: 101-113.
39. Mellone BG, Allshire RC (2003) Stretching it: putting the CEN(P-A) in centromere. Curr Opin Cell Biol 13: 191-198.
40. Meluh PB, Koshland D (1995) Evidence that the Mif2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C. Mol Biol Cell 6: 793-807.
41. Moroi Y, Peebles C, Fritzler MJ, Steigerwald J, Tan EM (1980) Autoantibody to centromere (kinetochore) in scleroderma sera. Proc Natl Acad Sci USA 77: 1627-1631.
42. Nakagawa H, Lee JK, Hurwitz J et al. (2002) Fission yeast CENP-B homologs nucleate centromeric heterochromatin by promoting heterochromatin-specific histone tail modifications. Genes Dev 16: 1766-1778.
43. Nishihashi A, Haraguchi T, Hiraoka Y et al. (2002) CENP-I is essential for centromere function in vertebrate cells. Dev Cell 2: 463-476.
44. Ohzeki J, Nakano M, Okada T, Masumoto H (2002) CENP-B box is required for de novo centromere chromatin assembly on human alphoid DNA. J Cell Biol 159: 765-775.
45. Palmer DK, Margolis RL (1987) A 17-kD centromere protein (CENP-A) copurifies with nucleosome core particles and with histones. J Cell Biol 104: 805-815.
46. Partridge JF, Scott KS, Bannister AJ, Kouzarides T, Allshire RC (2002) cis-acting DNA from fission yeast centromeres mediates histone H3 methylation and recruitment of silencing factors and cohesin to an ectopic site. Curr Biol 12: 1652-1660.
47. Pluta AF, Mackay AM, Ainsztein AM, Goldberg IG, Earnshaw WC (1995) The centromere: Hub of chromosomal activities. Science 270: 1591-1594.
48. Provost P, Silverstein RA, Dishart D et al. (2002) Dicer is required for chromosome segregation and gene silencing in fission yeast cells. Proc Natl Acad Sci USA 99: 16648-16653.
49. Ray-Gallet D, Quivy JP, Scamps C, Martini EM, Lipinski M, Almouzni G (2002) HIRA is critical for a nucleosome assembly pathway independent of DNA synthesis. Mol Cell 9: 1091-1100.
50. Saitoh H, Tomkiel J, Cooke CA et al. (1992) CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate. Cell 70: 115-125.
51. Saitoh S, Takahashi K, Yanagida M (1997) Mis6, a fission yeast inner centromere protein, acts during G1/S and forms specialized chromatin required for equal segregation. Cell 90: 131-143.
52. Shelby RD, Vafa O, Sullivan KF (1997) Assembly of CENP-A into centromere chromatin requires a cooperative array of nucleosomal DNA contact sites. J Cell Biol 136: 501-513.
53. Spence JM, Critcher R, Ebersole TA et al. (2002) Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array. EMBO J 21: 5269-5280.
54. Sugata N, Munekata E, Todokoro K (1999) Characterization of a novel kinetochore protein, CENP-H. J Biol Chem 274: 27343-27346.
55. Sugata N, Li S, Earnshaw WC et al. (2000) Human CENP-H multimers colocalize with CENP-A and CENP-C at active centromere-kinetochore complexes. Hum Mol Genet 9: 2919-2926.
56. Sullivan BA (2002) Centromere round-up at the heterochromatin corral. Trends Biotechnol 20: 89-92.
57. Sullivan BA, Schwartz S (1995) Identification of centromeric antigens in dicentric Robertsonian translocations: CENP-C and CENP-E are necessary components of functional centromeres. Hum Mol Genet 4: 2189-2197.
58. Sullivan BA, Blower MD, Karpen GH (2001) Determining centromere identity: cyclical stories and forking path. Nat Rev Genet 2: 584-596.
59. Sullivan KF (2001) A solid foundation: functional specialization of centromeric chromatin. Curr Opin Genet Dev 11: 182-188.
60. Tagami H, Ray-Gallet D, Almouzni G, Nakatani Y (2004) Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis. Cell 116: 51-61.
61. Takahashi K, Chen ES, Yanagida M (2000) Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast. Science 288: 2215-2219.
62. Tomkiel J, Cooke CA, Saitoh H, Bernat RL, Earnshaw WC (1994) CENP-C is required for maintaining proper kinetochore size and for a timely transition to anaphase. J Cell Biol 125: 531-545.
63. Volpe TA, Kidner C, Hall IM, Teng G, Grewal SI, Martienssen RA (2002) Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science 297: 1833-1837.
64. Volpe T, Schramke V, Hamilton GL et al. (2003) RNA interference is required for normal centromere function in fission yeast. Chromosome Res 11: 137-146.
65. Warburton PE, Cooke CA, Bourassa S et al. (1997) Immunolocalization of CENP-A suggests a novel nucleosome structure at the inner kinetochore plate of active centromeres. Curr Biol 7: 901-904.
66. Wiens GR, Soger PK (1998) Centromeric chromatin and epigenetic effects in kinetochore assembly. Cell 93: 313-316.
67. Wigge PA, Kilmartin JV (2001) The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation. J Cell Biol 152: 349-360.
68. Yang CH, Tomkiel J, Saitoh H, Johnson DH, Earnshaw WC (1996) Identification of overlapping DNA-binding and centromere-targeting domains in the human kinetochore protein CENP-C. Mol Cell Biol 16: 3576-3586.