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Volumn 135, Issue 1, 2006, Pages 129-138

Downregulation of hepcidin and haemojuvelin expression in the hepatocyte cell-line HepG2 induced by thalassaemic sera

Author keywords

Haemochromatosis; Haemojuvelin; Hepcidin; Iron; Thalassaemia

Indexed keywords

HEPCIDIN; LIPOCALIN2; TRANSFERRIN; UNCLASSIFIED DRUG;

EID: 33748370295     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2006.06258.x     Document Type: Article
Times cited : (64)

References (46)
  • 3
    • 10844240718 scopus 로고    scopus 로고
    • Cell biology. 'Pumping' iron: The proteins
    • Beutler, E. (2004) Cell biology. 'Pumping' iron: the proteins. Science, 306, 2051-2053.
    • (2004) Science , vol.306 , pp. 2051-2053
    • Beutler, E.1
  • 8
    • 0036727925 scopus 로고    scopus 로고
    • Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats
    • Frazer, D.M., Wilkins, S.J., Becker, E.M., Vulpe, C.D., McKie, A.T., Trinder, D. & Anderson, G.J. (2002) Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats. Gastroenterology, 123, 835-844.
    • (2002) Gastroenterology , vol.123 , pp. 835-844
    • Frazer, D.M.1    Wilkins, S.J.2    Becker, E.M.3    Vulpe, C.D.4    McKie, A.T.5    Trinder, D.6    Anderson, G.J.7
  • 9
    • 0041672570 scopus 로고    scopus 로고
    • Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation
    • Ganz, T. (2003) Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation. Blood, 102, 783-788.
    • (2003) Blood , vol.102 , pp. 783-788
    • Ganz, T.1
  • 10
    • 0036865552 scopus 로고    scopus 로고
    • The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition
    • Goetz, D.H., Holmes, M.A., Borregaard, N., Bluhm, M.E., Raymond, K.N. & Strong, R.K. (2002) The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition. Molecular Cell, 10, 1033-1043.
    • (2002) Molecular Cell , vol.10 , pp. 1033-1043
    • Goetz, D.H.1    Holmes, M.A.2    Borregaard, N.3    Bluhm, M.E.4    Raymond, K.N.5    Strong, R.K.6
  • 11
    • 0036439058 scopus 로고    scopus 로고
    • A review of the molecular diagnosis of thalassemia
    • Gu, X. & Zeng, Y. (2002) A review of the molecular diagnosis of thalassemia. Hematology, 7, 203-209.
    • (2002) Hematology , vol.7 , pp. 203-209
    • Gu, X.1    Zeng, Y.2
  • 14
    • 23044442033 scopus 로고    scopus 로고
    • Hematologic and clinical responses of thalassemia intermedia patients to hydroxyurea during 6 years of therapy in Iran
    • Karimi, M., Darzi, H. & Yavarian, M. (2005) Hematologic and clinical responses of thalassemia intermedia patients to hydroxyurea during 6 years of therapy in Iran. Journal of Pediatric Hematology/Oncology, 27, 380-385.
    • (2005) Journal of Pediatric Hematology/Oncology , vol.27 , pp. 380-385
    • Karimi, M.1    Darzi, H.2    Yavarian, M.3
  • 20
    • 10244225221 scopus 로고    scopus 로고
    • Expression of Rgmc, the murine ortholog of hemojuvelin gene, is modulated by development and inflammation, but not by iron status or erythropoietin
    • Krijt, J., Vokurka, M., Chang, K.T. & Necas, E. (2004) Expression of Rgmc, the murine ortholog of hemojuvelin gene, is modulated by development and inflammation, but not by iron status or erythropoietin. Blood, 104, 4308-4310.
    • (2004) Blood , vol.104 , pp. 4308-4310
    • Krijt, J.1    Vokurka, M.2    Chang, K.T.3    Necas, E.4
  • 22
    • 27144459908 scopus 로고    scopus 로고
    • Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin
    • Lin, L., Goldberg, Y.P. & Ganz, T. (2005) Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin. Blood, 106, 2884-2889.
    • (2005) Blood , vol.106 , pp. 2884-2889
    • Lin, L.1    Goldberg, Y.P.2    Ganz, T.3
  • 25
    • 0038662619 scopus 로고    scopus 로고
    • Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein
    • Nemeth, E., Valore, E.V., Territo, M., Schiller, G., Lichtenstein, A. & Ganz, T. (2003) Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood, 101, 2461-2463.
    • (2003) Blood , vol.101 , pp. 2461-2463
    • Nemeth, E.1    Valore, E.V.2    Territo, M.3    Schiller, G.4    Lichtenstein, A.5    Ganz, T.6
  • 26
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth, E., Tuttle, M.S., Powelson, J., Vaughn, M.B., Donovan, A., Ward, D.M., Ganz, T. & Kaplan, J. (2004) Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science, 306, 2090-2093.
    • (2004) Science , vol.306 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3    Vaughn, M.B.4    Donovan, A.5    Ward, D.M.6    Ganz, T.7    Kaplan, J.8
  • 27
  • 32
    • 0031001278 scopus 로고    scopus 로고
    • Iron-chelating therapy and the treatment of thalassemia
    • Olivieri, N.F. & Brittenham, G.M. (1997) Iron-chelating therapy and the treatment of thalassemia. Blood, 89, 739-761.
    • (1997) Blood , vol.89 , pp. 739-761
    • Olivieri, N.F.1    Brittenham, G.M.2
  • 36
    • 0035896581 scopus 로고    scopus 로고
    • A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
    • Pigeon, C., Ilyin, G., Courselaud, B., Leroyer, P., Turlin, B., Brissot, P. & Loreal, O. (2001) A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. Journal of Biological Chemistry, 276, 7811-7819.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 7811-7819
    • Pigeon, C.1    Ilyin, G.2    Courselaud, B.3    Leroyer, P.4    Turlin, B.5    Brissot, P.6    Loreal, O.7
  • 38
    • 0030976033 scopus 로고    scopus 로고
    • Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency
    • Punnonen, K., Irjala, K. & Rajamaki, A. (1997) Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency. Blood, 89, 1052-1057.
    • (1997) Blood , vol.89 , pp. 1052-1057
    • Punnonen, K.1    Irjala, K.2    Rajamaki, A.3
  • 39
    • 10244255021 scopus 로고    scopus 로고
    • Regulation of transferrin receptor 2 protein levels by transferrin
    • Robb, A. & Wessling-Resnick, M. (2004) Regulation of transferrin receptor 2 protein levels by transferrin. Blood, 104, 4294-4299.
    • (2004) Blood , vol.104 , pp. 4294-4299
    • Robb, A.1    Wessling-Resnick, M.2
  • 41
    • 0037369165 scopus 로고    scopus 로고
    • 2002 E. Mead Johnson Award for Research in Pediatrics Lecture: The molecular biology of the anemia of chronic disease: A hypothesis
    • Roy, C.N., Weinstein, D.A. & Andrews, N.C. (2003) 2002 E. Mead Johnson Award for Research in Pediatrics Lecture: the molecular biology of the anemia of chronic disease: a hypothesis. Pediatric Research, 53, 507-512.
    • (2003) Pediatric Research , vol.53 , pp. 507-512
    • Roy, C.N.1    Weinstein, D.A.2    Andrews, N.C.3
  • 43
    • 0019450469 scopus 로고
    • Molecular basis for mild forms of homozygous beta-thalassaemia
    • Weatherall, D.J., Pressley, L., Wood, W.G., Higgs, D.R. & Clegg, J.B. (1981) Molecular basis for mild forms of homozygous beta-thalassaemia. Lancet, 1, 527-529.
    • (1981) Lancet , vol.1 , pp. 527-529
    • Weatherall, D.J.1    Pressley, L.2    Wood, W.G.3    Higgs, D.R.4    Clegg, J.B.5
  • 44
    • 0037111732 scopus 로고    scopus 로고
    • Inappropriate expression of hepcidin is associated with iron refractory anemia: Implications for the anemia of chronic disease
    • Weinstein, D.A., Roy, C.N., Fleming, M.D., Loda, M.F., Wolfsdorf, J.I. & Andrews, N.C. (2002) Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood, 100, 3776-3781.
    • (2002) Blood , vol.100 , pp. 3776-3781
    • Weinstein, D.A.1    Roy, C.N.2    Fleming, M.D.3    Loda, M.F.4    Wolfsdorf, J.I.5    Andrews, N.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.