Specific interaction of CXCR4 with CD4 and CD8α: Functional analysis of the CD4/CXCR4 interaction in the context of HIV-1 envelope glycoprotein-mediated membrane fusion

Virology

Volumn 353, Issue 1, 2006, Pages 52-67

  Basmaciogullari, Stéphane ^a,b   Pacheco, Beatriz ^a,b   Bour, Stephan ^d   Sodroski, Joseph ^a,b,c  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

CD4; CD8 ; CXCR4; Fusion inhibitors; HIV 1; Immunological synapse; Membrane fusion

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; VIRUS GLYCOPROTEIN;

ARTICLE; COMPLEX FORMATION; CYTOPLASM; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MEMBRANE FUSION; MOLECULE; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; VIRUS ENVELOPE;

ANTIGENS, CD4; ANTIGENS, CD8; CELL LINE; HIV-1; HUMANS; MEMBRANE FUSION; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CCR5; RECEPTORS, CXCR4; RECOMBINANT FUSION PROTEINS; VIRAL ENVELOPE PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 33747875258     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2006.05.027     Document Type: Article

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