Enhanced expression, native purification, and characterization of CCR5, a principal HIV-1 coreceptor

Journal of Biological Chemistry

Volumn 274, Issue 40, 1999, Pages 28745-28750

  Mirzabekov, Tajib ^a,b   Bannert, Norbert ^a,b   Farzan, Michael ^a,b   Hofmann, Wolfgang ^a,b   Kolchinsky, Peter ^a,b   Wu, Lijun ^c   Wyatt, Richard ^a,b   Sodroski, Joseph ^a,b,d  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MILLENNIUM PHARMACEUTICALS INC   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; GLYCOPROTEIN GP 120;

ARTICLE; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN PURIFICATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; CLONING, MOLECULAR; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HIV ENVELOPE PROTEIN GP120; HUMANS; PROTEIN BINDING; RECEPTORS, CCR5;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MAMMALIA; RNA VIRUSES;

EID: 0033214480     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.40.28745     Document Type: Article

References (39)

1. Littman, D. R. (1998) Cell 93, 677-680
2. Wyatt, R., and Sodroski, J. G. (1998) Science 280, 1884-1888
3. Wu, L., Gerary, N. P., Wyatt, R., Choe, H., Parolin, C., Ruffing, N., Borsetti, A., Dardoso, A. A., Desjardin, E., Newman, W., Gerard, C., and Sodroski, J. (1996) Nature 384, 179-183
4. Trkola, A., Dragic, T., Arthos, J., Binley, J. M., Olson, W. C., Allaway, G. P., Cheng-Mayer, C., Robinson, J., Maddon, P. J., and Moore, J. P. (1996) Nature 384, 184-187
5. Carr, C. M., and Kim, P. S. (1994) Science. 266, 234-236
6. Bullough, P. A., Hughson, F. M., Skehel, J. J., and Wiley, D. C. (1994) Nature 371, 37-43
7. Alkhatib, G., Combadiere, C., Broder, C. C., Feng, Y., Kennedy, P. E., Murphy, P. M., and Berger, E. A. (1996) Science 272, 1955-1958
8. Choe, H., Farzan, M., Sun, Y., Sullivan, N., Rollins, B., Ponath, P. D., Wu, L., Mackay, C. R., LaRosa, G., Newman, W., Gerard, N., Gerard, G., and Sodroski, J. (1996) Cell 85, 1135-1148
9. Deng, H., Liu, R., Ellmeier, W., Choe, S., Unutmaz, D., Burkhart, M., Di Marzio, P., Marmon, S., Sutton, R. E., Hill, C. M., Davis, C. B., Peiper, S. C., Schall, T. J., Littman, D. R., and Landau, N. R. (1996) Nature 381, 661-666
10. Doranz, B. J., Rucker, J., Yi, Y., Smyth, R. J., Samson, M., Peiper, S. C., Parmentier, M., Collman, R. G., and Doms, R. W. (1996) Cell 85, 1149-1158
11. Dragic, T., Litwin, V., Allaway, G. P., Martin, S. R., Huang, Y., Nagashima, K. A., Cayanan, C., Maddon, P. J., Koup, R. A., Moore, J. P., and Paxton, W. A. (1996) Nature 381, 667-673
12. Samson, M., Libert, F., Doranz, B. J., Rucker, J., Liesnard, C., Farber, C. M., Saragosti, S., Lapoumeroulie, C., Cognaux, J., Forceille, C., Muyldermans, G., Verhofstede, C., Burtonboy, G., Georges, M., Imai, T., Rana, S., Yi, Y., Smyth. R. J., Collman, R. G., Doms, R. W., Vassart, G., Parmentier, M. (1996) Nature 382, 722-725
13. Liu, R., Paxton, W. A., Choe, S., Ceradini, D., Martin, S. R., Horuk, R., MacDonald, M. E., Stuhlmann, H., Koup, R. A., and Landau, N. R. (1996) Cell 86, 367-377
14. Dumonceaux, J., Nisole, S., Chanel, C., Quivet, L., Amara, A., Baleux, F., Briand, P., and Hazan, U. (1998) J. Virol. 72, 512-519
15. Huttner, W. B. (1988) Annu. Rev. Physiol. 50, 363-376
16. Hoffman, T. L., LaBranche, C. C., Zhang, W., Canziani, G., Robinson, J., Chaiken, I., Hoxie, J. A., and Doms, R. W. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 6359-6364
17. Feng, Y., Broder, C. C., Kennedy, P. E., Berger, E. A. (1996) Science 272, 872-877
18. Ryu, S. E., Kwong, P. D., Truneh, A., Porter, T. G., Arthos, J., Rosenberg, M., Dai, X. P., Xuong, N. H., Axel, R., Sweet, R. W., and Hendrickson, W. A. (1990) Nature 348, 419-426
19. Wang, J. H., Yan, Y. W., Garrett, T. P., Liu, J. H., Rodgers, D. W., Garlick, R. L., Tarr, G. E., Husain, Y., Reinherz, E. L., and Harrison, S. C. (1990) Nature 348, 411-418
20. Wu, H., Kwong, P. D., and Hendrickson, W. A. (1997) Nature 387, 527-530
21. Kwong, P. D., Wyatt, R., Robinson, J., Sweet, R. W., Sodroski, J., and Hendrickson, W. A. (1998) Nature 393, 648-659
22. Wyatt, R., Kwong, P. D., Desjardins, E., Sweet, R. W., Robinson, J., Hendrickson, W. A., and Sodroski, J. G. (1998) Nature 393, 705-711
23. Chan, D. C., Fass, D., Berger, J. M., and Kim, P. S. (1997) Cell 89, 263-273
24. Weissenhorn, W., Dessen, A., Harrison, S. C., Skehel, J. J., and Wiley, D. C. (1997) Nature 387, 426-430
25. Tan, K., Liu, J., Wang, J., Shen, S., and Lu, M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 12303-12308
26. Stadel, J. M., Wilson, S., and Bergsma, D. J. (1997) Trends Pharmacol. Sci. 18, 430-437
27. Helmreich, E. J. M., and Hofmann, K. P. (1996) Biochim. Biophys. Acta 1286, 285-322
28. Bikker, J. A., Trumpp-Kallmeyer, S., and Humblet, C. (1998) J. Med. Chem. 41, 2911-2927
29. Lanyi, J. K. (1999) Int. Rev. Cytol. 187, 161-202
30. Khorana, H. G. (1992) J. Biol. Chem. 267, 1-4
31. Stanasila, L., Pattus, F., and Massotte, D. (1998) Biochimie 80, 563-571
32. Tate, C. G., and Grisshammer, R. (1996) Trends Biotechnol. 14, 426-430
33. Farzan, M., Mirzabekov, T., Kolchinsky, P., Wyatt, R., Cayabyab, M., Gerard, N., Gerard, G., Sodroski, J., and Choe, H. (1999) Cell 96, 667-676
34. Andre, S., Seed, B., Eberle, J., Schraut, W., Bultmann, A., and Haas, J. (1998) J. Virol. 72, 1497-1503
35. Oprian, D. D., Molday, R. S., Kaufman, R. J., and Korana, G. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 8874-8878
36. Wu, L., LaRosa, G., Kassam, N., Gordon, C. J., Heath, H., Ruffing, N., Chen, H., Humblias, J., Samson, M., Parmentier, M., Moore, J. P., and Mackay, C. R. (1997) J. Exp. Med. 186, 1373-1381
37. Hamaguchi, K. (1992) The Protein Molecule. Conformation, Stability and Folding, Japan Scientific Societies Press, Springer-Verlag, New York
38. Reeves, P., Thurmond, R. L., and Khorana, G. H. (1996) Proc. Natl. Acad. Sci. U. S. A. 94, 7784-7790
39. Jones, M. N. (1999) Int. J. Pharm. 177, 137-159