Structure and interactions of the ubiquitin-conjugating enzyme variant human Uev1a: Implications for enzymatic synthesis of polyubiquitin chains

Biochemistry

Volumn 45, Issue 32, 2006, Pages 9866-9877

  Hau, D Duong ^a   Lewis, Michael J ^a   Saltibus, Linda F ^a   Pastushok, Landon ^b   Xiao, Wei ^b   Spyracopoulos, Leo ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CATALYSIS; DIMERS; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; SPECTROSCOPIC ANALYSIS; SYNTHESIS (CHEMICAL);

AMINO GROUP; MOLECULAR DYNAMICS SIMULATIONS; POLYUBIQUITINATION;

ENZYMES;

AMINO ACID; ASPARTIC ACID; CARBON; CARBONYL DERIVATIVE; GLUTAMIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYSINE; POLYUBIQUITIN; PROTEIN HUEV1A; SOLVENT; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; THIOESTER; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN CONJUGATING ENZYME E2; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONJUGATION; COVALENT BOND; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HUMAN; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTON TRANSPORT; SIGNAL TRANSDUCTION; STRUCTURAL PROTEOMICS; UBIQUITINATION;

DIMERIZATION; HUMANS; LIGASES; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POLYUBIQUITIN; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; SOLUTIONS; TITRIMETRY; TRANSCRIPTION FACTORS; UBIQUITIN-CONJUGATING ENZYMES;

EID: 33747459664     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi060631r     Document Type: Article

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