General anesthesia activates BDNF-dependent neuroapoptosis in the developing rat brain

Apoptosis

Volumn 11, Issue 9, 2006, Pages 1603-1615

  Lu, Lucy X ^a   Yon, Jun Heum ^a,b   Carter, Lisa B ^a   Jevtovic Todorovic, Vesna ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b Inje University College of Medicine   (South Korea)

Author keywords

estradiol; Akt; Caspase; Ceramide; Neurotoxicity; Neurotrophins; p75NTR; Synaptogenesis

Indexed keywords

ANESTHETIC AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; ESTRADIOL; ISOFLURANE; MIDAZOLAM; NITROUS OXIDE; PROTEIN P75; PROTEIN P75NTR; TROPOMYOSIN RECEPTOR KINASE RECEPTOR; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; BRAIN REGION; CELL DEGENERATION; CELL PROTECTION; CONTROLLED STUDY; GENERAL ANESTHESIA; HISTOPATHOLOGY; HORMONAL REGULATION; NERVE CELL; NEUROAPOPTOSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTOGENESIS; THALAMUS; TIME; WESTERN BLOTTING;

ANESTHESIA, GENERAL; ANESTHETICS; ANIMALS; APOPTOSIS; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CEREBRAL CORTEX; DOWN-REGULATION; ESTRADIOL; MODELS, BIOLOGICAL; NERVE DEGENERATION; NEURONS; ONCOGENE PROTEIN V-AKT; ONCOGENE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY INSUFFICIENCY; SIGNAL TRANSDUCTION; THALAMUS;

EID: 33747444621     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-006-8762-3     Document Type: Article

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