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Volumn 4, Issue 3, 2006, Pages 217-223

PDZ domains at excitatory synapses: Potential molecular targets for persistent pain treatment

Author keywords

AMBA receptors; Chronic pain; NMDA receptors; Persistent pain; PSD 93; PSD 95; Spinal cord; Trafficking

Indexed keywords

AMPA RECEPTOR ANTAGONIST; CELL PROTEIN; GLUTAMATE RECEPTOR ANTAGONIST; MEMBRANE PROTEIN; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEURONAL NITRIC OXIDE SYNTHASE; PDZ PROTEIN; POSTSYNAPTIC DENSITY PROTEIN 93; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN KINASE (CALCIUM,CALMODULIN) II; UNCLASSIFIED DRUG;

EID: 33747244407     PISSN: 1570159X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157015906778019473     Document Type: Review
Times cited : (13)

References (65)
  • 2
    • 1842535186 scopus 로고    scopus 로고
    • Molecular Mechanisms Underlying Specificity of Excitotoxic Signaling in Neurons
    • Aarts, M.M., Tymianski, M. (2004) Molecular Mechanisms Underlying Specificity of Excitotoxic Signaling in Neurons. Curr. Mol. Med., 4, 137-147.
    • (2004) Curr. Mol. Med. , vol.4 , pp. 137-147
    • Aarts, M.M.1    Tymianski, M.2
  • 3
    • 0031913847 scopus 로고    scopus 로고
    • Sensitization of pain pathways in the spinal cord: Cellular mechanisms
    • Baranauskas, G., Nistri, A. (1998) Sensitization of pain pathways in the spinal cord: cellular mechanisms. Prog. Neurobiol. 54, 349-365.
    • (1998) Prog. Neurobiol. , vol.54 , pp. 349-365
    • Baranauskas, G.1    Nistri, A.2
  • 5
    • 0029959179 scopus 로고    scopus 로고
    • Cloning and characterization of postsynaptic density 93, a nitric oxide synthase interacting protein
    • Brenman, J. E., Christopherson, K. S., Craven, S. E., McGee, A. W., Bredt, D. S. (1996) Cloning and characterization of postsynaptic density 93, a nitric oxide synthase interacting protein. J. Neurosci., 16, 7407-7415.
    • (1996) J. Neurosci. , vol.16 , pp. 7407-7415
    • Brenman, J.E.1    Christopherson, K.S.2    Craven, S.E.3    McGee, A.W.4    Bredt, D.S.5
  • 6
    • 17344367357 scopus 로고    scopus 로고
    • Localization of postsynaptic densssity-93 to dendritic microtabules and interaction with microtabule-associated protein 1A
    • Brenman, J.E., Topinka, J.R., Cooper, E.C., McGee, A.W., Rosen, J., Milroy, T., Ralston, H.J., Bredt, D.S. (1998) Localization of postsynaptic densssity-93 to dendritic microtabules and interaction with microtabule-associated protein 1A. J. Neurosci., 18, 8805-8813.
    • (1998) J. Neurosci. , vol.18 , pp. 8805-8813
    • Brenman, J.E.1    Topinka, J.R.2    Cooper, E.C.3    McGee, A.W.4    Rosen, J.5    Milroy, T.6    Ralston, H.J.7    Bredt, D.S.8
  • 7
    • 0036828497 scopus 로고    scopus 로고
    • NMDA-receptor trafficking and targeting: Implications for synaptic transmission and plasticity
    • Carroll, R.C., Zukin, R.S. (2002) NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity. Trends Neurosci., 25, 571-577.
    • (2002) Trends Neurosci. , vol.25 , pp. 571-577
    • Carroll, R.C.1    Zukin, R.S.2
  • 9
    • 0032078872 scopus 로고    scopus 로고
    • A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II
    • Chen, H.J., Rojas-Soto, M., Oguni, A., Kennedy, M.B. (1998) A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II. Neuron, 20, 895-904.
    • (1998) Neuron , vol.20 , pp. 895-904
    • Chen, H.J.1    Rojas-Soto, M.2    Oguni, A.3    Kennedy, M.B.4
  • 10
    • 0036386818 scopus 로고    scopus 로고
    • Novel approaches to targeting glutamate receptors for the treatment of chronic pain: Review article
    • Chizh, B.A. (2002) Novel approaches to targeting glutamate receptors for the treatment of chronic pain: review article. Amino Acids, 23, 169-176.
    • (2002) Amino Acids , vol.23 , pp. 169-176
    • Chizh, B.A.1
  • 11
    • 0026492629 scopus 로고
    • The rat brain post-synaptic density fraction contains a homology of the drosophila discs-large tumor suppressor protein
    • Cho, K.-O., Hunt, C.A., Kennedy, M.B. (1992) The rat brain post-synaptic density fraction contains a homology of the drosophila discs-large tumor suppressor protein. Neuron, 9, 929-942.
    • (1992) Neuron , vol.9 , pp. 929-942
    • Cho, K.-O.1    Hunt, C.A.2    Kennedy, M.B.3
  • 12
    • 28644442118 scopus 로고    scopus 로고
    • Effect of genetic knockout or pharmacologic inhibition of neuronal nitric oxide synthase on complete Freund's adjuvant-induced persistent pain
    • Chu, Y.C., Guan, Y., Skinner, J., Raja, S.N., Johns, R.A., Tao, Y.-X. (2005) Effect of genetic knockout or pharmacologic inhibition of neuronal nitric oxide synthase on complete Freund's adjuvant-induced persistent pain. Pain, 119, 113-123.
    • (2005) Pain , vol.119 , pp. 113-123
    • Chu, Y.C.1    Guan, Y.2    Skinner, J.3    Raja, S.N.4    Johns, R.A.5    Tao, Y.-X.6
  • 13
    • 0035369112 scopus 로고    scopus 로고
    • NMDA receptor subunits: Diversity, development, and disease
    • Cull-Candy, S., Brickley, S., Farrant, M. (2001) NMDA receptor subunits: diversity, development, and disease. Curr. Opin. Neurobiol., 11, 327-335.
    • (2001) Curr. Opin. Neurobiol. , vol.11 , pp. 327-335
    • Cull-Candy, S.1    Brickley, S.2    Farrant, M.3
  • 14
    • 10444276589 scopus 로고    scopus 로고
    • Making protein interactions druggable: Targeting PDZ domains
    • Dev, K.K. (2004) Making protein interactions druggable: targeting PDZ domains. Nat. Rev. Drug Discov., 3, 1047-1056.
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 1047-1056
    • Dev, K.K.1
  • 15
    • 0030604722 scopus 로고    scopus 로고
    • Crystal structure of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ
    • Doyle, D.A., Lee, A., Lewis, J., Kim, E., Sheng, M., MacKinnon, R. (1996) Crystal structure of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell, 85, 1067-1076.
    • (1996) Cell , vol.85 , pp. 1067-1076
    • Doyle, D.A.1    Lee, A.2    Lewis, J.3    Kim, E.4    Sheng, M.5    MacKinnon, R.6
  • 16
    • 0032588758 scopus 로고    scopus 로고
    • AlphaCaMKII binding to the C-terminal tail of NMDA receptor subunit NR2A and its modulation by autophosphorylation
    • Gardoni, F., Schrama, L.H., van Dalen, J.J., Gispen, W.H., Cattabeni, F., Di Luca, M. (1999) AlphaCaMKII binding to the C-terminal tail of NMDA receptor subunit NR2A and its modulation by autophosphorylation. FEBS Lett., 456, 394-398.
    • (1999) FEBS Lett. , vol.456 , pp. 394-398
    • Gardoni, F.1    Schrama, L.H.2    van Dalen, J.J.3    Gispen, W.H.4    Cattabeni, F.5    Di Luca, M.6
  • 19
    • 0141682535 scopus 로고    scopus 로고
    • Specific involvement in neuropathic pain of AMPA receptors and adapter proteins for the GluR2 subunit
    • Garry, E.M., Moss, A., Rosie, R., Delaney, A., Mitchell, R., Fleetwood-Walker, S.M. (2003) Specific involvement in neuropathic pain of AMPA receptors and adapter proteins for the GluR2 subunit. Mol. Cell Neurosci., 24, 10-22.
    • (2003) Mol. Cell Neurosci. , vol.24 , pp. 10-22
    • Garry, E.M.1    Moss, A.2    Rosie, R.3    Delaney, A.4    Mitchell, R.5    Fleetwood-Walker, S.M.6
  • 20
    • 0001924058 scopus 로고
    • The organization of biochemically characterized sensory neurons
    • In: Scott, S.A., Ed., Oxford University Press, New York
    • Hunt, S.P. Mantyh, P.W., Priestley, J.V. (1992) The organization of biochemically characterized sensory neurons. In: Sensory neurons, diversity, development, and plasticity, Scott, S.A., Ed., pp. 60-76, Oxford University Press, New York.
    • (1992) Sensory Neurons, Diversity, Development, and Plasticity , pp. 60-76
    • Hunt, S.P.1    Mantyh, P.W.2    Priestley, J.V.3
  • 21
    • 3342924056 scopus 로고    scopus 로고
    • Abnormal motor behavior and vestibular dysfunction in the stargazer mouse mutant
    • Khan, Z., Carey, J., Park, H.J., Lehar, M., Lasker, D., Jinnah, H.A. (2004) Abnormal motor behavior and vestibular dysfunction in the stargazer mouse mutant. Neuroscience, 127, 785-796.
    • (2004) Neuroscience , vol.127 , pp. 785-796
    • Khan, Z.1    Carey, J.2    Park, H.J.3    Lehar, M.4    Lasker, D.5    Jinnah, H.A.6
  • 22
    • 0030200438 scopus 로고    scopus 로고
    • Heteromultimerization and NMDA receptor-clustering activity of chapsyn-110, a member of the PSD-95 family of proteins
    • Kim, E., Cho, K. O., Rothschild, A., Sheng M. (1996) Heteromultimerization and NMDA receptor-clustering activity of chapsyn-110, a member of the PSD-95 family of proteins. Neuron, 17, 103-113.
    • (1996) Neuron , vol.17 , pp. 103-113
    • Kim, E.1    Cho, K.O.2    Rothschild, A.3    Sheng, M.4
  • 23
    • 5044224260 scopus 로고    scopus 로고
    • PDZ domain proteins of synapses
    • Kim, E., Sheng, M. (2004) PDZ domain proteins of synapses. Nat. Rev. Neurosci., 5, 771-781.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 771-781
    • Kim, E.1    Sheng, M.2
  • 24
    • 0032055396 scopus 로고    scopus 로고
    • SynGAP: A synaptic RasGAP that associates with the PSD-95/SAP90 protein family
    • Kim, J.H., Liao, D., Lau, L.F., Huganir, R.L. (1998) SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family. Neuron, 20, 683-91.
    • (1998) Neuron , vol.20 , pp. 683-691
    • Kim, J.H.1    Liao, D.2    Lau, L.F.3    Huganir, R.L.4
  • 27
    • 0029788216 scopus 로고    scopus 로고
    • Interaction of the N-methyl-D-aspartate receptor complex with a novel synapse-associated proteins, SAP102
    • Lau, L. F., Mammer, A., Ehlers, M. D., Kindler, S., Chung, W. J., Garner, C. C., Huganir, R. L. (1996) Interaction of the N-methyl-D-aspartate receptor complex with a novel synapse-associated proteins, SAP102. J. Biol. Chem., 271, 21622-21628.
    • (1996) J. Biol. Chem. , vol.271 , pp. 21622-21628
    • Lau, L.F.1    Mammer, A.2    Ehlers, M.D.3    Kindler, S.4    Chung, W.J.5    Garner, C.C.6    Huganir, R.L.7
  • 28
    • 8544244897 scopus 로고    scopus 로고
    • Postsynaptic density protein-95 regulates NMDA channel gating and surface expression
    • Lin, Y., Skeberdis, V.A., Francesconi, A., Bennett, M.V., Zukin, R.S. (2004) Postsynaptic density protein-95 regulates NMDA channel gating and surface expression. J. Neurosci., 24, 10138-10148.
    • (2004) J. Neurosci. , vol.24 , pp. 10138-10148
    • Lin, Y.1    Skeberdis, V.A.2    Francesconi, A.3    Bennett, M.V.4    Zukin, R.S.5
  • 29
    • 0028096801 scopus 로고
    • Cloning and characterization of hdlg: The human hornolog of the Drosophila discs large tumor suppressor binds to protein 4.1
    • Lue, R.A., Marfatia, S.M., Branton, D., Chishti, A.H. (1994) Cloning and characterization of hdlg: the human hornolog of the Drosophila discs large tumor suppressor binds to protein 4.1. Proc. Natl. Acad. Sci. USA, 91, 9818-9822.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9818-9822
    • Lue, R.A.1    Marfatia, S.M.2    Branton, D.3    Chishti, A.H.4
  • 30
    • 0033232917 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase mRNA upregulation in rat sensory neurons after spinal nerve ligation: Lack of a role in allodynia development
    • Luo, Z.D., Chaplan, S.R., Scott, B.P., Cizkova, D., Calcutt, N.A., Yaksh, T.L. (1999) Neuronal nitric oxide synthase mRNA upregulation in rat sensory neurons after spinal nerve ligation: lack of a role in allodynia development. J. Neurosci., 19, 9201-9208.
    • (1999) J. Neurosci. , vol.19 , pp. 9201-9208
    • Luo, Z.D.1    Chaplan, S.R.2    Scott, B.P.3    Cizkova, D.4    Calcutt, N.A.5    Yaksh, T.L.6
  • 31
    • 0023674299 scopus 로고
    • Microtubule-associated proteins: Their potential role in determining neuronal morphology
    • Matus, A. (1988) Microtubule-associated proteins: their potential role in determining neuronal morphology. Annu. Rev. Neurosci., 11, 29-44.
    • (1988) Annu. Rev. Neurosci. , vol.11 , pp. 29-44
    • Matus, A.1
  • 33
    • 0026726106 scopus 로고
    • Nitric oxide mediates the thermal hyperalgesia produced in a model of neuropathic pain in the rat
    • Meller, S.T., Pechman, P.S., Gebhart, G.F., Maves, T.J. (1992) Nitric oxide mediates the thermal hyperalgesia produced in a model of neuropathic pain in the rat. Neuroscience, 50, 7-10.
    • (1992) Neuroscience , vol.50 , pp. 7-10
    • Meller, S.T.1    Pechman, P.S.2    Gebhart, G.F.3    Maves, T.J.4
  • 35
    • 0028810883 scopus 로고
    • Structure and function of the NMDA receptor channel
    • Mori, H., Mishina, M. (1995) Structure and function of the NMDA receptor channel. Neuropharmacology, 34, 1219-1237.
    • (1995) Neuropharmacology , vol.34 , pp. 1219-1237
    • Mori, H.1    Mishina, M.2
  • 37
    • 0028906288 scopus 로고
    • Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein
    • Muller, B.M., Kistner, U., Veh, R.W., Cases, L.C., Becker, B., Gundelfinger, E.D., Garner, C.C. (1995) Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein. J Neurosci., 15, 2354-2366.
    • (1995) J Neurosci. , vol.15 , pp. 2354-2366
    • Muller, B.M.1    Kistner, U.2    Veh, R.W.3    Cases, L.C.4    Becker, B.5    Gundelfinger, E.D.6    Garner, C.C.7
  • 38
    • 0026437728 scopus 로고
    • Molecular diversity of glutamate receptors and implications for brain function
    • Nakanishi, S. (1992) Molecular diversity of glutamate receptors and implications for brain function. Science, 258, 597-603.
    • (1992) Science , vol.258 , pp. 597-603
    • Nakanishi, S.1
  • 39
    • 0025010056 scopus 로고
    • Stargazer: A new neurological mutant on chromoson 15 in the mouse with prolonged cortical seizures
    • Noebels, J.L., Qiao, X., Bronson, R.T., Spencer, C., Davisson, M.T. (1990) Stargazer: a new neurological mutant on chromoson 15 in the mouse with prolonged cortical seizures. Epilepsy Res., 7, 129-135.
    • (1990) Epilepsy Res. , vol.7 , pp. 129-135
    • Noebels, J.L.1    Qiao, X.2    Bronson, R.T.3    Spencer, C.4    Davisson, M.T.5
  • 40
    • 0035840856 scopus 로고    scopus 로고
    • NMDA receptors as targets for drug action in neuropathic pain
    • Parsons, C.G. (2001) NMDA receptors as targets for drug action in neuropathic pain. Eur. J. Pharmacol., 429, 71-78.
    • (2001) Eur. J. Pharmacol. , vol.429 , pp. 71-78
    • Parsons, C.G.1
  • 41
    • 0031457622 scopus 로고    scopus 로고
    • Signaling through scaffold, anchoring, and adaptor proteins
    • Pawson, T., Scott, J.D. (1997) Signaling through scaffold, anchoring, and adaptor proteins. Science, 278, 2075-2080.
    • (1997) Science , vol.278 , pp. 2075-2080
    • Pawson, T.1    Scott, J.D.2
  • 42
    • 0033562433 scopus 로고    scopus 로고
    • Postsynaptic density-93 interacts with the δ2 glutamate receptor subunits at parallel fiber synapses
    • Roche, K.W., Ly, C.D., Petralia, R.S., Wang,Y.-X., McGee, A.W., Bredt, D.S., Wenthold, R.J. (1999) Postsynaptic density-93 interacts with the δ2 glutamate receptor subunits at parallel fiber synapses. J. Neurosci., 19, 3926-3934.
    • (1999) J. Neurosci. , vol.19 , pp. 3926-3934
    • Roche, K.W.1    Ly, C.D.2    Petralia, R.S.3    Wang, Y.-X.4    McGee, A.W.5    Bredt, D.S.6    Wenthold, R.J.7
  • 44
    • 0000581547 scopus 로고
    • The somatosensory system
    • In: Bjorklund A, Hokfelt T, Swanson LW, Eds, Amsterdam: Elsevier
    • Rustioni, A., Weinberg, R.J. (1989) The somatosensory system. In: Handbook of Chemical Neuroanatomy, Bjorklund A, Hokfelt T, Swanson LW, Eds, pp. 219-321. Amsterdam: Elsevier.
    • (1989) Handbook of Chemical Neuroanatomy , pp. 219-321
    • Rustioni, A.1    Weinberg, R.J.2
  • 46
    • 0033546347 scopus 로고    scopus 로고
    • Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein
    • Sattler, R., Xiong, Z., Lu, W.Y., Hafner, M., MacDonald, J.F., Tymianski, M. (1999) Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science, 284, 1845-1848.
    • (1999) Science , vol.284 , pp. 1845-1848
    • Sattler, R.1    Xiong, Z.2    Lu, W.Y.3    Hafner, M.4    MacDonald, J.F.5    Tymianski, M.6
  • 47
    • 0034657662 scopus 로고    scopus 로고
    • An intramolecular interaction between Src homology 3 domain and guanylate kinase-like domain required for channel clustering by postsynaptic density-95/Sap90
    • Shin, H., Hsueh, Y.-P., Yang, F.-C., Kim, E., Sheng, M. (2000) An intramolecular interaction between Src homology 3 domain and guanylate kinase-like domain required for channel clustering by postsynaptic density-95/Sap90. J. Neurosci., 20, 3580-3587.
    • (2000) J. Neurosci. , vol.20 , pp. 3580-3587
    • Shin, H.1    Hsueh, Y.-P.2    Yang, F.-C.3    Kim, E.4    Sheng, M.5
  • 48
    • 0035708880 scopus 로고    scopus 로고
    • Internalization of ionotropic glutamate receptors in response to mGluR activation
    • Snyder, E.M., Philpot, B.D., Huber, K.M., Dong, X., Fallon, J.R., Bear, M.F. (2001) Internalization of ionotropic glutamate receptors in response to mGluR activation. Nat. Neurosci., 4, 1079-1085.
    • (2001) Nat. Neurosci. , vol.4 , pp. 1079-1085
    • Snyder, E.M.1    Philpot, B.D.2    Huber, K.M.3    Dong, X.4    Fallon, J.R.5    Bear, M.F.6
  • 50
    • 0034128690 scopus 로고    scopus 로고
    • Expression of PSD-95/SAP90 is critical for NMDA receptor-mediated thermal hyperalgesia in the spinal cord
    • Tan, Y.-X., Huang, Y.Z., Mei, L., Johns, R.A. (2000) Expression of PSD-95/SAP90 is critical for NMDA receptor-mediated thermal hyperalgesia in the spinal cord. Neuroscience, 98, 201-206.
    • (2000) Neuroscience , vol.98 , pp. 201-206
    • Tan, Y.-X.1    Huang, Y.Z.2    Mei, L.3    Johns, R.A.4
  • 51
    • 3242751969 scopus 로고    scopus 로고
    • Are synaptic MAGUK proteins involved in chronic pain?
    • Tan, Y.-X., Raja, S.N. (2004) Are synaptic MAGUK proteins involved in chronic pain? Trends Pharmacol. Sci., 25, 397-400.
    • (2004) Trends Pharmacol. Sci. , vol.25 , pp. 397-400
    • Tan, Y.-X.1    Raja, S.N.2
  • 53
    • 0035968929 scopus 로고    scopus 로고
    • Knockdown of PSD-95/SAP90 delays the development of neuropathic pain in rats
    • Tao, F., Tao, Y.-X., Gonzalez, J.A., Fang, M., Mao, P., Johns, R.A. (2001) Knockdown of PSD-95/SAP90 delays the development of neuropathic pain in rats. NeuroReport, 12, 3251-3255.
    • (2001) NeuroReport , vol.12 , pp. 3251-3255
    • Tao, F.1    Tao, Y.-X.2    Gonzalez, J.A.3    Fang, M.4    Mao, P.5    Johns, R.A.6
  • 54
    • 0037475139 scopus 로고    scopus 로고
    • Role of postsynaptic density protein-95 in the maintenance of perpherial nerve injury-induced neuropathic pain in rats
    • Tao, F. Tao, Y.-X., Mao, P., Johns, R.A. (2003) Role of postsynaptic density protein-95 in the maintenance of perpherial nerve injury-induced neuropathic pain in rats. Neuroscience, 117, 731-739.
    • (2003) Neuroscience , vol.117 , pp. 731-739
    • Tao, F.1    Tao, Y.-X.2    Mao, P.3    Johns, R.A.4
  • 55
    • 0033582266 scopus 로고    scopus 로고
    • PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A
    • Tezuka, T., Umemori, H., Akiyama, T., Nakanishi, S., Yamamoto, T. (1999) PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A. Proc. Natl. Acad. Sci. USA, 96, 435-40.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 435-440
    • Tezuka, T.1    Umemori, H.2    Akiyama, T.3    Nakanishi, S.4    Yamamoto, T.5
  • 56
    • 0034645726 scopus 로고    scopus 로고
    • Solution structure and backbone dynamics of the second PDZ domain of PSD-95
    • Tochio, H., Hung, F., Li, M., Bredt, D.S., Zhang M. (2000) Solution structure and backbone dynamics of the second PDZ domain of PSD-95. J. Mol. Biol., 295, 225-237.
    • (2000) J. Mol. Biol. , vol.295 , pp. 225-237
    • Tochio, H.1    Hung, F.2    Li, M.3    Bredt, D.S.4    Zhang, M.5
  • 57
    • 0034721943 scopus 로고    scopus 로고
    • Formation of nNOS/PSD-95 PDZ dimer requires a preformed beta-finger structure from die nNOS PDZ domain
    • Tochio, H., Mok, Y.K., Zhang, Q., Kan, H.M., Bredt, D.S., Zhang, M. (2000) Formation of nNOS/PSD-95 PDZ dimer requires a preformed beta-finger structure from die nNOS PDZ domain. J. Mol. Biol., 303, 359-370.
    • (2000) J. Mol. Biol. , vol.303 , pp. 359-370
    • Tochio, H.1    Mok, Y.K.2    Zhang, Q.3    Kan, H.M.4    Bredt, D.S.5    Zhang, M.6
  • 60
    • 1542320274 scopus 로고    scopus 로고
    • Involvement of NMDA receptors/nitric oxide signaling pathway in platelet-activating factor-induced neurotoxicity in mouse neuronal cultures
    • Xu, Y., Tao, Y.-X. (2004) Involvement of NMDA receptors/nitric oxide signaling pathway in platelet-activating factor-induced neurotoxicity in mouse neuronal cultures. NeuroReport, 15, 263-266.
    • (2004) NeuroReport , vol.15 , pp. 263-266
    • Xu, Y.1    Tao, Y.-X.2
  • 61
    • 3543065264 scopus 로고    scopus 로고
    • Targeted disruption of PSD-93 gene reduces platelet-activating factor-induced neurotoxicity in cultured cortical neurons
    • Xu, Y., Zhang, B., Hua, Z., Johns, R.A., Bredt, D.S., Tao, Y.-X. (2004) Targeted disruption of PSD-93 gene reduces platelet-activating factor-induced neurotoxicity in cultured cortical neurons. Exp. Neurol., 189, 16-24.
    • (2004) Exp. Neurol. , vol.189 , pp. 16-24
    • Xu, Y.1    Zhang, B.2    Hua, Z.3    Johns, R.A.4    Bredt, D.S.5    Tao, Y.-X.6
  • 62
    • 0032790229 scopus 로고    scopus 로고
    • Subunit- and site-specific pharmacology of the NMDA receptor channel
    • Yamakura, T., Shimoji, K. (1999) Subunit- and site-specific pharmacology of the NMDA receptor channel. Prog. Neurobiol., 59, 279-298.
    • (1999) Prog. Neurobiol. , vol.59 , pp. 279-298
    • Yamakura, T.1    Shimoji, K.2
  • 63
    • 0029034414 scopus 로고
    • Role of nitric oxide in the development of thermal hyperesthesia induced by sciatic nerve constriction injury in the rat
    • Yamamoto, T., Shimoyama, N. (1995) Role of nitric oxide in the development of thermal hyperesthesia induced by sciatic nerve constriction injury in the rat. Anesthesiology, 82, 1266-1273.
    • (1995) Anesthesiology , vol.82 , pp. 1266-1273
    • Yamamoto, T.1    Shimoyama, N.2
  • 64
    • 0009650312 scopus 로고    scopus 로고
    • Nitric oxide mediates behavioral signs of neuropathic pain in an experimental rat model
    • Yoon, Y.W., Sung, B., Chung, J.M. (1998) Nitric oxide mediates behavioral signs of neuropathic pain in an experimental rat model. NeuroReport, 9, 367-372.
    • (1998) NeuroReport , vol.9 , pp. 367-372
    • Yoon, Y.W.1    Sung, B.2    Chung, J.M.3
  • 65
    • 0242383919 scopus 로고    scopus 로고
    • Effect of knock down of spinal cord PSD-93/chapsin-110 on persistent pain induced by complete Freund's adjuvant and peripheral nerve injury
    • Zhang, B., Tao, F., Liaw, W.J., Bredt, D.S., Johns, R.A., Tao, Y.-X. (2003) Effect of knock down of spinal cord PSD-93/chapsin-110 on persistent pain induced by complete Freund's adjuvant and peripheral nerve injury. Pain, 106, 187-196.
    • (2003) Pain , vol.106 , pp. 187-196
    • Zhang, B.1    Tao, F.2    Liaw, W.J.3    Bredt, D.S.4    Johns, R.A.5    Tao, Y.-X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.