The role of pharmacogenetics in cancer therapeutics

British Journal of Clinical Pharmacology

Volumn 62, Issue 1, 2006, Pages 35-46

  Yong, Wei Peng ^a   Innocenti, Federico ^a   Ratain, Mark J ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Cancer therapeutics; Chemotherapy; Pharmacogenetics; Polymorphisms

Indexed keywords

4 HYDROXYTAMOXIFEN; 5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); 7 ETHYL 10 HYDROXYCAMPTOTHECIN; ANTIMETABOLITE; ANTINEOPLASTIC AGENT; AZATHIOPRINE; CAPECITABINE; CYTOCHROME P450 2D6; DIHYDROPYRIMIDINE DEHYDROGENASE; DRUG METABOLIZING ENZYME; ENDOXIFEN; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; ETOPOSIDE; FLOXURIDINE; FLUOROURACIL; FOLIC ACID; GEFITINIB; GLUCURONOSYLTRANSFERASE; IRINOTECAN; MERCAPTOPURINE; METHOTREXATE; PROTEIN TYROSINE KINASE INHIBITOR; RALTITREXED; TAMOXIFEN; THIOPURINE METHYLTRANSFERASE; THYMIDYLATE SYNTHASE; TIOGUANINE; UNCLASSIFIED DRUG;

ACUTE LYMPHOCYTIC LEUKEMIA; BONE MARROW TRANSPLANTATION; BRAIN METASTASIS; BREAST CANCER; CANCER; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER RESISTANCE; CANCER SURVIVAL; CHILDHOOD CANCER; CLINICAL TRIAL; COLORECTAL CANCER; COST CONTROL; COST EFFECTIVENESS ANALYSIS; DIARRHEA; DISEASE FREE SURVIVAL; DRUG BLOOD LEVEL; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG ERUPTION; DRUG FATALITY; DRUG INACTIVATION; DRUG METABOLISM; DRUG OVERDOSE; DRUG POTENCY; DRUG RESEARCH; DRUG SAFETY; DRUG TARGETING; DRUG TOLERABILITY; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GRAFT VERSUS HOST REACTION; HUMAN; HYPERBILIRUBINEMIA; LEUKEMOGENESIS; LUNG NON SMALL CELL CANCER; MUCOSA INFLAMMATION; MYELOID LEUKEMIA; NEUROLOGIC DISEASE; NEUTROPENIA; OVARY CANCER; PHARMACOGENETICS; PRIORITY JOURNAL; RACE DIFFERENCE; RADIATION CARCINOGENESIS; REVIEW; SKIN TOXICITY; SOMATIC MUTATION; TREATMENT OUTCOME; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT;

ANTINEOPLASTIC AGENTS; DRUG DESIGN; DRUG INTERACTIONS; ENZYMES; FORECASTING; GERM-LINE MUTATION; HUMANS; NEOPLASMS; PHARMACOGENETICS; POLYMORPHISM, GENETIC; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 33746872914     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2006.02591.x     Document Type: Review

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