메뉴 건너뛰기




Volumn 312, Issue 14, 2006, Pages 2654-2659

The Rad53 signal transduction pathway: Replication fork stabilization, DNA repair, and adaptation

Author keywords

Cell cycle; Checkpoints; Recombination; Replication

Indexed keywords

CHECKPOINT KINASE 2; HYDROXYUREA;

EID: 33746816108     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2006.06.012     Document Type: Review
Times cited : (98)

References (41)
  • 1
    • 0036531901 scopus 로고    scopus 로고
    • A unified view of the DNA-damage checkpoint
    • Melo J., and Toczyski D. A unified view of the DNA-damage checkpoint. Curr. Opin. Cell Biol. 14 (2002) 237-245
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 237-245
    • Melo, J.1    Toczyski, D.2
  • 2
    • 27544445683 scopus 로고    scopus 로고
    • The DNA damage response during DNA replication
    • Branzei D., and Foiani M. The DNA damage response during DNA replication. Curr. Opin. Cell Biol. 17 (2005) 568-575
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 568-575
    • Branzei, D.1    Foiani, M.2
  • 3
    • 0037178722 scopus 로고    scopus 로고
    • Maintenance of genome stability in Saccharomyces cerevisiae
    • Kolodner R.D., Putnam C.D., and Myung K. Maintenance of genome stability in Saccharomyces cerevisiae. Science 297 (2002) 552-557
    • (2002) Science , vol.297 , pp. 552-557
    • Kolodner, R.D.1    Putnam, C.D.2    Myung, K.3
  • 4
    • 30144439370 scopus 로고    scopus 로고
    • Common fragile sites
    • Glover T.W. Common fragile sites. Cancer Lett. 232 (2006) 4-12
    • (2006) Cancer Lett. , vol.232 , pp. 4-12
    • Glover, T.W.1
  • 5
    • 0035105240 scopus 로고    scopus 로고
    • Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest
    • Pellicioli A., Lee S.E., Lucca C., Foiani M., and Haber J.E. Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest. Mol. Cell 7 (2001) 293-300
    • (2001) Mol. Cell , vol.7 , pp. 293-300
    • Pellicioli, A.1    Lee, S.E.2    Lucca, C.3    Foiani, M.4    Haber, J.E.5
  • 6
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • Zou L., and Elledge S.J. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300 (2003) 1542-1548
    • (2003) Science , vol.300 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2
  • 7
    • 0033575659 scopus 로고    scopus 로고
    • Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1- and Rad53-dependent checkpoint in budding yeast
    • Neecke H., Lucchini G., and Longhese M.P. Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1- and Rad53-dependent checkpoint in budding yeast. EMBO J. 18 (1999) 4485-4497
    • (1999) EMBO J. , vol.18 , pp. 4485-4497
    • Neecke, H.1    Lucchini, G.2    Longhese, M.P.3
  • 8
    • 1542320702 scopus 로고    scopus 로고
    • Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint
    • Giannattasio M., Lazzaro F., Longhese M.P., Plevani P., and Muzi-Falconi M. Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint. EMBO J. 23 (2004) 429-438
    • (2004) EMBO J. , vol.23 , pp. 429-438
    • Giannattasio, M.1    Lazzaro, F.2    Longhese, M.P.3    Plevani, P.4    Muzi-Falconi, M.5
  • 9
    • 0030793718 scopus 로고    scopus 로고
    • Rfc5, a replication factor C component, is required for regulation of Rad53 protein kinase in the yeast checkpoint pathway
    • Sugimoto K., Ando S., Shimomura T., and Matsumoto K. Rfc5, a replication factor C component, is required for regulation of Rad53 protein kinase in the yeast checkpoint pathway. Mol. Cell. Biol. 17 (1997) 5905-5914
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5905-5914
    • Sugimoto, K.1    Ando, S.2    Shimomura, T.3    Matsumoto, K.4
  • 10
    • 0038730929 scopus 로고    scopus 로고
    • A central role for DNA replication forks in checkpoint activation and response
    • Tercero J.A., Longhese M.P., and Diffley J.F. A central role for DNA replication forks in checkpoint activation and response. Mol. Cell 11 (2003) 1323-1336
    • (2003) Mol. Cell , vol.11 , pp. 1323-1336
    • Tercero, J.A.1    Longhese, M.P.2    Diffley, J.F.3
  • 11
    • 0037115462 scopus 로고    scopus 로고
    • ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase
    • Shimada K., Pasero P., and Gasser S.M. ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase. Genes Dev. 16 (2002) 3236-3252
    • (2002) Genes Dev. , vol.16 , pp. 3236-3252
    • Shimada, K.1    Pasero, P.2    Gasser, S.M.3
  • 12
    • 11344268431 scopus 로고    scopus 로고
    • Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells
    • Cotta-Ramusino C., Fachinetti D., Lucca C., Doksani Y., Lopes M., Sogo J., and Foiani M. Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells. Mol. Cell 17 (2005) 153-159
    • (2005) Mol. Cell , vol.17 , pp. 153-159
    • Cotta-Ramusino, C.1    Fachinetti, D.2    Lucca, C.3    Doksani, Y.4    Lopes, M.5    Sogo, J.6    Foiani, M.7
  • 13
    • 0032493889 scopus 로고    scopus 로고
    • Saccharomyces Ku70, Mre11/Rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage
    • Lee S.E., Moore J.K., Holmes A., Umezu K., Kolodner R.D., and Haber J.E. Saccharomyces Ku70, Mre11/Rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell 94 (1998) 399-409
    • (1998) Cell , vol.94 , pp. 399-409
    • Lee, S.E.1    Moore, J.K.2    Holmes, A.3    Umezu, K.4    Kolodner, R.D.5    Haber, J.E.6
  • 15
    • 0032079366 scopus 로고    scopus 로고
    • RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation
    • de la Torre-Ruiz M.A., Green C.M., and Lowndes N.F. RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation. EMBO J. 17 (1998) 2687-2698
    • (1998) EMBO J. , vol.17 , pp. 2687-2698
    • de la Torre-Ruiz, M.A.1    Green, C.M.2    Lowndes, N.F.3
  • 16
    • 0037418195 scopus 로고    scopus 로고
    • Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint
    • Majka J., and Burgers P.M. Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 2249-2254
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 2249-2254
    • Majka, J.1    Burgers, P.M.2
  • 17
    • 0035498938 scopus 로고    scopus 로고
    • Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
    • Melo J.A., Cohen J., and Toczyski D.P. Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev. 15 (2001) 2809-2821
    • (2001) Genes Dev. , vol.15 , pp. 2809-2821
    • Melo, J.A.1    Cohen, J.2    Toczyski, D.P.3
  • 18
    • 0035955398 scopus 로고    scopus 로고
    • Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms
    • Kondo T., Wakayama T., Naiki T., Matsumoto K., and Sugimoto K. Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms. Science 294 (2001) 867-870
    • (2001) Science , vol.294 , pp. 867-870
    • Kondo, T.1    Wakayama, T.2    Naiki, T.3    Matsumoto, K.4    Sugimoto, K.5
  • 19
    • 0037080675 scopus 로고    scopus 로고
    • Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin
    • Zou L., Cortez D., and Elledge S.J. Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin. Genes Dev. 16 (2002) 198-208
    • (2002) Genes Dev. , vol.16 , pp. 198-208
    • Zou, L.1    Cortez, D.2    Elledge, S.J.3
  • 20
    • 24944575222 scopus 로고    scopus 로고
    • Signal transduction: how Rad53 kinase is activated
    • Pellicioli A., and Foiani M. Signal transduction: how Rad53 kinase is activated. Curr. Biol. 15 (2005) R769-R771
    • (2005) Curr. Biol. , vol.15
    • Pellicioli, A.1    Foiani, M.2
  • 21
    • 0034881760 scopus 로고    scopus 로고
    • Budding yeast Rad9 is an ATP-dependent Rad53 activating machine
    • Gilbert C.S., Green C.M., and Lowndes N.F. Budding yeast Rad9 is an ATP-dependent Rad53 activating machine. Mol. Cell 8 (2001) 129-136
    • (2001) Mol. Cell , vol.8 , pp. 129-136
    • Gilbert, C.S.1    Green, C.M.2    Lowndes, N.F.3
  • 22
    • 0033527787 scopus 로고    scopus 로고
    • Control of the DNA damage checkpoint by Chk1 and Rad53 protein kinases through distinct mechanisms
    • Sanchez Y., Bachant J., Wang H., Hu F., Liu D., Tetzlaff M., and Elledge S.J. Control of the DNA damage checkpoint by Chk1 and Rad53 protein kinases through distinct mechanisms. Science 286 (1999) 1166-1171
    • (1999) Science , vol.286 , pp. 1166-1171
    • Sanchez, Y.1    Bachant, J.2    Wang, H.3    Hu, F.4    Liu, D.5    Tetzlaff, M.6    Elledge, S.J.7
  • 23
    • 25444466892 scopus 로고    scopus 로고
    • Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9
    • Wysocki R., Javaheri A., Allard S., Sha F., Cote J., and Kron S.J. Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9. Mol. Cell. Biol. 25 (2005) 8430-8443
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 8430-8443
    • Wysocki, R.1    Javaheri, A.2    Allard, S.3    Sha, F.4    Cote, J.5    Kron, S.J.6
  • 24
    • 15444373985 scopus 로고    scopus 로고
    • The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1
    • Giannattasio M., Lazzaro F., Plevani P., and Muzi-Falconi M. The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1. J. Biol. Chem. 280 (2005) 9879-9886
    • (2005) J. Biol. Chem. , vol.280 , pp. 9879-9886
    • Giannattasio, M.1    Lazzaro, F.2    Plevani, P.3    Muzi-Falconi, M.4
  • 25
    • 0029808466 scopus 로고    scopus 로고
    • Cell cycle checkpoints: preventing an identity crisis
    • Elledge S.J. Cell cycle checkpoints: preventing an identity crisis. Science 274 (1996) 1664-1672
    • (1996) Science , vol.274 , pp. 1664-1672
    • Elledge, S.J.1
  • 27
    • 0037133566 scopus 로고    scopus 로고
    • The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1
    • Zhao X., and Rothstein R. The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 3746-3751
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 3746-3751
    • Zhao, X.1    Rothstein, R.2
  • 28
    • 0032530824 scopus 로고    scopus 로고
    • Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway
    • Desany B.A., Alcasabas A.A., Bachant J.B., and Elledge S.J. Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway. Genes Dev. 12 (1998) 2956-2970
    • (1998) Genes Dev. , vol.12 , pp. 2956-2970
    • Desany, B.A.1    Alcasabas, A.A.2    Bachant, J.B.3    Elledge, S.J.4
  • 29
    • 29544437558 scopus 로고    scopus 로고
    • Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions
    • Lopes M., Foiani M., and Sogo J.M. Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions. Mol. Cell 21 (2006) 15-27
    • (2006) Mol. Cell , vol.21 , pp. 15-27
    • Lopes, M.1    Foiani, M.2    Sogo, J.M.3
  • 30
    • 33646122683 scopus 로고    scopus 로고
    • ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks
    • Trenz K., Smith E., Smith S., and Costanzo V. ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks. EMBO J. 25 (2006) 1764-1774
    • (2006) EMBO J. , vol.25 , pp. 1764-1774
    • Trenz, K.1    Smith, E.2    Smith, S.3    Costanzo, V.4
  • 31
    • 33644616440 scopus 로고    scopus 로고
    • The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae
    • Sabbioneda S., Minesinger B.K., Giannattasio M., Plevani P., Muzi-Falconi M., and Jinks-Robertson S. The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae. J. Biol. Chem. 280 (2005) 38657-38665
    • (2005) J. Biol. Chem. , vol.280 , pp. 38657-38665
    • Sabbioneda, S.1    Minesinger, B.K.2    Giannattasio, M.3    Plevani, P.4    Muzi-Falconi, M.5    Jinks-Robertson, S.6
  • 32
    • 32044451333 scopus 로고    scopus 로고
    • Regulation of gross chromosomal rearrangements by ubiquitin and SUMO ligases in Saccharomyces cerevisiae
    • Motegi A., Kuntz K., Majeed A., Smith S., and Myung K. Regulation of gross chromosomal rearrangements by ubiquitin and SUMO ligases in Saccharomyces cerevisiae. Mol. Cell. Biol. 26 (2006) 1424-1433
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 1424-1433
    • Motegi, A.1    Kuntz, K.2    Majeed, A.3    Smith, S.4    Myung, K.5
  • 33
    • 0029772319 scopus 로고    scopus 로고
    • Semidominant mutations in the yeast Rad51 protein and their relationships with the Srs2 helicase
    • Chanet R., Heude M., Adjiri A., Maloisel L., and Fabre F. Semidominant mutations in the yeast Rad51 protein and their relationships with the Srs2 helicase. Mol. Cell. Biol. 16 (1996) 4782-4789
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4782-4789
    • Chanet, R.1    Heude, M.2    Adjiri, A.3    Maloisel, L.4    Fabre, F.5
  • 34
    • 20744454423 scopus 로고    scopus 로고
    • Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation
    • Chiolo I., Carotenuto W., Maffioletti G., Petrini J.H., Foiani M., and Liberi G. Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation. Mol. Cell. Biol. 25 (2005) 5738-5751
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 5738-5751
    • Chiolo, I.1    Carotenuto, W.2    Maffioletti, G.3    Petrini, J.H.4    Foiani, M.5    Liberi, G.6
  • 37
    • 33646106590 scopus 로고    scopus 로고
    • gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes
    • Stucki M., and Jackson S.P. gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes. DNA Rep. (Amst) (2006)
    • (2006) DNA Rep. (Amst)
    • Stucki, M.1    Jackson, S.P.2
  • 38
    • 33645008019 scopus 로고    scopus 로고
    • ATR homolog Mec1 controls association of DNA polymerase zeta-Rev1 complex with regions near a double-strand break
    • Hirano Y., and Sugimoto K. ATR homolog Mec1 controls association of DNA polymerase zeta-Rev1 complex with regions near a double-strand break. Curr. Biol. 16 (2006) 586-590
    • (2006) Curr. Biol. , vol.16 , pp. 586-590
    • Hirano, Y.1    Sugimoto, K.2
  • 39
    • 0027421043 scopus 로고
    • Loss of a yeast telomere: arrest, recovery, and chromosome loss
    • Sandell L.L., and Zakian V.A. Loss of a yeast telomere: arrest, recovery, and chromosome loss. Cell 75 (1993) 729-739
    • (1993) Cell , vol.75 , pp. 729-739
    • Sandell, L.L.1    Zakian, V.A.2
  • 40
    • 2542459341 scopus 로고    scopus 로고
    • Adaptation of a DNA replication checkpoint response depends upon inactivation of claspin by the Polo-like kinase
    • Yoo H.Y., Kumagai A., Shevchenko A., Shevchenko A., and Dunphy W.G. Adaptation of a DNA replication checkpoint response depends upon inactivation of claspin by the Polo-like kinase. Cell 117 (2004) 575-588
    • (2004) Cell , vol.117 , pp. 575-588
    • Yoo, H.Y.1    Kumagai, A.2    Shevchenko, A.3    Shevchenko, A.4    Dunphy, W.G.5
  • 41
    • 0344643062 scopus 로고    scopus 로고
    • PP2C phosphatases Ptc2 and Ptc3 are required for DNA checkpoint inactivation after a double-strand break
    • Leroy C., Lee S.E., Vaze M.B., Ochsenbien F., Guerois R., Haber J.E., and Marsolier-Kergoat M.C. PP2C phosphatases Ptc2 and Ptc3 are required for DNA checkpoint inactivation after a double-strand break. Mol. Cell 11 (2003) 827-835
    • (2003) Mol. Cell , vol.11 , pp. 827-835
    • Leroy, C.1    Lee, S.E.2    Vaze, M.B.3    Ochsenbien, F.4    Guerois, R.5    Haber, J.E.6    Marsolier-Kergoat, M.C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.