Conjugation to Nedd8 instigates ubiquitylation and down-regulation of activated receptor tyrosine kinases

Journal of Biological Chemistry

Volumn 281, Issue 31, 2006, Pages 21640-21651

  Oved, Shlomo ^a   Mosesson, Yaron ^a   Zwang, Yaara ^a   Santonico, Elena ^b   Shtiegman, Keren ^a   Marmor, Mina D ^a   Kochupurakkal, Bose S ^a   Katz, Menachem ^a   Lavi, Sara ^a   Cesareni, Gianni ^b   Yarden, Yosef ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; ENZYME KINETICS; GROWTH KINETICS;

EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR); KINASES; NEDDYLATION; TYROSINE;

ENZYMES;

CBL PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; NEDD8 PROTEIN; TYROSINE KINASE RECEPTOR;

ANIMAL CELL; ARTICLE; COATED VESICLE; CONTROLLED STUDY; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN MODIFICATION; UBIQUITINATION;

ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; DOWN-REGULATION; HELA CELLS; HUMANS; LYSOSOMES; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-CBL; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS;

EID: 33746797288     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M513034200     Document Type: Article

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