Ligand-independent degradation of epidermal growth factor receptor involves receptor ubiquitylation and Hgs, an adaptor whose ubiquitin-interacting motif targets ubiquitylation by Nedd4

Traffic

Volumn 3, Issue 10, 2002, Pages 740-751

  Katz, Menachem ^a   Shtiegman, Keren ^a   Tal Or, Pazit ^a   Yakir, Liat ^a   Mosesson, Yaron ^a   Harari, Daniel ^a   Machluf, Yossi ^a   Asao, Hironobu ^a   Jovin, Thomas ^a   Sugamura, Kazuo ^a   Yarden, Yosef ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Endocytosis; Epidermal growth factor; Hgs Hrs; Nedd4; Signal transduction; Tyrosine kinase; Ubiquitin

Indexed keywords

ADAPTOR PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; LIGAND; PROTEIN HGS; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE NEDD4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL BUDDING; CHEMICAL MODIFICATION; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; INTRACELLULAR TRANSPORT; LYSOSOME; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN TARGETING; SEQUENCE HOMOLOGY;

AMINO ACID MOTIFS; ANIMALS; CHO CELLS; CRICETINAE; CYTOPLASM; HYDROLYSIS; LIGANDS; PHOSPHOPROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; UBIQUITIN;

EID: 18544383164     PISSN: 13989219     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0854.2002.31006.x     Document Type: Article

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