Dietary apigenin suppresses IgE and inflammatory cytokines production in C57BL/6N mice

Journal of Agricultural and Food Chemistry

Volumn 54, Issue 14, 2006, Pages 5203-5207

  Yano, Satomi ^a   Umeda, Daisuke ^a   Maeda, Norihide ^a   Fujimura, Yoshinori ^a   Yamada, Koji ^a   Tachibana, Hirofumi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Apigenin; C57BL 6N mice; IgE; RANTES; sTNFRI

Indexed keywords

APIGENIN; CYTOKINE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MESSENGER RNA;

ANIMAL; ARTICLE; BLOOD; C57BL MOUSE; CHEMISTRY; CYTOLOGY; DIET; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; IMMUNITY; LYMPHOCYTE; MALE; MOUSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN;

ANIMALS; APIGENIN; CYTOKINES; DIET; GENE EXPRESSION REGULATION; IMMUNITY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LYMPHOCYTES; MALE; MICE; MICE, INBRED C57BL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPLEEN;

EID: 33746560719     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf0607361     Document Type: Article

References (37)

1. Avila, M. A.; Velasco, J. A.; Cansado, J.; Notario, V. Quercetin mediates the down-regulation of mutant p53 in the human breast cancer cell line MDA-MB468. Cancer Res. 1994, 54, 2424-2428.
2. Gerritsen, M. E.; Carley, W. W.; Ranges, G. E.; Shen, C. P.; Phan, S. A.; Ligon, G. F.; Perry, C. A. Flavonoids inhibit cytokine-induced endothelial cell adhesion protein gene expression. Am. J. Pathol. 1995, 147, 278-292.
3. Piantelli, M.; Rossi, C.; Iezzi, M.; La Sorda, R.; Iacobelli, S.; Alberti, S.; Natali, P. G. Flavonoids inhibit melanoma lung metastasis by impairing tumor cells endothelium interactions. J. Cell Physiol. 2006, 207, 23-29.
4. Middleton, E. J.; Kandaswami, C. Effects of flavonoids on immune and inflammatory cell functions. Biochem. Pharmacol. 1992, 43, 1167-1179.
5. Matern, U.; Heller, W.; Himmelspach, K. Conformational changes of apigenin 7-O-(6-O-malonylglucoside), a vacuolar pigment from parsley, with solvent composition and protein concentration. Eur. J. Biochem. 1983, 133, 439-448.
6. Fernandez-de-Simon, B.; Perez-Ilzarbe, J.; Hernandez, T.; Gomez-Cordoves, C.; Estrella, I. Importance of phenolic compounds for the characterization of fruit juices. J. Agric. Food Chem. 1992, 40, 1531-1535.
7. Engelhardt, U. H.; Finger, A.; Kuhr, S. Determination of flavones C-glycosides in tea. Z. Lebensm, Unters. Forsch. 1993, 197, 239-244.
8. Peryt, B.; Szymczyk, T.; Lesca, P. Mechanism of antimutagenicity of wheat sprout extracts. Mutat. Res. 1992, 269, 201-215.
9. Yano, S.; Tachibana, H.; Yamada, K. Flavones suppress the expression of the high-affinity IgE receptor FcεRI in human basophilic KU812 cells. J. Agric. Food Chem. 2005, 53, 1812-1817.
10. Hirano, T.; Higa, S.; Arimitsu, J.; Naka, T.; Ogata, A.; Shima, Y.; Fujimoto, M.; Yamadori, T.; Ohkawara, T.; Kuwabara, Y.; Kawai, M.; Matsuda, H.; Yoshikawa, M.; Maezaki, N.; Tanaka, T.; Kawase, I.; Tanaka, T. Luteolin, a flavonoid, inhibits AP-1 activation by basophils. Biochem. Biophys. Res. Commun. 2006, 340, 1-7.
11. Alfaro-Bustamante, F.; Ramirez-Flores, G.; Gonzalez-Mendoza, A.; Islas-Rodriguez, A.; Fafutis-Morris, M. Effect of phorbol myristate acetate (PMA) and ionophore A23187 on interleukin-2 levels and proliferation of activated T lymphocytes from patients with lepromatous leprosy. Int. J. Lepr. Other Mycobact. Dis. 1997, 65, 73-79.
12. H1 clones. J. Immunol. 1987, 138, 3688-3694.
13. Mosmann, T. R.; Coffman, R. L. Heterogeneity of cytokine secretion patterns and functions of helper T cells. Adv. Immunol. 1988, 46, 111-147.
14. Conti, P.; Barbacane, R. C.; Reale, M. Chemokines in inflammatory states. Allergy Asthma Proc. 1999, 20, 205-208.
15. Gangur, V.; Oppenheim, J. J. Are chemokines essential or secondary participants in allergic responses? Ann. Allergy, Asthma, Immunol. 2000, 84, 569-581.
16. Pritts, E. A.; Zhao, D.; Ricke, E.; Waite, L.; Taylor, R. N. PPAR-γ decreases endometrial stromal cell transcription and translation of RANTES in vitro. J. Clin. Endocrinol. Metab. 2002, 87, 1841-1844.
17. Liang, Y. C.; Tsai, S. H.; Tsai, D. C.; Lin-Shiau, S. Y.; Lin, J. K. Suppression of inducible cyclooxygenase and nitric oxide synthase through activation of peroxisome proliferator-activated receptor-γ by flavonoids in mouse macrophages. FEBS Lett. 2001, 496, 12-18.
18. Miyazaki, Y.; Tachibana, H.; Yamada, K. Inhibitory effect of peroxisome proliferator-activated receptor-γ ligands on the expression of IgE heavy chain germline transcripts in the human B cell line DND39. Biochem. Biophys. Res. Commun. 2002, 295, 547-552.
19. Steinshamn, S.; Brekke, O. L.; Waage, A. Soluble tumor necrosis factor receptors, tumor necrosis factor and interleukin-6 in serum in granulocytopenic patients with fever. Br. J. Haematol. 1995, 89, 719-724.
20. Spengler, U.; Zachoval, R.; Gallati, H.; Jung, M. C.; Hoffmann, R.; Riethmuller, G.; Pape, G. Serum levels and in situ expression of TNF-alpha and TNF-alpha binding proteins in inflammatory liver diseases. Cytokine 1996, 8, 864-872.
21. Corti, A.; Merli, S.; Bagnasco, L.; D'Ambrosio, F.; Marino, M.; Cassani, G. Identification of two forms (31-33 and 48 kD) of the urinary soluble p55 tumor necrosis factor receptor that are differentially N- and O-glycosylated. J. Interferon Cytokine Res. 1995, 15, 143-152.
22. Nophar, Y.; Kemper, O.; Brakebusch, C.; Englemann, H.; Zwang, R.; Aderka, D.; Holtmann, H.; Wallach, D. Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor. EMBO J. 1990, 9, 3269-3278.
23. Van Zee, K. J.; Kohno, T.; Fischer, E.; Rock, C. S.; Moldawer, L. L.; Lowry, S. F. Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo. Proc. Natl. Acad Sci. U.S.A. 1992, 89, 4845-4849.
24. Spinas, G. A.; Keller, U.; Brockhaus, M. Release of soluble receptors for tumor necrosis factor (TNF) in relation to circulating TNF during experimental endotoxinemia. J. Clin. Invest. 1992, 70, 533-536.
25. Andus, T.; Gross, V.; Holstege, A.; Ott, M.; Weber, M.; David, M.; Gallati, H.; Gerok, W.; Scholmerich, J. High concentrations of soluble tumor necrosis factor receptors in ascites. Hepatology 1992, 16, 749-755.
26. Gardiner, K. R.; Halliday, M. I.; Barclay, G. R.; Milne, L.; Brown, D.; Stephens, S.; Maxwell, R. J.; Rowlands, B. J. Significance of systemic endotoxaemia in inflammatory bowel disease. Gut 1995, 36, 897-901.
27. Hadziselimovic, F.; Emmons, L. R.; Gallati, H. Soluble tumor necrosis factor receptors p55 and p75 in the urine monitor disease activity and the efficacy of treatment of inflammatory bowel disease. Gut 1995, 37, 260-263.
28. Heath, H.; Qin, S.; Rao, P.; Wu, L.; LaRosa, G.; Kassam, N.; Ponath, P. D.; Mackay, C. R. Chemokine receptor usage by human eosinophils: The importance of CCR3 demonstrated using an antagonistic monoclonal antibody. J. Clin. Invest. 1997, 99, 1178-184.
29. Manach, C.; Scalbert, A.; Morand, C.; Rémésy, C.; Jiménez, L. Polyphenols: Food sources and bioavailability. Am. J. Clin. Nutr. 2004, 79, 727-747.
30. Rechner, A. R.; Kuhnle, G.; Bremner, P.; Hubbard, G. P.; Moore, K. P.; Rice-Evans, C. The metabolic fate of dietary polyphenols in humans. Free Radical Biol. Med. 2002, 33, 220-235.
31. Rechner, A. R.; Smith, M. A.; Kuhnle, G.; Gibson, G. R.; Debnam, E. S.; Srai, S. K. S.; Moore, K. P.; Rice-Evans, C. Colonie fermentation of dietary polyphenols: influence of structure on microbial fermentation products. Free Radical Biol. Med. 2004, 36, 212-225.
32. Scalbert, A.; Morand, C.; Manach, C.; Rémésy, C. Absorption and metabolism of polyphenols in the gut and impact on health. Biomed. Pharmacother. 2002, 56, 276-282.
33. Justesen, U.; Knuthsen, P.; Leth, T. Quantitative analysis of flavonols, flavones, and flavanones in fruits, vegetables and beverages by high-performance liquid chromatography with photodiode array and mass spectrometric detection. J. Chromatogr. 1998, 799, 101-110.
34. Miean, K. H.; Mohamed, S. Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants. J. Agric. Food Chem. 2001, 49, 3106-3112.
35. Svehlikova, V.; Bennett, R. N.; Mellon, F. A.; Needs, P. W.; Piacente, S.; Kroon, P. A.; Bao, Y. Isolation, identification and stability of acylated derivatives of apigenin 7-O-glucoside from chamomile (Chamomilla recutita [L.] Rauschert). Phytochemistry 2004, 65, 2323-2332.
36. Meyer, H.; Bolarinwa, A.; Wolfram, G.; Linseisen, J. Bioavailability of apigenin from apiin-rich parsley in humans. Ann. Nutr. Metab. 2006, 50, 167-172.
37. Formica, J. V.; Regelson, W. Review of the biology of quercetin and related bioflavonoids. Food Chem. Toxicol. 1995, 12, 1061-1080.