Suppression of inducible cyclooxygenase and nitric oxide synthase through activation of peroxisome proliferator-activated receptor-γ by flavonoids in mouse macrophages

FEBS Letters

Volumn 496, Issue 1, 2001, Pages 12-18

  Liang, Yu Chih ^a,b   Tsai, Shu Huei ^a   Tsai, De Cheng ^a   Lin Shiau, Shoei Yn ^a   Lin, Jen Kun ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cyclooxygenase; Flavonoid; Inflammation; Lipopolysaccharide; Nitric oxide synthase; Peroxisome proliferator activated receptor

Indexed keywords

APIGENIN; CHRYSIN; CYCLOOXYGENASE 2; FLAVANONE DERIVATIVE; FLAVONE DERIVATIVE; FLAVONOID; FLAVONOL DERIVATIVE; ISOFLAVONE DERIVATIVE; KAEMPFEROL; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEINASE; ROSIGLITAZONE; THEAFLAVIN 3,3' DIGALLATE; TRANSCRIPTION FACTOR;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INHIBITION; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; STRUCTURE ACTIVITY RELATION;

ANIMALS; APIGENIN; BINDING, COMPETITIVE; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLAVONOIDS; GENES, REPORTER; KAEMPFEROLS; MACROPHAGES; MICE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROMOTER REGIONS (GENETICS); PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN BINDING; QUERCETIN; RECEPTORS, CYTOPLASMIC AND NUCLEAR; THIAZOLES; THIAZOLIDINEDIONES; TRANSCRIPTION FACTORS;

EID: 0035805144     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(01)02393-6     Document Type: Article

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