-
1
-
-
0032475973
-
Sequence characteristics, subcellular localization and substrate specificity of Dyrk-related kinases, a novel family of dual specificity protein kinases
-
Becker, W., Weber, Y., Wetzel, K., Eirmbter, K., Tejedor, F., and Joost, H.-G. (1998) Sequence characteristics, subcellular localization and substrate specificity of Dyrk-related kinases, a novel family of dual specificity protein kinases. J Biol Chem. 273, 25,893-25,902.
-
(1998)
J Biol Chem.
, vol.273
-
-
Becker, W.1
Weber, Y.2
Wetzel, K.3
Eirmbter, K.4
Tejedor, F.5
Joost, H.-G.6
-
2
-
-
0343221565
-
Novel dual-specific tyr-thr/ser kinase cloned from colon carcinoma cells
-
Lee, K. and Friedman, E. (1998) Novel dual-specific tyr-thr/ser kinase cloned from colon carcinoma cells. Proc AACR. 39, 273.
-
(1998)
Proc AACR.
, vol.39
, pp. 273
-
-
Lee, K.1
Friedman, E.2
-
3
-
-
0034235542
-
Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells
-
Lee, K., Deng, X., and Friedman, E. (2000) Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells. Cancer Res. 60, 3631-3637.
-
(2000)
Cancer Res.
, vol.60
, pp. 3631-3637
-
-
Lee, K.1
Deng, X.2
Friedman, E.3
-
4
-
-
0033582339
-
Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases
-
Leder, S., Weber, Y., Altafaj, X., Estivill, X., Joost, H. G., and Becker, W. (1999) Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases. Biochem. Biophys. Res. Commun. 254, 474-479.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.254
, pp. 474-479
-
-
Leder, S.1
Weber, Y.2
Altafaj, X.3
Estivill, X.4
Joost, H.G.5
Becker, W.6
-
5
-
-
0030022273
-
Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII
-
Kentrup, H., Becker, W., Heukelbach, J., et al. (1996) Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII. J. Biol. Chem. 271, 3488-3495.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3488-3495
-
-
Kentrup, H.1
Becker, W.2
Heukelbach, J.3
-
6
-
-
0032603540
-
Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity
-
Becker, W. and Joost, H. G. (1999) Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity. Prog. Nucleic Acids Res. Mol. Biol. 62, 1-17.
-
(1999)
Prog. Nucleic Acids Res. Mol. Biol.
, vol.62
, pp. 1-17
-
-
Becker, W.1
Joost, H.G.2
-
7
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning, G., Whyte, D. B., Martinez, R., Hunter, T., and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science 298, 1912-1934.
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
8
-
-
0442276554
-
The glamour and gloom of glycogen synthase kinase-3
-
Jope, R. S. and Johnson, G. V. (2004) The glamour and gloom of glycogen synthase kinase-3. Trends Biochem. Sci. 29, 95-102.
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 95-102
-
-
Jope, R.S.1
Johnson, G.V.2
-
9
-
-
2342655502
-
Manipulation of alternative splicing by a newly developed inhibitor of Clks
-
Muraki, M., Ohkawara, B., Hosoya, T., et al. (2004) Manipulation of alternative splicing by a newly developed inhibitor of Clks. J. Biol. Chem. 279, 24,246-24,254.
-
(2004)
J. Biol. Chem.
, vol.279
-
-
Muraki, M.1
Ohkawara, B.2
Hosoya, T.3
-
10
-
-
0030863326
-
In vivo regulation of alternative pre-mRNA splicing by the Clk1 protein kinase
-
Duncan, P. I., Stojdl, D. F., Marius, R. M., and Bell, J. C. (1997) In vivo regulation of alternative pre-mRNA splicing by the Clk1 protein kinase. Mol. Cell. Biol. 17, 5996-6001.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 5996-6001
-
-
Duncan, P.I.1
Stojdl, D.F.2
Marius, R.M.3
Bell, J.C.4
-
11
-
-
0027939858
-
The dual-specificity CLK kinase induces neuronal differentiation of PC12 cells
-
Myers, M. P., Murphy, M. B., and Landreth, G. (1994) The dual-specificity CLK kinase induces neuronal differentiation of PC12 cells. Mol. Cell. Biol. 14, 6954-6961.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 6954-6961
-
-
Myers, M.P.1
Murphy, M.B.2
Landreth, G.3
-
12
-
-
3343024236
-
Evolutionary constraints associated with functional specificity of the CMGC protein kinases MAPK, CDK, GSK, SRPK, DYRK, and CK2alpha
-
Kannan, N. and Neuwald, A. F. (2004) Evolutionary constraints associated with functional specificity of the CMGC protein kinases MAPK, CDK, GSK, SRPK, DYRK, and CK2alpha. Protein Sci. 13, 2059-2077.
-
(2004)
Protein Sci.
, vol.13
, pp. 2059-2077
-
-
Kannan, N.1
Neuwald, A.F.2
-
13
-
-
0032515325
-
Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles
-
Kuroyanagi, N., Onogi, H., Wakabayashi, T., and Hagiwara, M. (1998) Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles. Biochem. Biophys. Res. Commun. 242, 357-364.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.242
, pp. 357-364
-
-
Kuroyanagi, N.1
Onogi, H.2
Wakabayashi, T.3
Hagiwara, M.4
-
14
-
-
9844236474
-
Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome
-
Wang, A., Forman-Kay, J., Luo, Y., et al. (1997) Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome. Hum. Mol. Genet. 6, 2117-2126.
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 2117-2126
-
-
Wang, A.1
Forman-Kay, J.2
Luo, Y.3
-
15
-
-
0039652688
-
Functional analysis of the fission yeast Prp4 protein kinase involved in pre-mRNA splicing and isolation of a putative mammalian homologue
-
Gross, T., Lutzelberger, M., Weigmann, H., Klingenhoff, A., Shenoy S., and Kaufer, N. F. (1997) Functional analysis of the fission yeast Prp4 protein kinase involved in pre-mRNA splicing and isolation of a putative mammalian homologue. Nucleic Acids Res. 25, 1028-1035.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 1028-1035
-
-
Gross, T.1
Lutzelberger, M.2
Weigmann, H.3
Klingenhoff, A.4
Shenoy, S.5
Kaufer, N.F.6
-
16
-
-
0032559642
-
SRPK2: A differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells
-
Wang, H. Y., Lin, W., Dyck, J. A., et al. (1998) SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells. J. Cell Biol. 140, 737-750.
-
(1998)
J. Cell Biol.
, vol.140
, pp. 737-750
-
-
Wang, H.Y.1
Lin, W.2
Dyck, J.A.3
-
17
-
-
0345898928
-
Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors
-
Kim, Y. H., Choi, C. Y., Lee, S. J., Conti, M. A., and Kim, Y. (1998) Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors. J. Biol. Chem. 273, 25,875-25,879.
-
(1998)
J. Biol. Chem.
, vol.273
-
-
Kim, Y.H.1
Choi, C.Y.2
Lee, S.J.3
Conti, M.A.4
Kim, Y.5
-
18
-
-
0033135902
-
Human minibrain homologue (MNBH/DYRK1): Characterization, alternative splicing, differential tissue expression and overexpression in Down syndrome
-
Guimera, J., Casas, C., Estivill, X., and Pritchard, M. (1999) Human minibrain homologue (MNBH/DYRK1): characterization, alternative splicing, differential tissue expression and overexpression in Down syndrome. Genomics 57, 407-418.
-
(1999)
Genomics
, vol.57
, pp. 407-418
-
-
Guimera, J.1
Casas, C.2
Estivill, X.3
Pritchard, M.4
-
19
-
-
0028839101
-
Minibrain: A new protein kinase family involved in postembryonic neurogenesis in Drosophila
-
Tejedor, F., Zhu, X. R., Kaltenbach, E., et al. (1995) Minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila. Neuron 14, 287-301.
-
(1995)
Neuron
, vol.14
, pp. 287-301
-
-
Tejedor, F.1
Zhu, X.R.2
Kaltenbach, E.3
-
20
-
-
1542614438
-
The MNB/DYRK1A protein kinase: Genetic and biochemical properties
-
Galceran, J., de Graaf, K., Tejedor, F. J., and Becker, W. (2003) The MNB/DYRK1A protein kinase: genetic and biochemical properties. J. Neural Transm. Suppl. 67, 139-148.
-
(2003)
J. Neural Transm. Suppl.
, vol.67
, pp. 139-148
-
-
Galceran, J.1
De Graaf, K.2
Tejedor, F.J.3
Becker, W.4
-
21
-
-
17744416567
-
The MNB/DYRK1A protein kinase: Neurobiological functions and Down syndrome implications
-
Hammerle, B., Elizalde, C., Galceran, J., Becker, W., and Tejedor, F. J. (2003) The MNB/DYRK1A protein kinase: neurobiological functions and Down syndrome implications. J. Neural. Transm. Suppl. 67, 129-137.
-
(2003)
J. Neural. Transm. Suppl.
, vol.67
, pp. 129-137
-
-
Hammerle, B.1
Elizalde, C.2
Galceran, J.3
Becker, W.4
Tejedor, F.J.5
-
22
-
-
0035445736
-
Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome
-
Altafaj, X., Dierssen, M., Baamonde, C., et al. (2001) Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome. Hum. Mol. Genet. 10, 1915-1923.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1915-1923
-
-
Altafaj, X.1
Dierssen, M.2
Baamonde, C.3
-
23
-
-
0036724569
-
Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice
-
Fotaki, V., Dierssen, M., Alcantara, S., et al. (2002) Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice. Mol. Cell Biol. 22, 6636-6647.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 6636-6647
-
-
Fotaki, V.1
Dierssen, M.2
Alcantara, S.3
-
24
-
-
3242816217
-
Haploinsufficiency of Dyrk1A in mice leads to specific alterations in the development and regulation of motor activity
-
Fotaki, V., Martinez De Lagran, M., Estivill, X., Arbones, M., and Dierssen, M. (2004) Haploinsufficiency of Dyrk1A in mice leads to specific alterations in the development and regulation of motor activity. Behav. Neurosci. 118, 815-821.
-
(2004)
Behav. Neurosci.
, vol.118
, pp. 815-821
-
-
Fotaki, V.1
Martinez De Lagran, M.2
Estivill, X.3
Arbones, M.4
Dierssen, M.5
-
25
-
-
0035955696
-
Protein kinase Dyrk1 activates cAMP response element-binding protein during neuronal differentiation in hippocampal progenitor cells
-
Yang, E., Ahn, Y. S., and Chung, K. (2001) Protein kinase Dyrk1 activates cAMP response element-binding protein during neuronal differentiation in hippocampal progenitor cells. J. Biol. Chem. 276, 39,819-39,824.
-
(2001)
J. Biol. Chem.
, vol.276
-
-
Yang, E.1
Ahn, Y.S.2
Chung, K.3
-
26
-
-
0037428280
-
Unusual function of the activation loop in the protein kinase DYRK1A
-
Wiechmann, S., Czajkowska, H., de Graaf, K., Grotzinger, J., Joost, H. G., and Becker, W. (2003) Unusual function of the activation loop in the protein kinase DYRK1A. Biochem. Biophys. Res. Commun. 302, 403-408.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.302
, pp. 403-408
-
-
Wiechmann, S.1
Czajkowska, H.2
De Graaf, K.3
Grotzinger, J.4
Joost, H.G.5
Becker, W.6
-
27
-
-
0035174668
-
A new expression cloning strategy for isolation of substrate-specific kinases by using phosphorylation site-specific antibody
-
Matsuo, R., Ochiai, W., Nakashima, K., and Taga, T. (2001) A new expression cloning strategy for isolation of substrate-specific kinases by using phosphorylation site-specific antibody. J. Immunol. Methods 247, 141-151.
-
(2001)
J. Immunol. Methods
, vol.247
, pp. 141-151
-
-
Matsuo, R.1
Ochiai, W.2
Nakashima, K.3
Taga, T.4
-
28
-
-
0037144506
-
Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1
-
Mao, J., Maye, P., Kogerman, P., et al. (2002) Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1. J. Biol. Chem. 277, 35,156-35,161.
-
(2002)
J. Biol. Chem.
, vol.277
-
-
Mao, J.1
Maye, P.2
Kogerman, P.3
-
29
-
-
0037449888
-
DYRK1 is a co-activator of FKHR (FOXO1a)-dependent glucose-6-phosphatase gene expression
-
von Groote-Bidlingmaier, F., Schmoll, D., Orth, H. M., Joost, H. G., Becker, W., and Barthel, A. (2003) DYRK1 is a co-activator of FKHR (FOXO1a)-dependent glucose-6-phosphatase gene expression. Biochem. Biophys. Res. Commun. 300, 764-769.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.300
, pp. 764-769
-
-
Von Groote-Bidlingmaier, F.1
Schmoll, D.2
Orth, H.M.3
Joost, H.G.4
Becker, W.5
Barthel, A.6
-
30
-
-
0035340356
-
The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site
-
Woods, Y. L., Rena, G., Morrice, N., et al. (2001) The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site. Biochem. J. 355, 597-607.
-
(2001)
Biochem. J.
, vol.355
, pp. 597-607
-
-
Woods, Y.L.1
Rena, G.2
Morrice, N.3
-
31
-
-
0035340295
-
The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: Potential role for DYRK as a glycogen synthase kinase 3-priming kinase
-
Woods, Y. L., Cohen, P., Becker, W., et al. (2001) The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase. Biochem. J. 355, 609-615.
-
(2001)
Biochem. J.
, vol.355
, pp. 609-615
-
-
Woods, Y.L.1
Cohen, P.2
Becker, W.3
-
32
-
-
0037124086
-
Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate
-
Chen-Hwang, M. C., Chen, H. R., Elzinga, M., and Hwang, Y. W. (2002) Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate. J. Biol. Chem. 277, 17,597-17,604.
-
(2002)
J. Biol. Chem.
, vol.277
-
-
Chen-Hwang, M.C.1
Chen, H.R.2
Elzinga, M.3
Hwang, Y.W.4
-
33
-
-
1042266636
-
Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: Phosphorylation by DYRK1A and colocalization with splicing factors
-
de Graaf, K., Hekerman, P., Spelten, O., et al. (2004) Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors. J. Biol. Chem. 279, 4612-4624.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4612-4624
-
-
De Graaf, K.1
Hekerman, P.2
Spelten, O.3
-
34
-
-
0041672360
-
Amplification and overexpression of the dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) gene in esophageal and lung adenocarcinomas
-
Miller, C. T., Aggarwal, S., Lin, T. K., et al. (2003) Amplification and overexpression of the dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) gene in esophageal and lung adenocarcinomas. Cancer Res. 63, 4136-4143.
-
(2003)
Cancer Res.
, vol.63
, pp. 4136-4143
-
-
Miller, C.T.1
Aggarwal, S.2
Lin, T.K.3
-
35
-
-
0035865612
-
mDYRK3 kinase is expressed selectively in late erythroid progenitor cells and attenuates colony-forming unit-erythroid development
-
Geiger, J. N., Knudsen, G. T., Panek, L., et al. (2001) mDYRK3 kinase is expressed selectively in late erythroid progenitor cells and attenuates colony-forming unit-erythroid development. Blood 97, 901-910.
-
(2001)
Blood
, vol.97
, pp. 901-910
-
-
Geiger, J.N.1
Knudsen, G.T.2
Panek, L.3
-
36
-
-
10644270731
-
DYRK gene structure and erythroid-restricted features of DYRK3 gene expression
-
Zhang, D., Li, K., Erickson-Miller, C. L., Weiss, M., and Wojchowski, D. M. (2005) DYRK gene structure and erythroid-restricted features of DYRK3 gene expression. Genomics 85, 117-130.
-
(2005)
Genomics
, vol.85
, pp. 117-130
-
-
Zhang, D.1
Li, K.2
Erickson-Miller, C.L.3
Weiss, M.4
Wojchowski, D.M.5
-
37
-
-
0034192147
-
REDK, a novel human regulatory erythroid kinase
-
Lord, K. A., Creasy, C. L., King, A. G., et al. (2000) REDK, a novel human regulatory erythroid kinase. Blood 95, 2838-2846.
-
(2000)
Blood
, vol.95
, pp. 2838-2846
-
-
Lord, K.A.1
Creasy, C.L.2
King, A.G.3
-
38
-
-
0037033107
-
DYRK3 activation, engagement of protein kinase A/cAMP response element-binding protein, and modulation of progenitor cell survival
-
Li, K., Zhao, S., Karur, V., and Wojchowski, D. M. (2002) DYRK3 activation, engagement of protein kinase A/cAMP response element-binding protein, and modulation of progenitor cell survival. J. Biol. Chem. 277, 47,052-47,060.
-
(2002)
J. Biol. Chem.
, vol.277
-
-
Li, K.1
Zhao, S.2
Karur, V.3
Wojchowski, D.M.4
-
39
-
-
21844468764
-
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts
-
Mercer, S. E., Ewton, D. Z., Deng, X., Lim, S., Mazur, T. R., and Friedman, E. (2005) Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts. J. Biol. Chem. 280, 25,788-25,801.
-
(2005)
J. Biol. Chem.
, vol.280
-
-
Mercer, S.E.1
Ewton, D.Z.2
Deng, X.3
Lim, S.4
Mazur, T.R.5
Friedman, E.6
-
40
-
-
20444419344
-
Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
-
Mackeigan, J. P., Murphy, L. O., and Blenis, J. (2005) Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. Nat. Cell Biol. 7, 591-600.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 591-600
-
-
Mackeigan, J.P.1
Murphy, L.O.2
Blenis, J.3
-
41
-
-
0035152895
-
Identification of genes up-regulated by retinoic-acid-induced differentiation of the human neuronal precursor cell line NTERA-2 clD1
-
Leypoldt, F., Lewerenz, J., and Methner, A. (2001) Identification of genes up-regulated by retinoic-acid-induced differentiation of the human neuronal precursor cell line NTERA-2 clD1. J. Neurochem. 76, 806-814.
-
(2001)
J. Neurochem.
, vol.76
, pp. 806-814
-
-
Leypoldt, F.1
Lewerenz, J.2
Methner, A.3
-
42
-
-
0042330069
-
dDYRK2: A novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila
-
Lochhead, P. A., Sibbet, G., Kinstrie, R., Cleghon, T., Rylatt, M., Morrison, D. K., and Cleghon, V. (2003) dDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila. Biochem. J. 374, 381-391.
-
(2003)
Biochem. J.
, vol.374
, pp. 381-391
-
-
Lochhead, P.A.1
Sibbet, G.2
Kinstrie, R.3
Cleghon, T.4
Rylatt, M.5
Morrison, D.K.6
Cleghon, V.7
-
43
-
-
0037297691
-
Characterization of Caenorhabditis elegans homologs of the Down syndrome candidate gene DYRK1A
-
Raich, W. B., Moorman, C., Lacefield, C. O., et al. (2003) Characterization of Caenorhabditis elegans homologs of the Down syndrome candidate gene DYRK1A. Genetics 163, 571-580.
-
(2003)
Genetics
, vol.163
, pp. 571-580
-
-
Raich, W.B.1
Moorman, C.2
Lacefield, C.O.3
-
44
-
-
0347623127
-
The minibrain kinase homolog, mbk-2, is required for spindle positioning and asymmetric cell division in early C. elegans embryos
-
Pang, K. M., Ishidate, T., Nakamura, K., et al. (2004) The minibrain kinase homolog, mbk-2, is required for spindle positioning and asymmetric cell division in early C. elegans embryos. Dev. Biol. 265, 127-139.
-
(2004)
Dev. Biol.
, vol.265
, pp. 127-139
-
-
Pang, K.M.1
Ishidate, T.2
Nakamura, K.3
-
45
-
-
0034213189
-
Saccharomyces cerevisiae Yak1p protein kinase autophosphorylates on tyrosine residues and phosphorylates myelin basic protein on a C-terminal serine residue
-
Kassis, S., Melhuish, T., Annan, R. S., et al. (2000) Saccharomyces cerevisiae Yak1p protein kinase autophosphorylates on tyrosine residues and phosphorylates myelin basic protein on a C-terminal serine residue. Biochem. J. 348, 263-272.
-
(2000)
Biochem. J.
, vol.348
, pp. 263-272
-
-
Kassis, S.1
Melhuish, T.2
Annan, R.S.3
-
46
-
-
0035873250
-
Yak1p, a DYRK family kinase, translocates to the nucleus and phosphorylates yeast Pop2p in response to a glucose signal
-
Moriya, H., Shimizu-Yoshida, Y., Omori, A., Iwashita, S., Katoh, M., and Sakai, A. (2001) Yak1p, a DYRK family kinase, translocates to the nucleus and phosphorylates yeast Pop2p in response to a glucose signal. Genes Dev. 150, 1217-1228.
-
(2001)
Genes Dev.
, vol.150
, pp. 1217-1228
-
-
Moriya, H.1
Shimizu-Yoshida, Y.2
Omori, A.3
Iwashita, S.4
Katoh, M.5
Sakai, A.6
-
47
-
-
0040839027
-
Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis
-
Bahler, J. and Pringle, J. R. (1998) Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis. Genes Dev. 12, 1356-1370.
-
(1998)
Genes Dev.
, vol.12
, pp. 1356-1370
-
-
Bahler, J.1
Pringle, J.R.2
-
48
-
-
0036328285
-
Role for YakA, cAMP, and protein kinase A in regulation of stress responses of Dictyostelium discoideum
-
Taminato, A., Bagattini, R., Gorjao, R., Chen, G., Kuspa, A., and Souza, G. M. (2002) Role for YakA, cAMP, and protein kinase A in regulation of stress responses of Dictyostelium discoideum. Mol. Biol. Cell. 13, 2266-2275.
-
(2002)
Mol. Biol. Cell.
, vol.13
, pp. 2266-2275
-
-
Taminato, A.1
Bagattini, R.2
Gorjao, R.3
Chen, G.4
Kuspa, A.5
Souza, G.M.6
-
49
-
-
0024723687
-
Loss of Ras activity in Saccharomyces cerevisiae is suppressed by disruptions of a new kinase gene, YAKI, whose product may act downstream of the cAMP-dependent protein kinase
-
Garrett, S. and Broach, J. (1989) Loss of Ras activity in Saccharomyces cerevisiae is suppressed by disruptions of a new kinase gene, YAKI, whose product may act downstream of the cAMP-dependent protein kinase. Genes Dev. 3, 1336-1348.
-
(1989)
Genes Dev.
, vol.3
, pp. 1336-1348
-
-
Garrett, S.1
Broach, J.2
-
50
-
-
0025851170
-
The Saccharomyces cerevisiae YAK1 gene encodes a protein kinase that is induced by arrest early in the cell cycle
-
Garrett, S., Menold, M. M., and Broach, J. R. (1991) The Saccharomyces cerevisiae YAK1 gene encodes a protein kinase that is induced by arrest early in the cell cycle. Mol. Cell. Biol. 11, 4045-4052.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 4045-4052
-
-
Garrett, S.1
Menold, M.M.2
Broach, J.R.3
-
51
-
-
0035283205
-
Fission yeast Pom1p kinase activity is cell cycle regulated and essential for cellular symmetry during growth and division
-
Bahler, J. and Nurse, P. (2001) Fission yeast Pom1p kinase activity is cell cycle regulated and essential for cellular symmetry during growth and division. EMBO J. 20, 1064-1073.
-
(2001)
EMBO J.
, vol.20
, pp. 1064-1073
-
-
Bahler, J.1
Nurse, P.2
-
52
-
-
0032767435
-
Starvation promotes Dictyostelium development by relieving PufA inhibition of PKA translation through the YakA kinase pathway
-
Souza, G. M., da Silva, A. M., and Kuspa, A. (1999) Starvation promotes Dictyostelium development by relieving PufA inhibition of PKA translation through the YakA kinase pathway. Development 126, 3263-3274.
-
(1999)
Development
, vol.126
, pp. 3263-3274
-
-
Souza, G.M.1
Da Silva, A.M.2
Kuspa, A.3
-
53
-
-
0041885252
-
DYRK1A accumulates in splicing speckles through a novel targeting signal and induces speckle disassembly
-
Alvarez, M., Estivill, X., and de la Luna, S. (2003) DYRK1A accumulates in splicing speckles through a novel targeting signal and induces speckle disassembly. J. Cell Sci. 116, 3099-3107.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 3099-3107
-
-
Alvarez, M.1
Estivill, X.2
De La Luna, S.3
-
54
-
-
0038391317
-
Expression patterns and subcellular localization of the Down syndrome candidate protein MNB/DYRK1 A suggest a role in late neuronal differentiation
-
Hammerle, B., Carnicero, A., Elizalde, C., Ceron, J., Martinez, S., and Tejedor, F. J. (2003) Expression patterns and subcellular localization of the Down syndrome candidate protein MNB/DYRK1 A suggest a role in late neuronal differentiation. Eur. J. Neurosci. 17, 2277-2286.
-
(2003)
Eur. J. Neurosci.
, vol.17
, pp. 2277-2286
-
-
Hammerle, B.1
Carnicero, A.2
Elizalde, C.3
Ceron, J.4
Martinez, S.5
Tejedor, F.J.6
-
55
-
-
0037469923
-
Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system
-
Marti, E., Altafaj, X., Dierssen, M., et al. (2003) Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system. Brain Res. 964, 250-263.
-
(2003)
Brain Res.
, vol.964
, pp. 250-263
-
-
Marti, E.1
Altafaj, X.2
Dierssen, M.3
-
56
-
-
2342562539
-
Cell type-and brain structure-specific patterns of distribution of minibrain kinase in human brain
-
Wegiel, J., Kuchna, I., Nowicki, K., et al. (2004) Cell type-and brain structure-specific patterns of distribution of minibrain kinase in human brain. Brain Res. 1010, 69-80.
-
(2004)
Brain Res.
, vol.1010
, pp. 69-80
-
-
Wegiel, J.1
Kuchna, I.2
Nowicki, K.3
-
57
-
-
33646247855
-
The kinase Mirk/ Dyrk1B mediates cell survival in pancreatic ductal adenocarcinoma
-
in press
-
Deng, X., Ewton, D. Z., Li, S. (2006) The kinase Mirk/ Dyrk1B mediates cell survival in pancreatic ductal adenocarcinoma. Cancer Res. in press.
-
(2006)
Cancer Res.
-
-
Deng, X.1
Ewton, D.Z.2
Li, S.3
-
58
-
-
33646265602
-
Mirk/Dyrk 1B mediates cell wurvival in rabdomyosarcomas
-
in press
-
Mercer, S. E., Ewton, D. Z., Shah, S., Naqvi, A. and Friedman, E. (2006) Mirk/Dyrk 1B mediates cell wurvival in rabdomyosarcomas. Cancer Res., in press.
-
(2006)
Cancer Res.
-
-
Mercer, S.E.1
Ewton, D.Z.2
Shah, S.3
Naqvi, A.4
Friedman, E.5
-
59
-
-
0033590164
-
Distantly related cousins of MAP kinase: Biochemical properties and possible physiological functions
-
Miyata, Y. and Nishida, E. (1999) Distantly related cousins of MAP kinase: biochemical properties and possible physiological functions. Biochem. Biophys. Res. Commun. 266, 291-295.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.266
, pp. 291-295
-
-
Miyata, Y.1
Nishida, E.2
-
60
-
-
0035504266
-
Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A
-
Himpel, S., Panzer, P., Eirmbter, K., et al. (2001) Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A. Biochem. J. 359, 497-505.
-
(2001)
Biochem. J.
, vol.359
, pp. 497-505
-
-
Himpel, S.1
Panzer, P.2
Eirmbter, K.3
-
61
-
-
20444387985
-
Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs
-
Lochhead, P. A., Sibbet, G., Morrice, N., and Cleghon, V. (2005) Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs. Cell 121, 925-936.
-
(2005)
Cell
, vol.121
, pp. 925-936
-
-
Lochhead, P.A.1
Sibbet, G.2
Morrice, N.3
Cleghon, V.4
-
62
-
-
0037005887
-
Differing substrate specificities of members of the DYRK family of arginine-directed protein kinases
-
Campbell, L. E. and Proud, C. G. (2002) Differing substrate specificities of members of the DYRK family of arginine-directed protein kinases. FEBS Lett. 510, 31-36.
-
(2002)
FEBS Lett.
, vol.510
, pp. 31-36
-
-
Campbell, L.E.1
Proud, C.G.2
-
63
-
-
0034723403
-
Specificity determinants of substrate recognition by the protein kinase DYRK1A
-
Himpel, S., Tegge, W., Frank, R., Leder, S., Joost, H. G., and Becker, W. (2000) Specificity determinants of substrate recognition by the protein kinase DYRK1A. J. Biol. Chem. 275, 2431-2438.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2431-2438
-
-
Himpel, S.1
Tegge, W.2
Frank, R.3
Leder, S.4
Joost, H.G.5
Becker, W.6
-
64
-
-
2542489078
-
The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G(0) by Mirk/Dyrk1B kinase
-
Deng, X., Mercer, S. E., Shah, S., Ewton, D. Z., and Friedman, E. (2004) The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G(0) by Mirk/Dyrk1B kinase. J. Biol. Chem. 279, 22,498-22,504.
-
(2004)
J. Biol. Chem.
, vol.279
-
-
Deng, X.1
Mercer, S.E.2
Shah, S.3
Ewton, D.Z.4
Friedman, E.5
-
65
-
-
14244258401
-
Mirk/Dyrk1B decreases the nuclear accumulation of class II histone deacetylases during skeletal muscle differentiation
-
Deng, X., Ewton, D. Z., Mercer, S. E., and Friedman, E. (2005) Mirk/Dyrk1B decreases the nuclear accumulation of class II histone deacetylases during skeletal muscle differentiation. J. Biol. Chem. 280, 4894-4905.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 4894-4905
-
-
Deng, X.1
Ewton, D.Z.2
Mercer, S.E.3
Friedman, E.4
-
66
-
-
0037067736
-
Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha
-
Lim, S., Jin, K., and Friedman, E. (2002) Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha. J. Biol. Chem. 277, 25,040-25,046.
-
(2002)
J. Biol. Chem.
, vol.277
-
-
Lim, S.1
Jin, K.2
Friedman, E.3
-
67
-
-
3042684281
-
Mirk/Dyrk1B kinase destabilizes cyclin D1 by phosphorylation at threonine 288
-
Zou, Y., Ewton, D. Z., Deng, X., Mercer, S. E., and Friedman, E. (2004) Mirk/Dyrk1B kinase destabilizes cyclin D1 by phosphorylation at threonine 288. J. Biol. Chem. 279, 27,790-27,798.
-
(2004)
J. Biol. Chem.
, vol.279
-
-
Zou, Y.1
Ewton, D.Z.2
Deng, X.3
Mercer, S.E.4
Friedman, E.5
-
68
-
-
1642535438
-
Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases
-
Skurat, A. V. and Dietrich, A. D. (2004) Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases. J. Biol. Chem. 279, 2490-2498.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 2490-2498
-
-
Skurat, A.V.1
Dietrich, A.D.2
-
69
-
-
0037591588
-
Alternative splicing variants of dual specificity tyrosine phosphorylated and regulated kinase 1B exhibit distinct patterns of expression and functional properties
-
Leder, S., Czajkowska, H., Maenz, B., et al. (2003) Alternative splicing variants of dual specificity tyrosine phosphorylated and regulated kinase 1B exhibit distinct patterns of expression and functional properties. Biochem. J. 372, 881-888.
-
(2003)
Biochem. J.
, vol.372
, pp. 881-888
-
-
Leder, S.1
Czajkowska, H.2
Maenz, B.3
-
70
-
-
0142071703
-
Mirk/Dyrk1B is a rho-induced kinase active in skeletal muscle differentiation
-
Deng, X., Ewton, D., Pawlikowski, B., Maimone, M., and Friedman, E. (2003) Mirk/Dyrk1B is a rho-induced kinase active in skeletal muscle differentiation. J. Biol. Chem. 278, 41,347-41,354.
-
(2003)
J. Biol. Chem.
, vol.278
-
-
Deng, X.1
Ewton, D.2
Pawlikowski, B.3
Maimone, M.4
Friedman, E.5
-
71
-
-
0022971952
-
Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis
-
Rogers, S., Wells, R., and Rechsteiner, M. (1986) Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis. Science 234, 364-368.
-
(1986)
Science
, vol.234
, pp. 364-368
-
-
Rogers, S.1
Wells, R.2
Rechsteiner, M.3
-
72
-
-
0030200110
-
PEST sequences and regulation by proteolysis
-
Rechsteiner, M. and Rogers, S. W. (1996) PEST sequences and regulation by proteolysis. Trends Biochem. Sci. 21, 267-271.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 267-271
-
-
Rechsteiner, M.1
Rogers, S.W.2
-
73
-
-
0037147222
-
The transcriptional activator Mirk/Dyrk1B is sequestered by p38alpha/beta MAP kinase
-
Lim, S., Zou, Y., and Friedman, E. (2002) The transcriptional activator Mirk/Dyrk1B is sequestered by p38alpha/beta MAP kinase. J. Biol. Chem. 277, 49,438-49,445.
-
(2002)
J. Biol. Chem.
, vol.277
-
-
Lim, S.1
Zou, Y.2
Friedman, E.3
-
74
-
-
0037423671
-
Myocyte death, growth, and regeneration in cardiac hypertrophy and failure
-
Nadal-Ginard, B., Kajstura, J., Leri, A., and Anversa, P. (2003) Myocyte death, growth, and regeneration in cardiac hypertrophy and failure. Circ. Res. 92, 139-150.
-
(2003)
Circ. Res.
, vol.92
, pp. 139-150
-
-
Nadal-Ginard, B.1
Kajstura, J.2
Leri, A.3
Anversa, P.4
-
75
-
-
0038707590
-
Molecular pathways in myocardial development: A stem cell perspective
-
Solloway M. J. and Harvey, R. P. (2003) Molecular pathways in myocardial development: a stem cell perspective. Cardiovasc. Res. 58, 264-277.
-
(2003)
Cardiovasc. Res.
, vol.58
, pp. 264-277
-
-
Solloway, M.J.1
Harvey, R.P.2
-
76
-
-
0042337388
-
Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy
-
Urbanek, K., Quaini, F., Tasca, G., et al. (2003) Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy. Proc. Natl. Acad. Sci. USA 100, 10,440-10,445.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
-
-
Urbanek, K.1
Quaini, F.2
Tasca, G.3
-
77
-
-
10744228523
-
Adult cardiac stem cells are multipotent and support myocardial regeneration
-
Beltrami, A. P., Barlucchi, L., Torella, D., et al. (2003) Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 114, 763-776.
-
(2003)
Cell
, vol.114
, pp. 763-776
-
-
Beltrami, A.P.1
Barlucchi, L.2
Torella, D.3
-
78
-
-
0037211485
-
Rapid turnover of cell-cycle regulators found in Mirk/Dyrk1B transfectants
-
Ewton, D. Z., Lee, K., Deng, X., Lim, S., and Friedman, E. (2003) Rapid turnover of cell-cycle regulators found in Mirk/Dyrk1B transfectants. Int. J. Cancer 103, 21-28.
-
(2003)
Int. J. Cancer
, vol.103
, pp. 21-28
-
-
Ewton, D.Z.1
Lee, K.2
Deng, X.3
Lim, S.4
Friedman, E.5
-
79
-
-
0034635987
-
Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases
-
Lu, J., McKinsey T. A., Nicol, R. L., and Olson, E. N. (2000) Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases. Proc. Natl. Acad. Sci. USA 97, 4070-4075.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4070-4075
-
-
Lu, J.1
McKinsey, T.A.2
Nicol, R.L.3
Olson, E.N.4
-
80
-
-
0035480033
-
Control of muscle development by dueling HATs and HDACs
-
McKinsey, T. A., Zhang, C. L., and Olson, E. N. (2001) Control of muscle development by dueling HATs and HDACs. Curr. Opin. Genet. Dev. 11, 497-504.
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 497-504
-
-
McKinsey, T.A.1
Zhang, C.L.2
Olson, E.N.3
-
81
-
-
0033635242
-
Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases
-
Lu, J., McKinsey, T. A., Zhang, C. L., and Olson, E. N. (2000) Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases. Mol Cell 6, 233-244.
-
(2000)
Mol Cell
, vol.6
, pp. 233-244
-
-
Lu, J.1
McKinsey, T.A.2
Zhang, C.L.3
Olson, E.N.4
-
82
-
-
0033104495
-
Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation
-
Asada, M., Yamada, T., Ichijo, H., et al. (1999) Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation. EMBO J. 18, 1223-1234.
-
(1999)
EMBO J.
, vol.18
, pp. 1223-1234
-
-
Asada, M.1
Yamada, T.2
Ichijo, H.3
-
83
-
-
0034745353
-
Cytoplasmic localization of p21cip1/waf1 by Akt-induced phosphorylation in HER-2/Neu-overexpressing cells
-
Zhou, B., Liao, Y., Xia, W., Lee, M.-H., and Hung, M.-C. (2001) Cytoplasmic localization of p21cip1/waf1 by Akt-induced phosphorylation in HER-2/Neu-overexpressing cells. Nat. Cell Biol. 3, 245-252.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 245-252
-
-
Zhou, B.1
Liao, Y.2
Xia, W.3
Lee, M.-H.4
Hung, M.-C.5
-
84
-
-
2542640227
-
Phosphorylation/cytoplasmic localization of p21Cip1/WAF1 is associated with HER2/neu overexpression and provides a novel combination predictor for poor prognosis in breast cancer patients
-
Xia, W., Chen, J. S., Zhou, X. et al. (2004) Phosphorylation/cytoplasmic localization of p21Cip1/WAF1 is associated with HER2/neu overexpression and provides a novel combination predictor for poor prognosis in breast cancer patients. Clin. Cancer Res. 10, 3815-3824.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 3815-3824
-
-
Xia, W.1
Chen, J.S.2
Zhou, X.3
-
85
-
-
0042197268
-
Are p27 and p21 cytoplasmic oncoproteins?
-
Blagosklonny, M. V. (2002) Are p27 and p21 cytoplasmic oncoproteins? Cell Cycle 1, 391-393.
-
(2002)
Cell Cycle
, vol.1
, pp. 391-393
-
-
Blagosklonny, M.V.1
-
86
-
-
0029996726
-
Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation
-
Wang, J. and Walsh, K. (1996) Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation. Science 273, 359-361.
-
(1996)
Science
, vol.273
, pp. 359-361
-
-
Wang, J.1
Walsh, K.2
-
87
-
-
0037157872
-
Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity
-
Tanaka, H., Yamashita, T., Asada, M., Mizutani, S., Yoshikawa, H., and Tohyama, M. (2002) Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity. J. Cell Biol. 158, 321-329.
-
(2002)
J. Cell Biol.
, vol.158
, pp. 321-329
-
-
Tanaka, H.1
Yamashita, T.2
Asada, M.3
Mizutani, S.4
Yoshikawa, H.5
Tohyama, M.6
-
88
-
-
3042552705
-
Cytoplasmic p21(Cip1/WAF1) enhances axonal regeneration and functional recovery after spinal cord injury in rats
-
Tanaka, H., Yamashita, T., Yachi, K., Fujiwara, T., Yoshikawa, H., and Tohyama, M. (2004) Cytoplasmic p21(Cip1/WAF1) enhances axonal regeneration and functional recovery after spinal cord injury in rats. Neuroscience 127, 155-164.
-
(2004)
Neuroscience
, vol.127
, pp. 155-164
-
-
Tanaka, H.1
Yamashita, T.2
Yachi, K.3
Fujiwara, T.4
Yoshikawa, H.5
Tohyama, M.6
-
89
-
-
0033588883
-
Rhabdomyosarcoma - Working out the pathways
-
Merlino, G. and Helman, L. J. (1999) Rhabdomyosarcoma - working out the pathways. Oncogene. 18, 5340-5348.
-
(1999)
Oncogene
, vol.18
, pp. 5340-5348
-
-
Merlino, G.1
Helman, L.J.2
-
90
-
-
16844382968
-
Signaling intricacies take center stage in cancer cells
-
Kumar, R. and Hung, M. C. (2005) Signaling intricacies take center stage in cancer cells. Cancer Res. 65, 2511-2515.
-
(2005)
Cancer Res.
, vol.65
, pp. 2511-2515
-
-
Kumar, R.1
Hung, M.C.2
-
91
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
Vivanco, I. and Sawyers, C. L. (2002) The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat. Rev. Cancer 2, 489-501.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
92
-
-
2442763214
-
Overexpression of pterin-4a-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 in human colon cancer
-
Eskinazi, R., Thony B., Svoboda, M., et al. (1999) Overexpression of pterin-4a-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 in human colon cancer. Am. J. Pathol. 155, 1105-1113.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 1105-1113
-
-
Eskinazi, R.1
Thony, B.2
Svoboda, M.3
-
93
-
-
1542572178
-
Mirk/Dyrk1B is an inhibitor of epithelial cell migration which negatively regulated by the Met-adaptor ranBPM
-
Zou, Y., Lim, S., Lee, K., Deng, X., and Friedman, E. (2003) Mirk/Dyrk1B is an inhibitor of epithelial cell migration which negatively regulated by the Met-adaptor ranBPM. J. Biol. Chem. 278, 49,573-49,581.
-
(2003)
J. Biol. Chem.
, vol.278
-
-
Zou, Y.1
Lim, S.2
Lee, K.3
Deng, X.4
Friedman, E.5
-
94
-
-
0037183982
-
Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM
-
Wang, D., Li, Z., Messing, E. M., and Wu, G. (2002) Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM. J. Biol. Chem. 277, 36,216-36,222.
-
(2002)
J. Biol. Chem.
, vol.277
-
-
Wang, D.1
Li, Z.2
Messing, E.M.3
Wu, G.4
-
95
-
-
0011701480
-
Retrogenic expression of the MET proto-oncogene correlates with the invasive phenotype of human rhabdomyosarcomas
-
Ferracini, R., Olivero, M., Di Renzo, M. F., et al. (1996) Retrogenic expression of the MET proto-oncogene correlates with the invasive phenotype of human rhabdomyosarcomas. Oncogene 12, 1697-1705.
-
(1996)
Oncogene
, vol.12
, pp. 1697-1705
-
-
Ferracini, R.1
Olivero, M.2
Di Renzo, M.F.3
-
96
-
-
0036851869
-
Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis
-
Sharp, R., Recio, J. A., Jhappan, C., et al. (2002) Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis. Nat. Med. 8, 1276-1280.
-
(2002)
Nat. Med.
, vol.8
, pp. 1276-1280
-
-
Sharp, R.1
Recio, J.A.2
Jhappan, C.3
-
97
-
-
0031037754
-
Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor
-
Takayama, H., LaRochelle, W. J., Sharp, R., et al. (1997) Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor. Proc. Natl. Acad. Sci. USA 94, 701-706.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 701-706
-
-
Takayama, H.1
Larochelle, W.J.2
Sharp, R.3
-
98
-
-
0037138389
-
How do 14-3-3 proteins work? - Gatekeeper phosphorylation and the molecular anvil hypothesis
-
Yaffe, M. B. (2002) How do 14-3-3 proteins work? - Gatekeeper phosphorylation and the molecular anvil hypothesis. FEBS Lett. 513, 53-57.
-
(2002)
FEBS Lett.
, vol.513
, pp. 53-57
-
-
Yaffe, M.B.1
-
99
-
-
4544320211
-
Regulation of Dyrk1A kinase activity by 14-3-3
-
Kim, D., Won, J., Shin, D. W., et al. (2004) Regulation of Dyrk1A kinase activity by 14-3-3. Biochem. Biophys. Res. Commun. 323, 499-504.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.323
, pp. 499-504
-
-
Kim, D.1
Won, J.2
Shin, D.W.3
-
100
-
-
0142052935
-
p21 is essential for normal myogenic progenitor cell function in regenerating skeletal muscle
-
Hawke, T. J., Meeson, A. P., Jiang, N., et al. (2003) p21 is essential for normal myogenic progenitor cell function in regenerating skeletal muscle. Am. J. Physiol. 285, C1019-C1027.
-
(2003)
Am. J. Physiol.
, vol.285
-
-
Hawke, T.J.1
Meeson, A.P.2
Jiang, N.3
-
101
-
-
4143066760
-
Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
-
Sordella, R., Bell, D. W., Haber, D. A., and Settleman, J. (2004) Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science 305, 1163-1167.
-
(2004)
Science
, vol.305
, pp. 1163-1167
-
-
Sordella, R.1
Bell, D.W.2
Haber, D.A.3
Settleman, J.4
-
102
-
-
4344591508
-
Enhanced redundancy in Akt and mitogen-activated protein kinase-induced survival of malignant versus normal prostate epithelial cells
-
Uzgare, A. R. and Isaacs, J. T. (2004) Enhanced redundancy in Akt and mitogen-activated protein kinase-induced survival of malignant versus normal prostate epithelial cells. Cancer Res. 64, 6190-6199.
-
(2004)
Cancer Res.
, vol.64
, pp. 6190-6199
-
-
Uzgare, A.R.1
Isaacs, J.T.2
|