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Volumn 6, Issue 12, 1997, Pages 2117-2126

Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; NUCLEAR RNA; PROTEIN SUBUNIT; SMALL NUCLEAR RIBONUCLEOPROTEIN; TRYPTOPHAN;

EID: 9844236474     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/6.12.2117     Document Type: Article
Times cited : (36)

References (54)
  • 1
    • 0026423013 scopus 로고
    • Messenger RNA splicing in yeast: Clues to why the spliceosome is a ribonucleoprotein
    • Guthrie, C. (1991) Messenger RNA splicing in yeast: clues to why the spliceosome is a ribonucleoprotein. Science, 253, 157-163.
    • (1991) Science , vol.253 , pp. 157-163
    • Guthrie, C.1
  • 2
    • 0025787954 scopus 로고
    • Biochemical mechanisms of constitutive and regulated pre-mRNA splicing
    • Green, M.R. (1991) Biochemical mechanisms of constitutive and regulated pre-mRNA splicing. Annu. Rev. Cell Biol., 7, 559-599.
    • (1991) Annu. Rev. Cell Biol. , vol.7 , pp. 559-599
    • Green, M.R.1
  • 3
    • 0023127048 scopus 로고
    • The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing
    • Maniatis, T. and Reed, R. (1987) The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing. Nature, 325, 673-678.
    • (1987) Nature , vol.325 , pp. 673-678
    • Maniatis, T.1    Reed, R.2
  • 4
    • 0029891101 scopus 로고    scopus 로고
    • The structure and function of proteins involved in mammalian pre-mRNA splicing
    • Kramer, A. (1996) The structure and function of proteins involved in mammalian pre-mRNA splicing. Annu. Rev. Biochcm., 65, 367-409.
    • (1996) Annu. Rev. Biochcm. , vol.65 , pp. 367-409
    • Kramer, A.1
  • 5
    • 0001877802 scopus 로고
    • Splicing of precursers to mRNA by the spliceosome
    • Gesteland, R.F. and Atkins. J.F., eds, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Moore. M.J., Query, C.C. and Sharp, P.A. (1993) Splicing of precursers to mRNA by the spliceosome. In Gesteland, R.F. and Atkins. J.F., eds, The RNA World. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp.303-357.
    • (1993) The RNA World , pp. 303-357
    • Moore, M.J.1    Query, C.C.2    Sharp, P.A.3
  • 6
    • 0024024030 scopus 로고
    • 'Snurps'
    • Steitz, J.A. (1988) 'Snurps'. Sci. Am., 258, 56-60.
    • (1988) Sci. Am. , vol.258 , pp. 56-60
    • Steitz, J.A.1
  • 7
    • 0023288548 scopus 로고
    • Splicing of messenger RNA precursors
    • Sharp, P.A. (1987) Splicing of messenger RNA precursors. Science, 235, 766-771.
    • (1987) Science , vol.235 , pp. 766-771
    • Sharp, P.A.1
  • 8
    • 0022133074 scopus 로고
    • U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing
    • Black, D.L., Chabot, B. and Stetitz, J.A. (1985) U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing. Cell, 42, 737-750.
    • (1985) Cell , vol.42 , pp. 737-750
    • Black, D.L.1    Chabot, B.2    Stetitz, J.A.3
  • 9
    • 0025742986 scopus 로고
    • Base pairing between U2 and U6 snRNAs is necessary for splicing of a mammalian pre-mRNA
    • Wu, J.A. and Manley, J.L. (1991) Base pairing between U2 and U6 snRNAs is necessary for splicing of a mammalian pre-mRNA. Nature, 352. 818-821.
    • (1991) Nature , vol.352 , pp. 818-821
    • Wu, J.A.1    Manley, J.L.2
  • 10
    • 0023392946 scopus 로고
    • The natural 5′ splice site of simian virus 40 large T antigen can he improved by increasing the base complementarity to U1 RNA
    • Zhuang, Y., Leung, H. and Weiner, A.M. (1987) The natural 5′ splice site of simian virus 40 large T antigen can he improved by increasing the base complementarity to U1 RNA. Mol. Cell. Biol., 7, 3018-3020.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 3018-3020
    • Zhuang, Y.1    Leung, H.2    Weiner, A.M.3
  • 11
    • 0024744567 scopus 로고
    • A compensatory hase change in human U2 snRNA can suppress a branch site mutation
    • Zhuang, Y. and Weiner, A.M. (1989) A compensatory hase change in human U2 snRNA can suppress a branch site mutation. Genes Dev., 3, 1545-1552.
    • (1989) Genes Dev. , vol.3 , pp. 1545-1552
    • Zhuang, Y.1    Weiner, A.M.2
  • 12
    • 0023449728 scopus 로고
    • Spliceosome assembly in yeast
    • Cheng, S.C. and Abelson, J. (1987) Spliceosome assembly in yeast. Genes Der., 1, 1014-1027.
    • (1987) Genes Der. , vol.1 , pp. 1014-1027
    • Cheng, S.C.1    Abelson, J.2
  • 13
    • 0023672447 scopus 로고
    • Spliceosome assembly involves the binding and release of U4 small nuclear ribonucleoprotein
    • Lamond, A.I., Konarska, M.M., Grabowski, P.J. and Shaip, P.A. (1988) Spliceosome assembly involves the binding and release of U4 small nuclear ribonucleoprotein. Proc. Natl. Acad. Sci. USA, 85, 411-415.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 411-415
    • Lamond, A.I.1    Konarska, M.M.2    Grabowski, P.J.3    Shaip, P.A.4
  • 14
    • 0022997930 scopus 로고
    • Electrophoresis of ribonucleoproteins reveals an ordered assembly pathway of yeast splicing complexes
    • Pikielny, C.W., Rymond, B.C. and Rosbash, M. (1986) Electrophoresis of ribonucleoproteins reveals an ordered assembly pathway of yeast splicing complexes. Nature, 324, 341-345.
    • (1986) Nature , vol.324 , pp. 341-345
    • Pikielny, C.W.1    Rymond, B.C.2    Rosbash, M.3
  • 15
    • 0025941556 scopus 로고
    • U4 small nuclear RNA dissociates from a yeast Spliceosome and does not participate in the subsequent splicing reaction
    • Yean, S.L. and Lin, R.J. (1991) U4 small nuclear RNA dissociates from a yeast Spliceosome and does not participate in the subsequent splicing reaction. Mol. Cell. Biol., 11, 5571-5577.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5571-5577
    • Yean, S.L.1    Lin, R.J.2
  • 16
    • 0025821210 scopus 로고
    • Genetic evidence for base pairing between U2 and U6 snRNA in mammalian snRNA splicing
    • Dalta, B. and Weiner, A.M. (1991) Genetic evidence for base pairing between U2 and U6 snRNA in mammalian snRNA splicing. Nature, 352, 821-824.
    • (1991) Nature , vol.352 , pp. 821-824
    • Dalta, B.1    Weiner, A.M.2
  • 17
    • 0025639012 scopus 로고
    • Evidence for base-pairing between mammalian U2 and U6 small nuclear ribonucleoprotein particles
    • Hausner, T.P., Giglio, L.M. and Weiner. A.M. (1990) Evidence for base-pairing between mammalian U2 and U6 small nuclear ribonucleoprotein particles. Genes Dev., 4, 2146-2156.
    • (1990) Genes Dev. , vol.4 , pp. 2146-2156
    • Hausner, T.P.1    Giglio, L.M.2    Weiner, A.M.3
  • 18
    • 0026486883 scopus 로고
    • A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome
    • Madhani, H.D. and Guthrie, C. (1992) A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome. Cell, 71, 803-817.
    • (1992) Cell , vol.71 , pp. 803-817
    • Madhani, H.D.1    Guthrie, C.2
  • 19
    • 0024435576 scopus 로고
    • PRP4: A protein of the yeast U4/U6 small nuclear ribonucleoprotein particle
    • Banroques, J. and Abelson, J.N. (1989) PRP4: a protein of the yeast U4/U6 small nuclear ribonucleoprotein particle. Mol. Cell. Biol., 9, 3710-3719.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 3710-3719
    • Banroques, J.1    Abelson, J.N.2
  • 20
    • 0024465586 scopus 로고
    • PRP4 (RNA4) from Saccharomyces cerevisiae: Its gene product is associated with the U4/U6 small nuclear ribonucleoprotein particle
    • Bjørn, S.P., Soltyk, A., Beggs, J.D. and Friesen, J.D. (1989) PRP4 (RNA4) from Saccharomyces cerevisiae: its gene product is associated with the U4/U6 small nuclear ribonucleoprotein particle. Mol. Cell. Biol., 9, 3698-3709.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 3698-3709
    • Bjørn, S.P.1    Soltyk, A.2    Beggs, J.D.3    Friesen, J.D.4
  • 21
    • 0023462892 scopus 로고
    • Evidence for related functions of the RNA genes of Saccharomvces cerevisiae
    • Last, R.L., Maddock, J.M. and Woolford, J.L.,Jr (1987) Evidence for related functions of the RNA genes of Saccharomvces cerevisiae. Genetics, 117, 619-631.
    • (1987) Genetics , vol.117 , pp. 619-631
    • Last, R.L.1    Maddock, J.M.2    Woolford Jr., J.L.3
  • 22
    • 0025224525 scopus 로고
    • The yeast PRP6 gene encodes a U4/U6 small nuclear ribonucleoprotein particle (snRNP) protein, and the PRP9 gene encodes a protein required for U2 snRNP binding
    • Abovich, N., Legrain, P. and Rosbash, M. (1990) The yeast PRP6 gene encodes a U4/U6 small nuclear ribonucleoprotein particle (snRNP) protein, and the PRP9 gene encodes a protein required for U2 snRNP binding. Mol. Cell. Biol., 10. 6417-6425.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 6417-6425
    • Abovich, N.1    Legrain, P.2    Rosbash, M.3
  • 23
    • 0025906517 scopus 로고
    • Suppressors of a U4 snRNA mutation define a novel U6 snRNP protein with RNA-binding motifs
    • Shannon, K. W. and Guthrie, C. (1991) Suppressors of a U4 snRNA mutation define a novel U6 snRNP protein with RNA-binding motifs. Genes Dev., 5, 773-785.
    • (1991) Genes Dev. , vol.5 , pp. 773-785
    • Shannon, K.W.1    Guthrie, C.2
  • 24
    • 0026663165 scopus 로고
    • PRP38 encodes a yeast protein required for pre-mRNA splicing and maintenance of stable U6 small nuclear RNA levels
    • Blanton, S., Srinivasan, A. and Rymond, B.C. (1992) PRP38 encodes a yeast protein required for pre-mRNA splicing and maintenance of stable U6 small nuclear RNA levels. Mol Cell. Biol, 12, 3939-3947.
    • (1992) Mol Cell. Biol , vol.12 , pp. 3939-3947
    • Blanton, S.1    Srinivasan, A.2    Rymond, B.C.3
  • 25
    • 0027238743 scopus 로고
    • The biochemical defects of prp4-1 and prp6-1 yeast splicing mutants reveal that the PRP6 protein is required for the accumulation of the [U4/U6.U5] tri-snRNP
    • Galisson, F. and Legrain, P. (1993) The biochemical defects of prp4-1 and prp6-1 yeast splicing mutants reveal that the PRP6 protein is required for the accumulation of the [U4/U6.U5] tri-snRNP. Nucleic Acids Res., 21, 1555-1562.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 1555-1562
    • Galisson, F.1    Legrain, P.2
  • 26
    • 0028291638 scopus 로고
    • Mutational analysis of the PRP4 protein of Saccharomyces cerevisiae suggests domain structure and snRNP interactions
    • Hu, J., Xu Y., Schappert, K., Harrington,T, Wang, A., Braga, R., Mogridge, J. and Friesen. J.D. (1994) Mutational analysis of the PRP4 protein of Saccharomyces cerevisiae suggests domain structure and snRNP interactions. Nucleic-Acids Res., 22, 1724-1734.
    • (1994) Nucleic-Acids Res. , vol.22 , pp. 1724-1734
    • Hu, J.1    Xu, Y.2    Schappert, K.3    Harrington, T.4    Wang, A.5    Braga, R.6    Mogridge, J.7    Friesen, J.D.8
  • 27
    • 0025336899 scopus 로고
    • Domains of yeast U4 spliceosomal RNA required for PRP4 protein binding, snRNP-snRNP interactions, and pre-mRNA splicing in vivo
    • Bordonne, R., Banroques, J., Abelson, J. and Guthrie, C. (1990) Domains of yeast U4 spliceosomal RNA required for PRP4 protein binding, snRNP-snRNP interactions, and pre-mRNA splicing in vivo. Genes Der., 4, 1185-1196.
    • (1990) Genes Der. , vol.4 , pp. 1185-1196
    • Bordonne, R.1    Banroques, J.2    Abelson, J.3    Guthrie, C.4
  • 28
    • 0024965011 scopus 로고
    • The product of the PRP4 gene of S. cerevisiae shows homology to β subunits of G proteins
    • Dalrymple, M.A., Bjørn, S.P., Friesen, J.D. and Beggs. J.D. (1989) The product of the PRP4 gene of S. cerevisiae shows homology to β subunits of G proteins. Cell, 58, 811-812.
    • (1989) Cell , vol.58 , pp. 811-812
    • Dalrymple, M.A.1    Bjørn, S.P.2    Friesen, J.D.3    Beggs, J.D.4
  • 29
    • 0028076764 scopus 로고
    • The ancient regulatory-protein family of WD-repeat proteins
    • published erratum appears in Nature (1994) Oct 27; 371(6500). 812
    • Neer, E.J., Schmidt. C.J., Nambudripad, R. and Smith, T.F. (1994) The ancient regulatory-protein family of WD-repeat proteins [published erratum appears in Nature (1994) Oct 27; 371(6500). 812]. Nature. 371, 297-300.
    • (1994) Nature , vol.371 , pp. 297-300
    • Neer, E.J.1    Schmidt, C.J.2    Nambudripad, R.3    Smith, T.F.4
  • 33
    • 0029029232 scopus 로고
    • Nuclear localization signals overlap DNA- Or RNA-binding domains in nucleic acid-binding proteins
    • LaCasse, E.C. and Lefehvre, Y.A. (1995) Nuclear localization signals overlap DNA- or RNA-binding domains in nucleic acid-binding proteins. Nucleic Acids Res., 23, 1647-1656.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 1647-1656
    • LaCasse, E.C.1    Lefehvre, Y.A.2
  • 34
    • 0028360767 scopus 로고
    • A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction
    • Gozani, O., Patton, J.G. and Reed, R. (1994) A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction. EMBO J., 13, 3356-3367.
    • (1994) EMBO J. , vol.13 , pp. 3356-3367
    • Gozani, O.1    Patton, J.G.2    Reed, R.3
  • 35
    • 0025951304 scopus 로고
    • Immunoaffinity purification of a (U4/U6/U5) tri-snRNP from human cells
    • Behrens, S.E. and Lührmann, R. (1991) Immunoaffinity purification of a (U4/U6/U5) tri-snRNP from human cells. Genes Dev., 5, 1439-1452.
    • (1991) Genes Dev. , vol.5 , pp. 1439-1452
    • Behrens, S.E.1    Lührmann, R.2
  • 36
    • 0026346182 scopus 로고
    • Using protein affinity chromatography to probe structure of protein machines
    • Formosa, T, Barry, J., Alberts, B. M. and Greenblatt, J. (1991) Using protein affinity chromatography to probe structure of protein machines. Methods Enzymol., 208, 24-45.
    • (1991) Methods Enzymol. , vol.208 , pp. 24-45
    • Formosa, T.1    Barry, J.2    Alberts, B.M.3    Greenblatt, J.4
  • 37
    • 0026690571 scopus 로고
    • A new approach to protein fold recognition
    • Jones, D.T., Taylor, W.R. and Thornton, J.M. (1992) A new approach to protein fold recognition. Nature, 358, 86-89.
    • (1992) Nature , vol.358 , pp. 86-89
    • Jones, D.T.1    Taylor, W.R.2    Thornton, J.M.3
  • 38
    • 0027136282 scopus 로고
    • Comparative protein modelling by satisfaction of spatial restraints
    • Sali, A. and Blundell, T.L. (1993) Comparative protein modelling by satisfaction of spatial restraints. J. Mol. Biol, 234, 779-815.
    • (1993) J. Mol. Biol , vol.234 , pp. 779-815
    • Sali, A.1    Blundell, T.L.2
  • 39
    • 0022907583 scopus 로고
    • The yeast RNA gene products are essential for mRNA splicing in vitro
    • Lustig, A.J., Lin, R.J. and Abelson, J. (1986) The yeast RNA gene products are essential for mRNA splicing in vitro. Cell, 47, 953-963.
    • (1986) Cell , vol.47 , pp. 953-963
    • Lustig, A.J.1    Lin, R.J.2    Abelson, J.3
  • 40
    • 0027428138 scopus 로고
    • Four yeast spliceosomal proteins (PRP5, PRP9, PRP11 and PRP21) interact to promote U2 snRNP binding to pre-mRNA
    • Ruby, S.W., Chang, T.H. and Abelson, J. (1993) Four yeast spliceosomal proteins (PRP5, PRP9, PRP11 and PRP21) interact to promote U2 snRNP binding to pre-mRNA. Genes Dev., 7, 1909-1925.
    • (1993) Genes Dev. , vol.7 , pp. 1909-1925
    • Ruby, S.W.1    Chang, T.H.2    Abelson, J.3
  • 41
    • 0031016867 scopus 로고    scopus 로고
    • Mutations within the yeast U4//U6 snRNP protein Prp4 affect a late stage of spliceosome assembly
    • Ayadi, L., Miller, M. and Banrodues, J. (1997) Mutations within the yeast U4//U6 snRNP protein Prp4 affect a late stage of spliceosome assembly. RNA, 3, 197-209.
    • (1997) RNA , vol.3 , pp. 197-209
    • Ayadi, L.1    Miller, M.2    Banrodues, J.3
  • 44
    • 0026605537 scopus 로고
    • CLUSTAL V: Improved software for multiple sequence alignment
    • Higgins, D.G., Bleasby, A.J. and Fuchs, R. (1992) CLUSTAL V: improved software for multiple sequence alignment. Comp. Appl. Biosci., 8, 189-191.
    • (1992) Comp. Appl. Biosci. , vol.8 , pp. 189-191
    • Higgins, D.G.1    Bleasby, A.J.2    Fuchs, R.3
  • 45
    • 0003448569 scopus 로고
    • Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Harlow, E. and Lane, D. (1988) Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (1988) Antibodies: A Laboratory Manual
    • Harlow, E.1    Lane, D.2
  • 46
    • 0025279437 scopus 로고
    • Efficient production of chicken egg yolk antibodies against a conserved mammalian protein
    • Gassmann, M., Thommes, P., Weiser, T. and Hubscher. U. (1990) Efficient production of chicken egg yolk antibodies against a conserved mammalian protein. FASEB J., 4, 2528-2532.
    • (1990) FASEB J. , vol.4 , pp. 2528-2532
    • Gassmann, M.1    Thommes, P.2    Weiser, T.3    Hubscher, U.4
  • 47
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J.D., Lebovitz, R.M. and Roeder, R.G. (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res., 11, 1475-1489.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 48
    • 0025333058 scopus 로고
    • Small-scale preparation of extracts from radiolabeled cells efficient in pre-mRNA splicing
    • Lee, K.A. and Green. M.R. (1990) Small-scale preparation of extracts from radiolabeled cells efficient in pre-mRNA splicing. Methods Enzymol., 181, 20-30.
    • (1990) Methods Enzymol. , vol.181 , pp. 20-30
    • Lee, K.A.1    Green, M.R.2
  • 49
    • 0025346005 scopus 로고
    • Immunological methods for purification and characterization of heterogeneous nuclear ribonucleoprotein particles
    • Pinol, R.S., Choi, Y.D. and Dreyfuss, G. (1990) Immunological methods for purification and characterization of heterogeneous nuclear ribonucleoprotein particles. Methods Enzymol., 181, 317-325.
    • (1990) Methods Enzymol. , vol.181 , pp. 317-325
    • Pinol, R.S.1    Choi, Y.D.2    Dreyfuss, G.3
  • 50
    • 0028881597 scopus 로고
    • Mutational analysis of Saccharomyces cerevisiae U4 small nuclear RNA identifies functionally important domains
    • Hu, J., Xu, D., Schappert, K., Xu, Y and Friesen, J.D. (1995) Mutational analysis of Saccharomyces cerevisiae U4 small nuclear RNA identifies functionally important domains. Mol Cell. Biol., 15. 1274-1285.
    • (1995) Mol Cell. Biol. , vol.15 , pp. 1274-1285
    • Hu, J.1    Xu, D.2    Schappert, K.3    Xu, Y.4    Friesen, J.D.5
  • 51
    • 0027050011 scopus 로고
    • Sequence-structure matching in globular proteins: Application to supersecondary and tertiary structure determination
    • Godzik, A. and Skolnick, J. (1992) Sequence-structure matching in globular proteins: application to supersecondary and tertiary structure determination. Proc. Natl. Acad. Sci. USA, 89, 12098-12102.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 12098-12102
    • Godzik, A.1    Skolnick, J.2
  • 52
    • 0027650879 scopus 로고
    • Boltzmunn's principle, knowledge-based mean fields and protein folding. An approach to the computational determination of protein structures
    • Sippl, M.J. (1993) Boltzmunn's principle, knowledge-based mean fields and protein folding. An approach to the computational determination of protein structures. J. Comp. Aided Mol. Des., 7, 473-501.
    • (1993) J. Comp. Aided Mol. Des. , vol.7 , pp. 473-501
    • Sippl, M.J.1
  • 53
    • 0027318317 scopus 로고
    • An empirical energy function for threading protein sequence through the folding motif
    • Bryant, S.H. and Lawrence, C.E. (1993) An empirical energy function for threading protein sequence through the folding motif. Proteins, 16, 92-112.
    • (1993) Proteins , vol.16 , pp. 92-112
    • Bryant, S.H.1    Lawrence, C.E.2


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