The evolving portrait of cancer metastasis

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 70, Issue , 2005, Pages 291-297

  Gupta, P B ^a,b   Mani, S ^b   Yang, J ^b   Hartwell, K ^a,b   Weinberg, R A ^a,b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELL; CANCER INVASION; CARCINOGENESIS; CELL TRANSFORMATION; CONFERENCE PAPER; HUMAN; MELANOMA; METASTASIS; METASTASIS POTENTIAL; PRIORITY JOURNAL; STEM CELL; TISSUE MICROARRAY; TUMOR GROWTH; ARTICLE; CANCER GROWTH; CONCEPTUAL FRAMEWORK; DARWINIAN MODEL; GENETIC PARAMETERS; PHENOTYPE; TUMOR INVASION;

ANIMALS; EPIGENESIS, GENETIC; EPITHELIUM; GENE EXPRESSION PROFILING; HUMANS; MELANOMA; MESODERM; MODELS, GENETIC; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

TRANSFORMING GROWTH FACTOR; UVOMORULIN; WNT PROTEIN;

EID: 33746387371     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.2005.70.033     Document Type: Conference Paper

References (50)

1. Bounacer A., McGregor A., Skinner J., Bond J., Poghosyan Z., and Wynford-Thomas D. 2004. Mutant ras-induced proliferation of human thyroid epithelial cells requires three effector pathways. Oncogene 23: 7839.
2. Cheung M., Chaboissier M.C., Mynett A., Hirst E., Schedl A., and Briscoe J. 2005. The transcriptional control of trunk neural crest induction, survival, and delamination. Dev. Cell 8: 179.
3. Chung G.T., Sundaresan V., Hasleton P., Rudd R., Taylor R., and Rabbitts P.H. 1996. Clonal evolution of lung tumors. Cancer Res. 56: 1609.
4. Dimri G.P. and Campisi J. 1994. Molecular and cell biology of replicative senescence. Cold Spring Harbor Symp. Quant. Biol. 59: 67.
5. Dowell J.E. 2003. Cancer from an unknown primary site. Am. J. Med. Sci. 326: 35.
6. Ehlert J.E. and Kubbutat M.H. 2001. Apoptosis and its relevance in cancer therapy. Onkologie 24: 433.
7. Elenbaas B., Spirio L., Koerner F., Fleming M.D., Zimonjic D.B., Donaher J.L., Popescu N.C., Hahn W.C., and Weinberg R.A. 2001. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes Dev. 15: 50.
8. Glinsky G.V., Higashiyama T., and Glinskii A.B. 2004a. Classification of human breast cancer using gene expression profiling as a component of the survival predictor algorithm. Clin. Cancer Res. 10: 2272.
9. Glinsky G.V., Glinskii A.B., Stephenson A.J., Hoffman R.M., and Gerald W.L. 2004b. Gene expression profiling predicts clinical outcome of prostate cancer. J. Clin. Invest. 113: 913.
10. Goel A., Arnold C.N., Niedzwiecki D., Chang D.K., Ricciardiello L., Carethers J.M., Dowell J.M., Wasserman L., Compton C., Mayer R.J., Bertagnolli M.M., and Boland C.R. 2003. Characterization of sporadic colon cancer by patterns of genomic instability. Cancer Res. 63: 1608.
11. Golub T.R., Slonim D.K., Tamayo P., Huard C., Gaasenbeek M., Mesirov J.P., Coller H., Loh M.L., Downing J.R., Caligiuri M.A., Bloomfield C.D., and Landes E.S. 1999. Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring. Science 286: 531.
12. Grady W.M. 2004. Genomic instability and colon cancer. Cancer Metastasis Rev. 23: 11.
13. Gupta P.B., Kuperwasser C., Brunet J.P., Ramaswamy S., Kuo W.L., Gray J.W., Naber S.P., and Weinberg R.A. 2005. The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat. Genet. 37: 1047.
14. Hahn W.C., Counter C.M., Lundberg A.S., Beijersbergen R.L., Brooks M.W., and Weinberg R.A. 1999. Creation of human tumour cells with defined genetic elements. Nature 400: 464.
15. Harley C.B. 1991. Telomere loss: Mitotic clock or genetic time bomb? Mutat. Res. 256: 271.
16. Hiyama T., Tanaka S., Yoshihara M., Sasao S., Kose K., Shima H., Tuncel H., Ueno Y., Ito M., Kitadai Y., Yasui W., Haruma K., and Chayama K. 2004. Chromosomal and microsatellite instability in sporadic gastric cancer. J. Gastroenterol. Hepatol. 19: 756.
17. Huang E., Cheng S.H., Dressman H., Pittman J., Tsou M.H., Horng C.F., Bild A., Iversen E.S., Liao M., Chen C.M., West M., Nevins J.R., and Huang A.T. 2003. Gene expression predictors of breast cancer outcomes. Lancet 361: 1590.
18. Kemler R., Hierholzer A., Kanzler B., Kuppig S., Hansen K., Taketo M.M., de Vries W.N., Knowles B.B., and Solter D. 2004. Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast. Development 131: 5817.
19. Kirkin V., Joos S., and Zornig M. 2004. The role of Bcl-2 family members in tumorigenesis. Biochim. Biophys. Acta 1644: 229.
20. Lawrence J.A. and Steeg P.S. 1996. Mechanisms of tumor invasion and metastasis. World J. Urol. 14: 124.
21. Lengauer C., Kinzler K.W., and Vogelstein B. 1997. Genetic instability in colorectal cancers. Nature 386: 623.
22. Li G., Tang L., Zhou X., Tron V., and Ho V. 1998. Chemotherapy-induced apoptosis in melanoma cells is p53 dependent. Melanoma Res. 8: 17.
23. Lundberg A.S., Randell S.H., Stewart S.A., Elenbaas B., Hartwell K.A., Brooks M.W., Fleming M.D., Olsen J.C., Miller S.W., Weinberg R.A., and Hahn W.C. 2002. Immortalization and transformation of primary human airway epithelial cells by gene transfer. Oncogene 21: 4577.
24. Martinez-Alvarez C., Blanco M.J., Perez R., Rabadan M.A., Aparicio M., Resel E., Martinez T., and Nieto M.A. 2004. Snail family members and cell survival in physiological and pathological cleft palates. Dev. Biol. 265: 207.
25. Mertens F., Heim S., Mandahl N., Johansson B., Mertens O., Persson B., Salemark L., Wennerberg J., Jonsson N., and Mitelman F. 1991. Cytogenetic analysis of 33 basal cell carcinomas. Cancer Res. 51: 954.
26. Milovic M., Popov I., and Jelic S. 2002. Tumor markers in metastatic disease from cancer of unknown primary origin. Med. Sci. Monit. 8: MT25 .
27. Mora J., Cheung N.K., and Gerald W.L. 2001. Genetic heterogeneity and clonal evolution in neuroblastoma. Br. J. Cancer 85: 182.
28. Nutt C.L., Mani D.R., Betensky R.A., Tamayo P., Cairncross J.G., Ladd C., Pohl U., Hartmann C., McLaughlin M.E., Batchelor T.T., Black P.M., von Deimling A., Pomeroy S.L., Golub T.R., and Louis D.N. 2003. Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. Cancer Res. 63: 1602.
29. Oft M., Heider K.H., and Beug H. 1998. TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis. Curr. Biol. 8: 1243.
30. Pavlidis N., Briasoulis E., Hainsworth J., and Greco F.A. 2003. Diagnostic and therapeutic management of cancer of an unknown primary. Eur. J. Cancer 39: 1990.
31. Ramaswamy S., Ross K.N., Lander E.S., and Golub T.R. 2003. A molecular signature of metastasis in primary solid tumors. Nat. Genet. 33: 49.
32. Ramaswamy S., Tamayo P., Rifkin R., Mukherjee S., Yeang C.H., Angelo M., Ladd C., Reich M., Latulippe E., Mesirov J.P. Poggio T., Gerald W., Loda M., Lander E.S., and Golub T.R. 2001. Multiclass cancer diagnosis using tumor gene expression signatures. Proc. Natl. Acad. Sci. 98: 15149.
33. Rich J.N., Guo C., McLendon R.E., Bigner D.D., Wang X.F., and Counter C.M. 2001. A genetically tractable model of human glioma formation. Cancer Res. 61: 3556.
34. Sage J., Mulligan G.J., Attardi L.D., Miller A., Chen S., Williams B., Theodorou E., and Jacks T. 2000. Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev. 14: 3037.
35. Savagner P., Kusewitt D.F., Carver E.A., Magnino F., Choi C., Gridley T., and Hudson L.G. 2005. Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes. J. Cell. Physiol. 202: 858.
36. Schleger C., Heck R., and Steinberg P. 2000. The role of wild-type and mutated N-ras in the malignant transformation of liver cells. Mol. Carcinog. 28: 31.
37. Shih I.M., Zhou W., Goodman S.N., Lengauer C., Kinzler K.W., and Vogelstein B. 2001. Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis. Cancer Res. 61: 818.
38. Sidransky D., Mikkelsen T., Schwechheimer K., Rosenblum M.L., Cavanee W., and Vogelstein B. 1992. Clonal expansion of p53 mutant cells is associated with brain tumour progression. Nature 355: 846.
39. Stracke M.L. and Liotta L.A. 1992. Multi-step cascade of tumor cell metastasis. In Vivo 6: 309.
40. Tanaka T., Saika S., Ohnishi Y., Ooshima A., McAvoy J.W., Liu C.Y., Azhar M., Doetschman T., and Kao W.W. 2004. Fibroblast growth factor 2: Roles of regulation of lens cell proliferation and epithelial-mesenchymal transition in response to injury. Mol. Vis. 10: 462.
41. Thiery J.P. 2003. Epithelial-mesenchymal transitions in development and pathologies. Curr. Opin. Cell Biol. 15: 740.
42. Thiery J.P. and Chopin D. 1999. Epithelial cell plasticity in development and tumor progression. Cancer Metastasis Rev. 18: 31.
43. Urquidi V., Tarin D., and Goodison S. 2000. Role of telomerase in cell senescence and oncogenesis. Annu. Rev. Med. 51: 65.
44. van de Vijver M.J., He Y.D., van 't Veer L.J., Dai H., Hart A.A., Voskuil D.W., Schreiber G.J., Peterse H.L., Roberts C., Marton M.J., Parrish M., Atsma D., Witteveen A.T., Glas A., Delahaye L., van der Velde T., Bartelink H., Rodenhuis S., Rutgers E.T., Friend S.H., and Bernards R. 2002. A gene-expression signature as a predictor of survival in breast cancer. N. Engl. J. Med. 347: 1999.
45. van 't Veer L.J., Dai H., van de Vijver M.J., He Y.D., Hart A.A., Mao M., Peterse H.L., van der Kooy K., Marton M.J., Witteveen A.T., Schreiber G.J., Kerkhoven R.M., Roberts C., Linsley P.S., Bernards R., and Friend S.H. 2002. Gene expression profiling predicts clinical outcome of breast cancer. Nature 415: 530.
46. Wang Y., Klijn J.G., Zhang Y., Sieuwerts A.M., Look M.P., Yang F., Talantov D., Timmermans M., Meijer-van Gelder M.E., Yu J., Jatkoe T., Berns E.M., Atkins D., and Foekens J.A. 2005. Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet 365: 671.
47. Wolman S.R. 1983. Karyotypic progression in human tumors. Cancer Metastasis Rev. 2: 257.
48. _. 1986. Cytogenetic heterogeneity: Its role in tumor evolution. Cancer Genet. Cytogenet. 19: 129.
49. Wynford-Thomas D. 1999. Cellular senescence and cancer. J. Pathol. 187: 100.
50. Yoon S.O., Park S.J., Yun C.H. and Chung A.S. 2003. Roles of matrix metalloproteinases in tumor metastasis and angiogenesis. J. Biochem. Mol. Biol. 36: 128.