Mechanisms of tumor invasion and metastasis

World Journal of Urology

Volumn 14, Issue 3, 1996, Pages 124-130

  Lawrence, J A ^a   Steeg, P S ^a   Institute, National Cancer ^a  

^a Laboratory of Pathology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE;

ANIMAL; CANCER INVASION; CANCER STEM CELL; CELL ADHESION; CHEMOTAXIS; HUMAN; METASTASIS; NEOVASCULARIZATION (PATHOLOGY); PHYSIOLOGY; REVIEW;

ANIMALS; CELL ADHESION; CHEMOTAXIS; ENDOPEPTIDASES; HUMANS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; TUMOR STEM CELLS;

EID: 0029681993     PISSN: 07244983     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00186891     Document Type: Article

References (84)

1. Barsky SH (1983) Loss of basement membrane components by invasive tumors but not by their benign counterparts. Lab Invest 49:140-147
2. Bellusci S, Moens G, Gaudino G, Comoglio P, Nakamura T, Thiery JP, Jouanneau J ( 1994) Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity. Oncogene9: 1091-1099
3. Birchmeier W, Weidner KM, Hulksen J, Behrens J (1993) Molecular mechanisms leading to cell junction (cadherin) deficiency in invasive carcinomas. Semin Cancer Biol 4:231-239
4. Blasi F (1993) Urokinase and urokinase receptor: a paracrine/ autocrine system regulating cell migration and invasiveness. Bioessays 15:105-111
5. Blood CH. Zetter BR (1990) Tumor interactions with the vasculature: angiogenesis and tumor metastasis. Biochim Biophys Acta 1032:89-118
6. Boyer B. Dufour S, Thiery JP (1992) E-cadherin expression during the acidic-FGF induced dispersion of a rat bladder carcinoma cell line. Exp Cell Res 201:347-357
7. Brawer MK. Deering RE, Brown M, Preston SD, Bigler SA (1994) Predictors of pathologic stage in prostate carcinoma. The role of neovascularity. Cancer 73:678-687
8. Brooks PC, Montogomery AM, Rosenfeld M, Reisfeld RA, Hu T, Killer G, and Cheresh DA (1994) Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79:1157-1164
9. Chiu JJS. Cowan K (1993) Differential effect of interleukin-6 on estrogen receptor positive and negative breast carcinoma cell lines. Proc Am Assoc Cancer Res 34:55
10. Coman DR, Sheldon WF (1946) The significance of hyperemia around tumor implants. Am J Pathol 22:821-826
11. Crowley CW, Cohen RL, Lucas BK, Liu G, Shuman MA, Levinson AD ( 1993) Prevention of metastasis by inhibition of the urokinase receptor. Proc Natl Acad Sci USA 90:50215025
12. deCleck YA, Yean T-D, Ratzkin BJ, Lu HS, Langley KE ( 1989) Purification and characterization of two related but distinct metalloproteinase inhibitors secreted by bovine aortic endothelial cells. J Biol Chem 264:17445-17453
13. Dedhar S (1990) Integrins and tumor invasion. Bioessays 12: 583-590
14. Dedhar S. Saulnier R, Nagle R, Overall CM (1993) Specific alterations in the expression of alpha 3 beta 1 and alpha 6 beta 4 integrins in highly invasive and metastatic variants of human prostate carcinoma cells selected by in vitro invasion through reconstituted basement membrane. Clin Exp Metastasis 11:391400
15. DeLaRosa A, Williams RL, Steeg PS (1995) Nm23/nucleoside diphosphate kinases: toward a structural and biochemical understanding of its biological functions. Bioessays 17:53-62
16. Dickinson AJ, Fox SB, Persad RA, Hollyer J, Sibley GN, Harris AL (1994) Quantification of angiogenesis as an independent predictor of prognosis in invasive bladder carcinomas. Br J U rol 74:762-766
17. Docherty AJP, Lyons A, Smith BJ, Wright EM, Stephens PE, Harris TJ, Murphy G, Reynolds JJ (1985) Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity. Nature 318:66-69
18. Dong J-T, Lamb PW, Rinker-Schaeffer CW, Vukanovic J, Ichikawa T, Isaacs JT, Barret JC (1995) KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11 p 11.2. Science 268:884-886
19. Dvorak HF, Senger DR, Dvorak AM (1983) Fibrin as a component of the tumor stroma: origins and biological significance. Cancer Metastasis Rev 2:41-73
20. Effert PJ, Neubauer A, Walther PJ, Liu ET (1992) Alterations of the p53 gene are associated with the progression of a human prostate carcinoma. J Urol 147:789-793
21. Fregene TA, Khanuja PS, Noto AC, Gehani SK, Egmont EMV, Luz DA, Pienta KL (1993) Tumor-associated angiogenesis in prostate cancer. Anticancer Res 13:2377-2381
22. Freije JM, Diez-Itza I, Balbin M, Sanchez LM, Blasco R, Tolivia J. Lopez-Otin C ( 1994) Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas. J Biol Chem 269: 16766-16773
23. Frisch SM, Francis H (1994) Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 124:619-626
24. Fujita S, Suzuki H, Kinoshita M, Hiroashi S (1992) Inhibition of cell attachment, invasion and metastasis of human carcinoma cell lines by anti-integrin beta 1 subunit antibody. Jpn J Cancer 83: 1317-1326
25. Hall MC, Troncoso P, Pollack A, Zhau HY, Zagars GK, Chung LW, Eschenbach AC (1994) Significance of tumor angiogenesis in clinically localized prostate carcinoma treated with external beam radiotherapy. Urology 44:869-875
26. Hammersen F, Endrich B, Messmer K (1985) The fine structure of tumor blood vessels. Int J Microcircul 4:31-34
27. Hynes RO, Lander AD (1992) Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons. Cell 63:303-322
28. Ichikawa T, Ichikawa Y, Dong J, Hawkins AL, Griffin CA, Isaacs WB, Oshimura M, Barren JC, Isaacs JT (1992) Localization of metastasis suppressor gene for prostatic cancer to the short arm of human chromosome 11. Cancer Res 52:3486-3490
29. Ingber DE (1991) Control of capillary growth and differentiation by extracellular matrix. Use of tensegrity mechanism for signal processing. Chest 99:34S-40S
30. Ingber D, Fujita T, Kishimoto S, Sudo K, Kanamaru T, Brem H, Folkman J (1990) Synthetic analogues of funagillin that inhibit angiogenesis and suppress tumor growth. Nature 348: 555-557
31. Jain RK (1988) Determinants of tumor blood flow: a review. Cancer Res 48:2641-2658
32. Jain RK, Ward-Hartley KA (1987) Dynamics of cancer cell interaction with microvascular and interstitium. Biorrheology 24: 117-125
33. Johnson RC, Zhu D, Voss HGA, Pauli BU (1993) Lung endothelial dipeptidyl peptidase IV is an adhesion molecule for lung metastatic rat breast and prostate carcinoma cells. J Cell Biol 121:1423-1432
34. Kantor JD, McCormick B, Steeg PS, Zetter BR (1993) Inhibition of cell motility after nm23 transfection of human and murine tumor cells. Cancer Res 53:1971-1973
35. Katagiri A, Watanabe R, Tomita Y (1995) E-cadherin expression in renal cell cancer and its significance in metastasis and survival. Br J Cancer 71:376-379
36. Leone A, Flatow U, King CR, Sandeen MA, Margulies IMK. Liotta LA, Steegs PS (1991) Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23transfected melanoma cells. Cell 65:25-35
37. Leone A, Flatow U, VanHoutte K, Steeg PS (1993) Transfection of human nm23-Hl into the human MDa-MB-435 breast carcinoma cell line: Effects on tumor metastatic potential, colonization, and enzymatic activity. Oncogene 8:2325-2333
38. Liotta LA, Steeg PS, Stetler-Stevenson WG (1991) Cancer metastasis and angiogenesis: an imbalance of negative and positive regulation. Cell 64:327-336
39. Lu C, Kerbel RS (1993) Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression. J Cell Biol 120: 1281-1288
40. Lu C, Kerbel RS (1994) Cytokines, growth factors and the loss of negative controls in the progression of human cutaneous malignant melanoma. Curr Opin Oncol 6:212-220
41. Lu C, Rak J, Kobayashi H, Kerbel R (1993) Increased resistance to oncostatin M-induced growth inhibition of human melanoma cell lines derived from advanced-stage lesions. Cancer Res 5.3:2708-2711
42. Madri JA, Williams SK (1983) Capillary endothelial cell cultures: phenotypic modulation by matrix components. J Cell Biol 97: 153-165
43. McCormick BA, Zetter BR ( 1992) Adhesive interactions in angiogenesis and metastasis. Pharmacol Ther 53:239-260
44. Miyamoto H, Kubota Y, Shuin T, Torigoe S, Hosaka M, Iwasaki Y, Danenberg K, Danenberg PV (1993) Analyses of p53 gene mutations in primary human bladder cancer. Oncol Res 5:245-249
45. Morita T, Shinohara N, Tikue A (1994) Antitumor effect of a synthetic analogue of fumagillin on murine renal carcinoma. BrJUrol 74:416-421
46. Nguyen NM, Lehr JE, Pienta KJ (1993) Pentostatin inhibits angiogenesis in vitro and suppresses prostate tumor growth in vivo. Anticancer Res 13:2143-2147
47. Nguyen M, Watanabe H, Budson AE, Richie JP, Hayes DF, Folkman J (1994) Elevated levels of angiogenic peptide, basic fibroblast growth factor, in the urine of patients with a wide spectrum of cancers. J Natl Cancer Inst 86:356-361
48. O'Brien T, Cranston D, Fuggle S, Bcknell R, Harris AL (1995) Different angiogenic pathways characterize superficial and invasive bladder cancer. Cancer Res 55:510-513
49. O'Reilly MS, Holmgrem L, Shing Y, Chen C, Rosenthal RA, Moses M, Lane WS, Cao Y, Sage EH, Folkman J (1994) Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastasis by a Lewis lung carcinoma. Cell 79:315-328
50. Ossowski L, Russo-Payne H, Wilson EL (1991) Inhibition of urokinase-type plasminogen activator by antibodies: the effect on dissemination of a human tumor in the nude mouse model. Cancer Res 51:274-281
51. Otto T, Birchmeier W, Schmidt U, Hinke A, Schipper J, Rubben H, Raz A (1994) Inverse relation of E-cadherin and autocrine motility factor receptor expression as a prognostic factor in patients with bladder carcinomas. Cancer Res 54:3120-3123
52. Parhar RS, Shi Y, Zou M, Farid NR, Ernst P, Al-Sedairy S (1995) Effects of cytokine mediated modulation of Nm23 expression on the invasion and metastatic behavior of B16F10 melanoma cells. Int J Cancer 60:204-210
53. Pienta KJ, Naik H, Akhtar A, Yamazaki K, Replogle TS, Lehr J, Donat TL, Tait L, Hogan V, Raz A (1995) Inhibition of spontaneous metastasis in a rat prostate cancer model by administration of modified citrus pectin. J Natl Cancer Inst 87 : 348-353
54. Ries LAG, Miller BA, Hankey BF, Kosary CL, Harras, Edwards BK (1994) Cancer statistics review 1973-1991: Tables and graphs. NIH publication 94-2789. National Cancer Institute, Bethesda, Maryland
55. Rinker-Schaeffer CW, Partin AW, Isaacs WB, Coffey DS, Isaacs JT (1994) Molecular and cellular changes associated with the acquisition of metastatic ability by prostatic cancer cells. Prostate 25:249-265
56. Rinker-Schaeffer CW, Hawkins AL, Ru N, Dong J, Stoica G, Griffin CA, Ichikawa T, Barrett JC, Isaacs JT (1994) Differential suppression of mammary and prostate cancer metastatis by human chromosomes 17 and 11. Cancer Res 54:6249-6256
57. Roberts A, Sporn M (1988) Transforming growth factor beta. Adv Cancer Res 51:107-145
58. Rouslahti E (1991) Integrals. J Clin Invest 87:1-5
59. Rouslahti E, Pierschbacher MD (1987) New perspectives in cell adhesion: ROD and integrins. Science 238:491-497
60. Sato K, Terada K, Sugiyama T, Takahashi S, Saito M, Moriyama M, Kakinuma H, Suzuki Y, Kalo M, Kalo T (1994) Frequent overexpression of vascular endothelial growth factor gene in human renal cell carcinoma. Tohoku J Exp Med 173:355-360
61. Shi I-M, Herlyn M (1993) Role of growth factors and their receptors in the development and progression of melanoma. J Invest Dermatol 100:196S-203S
62. Steeg PS, Bevilacqua G, Kopper L, Thorgeirsson UP, Talmadge JE, Liotta LA, Sobel ME (1988) Evidence for a novel gene associated with low tumor metastatic potential. J Nat Cancer Inst 80:200-204
63. Steiner MS, Zhou ZZ, Tonb DC, Barrack ER (1994) Expression of transforming growth factor-beta 1 in prostate cancer. Endocrinology 135:2240-2247
64. Stetler-Stevenson WG, Krutzsch HC, Liotta LA (1989) TIMP2, a new member of the metalloproteinase inhibitor family. J Biol Chem 264: 17374-17378
65. Stetler-Stevenson W, Liotta L, Kleiner DE Jr ( 1993) Extracellular matrix 6: role of matrix metalloproteinases in tumor invasion and metastasis. FASEB J 7:1434-1441
66. Sugarbaker EV, Thornwaite J, Kelcham AS (1977) Inhibitory effect of a primary tumor on metastasis. In: Day 58 (ed) Progress in cancer research and therapy. Raven, New York, pp 227-240
67. Takahashi A, Sasaki H, Kirn SJ, Tobisu K, Kakizoe T, Tsukamoto T. Kumamoto Y, Sugimura T, Tereda M (1994) Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis. Cancer Res 54: 4233-4237
68. Thompson TC, Park SH, Timme TL, Ren C. Eastham JA, Donehower LA, Bradley A, Kamon D, Yang G (1995) Loss of p53 function leads to metastasis in ras+myc-initiated mouse prostate cancer. Oncogene 10:869-879
69. Totnita Y, Saito T, Saito K, Oite T, Shimizu F, Sato S (1995) Possible significance of VLA-4 (alpha 4 beta 1 ) for hematogenous metastasis of renal cell cancer. Int J Cancer 60:753-758
70. Trousseau A (1865) Phlegmasia alba dolens. Clin Med Hotel Dieu Paris 3:654-655
71. Umbas R, Schalken JA, Aalders TW, Carter BS, Karthaus HFM, Schaafsma EW, Debruyne FMJ, Isaacs WB (1992) Expression of cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer. Cancer Res 52:51045109
72. Uria JA, Ferrando AE, Velasco G, Freije JMP, Lopez-Otin C (1994) Structure expression in breast tumors of human TIMP3, a new member of the metalloproteinase inhibitor family. Cancer Res 54:2091 -2094
73. Vleminckx K, Vakaet L, Mareel M, Fiers W, Roy FV (1991) Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 66:107-119
74. Vukanovic J, Isaacs JT (1995) Linomide inhibits angiogenesis, growth, metastasis, and macrophage infiltration within rat prostatic cancers. Cancer Res 55:1499-1504
75. Warren B A (1979) The vascular morphology of tumors. Tumor blood circulation. CRC, Boca Raton, Florida
76. Warren B A, Shubik P, Feldman R (1978) Metastasis via the bloodstream: the method of intravasation of tumor cell in a transplantable melanoma of the hamster. Cancer Lett 4:245251
77. Weidner N, Semple JP, Welch WR, Folkman J (1991) Tumor angiogenesis and metastasis correlation in invasive breast carcinoma. New Engl J Med 324:1-8
78. Weidner N, Carroll P, Flax J, Blumenfeld W, Folkman J (1993) Tumor aniogenesis correlates with metastasis in invasive prostate cancer. Am J Pathol 143:401-409
79. Weinstat-Saslow D, Steeg P (1994) Angiogenesis and colonization in the tumor metastatic process: basic and applied advances. FASEB J 8:401-408
80. Weinstat-Saslow D, Zabrenetzky V, VanHoutte K, Frazier W, Roberts D, Steeg P (1994) Transfection of thrombospondin-1 cDNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential and angiogenesis. Cancer Res 54:6504-6511
81. Witkowski CM, Rabinovitz I, Nagle RB, Affinito KS, Cress AE (1993) Characterization of integrin subunits, cellular adhesion and tumorgenicity of four human prostate cell lines. J Cancer Res Clin Oncol 119:637-644
82. Witty JP, Lempka T, Coffey RJ, Matrisian LM (1995) Decreased tumor formation in 7,12-dimethylbenzanthracenetreated stromelysin-1 transgenic mice is associated with alterations in mammary epithelial cell apoptosis. Cancer Res 55 : 1401-1406
83. Yanase T, Tamura M, Fujita K, Kodama S, Tanaka K (1993) Inhibitory effect of angiogenesis inhibitor TNP-470 on tumor growth and metastasis of human cell lines in vitro and in vivo. Cancer Res 53:2566-2570
84. Zocchi MR, Ferrero E, Toninelli E, Castellani P, Poggi A, Rugarli C (1994) Expression of N-CAM by human renal cell carcinomas correlates with growth rate and adhesive properties. Exp Cell Res 214:499-509