Structure of complex viruses and virus-infected cells by electron cryo tomography

Current Opinion in Microbiology

Volumn 9, Issue 4, 2006, Pages 437-442

  Grünewald, Kay ^a   Cyrklaff, Marek ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; ENVELOPE PROTEIN;

CRYOPRESERVATION; CYTOLOGY; ELECTRON CRYO TOMOGRAPHY; ELECTRON MICROSCOPY; HERPES SIMPLEX VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS; LIFE CYCLE; MOLECULAR PROBE; MOLONEY LEUKEMIA ONCOVIRUS; NONHUMAN; REVIEW; TOMOGRAPHY; VACCINIA VIRUS; VIRUS INFECTION; VIRUS ISOLATION; VIRUS MORPHOLOGY; VIRUS NUCLEOCAPSID;

ANIMALS; CRYOELECTRON MICROSCOPY; HERPESVIRUS 1, HUMAN; HIV; HUMANS; TOMOGRAPHY; VACCINIA VIRUS; VIRION; VIRUSES;

EID: 33746289829     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mib.2006.06.016     Document Type: Review

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38. ••]. Docking of available crystal structures domains resulted in a model that might explain immune evasion by the virus.
39. •], particularly in the stem region, possibly because of the different image processing methodologies used in the two studies. Atomic resolution structures were fitted into the EM-density and implications of two possible models are discussed.